Low 2-dimensional CD4 T cell receptor affinity for myelin sets in motion delayed response kinetics

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Rosenthal, Kristen M ^a   Edwards, Lindsay J ^a   Sabatino, Joseph J ^a   Hood, Jennifer D ^a   Wasserman, Heather A ^a   Zhu, Cheng ^b   Evavold, Brian D ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; CYTOKINE; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN; PROTEIN C JUN; PROTEIN TYROSINE PHOSPHATASE SHP 1; SYNAPTOPHYSIN; T LYMPHOCYTE RECEPTOR; BIOLOGICAL MARKER; EPITOPE; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE;

ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREACTIVITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE; VIRUS LOAD; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CELL PROLIFERATION; CHEMISTRY; IMMUNOLOGY; IMMUNOPHENOTYPING; KINETICS; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; MYELIN SHEATH; PROTEIN BINDING;

MUS MUSCULUS;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL PROLIFERATION; EPITOPES, T-LYMPHOCYTE; IMMUNOPHENOTYPING; KINETICS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MYELIN SHEATH; PEPTIDES; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION;

EID: 84857853669     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032562     Document Type: Article

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