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Volumn 8, Issue 3, 2012, Pages 243-254

FcγRIIB: A modulator of cell activation and humoral tolerance

Author keywords

B cell; humoral tolerance; IgG; inhibitory Fc receptor; innate immune effector cells; IVIg

Indexed keywords

ANTINUCLEAR ANTIBODY; B LYMPHOCYTE RECEPTOR; C REACTIVE PROTEIN; FC RECEPTOR IIB; GENOMIC DNA; IMMUNOGLOBULIN G; INTERLEUKIN 2; T LYMPHOCYTE ANTIGEN;

EID: 84858434212     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/eci.12.5     Document Type: Review
Times cited : (26)

References (117)
  • 1
    • 0036888558 scopus 로고    scopus 로고
    • Fc receptors are major mediators of antibody based inflammation in autoimmunity
    • Hogarth PM. Fc receptors are major mediators of antibody based inflammation in autoimmunity. Curr. Opin. Immunol. 14(6), 798-802 (2002).
    • (2002) Curr. Opin. Immunol. , vol.14 , Issue.6 , pp. 798-802
    • Hogarth, P.M.1
  • 2
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn F, Ravetch JV. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 8(1), 34-47 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.1 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 3
    • 0036676975 scopus 로고    scopus 로고
    • Roles of Fc receptors in autoimmunity
    • Takai T. Roles of Fc receptors in autoimmunity. Nat. Rev. Immunol. 2(8), 580-592 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , Issue.8 , pp. 580-592
    • Takai, T.1
  • 4
    • 34548303252 scopus 로고    scopus 로고
    • FcgammaRIIB as a modulator of autoimmune disease susceptibility
    • Tarasenko T, Dean JA, Bolland S. FcgammaRIIB as a modulator of autoimmune disease susceptibility. Autoimmunity 40(6), 409-417 (2007).
    • (2007) Autoimmunity , vol.40 , Issue.6 , pp. 409-417
    • Tarasenko, T.1    Dean, J.A.2    Bolland, S.3
  • 5
    • 33646167220 scopus 로고    scopus 로고
    • Negative signaling in Fc receptor complexes
    • Daeron M, Lesourne R. Negative signaling in Fc receptor complexes. Adv. Immunol. 89, 39-86 (2006).
    • (2006) Adv. Immunol. , vol.89 , pp. 39-86
    • Daeron, M.1    Lesourne, R.2
  • 6
    • 0035127225 scopus 로고    scopus 로고
    • New functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs
    • Nitschke L, Floyd H, Crocker PR. New functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs. Scand. J. Immunol. 53(3), 227-234 (2001).
    • (2001) Scand. J. Immunol. , vol.53 , Issue.3 , pp. 227-234
    • Nitschke, L.1    Floyd, H.2    Crocker, P.R.3
  • 7
    • 0034613151 scopus 로고    scopus 로고
    • Immune inhibitory receptors
    • Ravetch JV, Lanier LL. Immune inhibitory receptors. Science 290(5489), 84-89 (2000).
    • (2000) Science , vol.290 , Issue.5489 , pp. 84-89
    • Ravetch, J.V.1    Lanier, L.L.2
  • 8
    • 77953760056 scopus 로고    scopus 로고
    • Antibody-mediated modulation of immune responses
    • Nimmerjahn F, Ravetch JV. Antibody-mediated modulation of immune responses. Immunol. Rev. 236, 265-275 (2010).
    • (2010) Immunol. Rev. , vol.236 , pp. 265-275
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 9
    • 49649104429 scopus 로고    scopus 로고
    • Immune regulation: FcgammaRIIB - Regulating the balance between protective and autoreactive immune responses
    • Baerenwaldt A, Nimmerjahn F. Immune regulation: FcgammaRIIB - regulating the balance between protective and autoreactive immune responses. Immunol. Cell. Biol. 86(6), 482-484 (2008).
    • (2008) Immunol. Cell. Biol. , vol.86 , Issue.6 , pp. 482-484
    • Baerenwaldt, A.1    Nimmerjahn, F.2
  • 11
    • 0026698056 scopus 로고
    • Ontogeny and distribution of the murine B cell Fc gamma RII
    • Foy TM, Lynch RG, Waldschmidt TJ. Ontogeny and distribution of the murine B cell Fc gamma RII. J. Immunol. 149(5), 1516-1523 (1992).
    • (1992) J. Immunol. , vol.149 , Issue.5 , pp. 1516-1523
    • Foy, T.M.1    Lynch, R.G.2    Waldschmidt, T.J.3
  • 12
    • 33947575824 scopus 로고    scopus 로고
    • FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis
    • Xiang Z, Cutler AJ, Brownlie RJ et al. FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis. Nat. Immunol. 8(4), 419-429 (2007).
    • (2007) Nat. Immunol. , vol.8 , Issue.4 , pp. 419-429
    • Xiang, Z.1    Cutler, A.J.2    Brownlie, R.J.3
  • 13
    • 0037080203 scopus 로고    scopus 로고
    • The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB
    • Kato I, Takai T, Kudo A. The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB. J. Immunol. 168(2), 629-634 (2002).
    • (2002) J. Immunol. , vol.168 , Issue.2 , pp. 629-634
    • Kato, I.1    Takai, T.2    Kudo, A.3
  • 14
    • 0032531434 scopus 로고    scopus 로고
    • A regulatory role for Fcgamma receptors CD16 and CD32 in the development of murine B cells
    • De Andres B, Mueller AL, Verbeek S, Sandor M, Lynch RG. A regulatory role for Fcgamma receptors CD16 and CD32 in the development of murine B cells. Blood 92(8), 2823-2829 (1998).
    • (1998) Blood , vol.92 , Issue.8 , pp. 2823-2829
    • De Andres, B.1    Mueller, A.L.2    Verbeek, S.3    Sandor, M.4    Lynch, R.G.5
  • 15
    • 81755186999 scopus 로고    scopus 로고
    • Fcgamma receptor IIB (FcgammaRIIB) maintains humoral tolerance in the human immune system in vivo
    • Baerenwaldt A, Lux A, Danzer H et al. Fcgamma receptor IIB (FcgammaRIIB) maintains humoral tolerance in the human immune system in vivo. Proc. Natl Acad. Sci. USA 108(46), 18772-18777 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.46 , pp. 18772-18777
    • Baerenwaldt, A.1    Lux, A.2    Danzer, H.3
  • 16
    • 0036882837 scopus 로고    scopus 로고
    • FcgammaRIIb expression on human germinal center B lymphocytes
    • Macardle PJ, Mardell C, Bailey S et al. FcgammaRIIb expression on human germinal center B lymphocytes. Eur. J. Immunol. 32(12), 3736-3744 (2002).
    • (2002) Eur. J. Immunol. , vol.32 , Issue.12 , pp. 3736-3744
    • MacArdle, P.J.1    Mardell, C.2    Bailey, S.3
  • 17
    • 0037108491 scopus 로고    scopus 로고
    • Transcriptional regulation of Fcgr2b gene by polymorphic promoter region and its contribution to humoral immune responses
    • Xiu Y, Nakamura K, Abe M et al. Transcriptional regulation of Fcgr2b gene by polymorphic promoter region and its contribution to humoral immune responses. J. Immunol. 169(8), 4340-4346 (2002).
    • (2002) J. Immunol. , vol.169 , Issue.8 , pp. 4340-4346
    • Xiu, Y.1    Nakamura, K.2    Abe, M.3
  • 18
    • 33846245118 scopus 로고    scopus 로고
    • FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity
    • Rahman ZS, Alabyev B, Manser T. FcgammaRIIB regulates autoreactive primary antibody-forming cell, but not germinal center B cell, activity. J. Immunol. 178(2), 897-907 (2007).
    • (2007) J. Immunol. , vol.178 , Issue.2 , pp. 897-907
    • Rahman, Z.S.1    Alabyev, B.2    Manser, T.3
  • 19
    • 22544488365 scopus 로고    scopus 로고
    • Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene
    • Rahman ZS, Manser T. Failed up-regulation of the inhibitory IgG Fc receptor Fc gamma RIIB on germinal center B cells in autoimmune-prone mice is not associated with deletion polymorphisms in the promoter region of the Fc gamma RIIB gene. J. Immunol. 175(3), 1440-1449 (2005).
    • (2005) J. Immunol. , vol.175 , Issue.3 , pp. 1440-1449
    • Rahman, Z.S.1    Manser, T.2
  • 20
    • 34250370468 scopus 로고    scopus 로고
    • Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type i interferon response program
    • Dhodapkar KM, Banerjee D, Connolly J et al. Selective blockade of the inhibitory Fcgamma receptor (FcgammaRIIB) in human dendritic cells and monocytes induces a type I interferon response program. J. Exp. Med. 204(6), 1359-1369 (2007).
    • (2007) J. Exp. Med. , vol.204 , Issue.6 , pp. 1359-1369
    • Dhodapkar, K.M.1    Banerjee, D.2    Connolly, J.3
  • 21
    • 14544308857 scopus 로고    scopus 로고
    • Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
    • Dhodapkar KM, Kaufman JL, Ehlers M et al. Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells. Proc. Natl Acad. Sci. USA 102(8), 2910-2915 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.8 , pp. 2910-2915
    • Dhodapkar, K.M.1    Kaufman, J.L.2    Ehlers, M.3
  • 22
    • 0037033448 scopus 로고    scopus 로고
    • Antitumor monoclonal antibodies enhance cross-presentation of Cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells
    • Dhodapkar KM, Krasovsky J, Williamson B, Dhodapkar MV. Antitumor monoclonal antibodies enhance cross-presentation of Cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells. J. Exp. Med. 195(1), 125-133 (2002).
    • (2002) J. Exp. Med. , vol.195 , Issue.1 , pp. 125-133
    • Dhodapkar, K.M.1    Krasovsky, J.2    Williamson, B.3    Dhodapkar, M.V.4
  • 23
  • 24
    • 33748417874 scopus 로고    scopus 로고
    • CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions
    • Devaraj S, Davis B, Simon SI, Jialal I. CRP promotes monocyte-endothelial cell adhesion via Fcgamma receptors in human aortic endothelial cells under static and shear flow conditions. Am. J. Physiol. Heart Circ. Physiol. 1(3), 1170-1176 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.1 , Issue.3 , pp. 1170-1176
    • Devaraj, S.1    Davis, B.2    Simon, S.I.3    Jialal, I.4
  • 25
    • 0034659826 scopus 로고    scopus 로고
    • Fc gamma receptor IIB on follicular dendritic cells regulates the B cell recall response
    • Qin D, Wu J, Vora KA et al. Fc gamma receptor IIB on follicular dendritic cells regulates the B cell recall response. J. Immunol. 164(12), 6268-6275 (2000).
    • (2000) J. Immunol. , vol.164 , Issue.12 , pp. 6268-6275
    • Qin, D.1    Wu, J.2    Vora, K.A.3
  • 26
    • 0021357364 scopus 로고
    • Cross-linking of B lymphocyte Fc gamma receptors and membrane immunoglobulin inhibits anti-immunoglobulin-induced blastogenesis
    • Phillips NE, Parker DC. Cross-linking of B lymphocyte Fc gamma receptors and membrane immunoglobulin inhibits anti-immunoglobulin-induced blastogenesis. J. Immunol. 132(2), 627-632 (1984).
    • (1984) J. Immunol. , vol.132 , Issue.2 , pp. 627-632
    • Phillips, N.E.1    Parker, D.C.2
  • 27
    • 0029835940 scopus 로고    scopus 로고
    • Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB
    • Ono M, Bolland S, Tempst P, Ravetch JV. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. Nature 383(6597), 263-266 (1996).
    • (1996) Nature , vol.383 , Issue.6597 , pp. 263-266
    • Ono, M.1    Bolland, S.2    Tempst, P.3    Ravetch, J.V.4
  • 28
    • 0343307005 scopus 로고    scopus 로고
    • Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling
    • Ono M, Okada H, Bolland S et al. Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling. Cell 90(2), 293-301 (1997).
    • (1997) Cell , vol.90 , Issue.2 , pp. 293-301
    • Ono, M.1    Okada, H.2    Bolland, S.3
  • 30
    • 27444446355 scopus 로고    scopus 로고
    • The B cell inhibitory Fc receptor triggers apoptosis by a novel c-Abl-family kinase dependent pathway
    • Tzeng SJ, Bolland S, Inabe K, Kurosaki T, Pierce SK. The B cell inhibitory Fc receptor triggers apoptosis by a novel c-Abl-family kinase dependent pathway. J. Biol. Chem. 280(42), 35247-35254 (2005).
    • (2005) J. Biol. Chem. , vol.280 , Issue.42 , pp. 35247-35254
    • Tzeng, S.J.1    Bolland, S.2    Inabe, K.3    Kurosaki, T.4    Pierce, S.K.5
  • 31
    • 33749018225 scopus 로고    scopus 로고
    • Competence and competition: The challenge of becoming a long-lived plasma cell
    • Radbruch A, Muehlinghaus G, Luger EO et al. Competence and competition: The challenge of becoming a long-lived plasma cell. Nat. Rev. Immunol. 6(10), 741-750 (2006).
    • (2006) Nat. Rev. Immunol. , vol.6 , Issue.10 , pp. 741-750
    • Radbruch, A.1    Muehlinghaus, G.2    Luger, E.O.3
  • 32
    • 1842663154 scopus 로고    scopus 로고
    • Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death
    • Brauweiler AM, Cambier JC. Autonomous SHIP-dependent FcgammaR signaling in pre-B cells leads to inhibition of cell migration and induction of cell death. Immunol. Lett. 92(1-2), 75-81 (2004).
    • (2004) Immunol. Lett. , vol.92 , Issue.1-2 , pp. 75-81
    • Brauweiler, A.M.1    Cambier, J.C.2
  • 33
    • 54049146662 scopus 로고    scopus 로고
    • Activation of human peripheral IgM+ B cells is transiently inhibited by BCR-independent aggregation of Fc gammaRIIB
    • Fournier EM, Siberil S, Costes A et al. Activation of human peripheral IgM+ B cells is transiently inhibited by BCR-independent aggregation of Fc gammaRIIB. J. Immunol. 181(8), 5350-5359 (2008).
    • (2008) J. Immunol. , vol.181 , Issue.8 , pp. 5350-5359
    • Fournier, E.M.1    Siberil, S.2    Costes, A.3
  • 34
    • 0030031886 scopus 로고    scopus 로고
    • Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice
    • Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV. Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 379(6563), 346-349 (1996).
    • (1996) Nature , vol.379 , Issue.6563 , pp. 346-349
    • Takai, T.1    Ono, M.2    Hikida, M.3    Ohmori, H.4    Ravetch, J.V.5
  • 35
    • 0033695963 scopus 로고    scopus 로고
    • Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis
    • Bolland S, Ravetch JV. Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis. Immunity 13(2), 277-228 (2000).
    • (2000) Immunity , vol.13 , Issue.2 , pp. 277-228
    • Bolland, S.1    Ravetch, J.V.2
  • 36
    • 0037029604 scopus 로고    scopus 로고
    • Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice
    • Bolland S, Yim YS, Tus K, Wakeland EK, Ravetch JV. Genetic modifiers of systemic lupus erythematosus in FcgammaRIIB(-/-) mice. J. Exp. Med. 195(9), 1167-1174 (2002).
    • (2002) J. Exp. Med. , vol.195 , Issue.9 , pp. 1167-1174
    • Bolland, S.1    Yim, Y.S.2    Tus, K.3    Wakeland, E.K.4    Ravetch, J.V.5
  • 37
    • 0037730377 scopus 로고    scopus 로고
    • FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease
    • Yajima K, Nakamura A, Sugahara A, Takai T. FcgammaRIIB deficiency with Fas mutation is sufficient for the development of systemic autoimmune disease. Eur. J. Immunol. 33(4), 1020-1029 (2003).
    • (2003) Eur. J. Immunol. , vol.33 , Issue.4 , pp. 1020-1029
    • Yajima, K.1    Nakamura, A.2    Sugahara, A.3    Takai, T.4
  • 39
    • 33745617886 scopus 로고    scopus 로고
    • A TLR7 translocation accelerates systemic autoimmunity in murine lupus
    • Subramanian S, Tus K, Li QZ et al. A TLR7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl Acad. Sci. USA 103(26), 9970-9975 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.26 , pp. 9970-9975
    • Subramanian, S.1    Tus, K.2    Li, Q.Z.3
  • 40
    • 12344273445 scopus 로고    scopus 로고
    • The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells
    • Fukuyama H, Nimmerjahn F, Ravetch JV. The inhibitory Fcgamma receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells. Nat. Immunol. 6(1), 99-106 (2005).
    • (2005) Nat. Immunol. , vol.6 , Issue.1 , pp. 99-106
    • Fukuyama, H.1    Nimmerjahn, F.2    Ravetch, J.V.3
  • 41
    • 34047095922 scopus 로고    scopus 로고
    • Follicular exclusion of autoreactive B cells requires FcgammaRIIb
    • Paul E, Nelde A, Verschoor A, Carroll MC. Follicular exclusion of autoreactive B cells requires FcgammaRIIb. Int. Immunol. 19(4), 365-373 (2007).
    • (2007) Int. Immunol. , vol.19 , Issue.4 , pp. 365-373
    • Paul, E.1    Nelde, A.2    Verschoor, A.3    Carroll, M.C.4
  • 42
    • 78649404559 scopus 로고    scopus 로고
    • Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice
    • Tiller T, Kofer J, Kreschel C et al. Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice. J. Exp. Med. 207(12), 2767-2778 (2010).
    • (2010) J. Exp. Med. , vol.207 , Issue.12 , pp. 2767-2778
    • Tiller, T.1    Kofer, J.2    Kreschel, C.3
  • 43
    • 45949111444 scopus 로고    scopus 로고
    • FcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ mice
    • Mcgaha TL, Karlsson MC, Ravetch JV. FcgammaRIIB deficiency leads to autoimmunity and a defective response to apoptosis in Mrl-MpJ mice. J. Immunol. 180(8), 5670-5679 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.8 , pp. 5670-5679
    • McGaha, T.L.1    Karlsson, M.C.2    Ravetch, J.V.3
  • 44
    • 0034102982 scopus 로고    scopus 로고
    • Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility
    • Jiang Y, Hirose S, Abe M et al. Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility. Immunogenetics 51(6), 429-435 (2000).
    • (2000) Immunogenetics , vol.51 , Issue.6 , pp. 429-435
    • Jiang, Y.1    Hirose, S.2    Abe, M.3
  • 45
    • 0032840072 scopus 로고    scopus 로고
    • Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus
    • Jiang Y, Hirose S, Sanokawa-Akakura R et al. Genetically determined aberrant down-regulation of FcgammaRIIB1 in germinal center B cells associated with hyper-IgG and IgG autoantibodies in murine systemic lupus erythematosus. Int. Immunol. 11(10), 1685-1691 (1999).
    • (1999) Int. Immunol. , vol.11 , Issue.10 , pp. 1685-1691
    • Jiang, Y.1    Hirose, S.2    Sanokawa-Akakura, R.3
  • 46
    • 0034708252 scopus 로고    scopus 로고
    • Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII
    • Pritchard NR, Cutler AJ, Uribe S, Chadban SJ, Morley BJ, Smith KG. Autoimmune-prone mice share a promoter haplotype associated with reduced expression and function of the Fc receptor FcgammaRII. Curr. Biol. 10(4), 227-230 (2000).
    • (2000) Curr. Biol. , vol.10 , Issue.4 , pp. 227-230
    • Pritchard, N.R.1    Cutler, A.J.2    Uribe, S.3    Chadban, S.J.4    Morley, B.J.5    Smith, K.G.6
  • 47
    • 12844251399 scopus 로고    scopus 로고
    • Restoration of tolerance in lupus by targeted inhibitory receptor expression
    • Mcgaha TL, Sorrentino B, Ravetch JV. Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science 307(5709), 590-593 (2005).
    • (2005) Science , vol.307 , Issue.5709 , pp. 590-593
    • McGaha, T.L.1    Sorrentino, B.2    Ravetch, J.V.3
  • 48
    • 42249096407 scopus 로고    scopus 로고
    • Distinct cell-specif.ific control of autoimmunity and infection by FcgammaRIIb
    • Brownlie RJ, Lawlor KE, Niederer HA et al. Distinct cell-specif.ific control of autoimmunity and infection by FcgammaRIIb. J. Exp. Med. 205(4), 883-895 (2008).
    • (2008) J. Exp. Med. , vol.205 , Issue.4 , pp. 883-895
    • Brownlie, R.J.1    Lawlor, K.E.2    Niederer, H.A.3
  • 49
    • 33746210268 scopus 로고    scopus 로고
    • Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus
    • Lin Q, Xiu Y, Jiang Y et al. Genetic dissection of the effects of stimulatory and inhibitory IgG Fc receptors on murine lupus. J. Immunol. 177(3), 1646-1654 (2006).
    • (2006) J. Immunol. , vol.177 , Issue.3 , pp. 1646-1654
    • Lin, Q.1    Xiu, Y.2    Jiang, Y.3
  • 50
    • 79955019213 scopus 로고    scopus 로고
    • Antibody-mediated coengagement of FcgammaRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus
    • Horton HM, Chu SY, Ortiz EC et al. Antibody-mediated coengagement of FcgammaRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus. J. Immunol. 186(7), 4223-4233 (2011).
    • (2011) J. Immunol. , vol.186 , Issue.7 , pp. 4223-4233
    • Horton, H.M.1    Chu, S.Y.2    Ortiz, E.C.3
  • 51
    • 77954232707 scopus 로고    scopus 로고
    • Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold
    • Veri MC, Burke S, Huang L et al. Therapeutic control of B cell activation via recruitment of Fcgamma receptor IIb (CD32B) inhibitory function with a novel bispecific antibody scaffold. Arthritis Rheum. 62(7), 1933-1943 (2010).
    • (2010) Arthritis Rheum. , vol.62 , Issue.7 , pp. 1933-1943
    • Veri, M.C.1    Burke, S.2    Huang, L.3
  • 52
    • 80051627971 scopus 로고    scopus 로고
    • The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility
    • Boross P, Arandhara VL, Martin-Ramirez J et al. The inhibiting Fc receptor for IgG, FcgammaRIIB, is a modifier of autoimmune susceptibility. J. Immunol. 187(3), 1304-1313 (2011).
    • (2011) J. Immunol. , vol.187 , Issue.3 , pp. 1304-1313
    • Boross, P.1    Arandhara, V.L.2    Martin-Ramirez, J.3
  • 53
    • 19344369383 scopus 로고    scopus 로고
    • Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice
    • Bygrave AE, Rose KL, Cortes-Hernandez J et al. Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice. PLoS Biol. 2(8), E243 (2004).
    • (2004) PLoS Biol. , vol.2 , Issue.8
    • Bygrave, A.E.1    Rose, K.L.2    Cortes-Hernandez, J.3
  • 54
    • 10344252778 scopus 로고    scopus 로고
    • Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus
    • Wandstrat AE, Nguyen C, Limaye N et al. Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus. Immunity 21(6), 769-780 (2004).
    • (2004) Immunity , vol.21 , Issue.6 , pp. 769-780
    • Wandstrat, A.E.1    Nguyen, C.2    Limaye, N.3
  • 55
    • 0033059667 scopus 로고    scopus 로고
    • Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity
    • Bickerstaff MC, Botto M, Hutchinson WL et al. Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat. Med. 5(6), 694-697 (1999).
    • (1999) Nat. Med. , vol.5 , Issue.6 , pp. 694-697
    • Bickerstaff, M.C.1    Botto, M.2    Hutchinson, W.L.3
  • 57
    • 0033583479 scopus 로고    scopus 로고
    • Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
    • O'keefe TL, Williams GT, Batista FD, Neuberger MS. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies. J. Exp. Med. 189(8), 1307-1313 (1999).
    • (1999) J. Exp. Med. , vol.189 , Issue.8 , pp. 1307-1313
    • O'Keefe, T.L.1    Williams, G.T.2    Batista, F.D.3    Neuberger, M.S.4
  • 59
    • 80054020840 scopus 로고    scopus 로고
    • Peripheral education of the immune system by colonic commensal microbiota
    • Lathrop SK, Bloom SM, Rao SM et al. Peripheral education of the immune system by colonic commensal microbiota. Nature 478(7368), 250-254 (2011).
    • (2011) Nature , vol.478 , Issue.7368 , pp. 250-254
    • Lathrop, S.K.1    Bloom, S.M.2    Rao, S.M.3
  • 60
    • 79960983258 scopus 로고    scopus 로고
    • Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
    • Kriegel MA, Sefik E, Hill JA, Wu HJ, Benoist C, Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc. Natl Acad. Sci. USA 108(28), 11548-11553 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.28 , pp. 11548-11553
    • Kriegel, M.A.1    Sefik, E.2    Hill, J.A.3    Wu, H.J.4    Benoist, C.5    Mathis, D.6
  • 61
    • 79953160962 scopus 로고    scopus 로고
    • Commensal flora and the regulation of inflammatory and autoimmune responses
    • Kranich J, Maslowski KM, Mackay CR. Commensal flora and the regulation of inflammatory and autoimmune responses. Semin. Immunol. 23(2), 139-145 (2011).
    • (2011) Semin. Immunol. , vol.23 , Issue.2 , pp. 139-145
    • Kranich, J.1    Maslowski, K.M.2    MacKay, C.R.3
  • 62
    • 29144469468 scopus 로고    scopus 로고
    • Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-fcgr2b-/-Pdcd1-/- mice
    • Okazaki T, Otaka Y, Wang J et al. Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-fcgr2b-/-Pdcd1-/- mice. J. Exp. Med. 202(12), 1643-1648 (2005).
    • (2005) J. Exp. Med. , vol.202 , Issue.12 , pp. 1643-1648
    • Okazaki, T.1    Otaka, Y.2    Wang, J.3
  • 63
    • 22344452484 scopus 로고    scopus 로고
    • Modulation of the immune response in pristane-induced lupus by expression of activation and inhibitory Fc receptors
    • Clynes R, Calvani N, Croker BP, Richards HB. Modulation of the immune response in pristane-induced lupus by expression of activation and inhibitory Fc receptors. Clin. Exp. Immunol. 141(2), 230-237 (2005).
    • (2005) Clin. Exp. Immunol. , vol.141 , Issue.2 , pp. 230-237
    • Clynes, R.1    Calvani, N.2    Croker, B.P.3    Richards, H.B.4
  • 64
    • 0037725010 scopus 로고    scopus 로고
    • Deregulation of peripheral B-cell development in enhanced severity of collagen-induced arthritis in FcgammaRIIB-deficient mice
    • Nakamura A, Nukiwa T, Takai T. Deregulation of peripheral B-cell development in enhanced severity of collagen-induced arthritis in FcgammaRIIB-deficient mice. J. Autoimmun. 20(3), 227-236 (2003).
    • (2003) J. Autoimmun. , vol.20 , Issue.3 , pp. 227-236
    • Nakamura, A.1    Nukiwa, T.2    Takai, T.3
  • 65
    • 0034610854 scopus 로고    scopus 로고
    • Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: A novel murine model for autoimmune glomerular basement membrane disease
    • Nakamura A, Yuasa T, Ujike A et al. Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: A novel murine model for autoimmune glomerular basement membrane disease. J. Exp. Med. 191(5), 899-906 (2000).
    • (2000) J. Exp. Med. , vol.191 , Issue.5 , pp. 899-906
    • Nakamura, A.1    Yuasa, T.2    Ujike, A.3
  • 66
    • 79551625903 scopus 로고    scopus 로고
    • Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice
    • Waisberg M, Tarasenko T, Vickers BK et al. Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice. Proc. Natl Acad. Sci. USA 108(3), 1122-1127 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.3 , pp. 1122-1127
    • Waisberg, M.1    Tarasenko, T.2    Vickers, B.K.3
  • 67
    • 34249736602 scopus 로고    scopus 로고
    • Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria
    • Clatworthy MR, Willcocks L, Urban B et al. Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria. Proc. Natl Acad. Sci. USA 104(17), 7169-7174 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.17 , pp. 7169-7174
    • Clatworthy, M.R.1    Willcocks, L.2    Urban, B.3
  • 68
    • 77951572775 scopus 로고    scopus 로고
    • A defunctioning polymorphism in fcgr2b is associated with protection against malaria but susceptibility to systemic lupus erythematosus
    • Willcocks LC, Carr EJ, Niederer HA et al. A defunctioning polymorphism in fcgr2b is associated with protection against malaria but susceptibility to systemic lupus erythematosus. Proc. Natl Acad. Sci. USA 107(17), 7881-7885 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.17 , pp. 7881-7885
    • Willcocks, L.C.1    Carr, E.J.2    Niederer, H.A.3
  • 69
    • 0037565445 scopus 로고    scopus 로고
    • Dendritic cell function in vivo during the steady state: A role in peripheral tolerance
    • Steinman RM, Hawiger D, Liu K et al. Dendritic cell function in vivo during the steady state: A role in peripheral tolerance. Ann. NY Acad. Sci. 987, 15-25 (2003).
    • (2003) Ann. NY Acad. Sci. , vol.987 , pp. 15-25
    • Steinman, R.M.1    Hawiger, D.2    Liu, K.3
  • 70
    • 33846636409 scopus 로고    scopus 로고
    • Differential antigen processing by dendritic cell subsets in vivo
    • Dudziak D, Kamphorst AO, Heidkamp GF et al. Differential antigen processing by dendritic cell subsets in vivo. Science 315(5808), 107-111 (2007).
    • (2007) Science , vol.315 , Issue.5808 , pp. 107-111
    • Dudziak, D.1    Kamphorst, A.O.2    Heidkamp, G.F.3
  • 71
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194(6), 769-779 (2001).
    • (2001) J. Exp. Med. , vol.194 , Issue.6 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3
  • 72
    • 58149177778 scopus 로고    scopus 로고
    • CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells
    • Yamazaki S, Dudziak D, Heidkamp GF et al. CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells. J. Immunol. 181(10), 6923-6933 (2008).
    • (2008) J. Immunol. , vol.181 , Issue.10 , pp. 6923-6933
    • Yamazaki, S.1    Dudziak, D.2    Heidkamp, G.F.3
  • 73
    • 0036307752 scopus 로고    scopus 로고
    • Immune complex-mediated antigen presentation induces tumor immunity
    • Rafiq K, Bergtold A, Clynes R. Immune complex-mediated antigen presentation induces tumor immunity. J. Clin. Invest. 110(1), 71-79 (2002).
    • (2002) J. Clin. Invest. , vol.110 , Issue.1 , pp. 71-79
    • Rafiq, K.1    Bergtold, A.2    Clynes, R.3
  • 74
    • 0033579698 scopus 로고    scopus 로고
    • Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization
    • Regnault A, Lankar D, Lacabanne V et al. Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization. J. Exp. Med. 189(2), 371-380 (1999).
    • (1999) J. Exp. Med. , vol.189 , Issue.2 , pp. 371-380
    • Regnault, A.1    Lankar, D.2    Lacabanne, V.3
  • 75
    • 18144365892 scopus 로고    scopus 로고
    • Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells
    • Groh V, Li YQ, Cioca D et al. Efficient cross-priming of tumor antigen-specific T cells by dendritic cells sensitized with diverse anti-MICA opsonized tumor cells. Proc. Natl Acad. Sci. USA 102(18), 6461-6466 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.18 , pp. 6461-6466
    • Groh, V.1    Li, Y.Q.2    Cioca, D.3
  • 76
    • 34248213007 scopus 로고    scopus 로고
    • Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance
    • Harbers SO, Crocker A, Catalano G et al. Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J. Clin. Invest. 117(5), 1361-1369 (2007).
    • (2007) J. Clin. Invest. , vol.117 , Issue.5 , pp. 1361-1369
    • Harbers, S.O.1    Crocker, A.2    Catalano, G.3
  • 77
    • 0037124367 scopus 로고    scopus 로고
    • Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells
    • Kalergis AM, Ravetch JV. Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells. J. Exp. Med. 195(12), 1653-1659 (2002).
    • (2002) J. Exp. Med. , vol.195 , Issue.12 , pp. 1653-1659
    • Kalergis, A.M.1    Ravetch, J.V.2
  • 78
    • 34248198895 scopus 로고    scopus 로고
    • Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses
    • Desai DD, Harbers SO, Flores M et al. Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses. J. Immunol. 178(10), 6217-6226 (2007).
    • (2007) J. Immunol. , vol.178 , Issue.10 , pp. 6217-6226
    • Desai, D.D.1    Harbers, S.O.2    Flores, M.3
  • 79
    • 73349104434 scopus 로고    scopus 로고
    • Dominant expression of the inhibitory FcgammaRIIB prevents antigen presentation by murine plasmacytoid dendritic cells
    • Flores M, Desai DD, Downie M et al. Dominant expression of the inhibitory FcgammaRIIB prevents antigen presentation by murine plasmacytoid dendritic cells. J. Immunol. 183(11), 7129-7139 (2009).
    • (2009) J. Immunol. , vol.183 , Issue.11 , pp. 7129-7139
    • Flores, M.1    Desai, D.D.2    Downie, M.3
  • 80
    • 0032145432 scopus 로고    scopus 로고
    • Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response
    • Wykes M, Pombo A, Jenkins C, Macpherson GG. Dendritic cells interact directly with naive B lymphocytes to transfer antigen and initiate class switching in a primary T-dependent response. J. Immunol. 161(3), 1313-1319 (1998).
    • (1998) J. Immunol. , vol.161 , Issue.3 , pp. 1313-1319
    • Wykes, M.1    Pombo, A.2    Jenkins, C.3    MacPherson, G.G.4
  • 81
    • 0032811453 scopus 로고    scopus 로고
    • Dendritic cells directly modulate B cell growth and differentiation
    • Dubois B, Bridon JM, Fayette J et al. Dendritic cells directly modulate B cell growth and differentiation. J. Leukoc. Biol. 66(2), 224-230 (1999).
    • (1999) J. Leukoc. Biol. , vol.66 , Issue.2 , pp. 224-230
    • Dubois, B.1    Bridon, J.M.2    Fayette, J.3
  • 82
    • 0344258320 scopus 로고    scopus 로고
    • Toward a role of dendritic cells in the germinal center reaction: Triggering of B cell proliferation and isotype switching
    • Dubois B, Barthelemy C, Durand I, Liu YJ, Caux C, Briere F. Toward a role of dendritic cells in the germinal center reaction: Triggering of B cell proliferation and isotype switching. J. Immunol. 162(6), 3428-3436 (1999).
    • (1999) J. Immunol. , vol.162 , Issue.6 , pp. 3428-3436
    • Dubois, B.1    Barthelemy, C.2    Durand, I.3    Liu, Y.J.4    Caux, C.5    Briere, F.6
  • 83
    • 0034651921 scopus 로고    scopus 로고
    • Human interdigitating dendritic cells induce isotype switching and IL-13-dependent IgM production in CD40-activated naive B cells
    • Johansson B, Ingvarsson S, Bjorck P, Borrebaeck CA. Human interdigitating dendritic cells induce isotype switching and IL-13-dependent IgM production in CD40-activated naive B cells. J. Immunol. 164(4), 1847-1854 (2000).
    • (2000) J. Immunol. , vol.164 , Issue.4 , pp. 1847-1854
    • Johansson, B.1    Ingvarsson, S.2    Bjorck, P.3    Borrebaeck, C.A.4
  • 84
    • 27744576801 scopus 로고    scopus 로고
    • Cell surface recycling of internalized antigen permits dendritic cell priming of B cells
    • Bergtold A, Desai DD, Gavhane A, Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity 23(5), 503-514 (2005).
    • (2005) Immunity , vol.23 , Issue.5 , pp. 503-514
    • Bergtold, A.1    Desai, D.D.2    Gavhane, A.3    Clynes, R.4
  • 85
    • 63849187507 scopus 로고    scopus 로고
    • Impaired inhibitory Fc gamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy
    • Tackenberg B, Jelcic I, Baerenwaldt A et al. Impaired inhibitory Fc gamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy. Proc. Natl Acad. Sci. USA 106(12), 4788-4792 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.12 , pp. 4788-4792
    • Tackenberg, B.1    Jelcic, I.2    Baerenwaldt, A.3
  • 86
    • 77956182458 scopus 로고    scopus 로고
    • Mechanisms of IVIG efficacy in chronic inflammatory demyelinating polyneuropathy
    • Tackenberg B, Nimmerjahn F, Lunemann JD. Mechanisms of IVIG efficacy in chronic inflammatory demyelinating polyneuropathy. J. Clin. Immunol. 30 Suppl 1. 65-69 (2010).
    • (2010) J. Clin. Immunol. , vol.30 , Issue.SUPPL. 1 , pp. 65-69
    • Tackenberg, B.1    Nimmerjahn, F.2    Lunemann, J.D.3
  • 87
    • 33748467673 scopus 로고    scopus 로고
    • Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE
    • Mackay M, Stanevsky A, Wang T et al. Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE. J. Exp. Med. 203(9), 2157-2164 (2006).
    • (2006) J. Exp. Med. , vol.203 , Issue.9 , pp. 2157-2164
    • MacKay, M.1    Stanevsky, A.2    Wang, T.3
  • 88
    • 33847375266 scopus 로고    scopus 로고
    • Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus
    • Su K, Yang H, Li X et al. Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J. Immunol. 178(5), 3272-3280 (2007).
    • (2007) J. Immunol. , vol.178 , Issue.5 , pp. 3272-3280
    • Su, K.1    Yang, H.2    Li, X.3
  • 89
    • 26944456633 scopus 로고    scopus 로고
    • Decreased transcription of the human fcgr2b gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus
    • Blank MC, Stefanescu RN, Masuda E et al. Decreased transcription of the human fcgr2b gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus. Hum. Genet. 117(2-3), 220-227 (2005).
    • (2005) Hum. Genet. , vol.117 , Issue.2-3 , pp. 220-227
    • Blank, M.C.1    Stefanescu, R.N.2    Masuda, E.3
  • 90
    • 2442679050 scopus 로고    scopus 로고
    • A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity II Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function
    • Su K, Li X, Edberg JC, Wu J, Ferguson P, Kimberly RP. A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function. J. Immunol. 172(11), 7192-7199 (2004).
    • (2004) J. Immunol. , vol.172 , Issue.11 , pp. 7192-7199
    • Su, K.1    Li, X.2    Edberg, J.C.3    Wu, J.4    Ferguson, P.5    Kimberly, R.P.6
  • 91
    • 2442710233 scopus 로고    scopus 로고
    • A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity i regulatory fcgr2b polymorphisms and their association with systemic lupus erythematosus
    • Su K, Wu J, Edberg JC et al. A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory fcgr2b polymorphisms and their association with systemic lupus erythematosus. J. Immunol. 172(11), 7186-7191 (2004).
    • (2004) J. Immunol. , Issue.172 , pp. 7186-7191
    • Su, K.1    Wu, J.2    Edberg, J.C.3
  • 92
    • 0035983742 scopus 로고    scopus 로고
    • Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: Contribution of fcgr2b to genetic susceptibility
    • Kyogoku C, Dijstelbloem HM, Tsuchiya N et al. Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: Contribution of fcgr2b to genetic susceptibility. Arthritis Rheum. 46(5), 1242-1254 (2002).
    • (2002) Arthritis Rheum. , vol.46 , Issue.5 , pp. 1242-1254
    • Kyogoku, C.1    Dijstelbloem, H.M.2    Tsuchiya, N.3
  • 93
    • 0038191047 scopus 로고    scopus 로고
    • Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais
    • Siriboonrit U, Tsuchiya N, Sirikong M et al. Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais. Tissue Antigens 61(5), 374-383 (2003).
    • (2003) Tissue Antigens , vol.61 , Issue.5 , pp. 374-383
    • Siriboonrit, U.1    Tsuchiya, N.2    Sirikong, M.3
  • 94
    • 1642521645 scopus 로고    scopus 로고
    • Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: A common susceptibility gene in the Asian populations
    • Chu ZT, Tsuchiya N, Kyogoku C et al. Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: A common susceptibility gene in the Asian populations. Tissue Antigens 63(1), 21-27 (2004).
    • (2004) Tissue Antigens , vol.63 , Issue.1 , pp. 21-27
    • Chu, Z.T.1    Tsuchiya, N.2    Kyogoku, C.3
  • 95
    • 77955029498 scopus 로고    scopus 로고
    • Copy number, linkage disequilibrium and disease association in the fcgr locus
    • Niederer HA, Willcocks LC, Rayner TF et al. Copy number, linkage disequilibrium and disease association in the fcgr locus. Hum. Mol. Genet. 19(16), 3282-3294 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , Issue.16 , pp. 3282-3294
    • Niederer, H.A.1    Willcocks, L.C.2    Rayner, T.F.3
  • 96
    • 27144549658 scopus 로고    scopus 로고
    • Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts
    • Floto RA, Clatworthy MR, Heilbronn KR et al. Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. Nat. Med. 11(10), 1056-1058 (2005).
    • (2005) Nat. Med. , vol.11 , Issue.10 , pp. 1056-1058
    • Floto, R.A.1    Clatworthy, M.R.2    Heilbronn, K.R.3
  • 97
    • 26444593959 scopus 로고    scopus 로고
    • FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling
    • Kono H, Kyogoku C, Suzuki T et al. FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling. Hum. Mol. Genet. 14(19), 2881-2892 (2005).
    • (2005) Hum. Mol. Genet. , vol.14 , Issue.19 , pp. 2881-2892
    • Kono, H.1    Kyogoku, C.2    Suzuki, T.3
  • 98
    • 77951610700 scopus 로고    scopus 로고
    • FcgammaRIIB in autoimmunity and infection: Evolutionary and therapeutic implications
    • Smith KG, Clatworthy MR. FcgammaRIIB in autoimmunity and infection: Evolutionary and therapeutic implications. Nat. Rev. Immunol. 10(5), 328-343 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , Issue.5 , pp. 328-343
    • Smith, K.G.1    Clatworthy, M.R.2
  • 99
    • 0242579484 scopus 로고    scopus 로고
    • A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling
    • Li X, Wu J, Carter RH et al. A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum. 48(11), 3242-3252 (2003).
    • (2003) Arthritis Rheum. , vol.48 , Issue.11 , pp. 3242-3252
    • Li, X.1    Wu, J.2    Carter, R.H.3
  • 100
    • 67651102866 scopus 로고    scopus 로고
    • Humanized mice for modeling human infectious disease: Challenges, progress, and outlook
    • Legrand N, Ploss A, Balling R et al. Humanized mice for modeling human infectious disease: Challenges, progress, and outlook. Cell Host Microbe 6(1), 5-9 (2009).
    • (2009) Cell Host Microbe , vol.6 , Issue.1 , pp. 5-9
    • Legrand, N.1    Ploss, A.2    Balling, R.3
  • 102
    • 34249006296 scopus 로고    scopus 로고
    • Intravenous immunoglobulin: An update on the clinical use and mechanisms of action
    • Negi VS, Elluru S, Siberil S et al. Intravenous immunoglobulin: An update on the clinical use and mechanisms of action. J. Clin. Immunol. 27(3), 233-245 (2007).
    • (2007) J. Clin. Immunol. , vol.27 , Issue.3 , pp. 233-245
    • Negi, V.S.1    Elluru, S.2    Siberil, S.3
  • 103
    • 67849121520 scopus 로고    scopus 로고
    • New insight into the mechanism of action of IVIg: The role of dendritic cells
    • Crow AR, Brinc D, Lazarus AH. New insight into the mechanism of action of IVIg: The role of dendritic cells. J. Thromb. Haemost. 7(Suppl 1.), 245-248 (2009).
    • (2009) J. Thromb. Haemost. , vol.7 , Issue.SUPPL. 1 , pp. 245-248
    • Crow, A.R.1    Brinc, D.2    Lazarus, A.H.3
  • 104
    • 42649089750 scopus 로고    scopus 로고
    • Anti-inflammatory actions of intravenous immunoglobulin
    • Nimmerjahn F, Ravetch JV. Anti-inflammatory actions of intravenous immunoglobulin. Annu. Rev. Immunol. 26, 513-533 (2008).
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 513-533
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 105
    • 0037399064 scopus 로고    scopus 로고
    • Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease
    • Bruhns P, Samuelsson A, Pollard JW, Ravetch JV. Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity 18(4), 573-581 (2003).
    • (2003) Immunity , vol.18 , Issue.4 , pp. 573-581
    • Bruhns, P.1    Samuelsson, A.2    Pollard, J.W.3    Ravetch, J.V.4
  • 106
    • 33645080442 scopus 로고    scopus 로고
    • Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors
    • Kaneko Y, Nimmerjahn F, Madaio MP, Ravetch JV. Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors. J. Exp. Med. 203(3), 789-797 (2006).
    • (2006) J. Exp. Med. , vol.203 , Issue.3 , pp. 789-797
    • Kaneko, Y.1    Nimmerjahn, F.2    Madaio, M.P.3    Ravetch, J.V.4
  • 107
    • 33746888249 scopus 로고    scopus 로고
    • Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
    • Kaneko Y, Nimmerjahn F, Ravetch JV. Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 313(5787), 670-673 (2006).
    • (2006) Science , vol.313 , Issue.5787 , pp. 670-673
    • Kaneko, Y.1    Nimmerjahn, F.2    Ravetch, J.V.3
  • 108
    • 0035910392 scopus 로고    scopus 로고
    • Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor
    • Samuelsson A, Towers TL, Ravetch JV. Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor. Science 291(5503), 484-486 (2001).
    • (2001) Science , vol.291 , Issue.5503 , pp. 484-486
    • Samuelsson, A.1    Towers, T.L.2    Ravetch, J.V.3
  • 109
    • 0038494827 scopus 로고    scopus 로고
    • IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1i SHP-1, and Btk activity
    • Crow AR, Song S, Freedman J et al. IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity. Blood 102(2), 558-560 (2003).
    • (2003) Blood , vol.102 , Issue.2 , pp. 558-560
    • Crow, A.R.1    Song, S.2    Freedman, J.3
  • 110
    • 79960046406 scopus 로고    scopus 로고
    • Intravenous gammaglobulin suppresses inflammation through a novel T(h)2 pathway
    • Anthony RM, Kobayashi T, Wermeling F, Ravetch JV. Intravenous gammaglobulin suppresses inflammation through a novel T(h)2 pathway. Nature 475(7354), 110-113 (2011).
    • (2011) Nature , vol.475 , Issue.7354 , pp. 110-113
    • Anthony, R.M.1    Kobayashi, T.2    Wermeling, F.3    Ravetch, J.V.4
  • 111
    • 33751253486 scopus 로고    scopus 로고
    • Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality
    • Scallon BJ, Tam SH, Mccarthy SG, Cai AN, Raju TS. Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality. Mol. Immunol. 44(7), 1524-1534 (2007).
    • (2007) Mol. Immunol. , vol.44 , Issue.7 , pp. 1524-1534
    • Scallon, B.J.1    Tam, S.H.2    McCarthy, S.G.3    Cai, A.N.4    Raju, T.S.5
  • 112
    • 58149378347 scopus 로고    scopus 로고
    • Identification of a receptor required for the anti-inflammatory activity of IVIG
    • Anthony RM, Wermeling F, Karlsson MC, Ravetch JV. Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc. Natl Acad. Sci. USA 105(50), 19571-19578 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.50 , pp. 19571-19578
    • Anthony, R.M.1    Wermeling, F.2    Karlsson, M.C.3    Ravetch, J.V.4
  • 114
    • 80051885494 scopus 로고    scopus 로고
    • Inhibitory Fcgamma receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies
    • Li F, Ravetch JV. Inhibitory Fcgamma receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies. Science 333(6045), 1030-1034 (2011).
    • (2011) Science , vol.333 , Issue.6045 , pp. 1030-1034
    • Li, F.1    Ravetch, J.V.2
  • 115
    • 78651466506 scopus 로고    scopus 로고
    • An Fcgamma receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells
    • Wilson NS, Yang B, Yang A et al. An Fcgamma receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells. Cancer Cell 19(1), 101-113 (2011).
    • (2011) Cancer Cell , vol.19 , Issue.1 , pp. 101-113
    • Wilson, N.S.1    Yang, B.2    Yang, A.3
  • 116
    • 80051925907 scopus 로고    scopus 로고
    • Interaction with FcgammaRIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody
    • White AL, Chan HT, Roghanian A et al. Interaction with FcgammaRIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody. J. Immunol. 187(4), 1754-1763 (2011).
    • (2011) J. Immunol. , vol.187 , Issue.4 , pp. 1754-1763
    • White, A.L.1    Chan, H.T.2    Roghanian, A.3
  • 117
    • 0038446861 scopus 로고    scopus 로고
    • Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: Implications for agonistic antibody-based therapeutics
    • Xu Y, Szalai AJ, Zhou T et al. Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: Implications for agonistic antibody-based therapeutics. J. Immunol. 171(2), 562-568 (2003).
    • (2003) J. Immunol. , vol.171 , Issue.2 , pp. 562-568
    • Xu, Y.1    Szalai, A.J.2    Zhou, T.3


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