New functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs

Scandinavian Journal of Immunology

Volumn 53, Issue 3, 2001, Pages 227-234

  Nitschke, L ^a   Floyd, H ^b   Crocker, P R ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD22 ANTIGEN; COMPLEMENTARY DNA; SIALIC ACID;

ANIMAL CELL; B LYMPHOCYTE; BINDING AFFINITY; BINDING SITE; CELL ADHESION; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; IMMUNE SYSTEM; MACROPHAGE; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD22; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTES; BINDING SITES; BONE MARROW CELLS; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL MOVEMENT; HUMANS; LECTINS; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; N-ACETYLNEURAMINIC ACID; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION;

EID: 0035127225     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00868.x     Document Type: Review

References (60)

1. Sialic acids in molecular and cellular interactions
2. Properties and distribution of a lectin-like hemagglutinin differentially expressed by murine stromal tissue macrophages
3. The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells
4. Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains
5. Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily
6. Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules
7. Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33
8. OB-BP1/Siglec-6, a leptin- and sialic acid-binding protein of the immunoglobulin superfamily
9. Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes
10. Siglec-7: A sialic acid-binding lectin of the immunoglobulin superfamily
11. Identification and molecular cloning of p75/AIRM, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells
12. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily
13. Siglec-9. A novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood Leukocyts
14. Cloning characterization phylogenetic analysis of Siglec-9, a new member of the CD33-related group of siglecs
15. Mouse macrophage hemagglutinin (sheep erythrocyte receptor) with specificity for sialylated glycoconjugates characterized by a monoclonal antibody
16. Macrophage-tumour cell interactions; identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin
17. Regulation of a murine macrophage haemagglutinin (sheep erythrocyte receptor) by a species-restricted serum factor
18. CD22 associates with protein tyrosine phosphatase 1C. Syk. and phospholipase C-gamma (1) upon B cell activation
19. Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations
20. CD22-mediated cell adhesion to cytokine-activated human endothelial cells. Positive and negative regulation by alpha 2-6-sialylation of cellular glycoproteins
21. The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes
22. New aspects of siglec binding specificities, including the significance of fucosylation and of the sialyl-Tn epitope. Sialic acid-binding immunoglobulin superfamily lectins
23. Myelination in the absence of myelin-associated glycoprotein
24. Crucial role for the myelin-associated glycoprotein in the maintenance of axonmyelin integrity
25. The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases. SHP-1 and SHP-2
26. The sialoadhesin CD33 is a myeloid-specific inhibitory receptor
27. Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2
28. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
29. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition
30. Molecular cloning of a novel gene similar to myeloid antigen CD33 and its specific expression in placenta
31. Identification of SAF-2, a novel siglec expressed on eosinophils, mast cells, and basophils
32. Structure of a selectin-like mutant of mannose-binding protein complexed with sialylated and sulfated Lewis (x) oligosaccharides
33. Crystal structure of the N-terminal domain of sialoadhesin in complex with 3′ sialyllactose at 1.85 a resolution
34. Characterization of the sialic acid-binding site in sialoadhesin by site-directed mutagenesis
35. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22
36. Molecular analysis of sialoside binding to sialoadhesin by NMR and site-directed mutagenesis
37. Sialylation of the B lymphocyte molecule CD22 by alpha 2.6-sialyltransferase is implicated in the regulation of CD22-mediated adhesion
38. Immune regulation by the ST6Gal sialyltransferase
39. Masking and unmasking of the sialic acid-binding lectin activity of CD22 (Siglec-2) on B lymphocytes
40. CD22 associates with the human surface IgM-B-cell antigen receptor complex
41. Association of CD22 with the B cell antigen receptor
42. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP
43. Inhibition of the B cell by CD22: A requirement for Lyn
44. Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22
45. CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux
46. CD22 is a negative regulator of B-cell receptor signalling
47. Hyperresponsive B cells in CD22-deficient mice
48. CD22 regulates thymus-independent responses and the lifespan of B cells
49. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: Altered signaling in CD22-deficient mice
50. Deficiency in CD22, a B cell-specific inhibitory receptor, is sufficient to predispose to development of high affinity autoantibodies
51. Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
52. Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop
53. Counterregulation by the coreceptors CD19 and CD22 of MAP kinase activation by membrane immunoglobulin
54. Identification of CD22 ligands on bone marrow sinusoidal endothelium implicated in CD22-dependent homing of recirculating B cells
55. A novel subset of murine B cells expressing unmasked forms of CD22 are enriched in the bone marrow
56. Memory B lymphocytes migrate to bone marrow in humans
57. Human immunoglobulin (Ig) M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (Memory) B cells
58. Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and gamma-irradiated mice
59. Constitutive expression of E-selectin and vascular cell adhesion molecule-1 on endothelial cells of hematopoietic tissues
60. Hematopoietic progenitor cell rolling in bone marrow microvessels: Parallel contributions by endothelial selectins and vascular cell adhesion molecule 1