Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate

Journal of Bioenergetics and Biomembranes

Volumn 44, Issue 1, 2012, Pages 141-153

  Queirós, Odília ^a   Preto, Ana ^b   Pacheco, António ^a   Pinheiro, Céline ^b,c   Azevedo Silva, João ^b   Moreira, Roxana ^a   Pedro, Madalena ^a   Ko, Young H ^d   Pedersen, Peter L ^e   Baltazar, Fátima ^b,c   Casal, Margarida ^b  

^a UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^b UNIVERSITY OF MINHO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d School of Medicine ^*  (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

3 bromopyruvate; Butyrate; Monocarboxylate transporters; Warburg effect

Indexed keywords

ANTINEOPLASTIC AGENT; BROMOPYRUVIC ACID; BUTYRIC ACID; CD147 ANTIGEN; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 4; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CELL STRAIN; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY;

EID: 84858708932     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-012-9418-3     Document Type: Article

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