TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4+ T cell clone

European Journal of Immunology

Volumn 36, Issue 7, 2006, Pages 1926-1937

  Tsukamoto, Hirotake ^a   Irie, Atsushi ^a   Chen, Yu Zhen ^a   Takeshita, Kumiko ^a   Kim, Jeong Ran ^a   Nishimura, Yasuharu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

B Raf; Cellular activation; Low avidity TCR ligand; Signal transduction; TCR

Indexed keywords

B RAF KINASE; CD69 ANTIGEN; HLA DR4 ANTIGEN; INTERLEUKIN 2; LAT PROTEIN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PROTEIN KINASE ZAP 70; RAF PROTEIN; T LYMPHOCYTE RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CLONE; LYMPHOCYTE CULTURE; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; AOTIDAE; CD4-POSITIVE T-LYMPHOCYTES; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; CLONE CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HERPESVIRUS 2, SAIMIRIINE; HLA-DR4 ANTIGEN; HUMANS; JURKAT CELLS; L CELLS (CELL LINE); LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; PC12 CELLS; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RECEPTORS, ANTIGEN, T-CELL;

EID: 33746238511     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535803     Document Type: Article

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