Generation of species cross-reactive aptamers using "toggle" SELEX

Molecular Therapy

Volumn 4, Issue 6, 2001, Pages 567-573

  White, Rebekah ^a   Rusconi, Christopher ^a   Scardino, Elizabeth ^a   Wolberg, Alisa ^a   Lawson, Jeffrey ^a   Hoffman, Maureane ^a   Sullenger, Bruce ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Anticoagulation; Aptamer; Combinatorial chemistry; Drug development; Species cross reactivity; Thrombin

Indexed keywords

APTAMER; LIGAND; RNA; THROMBIN;

ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CONTROLLED STUDY; CROSS REACTION; DIAGNOSTIC TEST; DRUG ISOLATION; GENE LIBRARY; GENE THERAPY; GENETIC SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; PROTEIN TARGETING; SPECIES; SWINE; THROMBOCYTE ACTIVATION;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0035668696     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0495     Document Type: Article

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