메뉴 건너뛰기




Volumn 34, Issue 1, 2011, Pages 13-23

Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

EID: 78751696945     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.12.017     Document Type: Article
Times cited : (135)

References (53)
  • 3
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
    • Campi G., Varma R., Dustin M.L. Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 2005, 202:1031-1036.
    • (2005) J. Exp. Med. , vol.202 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 4
    • 0031682733 scopus 로고    scopus 로고
    • Measuring two-dimensional receptor-ligand binding kinetics by micropipette
    • Chesla S.E., Selvaraj P., Zhu C. Measuring two-dimensional receptor-ligand binding kinetics by micropipette. Biophys. J. 1998, 75:1553-1572.
    • (1998) Biophys. J. , vol.75 , pp. 1553-1572
    • Chesla, S.E.1    Selvaraj, P.2    Zhu, C.3
  • 5
    • 0034677055 scopus 로고    scopus 로고
    • Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
    • Daniels M.A., Jameson S.C. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers. J. Exp. Med. 2000, 191:335-346.
    • (2000) J. Exp. Med. , vol.191 , pp. 335-346
    • Daniels, M.A.1    Jameson, S.C.2
  • 9
    • 2442642497 scopus 로고    scopus 로고
    • Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation
    • Devine L., Hodsdon M.E., Daniels M.A., Jameson S.C., Kavathas P.B. Location of the epitope for an anti-CD8alpha antibody 53.6.7 which enhances CD8alpha-MHC class I interaction indicates antibody stabilization of a higher affinity CD8 conformation. Immunol. Lett. 2004, 93:123-130.
    • (2004) Immunol. Lett. , vol.93 , pp. 123-130
    • Devine, L.1    Hodsdon, M.E.2    Daniels, M.A.3    Jameson, S.C.4    Kavathas, P.B.5
  • 11
    • 0026434554 scopus 로고
    • Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand
    • Evavold B.D., Allen P.M. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 1991, 252:1308-1310.
    • (1991) Science , vol.252 , pp. 1308-1310
    • Evavold, B.D.1    Allen, P.M.2
  • 12
    • 0027333348 scopus 로고
    • Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
    • Evavold B.D., Sloan-Lancaster J., Allen P.M. Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands. Immunol. Today 1993, 14:602-609.
    • (1993) Immunol. Today , vol.14 , pp. 602-609
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Allen, P.M.3
  • 13
    • 0042847235 scopus 로고    scopus 로고
    • Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55
    • Ford M.L., Evavold B.D. Regulation of polyclonal T cell responses by an MHC anchor-substituted variant of myelin oligodendrocyte glycoprotein 35-55. J. Immunol. 2003, 171:1247-1254.
    • (2003) J. Immunol. , vol.171 , pp. 1247-1254
    • Ford, M.L.1    Evavold, B.D.2
  • 16
    • 0036667342 scopus 로고    scopus 로고
    • Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands
    • Gao G.F., Rao Z., Bell J.I. Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends Immunol. 2002, 23:408-413.
    • (2002) Trends Immunol. , vol.23 , pp. 408-413
    • Gao, G.F.1    Rao, Z.2    Bell, J.I.3
  • 19
    • 15444362931 scopus 로고    scopus 로고
    • Characterizing the impact of CD8 antibodies on class I MHC multimer binding
    • Holman P.O., Walsh E.R., Jameson S.C. Characterizing the impact of CD8 antibodies on class I MHC multimer binding. J. Immunol. 2005, 174:3986-3991.
    • (2005) J. Immunol. , vol.174 , pp. 3986-3991
    • Holman, P.O.1    Walsh, E.R.2    Jameson, S.C.3
  • 20
    • 38349108802 scopus 로고    scopus 로고
    • Kinetics of MHC-CD8 interaction at the T cell membrane
    • Huang J., Edwards L.J., Evavold B.D., Zhu C. Kinetics of MHC-CD8 interaction at the T cell membrane. J. Immunol. 2007, 179:7653-7662.
    • (2007) J. Immunol. , vol.179 , pp. 7653-7662
    • Huang, J.1    Edwards, L.J.2    Evavold, B.D.3    Zhu, C.4
  • 21
    • 77950809538 scopus 로고    scopus 로고
    • The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
    • Huang J., Zarnitsyna V.I., Liu B., Edwards L.J., Jiang N., Evavold B.D., Zhu C. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness. Nature 2010, 464:932-936.
    • (2010) Nature , vol.464 , pp. 932-936
    • Huang, J.1    Zarnitsyna, V.I.2    Liu, B.3    Edwards, L.J.4    Jiang, N.5    Evavold, B.D.6    Zhu, C.7
  • 23
    • 34447647655 scopus 로고    scopus 로고
    • Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist
    • Huse M., Klein L.O., Girvin A.T., Faraj J.M., Li Q.J., Kuhns M.S., Davis M.M. Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. Immunity 2007, 27:76-88.
    • (2007) Immunity , vol.27 , pp. 76-88
    • Huse, M.1    Klein, L.O.2    Girvin, A.T.3    Faraj, J.M.4    Li, Q.J.5    Kuhns, M.S.6    Davis, M.M.7
  • 24
    • 0037167816 scopus 로고    scopus 로고
    • Direct observation of ligand recognition by T cells
    • Irvine D.J., Purbhoo M.A., Krogsgaard M., Davis M.M. Direct observation of ligand recognition by T cells. Nature 2002, 419:845-849.
    • (2002) Nature , vol.419 , pp. 845-849
    • Irvine, D.J.1    Purbhoo, M.A.2    Krogsgaard, M.3    Davis, M.M.4
  • 25
    • 0038578823 scopus 로고    scopus 로고
    • The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3
    • Kane L.P., Weiss A. The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3. Immunol. Rev. 2003, 192:7-20.
    • (2003) Immunol. Rev. , vol.192 , pp. 7-20
    • Kane, L.P.1    Weiss, A.2
  • 26
    • 0032191836 scopus 로고    scopus 로고
    • Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb
    • Kern P.S., Teng M.K., Smolyar A., Liu J.H., Liu J., Hussey R.E., Spoerl R., Chang H.C., Reinherz E.L., Wang J.H. Structural basis of CD8 coreceptor function revealed by crystallographic analysis of a murine CD8alphaalpha ectodomain fragment in complex with H-2Kb. Immunity 1998, 9:519-530.
    • (1998) Immunity , vol.9 , pp. 519-530
    • Kern, P.S.1    Teng, M.K.2    Smolyar, A.3    Liu, J.H.4    Liu, J.5    Hussey, R.E.6    Spoerl, R.7    Chang, H.C.8    Reinherz, E.L.9    Wang, J.H.10
  • 29
    • 34548264739 scopus 로고    scopus 로고
    • Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties
    • Laugel B., van den Berg H.A., Gostick E., Cole D.K., Wooldridge L., Boulter J., Milicic A., Price D.A., Sewell A.K. Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties. J. Biol. Chem. 2007, 282:23799-23810.
    • (2007) J. Biol. Chem. , vol.282 , pp. 23799-23810
    • Laugel, B.1    van den Berg, H.A.2    Gostick, E.3    Cole, D.K.4    Wooldridge, L.5    Boulter, J.6    Milicic, A.7    Price, D.A.8    Sewell, A.K.9
  • 30
    • 77953473256 scopus 로고    scopus 로고
    • Cutting edge: Mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling
    • Li Y.C., Chen B.M., Wu P.C., Cheng T.L., Kao L.S., Tao M.H., Lieber A., Roffler S.R. Cutting edge: Mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling. J. Immunol. 2010, 184:5959-5963.
    • (2010) J. Immunol. , vol.184 , pp. 5959-5963
    • Li, Y.C.1    Chen, B.M.2    Wu, P.C.3    Cheng, T.L.4    Kao, L.S.5    Tao, M.H.6    Lieber, A.7    Roffler, S.R.8
  • 31
    • 0028797801 scopus 로고
    • CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes
    • Luescher I.F., Vivier E., Layer A., Mahiou J., Godeau F., Malissen B., Romero P. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 1995, 373:353-356.
    • (1995) Nature , vol.373 , pp. 353-356
    • Luescher, I.F.1    Vivier, E.2    Layer, A.3    Mahiou, J.4    Godeau, F.5    Malissen, B.6    Romero, P.7
  • 33
    • 7944231534 scopus 로고    scopus 로고
    • Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation
    • Palacios E.H., Weiss A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 2004, 23:7990-8000.
    • (2004) Oncogene , vol.23 , pp. 7990-8000
    • Palacios, E.H.1    Weiss, A.2
  • 34
    • 20444381329 scopus 로고    scopus 로고
    • Spatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells
    • Pecht I., Gakamsky D.M. Spatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells. FEBS Lett. 2005, 579:3336-3341.
    • (2005) FEBS Lett. , vol.579 , pp. 3336-3341
    • Pecht, I.1    Gakamsky, D.M.2
  • 35
    • 2442651482 scopus 로고    scopus 로고
    • T cell killing does not require the formation of a stable mature immunological synapse
    • Purbhoo M.A., Irvine D.J., Huppa J.B., Davis M.M. T cell killing does not require the formation of a stable mature immunological synapse. Nat. Immunol. 2004, 5:524-530.
    • (2004) Nat. Immunol. , vol.5 , pp. 524-530
    • Purbhoo, M.A.1    Irvine, D.J.2    Huppa, J.B.3    Davis, M.M.4
  • 37
    • 44449165047 scopus 로고    scopus 로고
    • Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen
    • Sabatino J.J., Shires J., Altman J.D., Ford M.L., Evavold B.D. Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen. J. Immunol. 2008, 180:4451-4457.
    • (2008) J. Immunol. , vol.180 , pp. 4451-4457
    • Sabatino, J.J.1    Shires, J.2    Altman, J.D.3    Ford, M.L.4    Evavold, B.D.5
  • 38
    • 0036909439 scopus 로고    scopus 로고
    • Inefficient clustering of tyrosine-phosphorylated proteins at the immunological synapse in response to an antagonist peptide
    • Smyth L.A., Ardouin L., Williams O., Norton T., Tybulewicz V., Kioussis D. Inefficient clustering of tyrosine-phosphorylated proteins at the immunological synapse in response to an antagonist peptide. Eur. J. Immunol. 2002, 32:3386-3394.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3386-3394
    • Smyth, L.A.1    Ardouin, L.2    Williams, O.3    Norton, T.4    Tybulewicz, V.5    Kioussis, D.6
  • 39
    • 0029008301 scopus 로고
    • Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex
    • Thome M., Duplay P., Guttinger M., Acuto O. Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T cell receptor/CD3/zeta complex. J. Exp. Med. 1995, 181:1997-2006.
    • (1995) J. Exp. Med. , vol.181 , pp. 1997-2006
    • Thome, M.1    Duplay, P.2    Guttinger, M.3    Acuto, O.4
  • 40
    • 0029661957 scopus 로고    scopus 로고
    • The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex
    • Thome M., Germain V., DiSanto J.P., Acuto O. The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex. Eur. J. Immunol. 1996, 26:2093-2100.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2093-2100
    • Thome, M.1    Germain, V.2    DiSanto, J.P.3    Acuto, O.4
  • 41
    • 0025644536 scopus 로고
    • Epitope-specific binding of CD8 regulates activation of T cells and induction of cytotoxicity
    • Tomonari K., Spencer S. Epitope-specific binding of CD8 regulates activation of T cells and induction of cytotoxicity. Int. Immunol. 1990, 2:1189-1194.
    • (1990) Int. Immunol. , vol.2 , pp. 1189-1194
    • Tomonari, K.1    Spencer, S.2
  • 42
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A., Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell 1994, 76:263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 43
    • 10744222630 scopus 로고    scopus 로고
    • Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: This is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface
    • Wooldridge L., Hutchinson S.L., Choi E.M., Lissina A., Jones E., Mirza F., Dunbar P.R., Price D.A., Cerundolo V., Sewell A.K. Anti-CD8 antibodies can inhibit or enhance peptide-MHC class I (pMHCI) multimer binding: This is paralleled by their effects on CTL activation and occurs in the absence of an interaction between pMHCI and CD8 on the cell surface. J. Immunol. 2003, 171:6650-6660.
    • (2003) J. Immunol. , vol.171 , pp. 6650-6660
    • Wooldridge, L.1    Hutchinson, S.L.2    Choi, E.M.3    Lissina, A.4    Jones, E.5    Mirza, F.6    Dunbar, P.R.7    Price, D.A.8    Cerundolo, V.9    Sewell, A.K.10
  • 46
    • 0027257445 scopus 로고
    • A kinase-independent function of Lck in potentiating antigen-specific T cell activation
    • Xu H., Littman D.R. A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 1993, 74:633-643.
    • (1993) Cell , vol.74 , pp. 633-643
    • Xu, H.1    Littman, D.R.2
  • 47
    • 0035017468 scopus 로고    scopus 로고
    • A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex
    • Xu X.N., Purbhoo M.A., Chen N., Mongkolsapaya J., Cox J.H., Meier U.C., Tafuro S., Dunbar P.R., Sewell A.K., Hourigan C.S., et al. A novel approach to antigen-specific deletion of CTL with minimal cellular activation using alpha3 domain mutants of MHC class I/peptide complex. Immunity 2001, 14:591-602.
    • (2001) Immunity , vol.14 , pp. 591-602
    • Xu, X.N.1    Purbhoo, M.A.2    Chen, N.3    Mongkolsapaya, J.4    Cox, J.H.5    Meier, U.C.6    Tafuro, S.7    Dunbar, P.R.8    Sewell, A.K.9    Hourigan, C.S.10
  • 48
    • 55449138409 scopus 로고    scopus 로고
    • Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif
    • Xu C., Gagnon E., Call M.E., Schnell J.R., Schwieters C.D., Carman C.V., Chou J.J., Wucherpfennig K.W. Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif. Cell 2008, 135:702-713.
    • (2008) Cell , vol.135 , pp. 702-713
    • Xu, C.1    Gagnon, E.2    Call, M.E.3    Schnell, J.R.4    Schwieters, C.D.5    Carman, C.V.6    Chou, J.J.7    Wucherpfennig, K.W.8
  • 49
    • 33747092261 scopus 로고    scopus 로고
    • Altered peptide ligands induce delayed CD8-T cell receptor interaction-a role for CD8 in distinguishing antigen quality
    • Yachi P.P., Ampudia J., Zal T., Gascoigne N.R. Altered peptide ligands induce delayed CD8-T cell receptor interaction-a role for CD8 in distinguishing antigen quality. Immunity 2006, 25:203-211.
    • (2006) Immunity , vol.25 , pp. 203-211
    • Yachi, P.P.1    Ampudia, J.2    Zal, T.3    Gascoigne, N.R.4
  • 51
    • 34548683241 scopus 로고    scopus 로고
    • Why is there so much CD45 on T cells?
    • Zamoyska R. Why is there so much CD45 on T cells?. Immunity 2007, 27:421-423.
    • (2007) Immunity , vol.27 , pp. 421-423
    • Zamoyska, R.1
  • 52
    • 0033808405 scopus 로고    scopus 로고
    • Modeling concurrent binding of multiple molecular species in cell adhesion
    • Zhu C., Williams T.E. Modeling concurrent binding of multiple molecular species in cell adhesion. Biophys. J. 2000, 79:1850-1857.
    • (2000) Biophys. J. , vol.79 , pp. 1850-1857
    • Zhu, C.1    Williams, T.E.2
  • 53
    • 0035986935 scopus 로고    scopus 로고
    • Measuring receptor/ligand interaction at the single-bond level: Experimental and interpretative issues
    • Zhu C., Long M., Chesla S.E., Bongrand P. Measuring receptor/ligand interaction at the single-bond level: Experimental and interpretative issues. Ann. Biomed. Eng. 2002, 30:305-314.
    • (2002) Ann. Biomed. Eng. , vol.30 , pp. 305-314
    • Zhu, C.1    Long, M.2    Chesla, S.E.3    Bongrand, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.