메뉴 건너뛰기




Volumn 103, Issue 6, 2004, Pages 2187-2195

Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 1542373657     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-08-2729     Document Type: Article
Times cited : (166)

References (65)
  • 1
    • 0034773298 scopus 로고    scopus 로고
    • Presentation of antigens by MHC class II molecules: Getting the most out of them
    • Villadangos JA. Presentation of antigens by MHC class II molecules: getting the most out of them. Mol Immunol. 2001;38:329-346.
    • (2001) Mol Immunol , vol.38 , pp. 329-346
    • Villadangos, J.A.1
  • 2
    • 0028344533 scopus 로고
    • Structure of peptides associated with class I and class II MHC molecules
    • Engelhard VH. Structure of peptides associated with class I and class II MHC molecules. Annu Rev Immunol. 1994;12:181-207.
    • (1994) Annu Rev Immunol , vol.12 , pp. 181-207
    • Engelhard, V.H.1
  • 3
    • 0034998413 scopus 로고    scopus 로고
    • In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses
    • Dongre AR, Kovats S, deRoos P, et al. In vivo MHC class II presentation of cytosolic proteins revealed by rapid automated tandem mass spectrometry and functional analyses. Eur J Immunol. 2001;31:1485-1494.
    • (2001) Eur J Immunol , vol.31 , pp. 1485-1494
    • Dongre, A.R.1    Kovats, S.2    DeRoos, P.3
  • 5
    • 0021917676 scopus 로고
    • Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro
    • Schuler G, Steinman RM. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro. J Exp Med. 1985;161:526-546.
    • (1985) J Exp Med , vol.161 , pp. 526-546
    • Schuler, G.1    Steinman, R.M.2
  • 7
    • 0037769110 scopus 로고    scopus 로고
    • Dendritic cells in immunity and tolerance: Do they display opposite functions?
    • Moser M. Dendritic cells in immunity and tolerance: do they display opposite functions? Immunity. 2003;19:5-8.
    • (2003) Immunity , vol.19 , pp. 5-8
    • Moser, M.1
  • 8
    • 0032568806 scopus 로고    scopus 로고
    • Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells
    • Pierre P, Mellman I. Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells. Cell. 1998;93:1135-1145.
    • (1998) Cell , vol.93 , pp. 1135-1145
    • Pierre, P.1    Mellman, I.2
  • 9
    • 0034689004 scopus 로고    scopus 로고
    • The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli
    • Inaba K, Turley S, Iyoda T, et al. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J Exp Med. 2000;191:927-936.
    • (2000) J Exp Med , vol.191 , pp. 927-936
    • Inaba, K.1    Turley, S.2    Iyoda, T.3
  • 10
    • 0034697282 scopus 로고    scopus 로고
    • Transport of peptide-MHC class II complexes in developing dendritic cells
    • Turley SJ, Inaba K, Garrett WS, et al. Transport of peptide-MHC class II complexes in developing dendritic cells. Science. 2000;288:522-527.
    • (2000) Science , vol.288 , pp. 522-527
    • Turley, S.J.1    Inaba, K.2    Garrett, W.S.3
  • 11
    • 0035494424 scopus 로고    scopus 로고
    • Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
    • Kleijmeer M, Ramm G, Schuurhuis D, et al. Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol. 2001;155:53-63.
    • (2001) J Cell Biol , vol.155 , pp. 53-63
    • Kleijmeer, M.1    Ramm, G.2    Schuurhuis, D.3
  • 12
    • 0030869567 scopus 로고    scopus 로고
    • Developmental regulation of MHC class II transport in mouse dendritic cells
    • Pierre P, Turley SJ, Gatti E, et al. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature. 1997;388:787-792.
    • (1997) Nature , vol.388 , pp. 787-792
    • Pierre, P.1    Turley, S.J.2    Gatti, E.3
  • 13
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella M, Engering A, Pinet V, Pieters J, Lanzavecchia A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature. 1997;388:782-787.
    • (1997) Nature , vol.388 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 14
    • 0032574816 scopus 로고    scopus 로고
    • Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells
    • Rescigno M, Citterio S, Thery C, et al. Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. Proc Natl Acad Sci U S A. 1998;95:5229-5234.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5229-5234
    • Rescigno, M.1    Citterio, S.2    Thery, C.3
  • 15
    • 0034954037 scopus 로고    scopus 로고
    • MHC class II expression is regulated in dendritic cells independently of invariant chain degradation
    • Villadangos JA, Cardoso M, Steptoe RJ, et al. MHC class II expression is regulated in dendritic cells independently of invariant chain degradation. Immunity. 2001;14:739-749.
    • (2001) Immunity , vol.14 , pp. 739-749
    • Villadangos, J.A.1    Cardoso, M.2    Steptoe, R.J.3
  • 16
    • 0036857827 scopus 로고    scopus 로고
    • Rapid constitutive generation of a specific peptide-MHC class II complex from intact exogenous protein in immature dendritic cells
    • Colledge L, Bennett CL, Reay PA, Blackburn CC. Rapid constitutive generation of a specific peptide-MHC class II complex from intact exogenous protein in immature dendritic cells. Eur J Immunol. 2002;32:3246-3255.
    • (2002) Eur J Immunol , vol.32 , pp. 3246-3255
    • Colledge, L.1    Bennett, C.L.2    Reay, P.A.3    Blackburn, C.C.4
  • 17
    • 0038528584 scopus 로고    scopus 로고
    • Dendritic cells process and present antigens across a range of maturation states
    • Veeraswamy RK, Cella M, Colonna M, Unanue ER. Dendritic cells process and present antigens across a range of maturation states. J Immunol. 2003;170:5367-5372.
    • (2003) J Immunol , vol.170 , pp. 5367-5372
    • Veeraswamy, R.K.1    Cella, M.2    Colonna, M.3    Unanue, E.R.4
  • 18
    • 0242495719 scopus 로고    scopus 로고
    • The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation
    • El-Sukkari D, Wilson NS, Hakansson K, et al. The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation. J Immunol. 2003;171:5003-5011.
    • (2003) J Immunol , vol.171 , pp. 5003-5011
    • El-Sukkari, D.1    Wilson, N.S.2    Hakansson, K.3
  • 19
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
    • Finkelman FD, Lees A, Birnbaum R, Gause WC, Morris SC. Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. J Immunol. 1996;157:1406-1414.
    • (1996) J Immunol , vol.157 , pp. 1406-1414
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3    Gause, W.C.4    Morris, S.C.5
  • 20
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med. 2001;194:769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3
  • 21
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci U S A. 2002;99:351-358.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 22
    • 0142122407 scopus 로고    scopus 로고
    • Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection
    • Ehst BD, Ingulli E, Jenkins MK. Development of a novel transgenic mouse for the study of interactions between CD4 and CD8 T cells during graft rejection. Am J Transplant. 2003;3:1355-1362.
    • (2003) Am J Transplant , vol.3 , pp. 1355-1362
    • Ehst, B.D.1    Ingulli, E.2    Jenkins, M.K.3
  • 23
    • 0034653434 scopus 로고    scopus 로고
    • CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen
    • Vremec D, Pooley J, Hochrein H, Wu L, Shortman K. CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen. J Immunol. 2000;164:2978-2986.
    • (2000) J Immunol , vol.164 , pp. 2978-2986
    • Vremec, D.1    Pooley, J.2    Hochrein, H.3    Wu, L.4    Shortman, K.5
  • 24
    • 0035879278 scopus 로고    scopus 로고
    • The dendritic cell populations of mouse lymph nodes
    • Henri S, Vremec D, Kamath A, et al. The dendritic cell populations of mouse lymph nodes. J Immunol. 2001;167:741-748.
    • (2001) J Immunol , vol.167 , pp. 741-748
    • Henri, S.1    Vremec, D.2    Kamath, A.3
  • 25
    • 0141678970 scopus 로고    scopus 로고
    • Most lymphoid organ dendritic cell types are phenotypically and functionally immature
    • Wilson NS, El-Sukkari D, Belz GT, et al. Most lymphoid organ dendritic cell types are phenotypically and functionally immature. Blood. 2003;102:2187-2194.
    • (2003) Blood , vol.102 , pp. 2187-2194
    • Wilson, N.S.1    El-Sukkari, D.2    Belz, G.T.3
  • 26
    • 0037131976 scopus 로고    scopus 로고
    • Mouse plasmacytoid cells: Long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus
    • O'Keeffe M, Hochrein H, Vremec D, et al. Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus. J Exp Med. 2002;196:1307-1319.
    • (2002) J Exp Med , vol.196 , pp. 1307-1319
    • O'Keeffe, M.1    Hochrein, H.2    Vremec, D.3
  • 27
    • 0029812040 scopus 로고    scopus 로고
    • Constitutive class I-restricted exogenous presentation of self antigens in vivo
    • Kurts C, Heath WR, Carbone FR, Allison J, Miller JF, Kosaka H. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med. 1996;184:923-930.
    • (1996) J Exp Med , vol.184 , pp. 923-930
    • Kurts, C.1    Heath, W.R.2    Carbone, F.R.3    Allison, J.4    Miller, J.F.5    Kosaka, H.6
  • 28
  • 29
    • 0030790341 scopus 로고    scopus 로고
    • Degradation of mouse invariant chain: Roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism
    • Villadangos JA, Riese RJ, Peters C, Chapman HA, Ploegh HL. Degradation of mouse invariant chain: Roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism. J Exp Med. 1997;186:549-560.
    • (1997) J Exp Med , vol.186 , pp. 549-560
    • Villadangos, J.A.1    Riese, R.J.2    Peters, C.3    Chapman, H.A.4    Ploegh, H.L.5
  • 30
    • 0036518287 scopus 로고    scopus 로고
    • Mouse and human dendritic cell subtypes
    • Shortman K, Liu YJ. Mouse and human dendritic cell subtypes. Nat Rev Immunol. 2002;2:151-161.
    • (2002) Nat Rev Immunol , vol.2 , pp. 151-161
    • Shortman, K.1    Liu, Y.J.2
  • 31
    • 0031058029 scopus 로고    scopus 로고
    • Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures
    • Winzler C, Rovere P, Rescigno M, et al. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J Exp Med. 1997;185:317-328.
    • (1997) J Exp Med , vol.185 , pp. 317-328
    • Winzler, C.1    Rovere, P.2    Rescigno, M.3
  • 32
    • 0025826118 scopus 로고
    • MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
    • Germain RN, Hendrix LR. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature. 1991;353:134-139.
    • (1991) Nature , vol.353 , pp. 134-139
    • Germain, R.N.1    Hendrix, L.R.2
  • 33
    • 0026345419 scopus 로고
    • Class II major histocompatibility complex molecules of murine dendritic cells: Synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture
    • Kampgen E, Koch N, Koch F, et al. Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture. Proc Natl Acad Sci U S A. 1991;88:3014-3018.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3014-3018
    • Kampgen, E.1    Koch, N.2    Koch, F.3
  • 34
    • 0034161292 scopus 로고    scopus 로고
    • Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM
    • Villadangos JA, Driessen C, Shi GP, Chapman HA, Ploegh HL. Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM. EMBO J. 2000;19:882-891.
    • (2000) EMBO J , vol.19 , pp. 882-891
    • Villadangos, J.A.1    Driessen, C.2    Shi, G.P.3    Chapman, H.A.4    Ploegh, H.L.5
  • 35
    • 0036721329 scopus 로고    scopus 로고
    • Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
    • Kamath AT, Henri S, Battye F, Tough DF, Shortman K. Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs. Blood. 2002;100:1734-1741.
    • (2002) Blood , vol.100 , pp. 1734-1741
    • Kamath, A.T.1    Henri, S.2    Battye, F.3    Tough, D.F.4    Shortman, K.5
  • 36
    • 0029905555 scopus 로고    scopus 로고
    • Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo
    • De Smedt T, Pajak B, Muraille E, et al. Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo. J Exp Med. 1996;184:1413-1424.
    • (1996) J Exp Med , vol.184 , pp. 1413-1424
    • De Smedt, T.1    Pajak, B.2    Muraille, E.3
  • 37
    • 0033697454 scopus 로고    scopus 로고
    • CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
    • Schulz O, Edwards AD, Schito M, et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity. 2000;13:453-462.
    • (2000) Immunity , vol.13 , pp. 453-462
    • Schulz, O.1    Edwards, A.D.2    Schito, M.3
  • 38
    • 0033151915 scopus 로고    scopus 로고
    • Analysis of adjuvant function by direct visualization of antigen presentation in vivo: Endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue
    • Reis e Sousa C, Germain RN. Analysis of adjuvant function by direct visualization of antigen presentation in vivo: endotoxin promotes accumulation of antigen-bearing dendritic cells in the T cell areas of lymphoid tissue. J Immunol. 1999;162:6552-6561.
    • (1999) J Immunol , vol.162 , pp. 6552-6561
    • Reis E Sousa, C.1    Germain, R.N.2
  • 39
    • 0031974804 scopus 로고    scopus 로고
    • Three populations of mouse lymph node dendritic cells with different origins and dynamics
    • Salomon B, Cohen JL, Masurier C, Klatzmann D. Three populations of mouse lymph node dendritic cells with different origins and dynamics. J Immunol. 1998;160:708-717.
    • (1998) J Immunol , vol.160 , pp. 708-717
    • Salomon, B.1    Cohen, J.L.2    Masurier, C.3    Klatzmann, D.4
  • 40
    • 0034672034 scopus 로고    scopus 로고
    • The development, maturation, and turnover rate of mouse spleen dendritic cell populations
    • Kamath AT, Pooley J, O'Keeffe MA, et al. The development, maturation, and turnover rate of mouse spleen dendritic cell populations. J Immunol. 2000;165:6762-6770.
    • (2000) J Immunol , vol.165 , pp. 6762-6770
    • Kamath, A.T.1    Pooley, J.2    O'Keeffe, M.A.3
  • 41
    • 0037769037 scopus 로고    scopus 로고
    • Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
    • Itano AA, McSorley SJ, Reinhardt RL, et al. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity. 2003;19:47-57.
    • (2003) Immunity , vol.19 , pp. 47-57
    • Itano, A.A.1    McSorley, S.J.2    Reinhardt, R.L.3
  • 42
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • Huang FP, Platt N, Wykes M, et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med. 2000;191:435-444.
    • (2000) J Exp Med , vol.191 , pp. 435-444
    • Huang, F.P.1    Platt, N.2    Wykes, M.3
  • 43
    • 0033403066 scopus 로고    scopus 로고
    • Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo
    • Randolph GJ, Inaba K, Robbiani DF, Steinman RM, Muller WA. Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo. Immunity. 1999;11:753-761.
    • (1999) Immunity , vol.11 , pp. 753-761
    • Randolph, G.J.1    Inaba, K.2    Robbiani, D.F.3    Steinman, R.M.4    Muller, W.A.5
  • 44
    • 0035177431 scopus 로고    scopus 로고
    • Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes
    • Vermaelen KY, Carro-Muino I, Lambrecht BN, Pauwels RA. Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes. J Exp Med. 2001;193:51-60.
    • (2001) J Exp Med , vol.193 , pp. 51-60
    • Vermaelen, K.Y.1    Carro-Muino, I.2    Lambrecht, B.N.3    Pauwels, R.A.4
  • 45
    • 0029911692 scopus 로고    scopus 로고
    • A life stage of particle-laden rat dendritic cells in vivo: Their terminal division, active phagocytosis, and translocation from the liver to the draining lymph
    • Matsuno K, Ezaki T, Kudo S, Uehara Y. A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph. J Exp Med. 1996;183:1865-1878.
    • (1996) J Exp Med , vol.183 , pp. 1865-1878
    • Matsuno, K.1    Ezaki, T.2    Kudo, S.3    Uehara, Y.4
  • 46
    • 0042696999 scopus 로고    scopus 로고
    • Antigen presentation to naive CD4 T cells in the lymph node
    • Itano AA, Jenkins MK. Antigen presentation to naive CD4 T cells in the lymph node. Nat Immunol. 2003;4:733-739.
    • (2003) Nat Immunol , vol.4 , pp. 733-739
    • Itano, A.A.1    Jenkins, M.K.2
  • 47
    • 0035406398 scopus 로고    scopus 로고
    • Phenotypic characterization of five dendritic cell subsets in human tonsils
    • Summers KL, Hock BD, McKenzie JL, Hart DN. Phenotypic characterization of five dendritic cell subsets in human tonsils. Am J Pathol. 2001;159:285-295.
    • (2001) Am J Pathol , vol.159 , pp. 285-295
    • Summers, K.L.1    Hock, B.D.2    McKenzie, J.L.3    Hart, D.N.4
  • 48
    • 0035383796 scopus 로고    scopus 로고
    • Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors
    • McIlroy D, Troadec C, Grassi F, et al. Investigation of human spleen dendritic cell phenotype and distribution reveals evidence of in vivo activation in a subset of organ donors. Blood. 2001;97:3470-3477.
    • (2001) Blood , vol.97 , pp. 3470-3477
    • McIlroy, D.1    Troadec, C.2    Grassi, F.3
  • 49
    • 0033571691 scopus 로고    scopus 로고
    • Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells
    • Driessen C, Bryant RA, Lennon-Dumenil AM, et al. Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. J Cell Biol. 1999;147:775-790.
    • (1999) J Cell Biol , vol.147 , pp. 775-790
    • Driessen, C.1    Bryant, R.A.2    Lennon-Dumenil, A.M.3
  • 50
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • Scheinecker C, McHugh R, Shevach EM, Germain RN. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J Exp Med. 2002;196:1079-1090.
    • (2002) J Exp Med , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 51
    • 0037152141 scopus 로고    scopus 로고
    • The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens
    • Belz GT, Behrens GM, Smith CM, et al. The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J Exp Med. 2002;196:1099-1104.
    • (2002) J Exp Med , vol.196 , pp. 1099-1104
    • Belz, G.T.1    Behrens, G.M.2    Smith, C.M.3
  • 52
    • 1842377506 scopus 로고    scopus 로고
    • Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro
    • Zhong G, Sousa CR, Germain RN. Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro. J Exp Med. 1997;186:673-682.
    • (1997) J Exp Med , vol.186 , pp. 673-682
    • Zhong, G.1    Sousa, C.R.2    Germain, R.N.3
  • 53
    • 0035340499 scopus 로고    scopus 로고
    • Cutting edge: Intravenous soluble antigen is presented to CD4 T cells by CD8-dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells
    • Pooley JL, Heath WR, Shortman K. Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8-dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells. J Immunol. 2001;166:5327-5330.
    • (2001) J Immunol , vol.166 , pp. 5327-5330
    • Pooley, J.L.1    Heath, W.R.2    Shortman, K.3
  • 54
    • 0031798137 scopus 로고    scopus 로고
    • Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells
    • Inaba K, Turley S, Yamaide F, et al. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J Exp Med. 1998;188:2163-2173.
    • (1998) J Exp Med , vol.188 , pp. 2163-2173
    • Inaba, K.1    Turley, S.2    Yamaide, F.3
  • 55
    • 0032193687 scopus 로고    scopus 로고
    • The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules
    • Hammond C, Denzin LK, Pan M, Griffith JM, Geuze HJ, Cresswell P. The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules. J Immunol. 1998;161:3282-3291.
    • (1998) J Immunol , vol.161 , pp. 3282-3291
    • Hammond, C.1    Denzin, L.K.2    Pan, M.3    Griffith, J.M.4    Geuze, H.J.5    Cresswell, P.6
  • 56
    • 0034252971 scopus 로고    scopus 로고
    • Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation
    • Anderson HA, Hiltbold EM, Roche PA. Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation. Nat Immunol. 2000;1:156-162.
    • (2000) Nat Immunol , vol.1 , pp. 156-162
    • Anderson, H.A.1    Hiltbold, E.M.2    Roche, P.A.3
  • 57
    • 0035144246 scopus 로고    scopus 로고
    • Association of distinct tetraspanins with MHC class II molecules at different subcellular locations in human immature dendritic cells
    • Engering A, Pieters J. Association of distinct tetraspanins with MHC class II molecules at different subcellular locations in human immature dendritic cells. Int Immunol. 2001;13:127-134.
    • (2001) Int Immunol , vol.13 , pp. 127-134
    • Engering, A.1    Pieters, J.2
  • 58
    • 0036144745 scopus 로고    scopus 로고
    • Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes
    • Kropshofer H, Spindeldreher S, Rohn TA, et al. Tetraspan microdomains distinct from lipid rafts enrich select peptide-MHC class II complexes. Nat Immunol. 2002;3:61-68.
    • (2002) Nat Immunol , vol.3 , pp. 61-68
    • Kropshofer, H.1    Spindeldreher, S.2    Rohn, T.A.3
  • 59
    • 0038054203 scopus 로고    scopus 로고
    • Differential post-translational modification of CD63 molecules during maturation of human dendritic cells
    • Engering A, Kuhn L, Fluitsma D, Hoefsmit E, Pieters J. Differential post-translational modification of CD63 molecules during maturation of human dendritic cells. Eur J Biochem. 2003;270:2412-2420.
    • (2003) Eur J Biochem , vol.270 , pp. 2412-2420
    • Engering, A.1    Kuhn, L.2    Fluitsma, D.3    Hoefsmit, E.4    Pieters, J.5
  • 60
    • 0037194784 scopus 로고    scopus 로고
    • T-cell engagement of dendritic cells rapidly rearranges MHC class II transport
    • Boes M, Cerny J, Massol R, et al. T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature. 2002;418:983-988.
    • (2002) Nature , vol.418 , pp. 983-988
    • Boes, M.1    Cerny, J.2    Massol, R.3
  • 61
    • 0037194733 scopus 로고    scopus 로고
    • Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane
    • Chow A, Toomre D, Garrett W, Mellman I. Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane. Nature. 2002;418:988-994.
    • (2002) Nature , vol.418 , pp. 988-994
    • Chow, A.1    Toomre, D.2    Garrett, W.3    Mellman, I.4
  • 62
    • 1842843536 scopus 로고    scopus 로고
    • MHC class II compartments in human dendritic cells undergo profound structural changes upon activation
    • Barois N, de Saint-Vis B, Lebecque S, Geuze HJ, Kleijmeer MJ. MHC class II compartments in human dendritic cells undergo profound structural changes upon activation. Traffic. 2002;3:894-905.
    • (2002) Traffic , vol.3 , pp. 894-905
    • Barois, N.1    De Saint-Vis, B.2    Lebecque, S.3    Geuze, H.J.4    Kleijmeer, M.J.5
  • 63
    • 0141889165 scopus 로고    scopus 로고
    • T cells induce extended class II MHC compartments in dendritic cells in a toll-like receptor-dependent manner
    • Boes M, Bertho N, Cerny J, Op Den Brouw M, Kirchhausen T, Ploegh H. T cells induce extended class II MHC compartments in dendritic cells in a toll-like receptor-dependent manner. J Immunol. 2003;171:4081-4088.
    • (2003) J Immunol , vol.171 , pp. 4081-4088
    • Boes, M.1    Bertho, N.2    Cerny, J.3    Op Den Brouw, M.4    Kirchhausen, T.5    Ploegh, H.6
  • 64
    • 0344153938 scopus 로고    scopus 로고
    • Requirements for T cell-polarized tubulation of class II(+) compartments in dendritic cells
    • Bertho N, Cerny J, Kim YM, Fiebiger E, Ploegh H, Boes M. Requirements for T cell-polarized tubulation of class II(+) compartments in dendritic cells. J Immunol. 2003;171:5689-5696.
    • (2003) J Immunol , vol.171 , pp. 5689-5696
    • Bertho, N.1    Cerny, J.2    Kim, Y.M.3    Fiebiger, E.4    Ploegh, H.5    Boes, M.6
  • 65
    • 0035877191 scopus 로고    scopus 로고
    • In vivo-matured Langerhans cells continue to take up and process native proteins unlike in vitro-matured counter-parts
    • Ruedl C, Koebel P, Karjalainen K. In vivo-matured Langerhans cells continue to take up and process native proteins unlike in vitro-matured counter-parts. J Immunol. 2001;166:7178-7182.
    • (2001) J Immunol , vol.166 , pp. 7178-7182
    • Ruedl, C.1    Koebel, P.2    Karjalainen, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.