Inhibition of human chymase by 2-amino-3,1-benzoxazin-4-ones

Bioorganic and Medicinal Chemistry

Volumn 9, Issue 4, 2001, Pages 947-954

  Neumann, Ulf ^a   Schechter, Norman M ^b   Gütschow, Michael ^c  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 3,1 BENZOXAZINONE DERIVATIVE; BENZOXAZINONE DERIVATIVE; CATHEPSIN; CATHEPSIN G; CHYMASE; CHYMOTRYPSIN; ELASTASE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; DEACYLATION; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; THIN LAYER CHROMATOGRAPHY;

ALGORITHMS; ANGIOTENSIN I; ANIMALS; CATHEPSINS; CATTLE; CHYMASES; CHYMOTRYPSIN; HUMANS; KINETICS; LEUKOCYTE ELASTASE; OXAZINES; PROTEASE INHIBITORS; SERINE ENDOPEPTIDASES; TRYPSIN INHIBITORS;

EID: 0035031277     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00310-2     Document Type: Article

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