Computational analyses of a pressurized metered dose inhaler and a new drug-aerosol targeting methodology

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung

Volumn 20, Issue 3, 2007, Pages 294-309

  Kleinstreuer, Clement ^a   Shi, Huawei ^b   Zhe, Zhang ^c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b Turbine Technology International   (United States)

^c North Carolina State University   (United States)

Author keywords

Computer simulation; Controlled air particle stream; Droplet spray formation; Droplet transport deposition; Human upper airways; pMDI performance; Targeted drug aerosol transport deposition

Indexed keywords

CHLOROFLUOROCARBON; FLUORINATED HYDROCARBON; PROPELLANT;

AEROSOL; AIRWAY; ARTICLE; ASTHMA; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; DEVICE; DRUG DELIVERY SYSTEM; HUMAN; INHALATION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MEASUREMENT; METERED DOSE INHALER; PARTICLE SIZE; PREDICTION; PRESSURE; TECHNIQUE; VALIDATION PROCESS;

AEROSOL PROPELLANTS; AEROSOLS; ANTI-ASTHMATIC AGENTS; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; HUMANS; HYDROCARBONS, FLUORINATED; INHALATION SPACERS; METERED DOSE INHALERS; MODELS, BIOLOGICAL; MOTION; PARTICLE SIZE; PRESSURE; REPRODUCIBILITY OF RESULTS; RESPIRATORY SYSTEM;

EID: 34748868940     PISSN: 08942684     EISSN: None     Source Type: Journal    
DOI: 10.1089/jam.2006.0617     Document Type: Article

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