메뉴 건너뛰기




Volumn 13, Issue 4, 2012, Pages 523-536

Enzymatically activatable diagnostic probes

Author keywords

Molecular specificity; Multimodality; Nanoparticles; Signal to noise

Indexed keywords

CATHEPSIN D; FLUORODEOXYGLUCOSE F 18; FLUOROURACIL; GADOLINIUM; GADOLINIUM PENTETATE; GELATINASE A; GOLD NANOPARTICLE; GREEN FLUORESCENT PROTEIN; INDOCYANINE GREEN; MATRILYSIN; MATRIX METALLOPROTEINASE; QUANTUM DOT; RADIOISOTOPE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TETRAXETAN;

EID: 84857701418     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920112799436339     Document Type: Review
Times cited : (8)

References (170)
  • 1
    • 0142209343 scopus 로고    scopus 로고
    • Molecular imaging: Looking at problems, seeing solutions
    • Herschman, H. R. Molecular imaging: looking at problems, seeing solutions. Science, 2003, 302 (5645), 605-608.
    • (2003) Science , vol.302 , Issue.5645 , pp. 605-608
    • Herschman, H.R.1
  • 2
    • 33744487875 scopus 로고    scopus 로고
    • Molecular imaging in cancer
    • Weissleder, R. Molecular imaging in cancer. Science, 2006, 312 (5777), 1168-1171.
    • (2006) Science , vol.312 , Issue.5777 , pp. 1168-1171
    • Weissleder, R.1
  • 4
    • 58149185126 scopus 로고    scopus 로고
    • BRENDA, AMENDA and FRENDA the enzyme information system: New content and tools in 2009
    • Chang, A.; Scheer, M.; Grote, A.; Schomburg, I.; Schomburg, D. BRENDA, AMENDA and FRENDA the enzyme information system: new content and tools in 2009. Nucl. Acids Res., 2009, 37 (suppl. 1), D588-592.
    • (2009) Nucl. Acids Res. , vol.37 , Issue.SUPPL. 1
    • Chang, A.1    Scheer, M.2    Grote, A.3    Schomburg, I.4    Schomburg, D.5
  • 6
    • 33749017931 scopus 로고    scopus 로고
    • Cysteine cathepsins: Multifunctional enzymes in cancer
    • Mohamed, M. M.; Sloane, B. F. Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer, 2006, 6 (10), 764-775.
    • (2006) Nat. Rev. Cancer. , vol.6 , Issue.10 , pp. 764-775
    • Mohamed, M.M.1    Sloane, B.F.2
  • 8
    • 77952780489 scopus 로고    scopus 로고
    • Imaging Enzymes at Work: Metabolic Mapping by Enzyme Histochemistry
    • Van Noorden, C. J. F., Imaging Enzymes at Work: Metabolic Mapping by Enzyme Histochemistry. J. Histochem. Cytochem., 2010, 58 (6), 481-497.
    • (2010) J. Histochem. Cytochem. , vol.58 , Issue.6 , pp. 481-497
    • van Noorden, C.J.F.1
  • 10
    • 0026694313 scopus 로고
    • Enzyme immunoassay techniques an overview
    • Porstmann, T.; Kiessig, S. T. Enzyme immunoassay techniques an overview. J. Immunol. Methods, 1992, 150 (1-2), 5-21.
    • (1992) J. Immunol. Methods. , vol.150 , Issue.1-2 , pp. 5-21
    • Porstmann, T.1    Kiessig, S.T.2
  • 11
    • 0035312659 scopus 로고    scopus 로고
    • Recent advances in FRET: Distance determination in protein-DNA complexes
    • Hillisch, A.; Lorenz, M.; Diekmann, S. Recent advances in FRET: distance determination in protein-DNA complexes. Curr. Opin. Struct. Biol., 2001, 11 (2), 201-207.
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , Issue.2 , pp. 201-207
    • Hillisch, A.1    Lorenz, M.2    Diekmann, S.3
  • 12
    • 0035318612 scopus 로고    scopus 로고
    • A clearer vision for in vivo imaging
    • Weissleder, R. A clearer vision for in vivo imaging. Nat. Biotech., 2001, 19 (4), 316-317.
    • (2001) Nat. Biotech. , vol.19 , Issue.4 , pp. 316-317
    • Weissleder, R.1
  • 13
    • 0029898330 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer between blue-emitting and red-shifted excitationderivatives of the green fluorescent protein
    • Mitra, R. D.; Silva, C. M.; Youvan, D. C. Fluorescence resonance energy transfer between blue-emitting and red-shifted excitationderivatives of the green fluorescent protein. Gene, 1996, 173(1), 13-17.
    • (1996) Gene , vol.173 , Issue.1 , pp. 13-17
    • Mitra, R.D.1    Silva, C.M.2    Youvan, D.C.3
  • 14
    • 4544378666 scopus 로고    scopus 로고
    • Design of FRET-based GFP probes for detection of protease inhibitors
    • Zhang, B., Design of FRET-based GFP probes for detection of protease inhibitors. Biochem. Biophys. Res. Commun., 2004, 323(2), 674-678.
    • (2004) Biochem. Biophys. Res. Commun. , vol.323 , Issue.2 , pp. 674-678
    • Zhang, B.1
  • 15
    • 0029670262 scopus 로고    scopus 로고
    • Molecular beacons: Probes that fluoresce upon hybridization
    • Tyagi, S.; Kramer, F. R. Molecular beacons: probes that fluoresce upon hybridization. Nat. Biotech., 1996, 14(3), 303-308.
    • (1996) Nat. Biotech. , vol.14 , Issue.3 , pp. 303-308
    • Tyagi, S.1    Kramer, F.R.2
  • 16
    • 47249136607 scopus 로고    scopus 로고
    • Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA
    • Chen, A. K.; Behlke, M. A.; Tsourkas, A. Efficient cytosolic delivery of molecular beacon conjugates and flow cytometric analysis of target RNA. Nucl. Acids Res., 2008, 36(12), e69
    • (2008) Nucl. Acids Res. , vol.36 , Issue.12
    • Chen, A.K.1    Behlke, M.A.2    Tsourkas, A.3
  • 17
    • 0025099455 scopus 로고
    • Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer
    • Matayoshi, E.; Wang, G.; Krafft, G.; Erickson, J. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science, 1990, 247(4945), 954-958.
    • (1990) Science , vol.247 , Issue.4945 , pp. 954-958
    • Matayoshi, E.1    Wang, G.2    Krafft, G.3    Erickson, J.4
  • 18
    • 0029007093 scopus 로고
    • Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages
    • Reddy, V. Y.; Zhang, Q. Y.; Weiss, S. J. Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages. Proc. Natl. Acad. Sci. USA, 1995, 92(9), 3849-3853.
    • (1995) Proc. Natl. Acad. Sci. USA. , vol.92 , Issue.9 , pp. 3849-3853
    • Reddy, V.Y.1    Zhang, Q.Y.2    Weiss, S.J.3
  • 19
    • 0032951071 scopus 로고    scopus 로고
    • In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
    • Weissleder, R.; Tung, C.-H.; Mahmood, U.; Bogdanov, A. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat. Biotech.,1999, 17(4), 375-378.
    • (1999) Nat. Biotech. , vol.17 , Issue.4 , pp. 375-378
    • Weissleder, R.1    Tung, C.-H.2    Mahmood, U.3    Bogdanov, A.4
  • 21
    • 4043179911 scopus 로고    scopus 로고
    • In vivo imaging of protease activity in arthritis: A novel approach for monitoring treatment response
    • Wunder, A.; Tung, C.-H.; Mller-Ladner, U.; Weissleder, R.; Mahmood, U. In vivo imaging of protease activity in arthritis: A novel approach for monitoring treatment response. Arthritis Rheumatism, 2004, 50(8), 2459-2465.
    • (2004) Arthritis Rheumatism , vol.50 , Issue.8 , pp. 2459-2465
    • Wunder, A.1    Tung, C.-H.2    Mller-Ladner, U.3    Weissleder, R.4    Mahmood, U.5
  • 22
    • 13644263240 scopus 로고    scopus 로고
    • Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples
    • Law, B.; Hsiao, J. K.; Bugge, T. H.; Weissleder, R.; Tung, C. H. Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples. Anal. Biochem., 2005, 338(1), 151-158.
    • (2005) Anal. Biochem. , vol.338 , Issue.1 , pp. 151-158
    • Law, B.1    Hsiao, J.K.2    Bugge, T.H.3    Weissleder, R.4    Tung, C.H.5
  • 23
    • 1142306153 scopus 로고    scopus 로고
    • Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive nearinfrared reporter
    • Law, B.; Curino, A.; Bugge, T. H.; Weissleder, R.; Tung, C. H. Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive nearinfrared reporter. Chem. Biol., 2004, 11 (1), 99-106.
    • (2004) Chem. Biol. , vol.11 , Issue.1 , pp. 99-106
    • Law, B.1    Curino, A.2    Bugge, T.H.3    Weissleder, R.4    Tung, C.H.5
  • 24
    • 0036337710 scopus 로고    scopus 로고
    • Molecular Imaging of MMP Expression and Therapeutic MMP Inhibition
    • Bremer, C.; Tung, C.-H.; Weissleder, R. Molecular Imaging of MMP Expression and Therapeutic MMP Inhibition. Academic Radiol., 2002, 9 (2), S314-S315.
    • (2002) Academic Radiol , vol.9 , Issue.2
    • Bremer, C.1    Tung, C.-H.2    Weissleder, R.3
  • 26
    • 0034283034 scopus 로고    scopus 로고
    • In vivo imaging of proteolytic enzyme activity using a novel molecular reporter
    • Tung, C.-H.; Mahmood, U.; Bredow, S.; Weissleder, R., In vivo imaging of proteolytic enzyme activity using a novel molecular reporter. Cancer Res., 2000, 60(17), 4953-4958.
    • (2000) Cancer Res , vol.60 , Issue.17 , pp. 4953-4958
    • Tung, C.-H.1    Mahmood, U.2    Bredow, S.3    Weissleder, R.4
  • 29
    • 73349130028 scopus 로고    scopus 로고
    • Restriction-Enzyme-Coded Gold-Nanoparticle Probes for Multiplexed DNA Detection
    • Jang, K.-J.; Lee, H.; Jin, H.-L.; Park, Y.; Nam, J.-M., Restriction-Enzyme-Coded Gold-Nanoparticle Probes for Multiplexed DNA Detection. Small, 2009, 5 (23), 2665-2668.
    • (2009) Small , vol.5 , Issue.23 , pp. 2665-2668
    • Jang, K.-J.1    Lee, H.2    Jin, H.-L.3    Park, Y.4    Nam, J.-M.5
  • 30
    • 45249096690 scopus 로고    scopus 로고
    • Energy transfer-based multiplexed assay of proteases by using gold nanoparticle and quantum dot conjugates on a surface
    • Kim, Y.-P.; Oh, Y.-H.; Oh, E.; Ko, S.; Han, M.-K.; Kim, H.-S. Energy transfer-based multiplexed assay of proteases by using gold nanoparticle and quantum dot conjugates on a surface. Analyt. Chem., 2008, 80 (12), 4634-4641.
    • (2008) Analyt. Chem. , vol.80 , Issue.12 , pp. 4634-4641
    • Kim, Y.-P.1    Oh, Y.-H.2    Oh, E.3    Ko, S.4    Han, M.-K.5    Kim, H.-S.6
  • 31
    • 67049171034 scopus 로고    scopus 로고
    • Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation1
    • Sheth, R. A.; Tam, J. M.; Maricevich, M. A.; Josephson, L.; Mahmood, U. Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation1. Radiology, 2009, 251 (3), 813-821.
    • (2009) Radiology , vol.251 , Issue.3 , pp. 813-821
    • Sheth, R.A.1    Tam, J.M.2    Maricevich, M.A.3    Josephson, L.4    Mahmood, U.5
  • 32
    • 1642377967 scopus 로고    scopus 로고
    • A dual fluorochrome probe for imaging proteases
    • Kircher, M. F.; Weissleder, R.; Josephson, L. A dual fluorochrome probe for imaging proteases. Bioconjug. Chem., 2004, 15 (2), 242-248.
    • (2004) Bioconjug. Chem. , vol.15 , Issue.2 , pp. 242-248
    • Kircher, M.F.1    Weissleder, R.2    Josephson, L.3
  • 33
    • 0029816460 scopus 로고    scopus 로고
    • The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
    • Melo, J. V. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood, 1996, 88(7), 2375-2384.
    • (1996) Blood , vol.88 , Issue.7 , pp. 2375-2384
    • Melo, J.V.1
  • 34
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker, B. J.; Tamura, S.; Buchdunger, E.; Ohno, S.; Segal, G. M.; Fanning, S.; Zimmermann, J.; Lydon, N. B. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med., 1996, 2 (5), 561-566.
    • (1996) Nat. Med. , vol.2 , Issue.5 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4    Segal, G.M.5    Fanning, S.6    Zimmermann, J.7    Lydon, N.B.8
  • 35
    • 0036391801 scopus 로고    scopus 로고
    • The Abl Family Kinases: Mechanisms of Regulation and Signaling
    • Academic Press
    • Pendergast, A. M. In: The Abl Family Kinases: Mechanisms of Regulation and Signaling. Advances in Cancer Research, Academic Press: 2002; Vol. 85, pp 51-100.
    • (2002) Advances in Cancer Research , vol.85 , pp. 51-100
    • Pendergast, A.M.1
  • 36
    • 0036196296 scopus 로고    scopus 로고
    • Fluorescent indicators for imaging protein phosphorylation in single living cells
    • Sato, M.; Ozawa, T.; Inukai, K.; Asano, T.; Umezawa, Y. Fluorescent indicators for imaging protein phosphorylation in single living cells. Nat. Biotech., 2002, 20(3), 287-294.
    • (2002) Nat. Biotech. , vol.20 , Issue.3 , pp. 287-294
    • Sato, M.1    Ozawa, T.2    Inukai, K.3    Asano, T.4    Umezawa, Y.5
  • 37
    • 0035910074 scopus 로고    scopus 로고
    • Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
    • Zhang, J.; Ma, Y.; Taylor, S. S.; Tsien, R. Y. Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proc.Natl. Acad. Sci.USA, 2001, 98(26), 14997-15002.
    • (2001) Proc.Natl. Acad. Sci.USA. , vol.98 , Issue.26 , pp. 14997-15002
    • Zhang, J.1    Ma, Y.2    Taylor, S.S.3    Tsien, R.Y.4
  • 39
    • 0344443386 scopus 로고    scopus 로고
    • Versatile Fluorescence Probes of Protein Kinase Activity
    • Shults, M. D.; Imperiali, B. Versatile Fluorescence Probes of Protein Kinase Activity. J. Am. Chem. Soc., 2003, 125(47), 14248-14249.
    • (2003) J. Am. Chem. Soc. , vol.125 , Issue.47 , pp. 14248-14249
    • Shults, M.D.1    Imperiali, B.2
  • 40
    • 18744408814 scopus 로고    scopus 로고
    • A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates
    • Shults, M. D.; Janes, K. A.; Lauffenburger, D. A.; Imperiali, B. A multiplexed homogeneous fluorescence-based assay for protein kinase activity in cell lysates. Nat. Meth., 2005, 2 (4), 277-284.
    • (2005) Nat. Meth. , vol.2 , Issue.4 , pp. 277-284
    • Shults, M.D.1    Janes, K.A.2    Lauffenburger, D.A.3    Imperiali, B.4
  • 41
    • 0032859927 scopus 로고    scopus 로고
    • Localized measurement of kinase activation in oocytes of Xenopus laevis
    • Lee, C.-L.; Linton, J.; Soughayer, J. S.; Sims, C. E.; Allbritton, N. L. Localized measurement of kinase activation in oocytes of Xenopus laevis. Nat. Biotech., 1999, 17 (8), 759-762.
    • (1999) Nat. Biotech. , vol.17 , Issue.8 , pp. 759-762
    • Lee, C.-L.1    Linton, J.2    Soughayer, J.S.3    Sims, C.E.4    Allbritton, N.L.5
  • 42
    • 0037345703 scopus 로고    scopus 로고
    • N-Ac-DEVD-N' Äò-(Polyfluorobenzoyl)' àíR110:' Äâ Novel Cell-Permeable Fluorogenic Caspase Substrates for the Detection of Caspase Activity and Apoptosis
    • Zhang, H.-Z.; Kasibhatla, S.; Guastella, J.; Tseng, B.; Drewe, J.; Cai, S. X. N-Ac-DEVD-N' Äò-(Polyfluorobenzoyl)' àíR110:' Äâ Novel Cell-Permeable Fluorogenic Caspase Substrates for the Detection of Caspase Activity and Apoptosis. Bioconjug. Chem., 2003, 14 (2), 458-463.
    • (2003) Bioconjug. Chem. , vol.14 , Issue.2 , pp. 458-463
    • Zhang, H.-Z.1    Kasibhatla, S.2    Guastella, J.3    Tseng, B.4    Drewe, J.5    Cai, S.X.6
  • 43
    • 0029913726 scopus 로고    scopus 로고
    • Characterization of human adenovirus proteinase activity in disrupted virus particles
    • McGrath, W. J.; Abola, A. P.; Toledo, D. L.; Brown, M. T.; Mangel, W. F. Characterization of human adenovirus proteinase activity in disrupted virus particles. Virology, 1996, 217 (1), 131-138.
    • (1996) Virology , vol.217 , Issue.1 , pp. 131-138
    • McGrath, W.J.1    Abola, A.P.2    Toledo, D.L.3    Brown, M.T.4    Mangel, W.F.5
  • 44
    • 28844463521 scopus 로고    scopus 로고
    • Development of watersoluble far-red fluorogenic dyes for enzyme sensing
    • Ho, N.-H.; Weissleder, R.; Tung, C.-H. Development of watersoluble far-red fluorogenic dyes for enzyme sensing. Tetrahedron, 2006, 62(4), 578-585.
    • (2006) Tetrahedron , vol.62 , Issue.4 , pp. 578-585
    • Ho, N.-H.1    Weissleder, R.2    Tung, C.-H.3
  • 46
    • 77749297971 scopus 로고    scopus 로고
    • Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
    • Olson, E. S.; Jiang, T.; Aguilera, T. A.; Nguyen, Q. T.; Ellies, L. G.; Scadeng, M.; Tsien, R. Y. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc. Natl. Acad. Sci. USA, 2010, 107(9), 4311-4316.
    • (2010) Proc. Natl. Acad. Sci. USA. , vol.107 , Issue.9 , pp. 4311-4316
    • Olson, E.S.1    Jiang, T.2    Aguilera, T.A.3    Nguyen, Q.T.4    Ellies, L.G.5    Scadeng, M.6    Tsien, R.Y.7
  • 48
    • 61749094550 scopus 로고    scopus 로고
    • Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon
    • Scherer, R. L.; VanSaun, M. N.; McIntyre, J. O.; Matrisian, L. M. Optical imaging of matrix metalloproteinase-7 activity in vivo using a proteolytic nanobeacon. Mol. Imaging, 2008, 7(3), 118-131.
    • (2008) Mol. Imaging. , vol.7 , Issue.3 , pp. 118-131
    • Scherer, R.L.1    Vansaun, M.N.2    McIntyre, J.O.3    Matrisian, L.M.4
  • 49
    • 77749254873 scopus 로고    scopus 로고
    • Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
    • Nguyen, Q. T.; Olson, E. S.; Aguilera, T. A.; Jiang, T.; Scadeng, M.; Ellies, L. G.; Tsien, R. Y. Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc. Natl. Acad. Sci. USA, 2010, 107(9), 4317-4322.
    • (2010) Proc. Natl. Acad. Sci. USA. , vol.107 , Issue.9 , pp. 4317-4322
    • Nguyen, Q.T.1    Olson, E.S.2    Aguilera, T.A.3    Jiang, T.4    Scadeng, M.5    Ellies, L.G.6    Tsien, R.Y.7
  • 50
    • 33749682476 scopus 로고    scopus 로고
    • Protease-modulated cellular uptake of quantum dots
    • Zhang, Y.; So, M. K.; Rao, J. Protease-modulated cellular uptake of quantum dots. Nano. Lett., 2006, 6(9), 1988-1992.
    • (2006) Nano. Lett. , vol.6 , Issue.9 , pp. 1988-1992
    • Zhang, Y.1    So, M.K.2    Rao, J.3
  • 51
    • 52649169324 scopus 로고    scopus 로고
    • Protease-triggered unveiling of bioactive nanoparticles
    • Harris, T. J.; Maltzahn, G. Protease-triggered unveiling of bioactive nanoparticles. Small, 2008, 4 (9), 1307-1312.
    • (2008) Small , vol.4 , Issue.9 , pp. 1307-1312
    • Harris, T.J.1    Maltzahn, G.2
  • 52
    • 0023124097 scopus 로고
    • Firefly luciferase gene: Structure and expression in mammalian cells
    • de Wet, J. R.; Wood, K. V.; DeLuca, M.; Helinski, D. R.; Subramani, S. Firefly luciferase gene: structure and expression in mammalian cells. Mol. Cell. Biol., 1987, 7(2), 725-737.
    • (1987) Mol. Cell. Biol. , vol.7 , Issue.2 , pp. 725-737
    • de Wet, J.R.1    Wood, K.V.2    Deluca, M.3    Helinski, D.R.4    Subramani, S.5
  • 53
    • 0029618035 scopus 로고
    • Monitoring gene expression of Salmonella inside mammalian cells: Comparison of luciferase and [beta]- galactosidase fusion systems
    • Pfeifer, C. G.; Finlay, B. B. Monitoring gene expression of Salmonella inside mammalian cells: comparison of luciferase and [beta]- galactosidase fusion systems. J. Microbiol., Methods, 1995, 24 (2), 155-164.
    • (1995) J. Microbiol., Methods. , vol.24 , Issue.2 , pp. 155-164
    • Pfeifer, C.G.1    Finlay, B.B.2
  • 54
    • 0036405345 scopus 로고    scopus 로고
    • Advances in in vivo bioluminescence imaging of gene expression
    • Contag, C. H.; Bachmann, M. H. Advances in in vivo bioluminescence imaging of gene expression. Annu. Rev. Biomed. Eng., 2003, 4 (1), 235-260.
    • (2003) Annu. Rev. Biomed. Eng. , vol.4 , Issue.1 , pp. 235-260
    • Contag, C.H.1    Bachmann, M.H.2
  • 56
    • 0023897416 scopus 로고
    • A new type of ultrasensitive bioluminogenic enzyme substrates. I. Enzyme substrates with D-luciferin as leaving group
    • Miska, W.; Geiger, R. A new type of ultrasensitive bioluminogenic enzyme substrates. I. Enzyme substrates with D-luciferin as leaving group. Biol. Chem. Hoppe Seyler, 1988, 369 (5), 407-11.
    • (1988) Biol. Chem. Hoppe Seyler. , vol.369 , Issue.5 , pp. 407-411
    • Miska, W.1    Geiger, R.2
  • 57
    • 0028095409 scopus 로고
    • Synthesis and Characterization of a Bioluminogenic Substrate for [alpha]-Chymotrypsin
    • Monsees, T.; Miska, W.; Geiger, R. Synthesis and Characterization of a Bioluminogenic Substrate for [alpha]-Chymotrypsin. Analyt. Biochem., 1994, 221 (2), 329-334.
    • (1994) Analyt. Biochem. , vol.221 , Issue.2 , pp. 329-334
    • Monsees, T.1    Miska, W.2    Geiger, R.3
  • 59
    • 0344142396 scopus 로고    scopus 로고
    • Emerging roles of caspase-3 in apoptosis
    • Porter, A. G.; Janicke, R. U. Emerging roles of caspase-3 in apoptosis. Cell Death Differ., 1999, 6 (2), 99-104.
    • (1999) Cell Death Differ , vol.6 , Issue.2 , pp. 99-104
    • Porter, A.G.1    Janicke, R.U.2
  • 61
    • 19444363758 scopus 로고    scopus 로고
    • In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis
    • Shah, K.; Tung, C.-H.; Breakefield, X. O.; Weissleder, R. In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis. Mol. Ther., 2005, 11(6), 926-931.
    • (2005) Mol. Ther. , vol.11 , Issue.6 , pp. 926-931
    • Shah, K.1    Tung, C.-H.2    Breakefield, X.O.3    Weissleder, R.4
  • 62
    • 33746300562 scopus 로고    scopus 로고
    • In vivo testing of Renilla luciferase substrate analogs in an orthotopic murine model of human glioblastoma
    • Otto-Duessel, M.; Khankaldyyan, V.; Gonzalez-Gomez, I.; Jensen, M. C.; Laug, W. E.; Rosol, M. In vivo testing of Renilla luciferase substrate analogs in an orthotopic murine model of human glioblastoma. Mol. Imaging, 2006, 5(2), 57-64.
    • (2006) Mol. Imaging. , vol.5 , Issue.2 , pp. 57-64
    • Otto-Duessel, M.1    Khankaldyyan, V.2    Gonzalez-Gomez, I.3    Jensen, M.C.4    Laug, W.E.5    Rosol, M.6
  • 63
    • 0027027361 scopus 로고
    • A new ultrasensitive bioluminogenic enzyme substrate for betagalactosidase
    • Geiger, R.; Schneider, E.; Wallenfels, K.; Miska, W. A new ultrasensitive bioluminogenic enzyme substrate for betagalactosidase. Biol. Chem. Hoppe Seyler, 1992, 373(12), 1187-91.
    • (1992) Biol. Chem. Hoppe Seyler. , vol.373 , Issue.12 , pp. 1187-1191
    • Geiger, R.1    Schneider, E.2    Wallenfels, K.3    Miska, W.4
  • 64
    • 33645278110 scopus 로고    scopus 로고
    • Luminescent imaging of [beta]-galactosidase activity in living subjects using sequential reporter-enzyme luminescence
    • Wehrman, T. S.; von Degenfeld, G.; Krutzik, P. O.; Nolan, G. P.; Blau, H. M. Luminescent imaging of [beta]-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nat. Meth., 2006, 3(4), 295-301.
    • (2006) Nat. Meth. , vol.3 , Issue.4 , pp. 295-301
    • Wehrman, T.S.1    von Degenfeld, G.2    Krutzik, P.O.3    Nolan, G.P.4    Blau, H.M.5
  • 65
    • 74049159611 scopus 로고    scopus 로고
    • Imaging β-galactosidase activity in vivo using sequential reporter-enzyme luminescence
    • Degenfeld, G.; Wehrman, T. S.; Blau, H. M. Imaging β-galactosidase activity in vivo using sequential reporter-enzyme luminescence. Methods Mol. Biol., 2009, 574, 249-259.
    • (2009) Methods Mol. Biol. , vol.574 , pp. 249-259
    • Degenfeld, G.1    Wehrman, T.S.2    Blau, H.M.3
  • 67
    • 33644854853 scopus 로고    scopus 로고
    • Selfilluminating quantum dot conjugates for in vivo imaging
    • So, M.-K.; Xu, C.; Loening, A. M.; Gambhir, S. S.; Rao, J. Selfilluminating quantum dot conjugates for in vivo imaging. Nat. Biotech., 2006, 24 (3), 339-343.
    • (2006) Nat. Biotech. , vol.24 , Issue.3 , pp. 339-343
    • So, M.-K.1    Xu, C.2    Loening, A.M.3    Gambhir, S.S.4    Rao, J.5
  • 68
    • 34447249005 scopus 로고    scopus 로고
    • Quantum dot/bioluminescence resonance energy transfer based highly sensitive detection of proteases13
    • Yao, H.; Zhang, Y.; Xiao, F.; Xia, Z.; Rao, J. Quantum dot/bioluminescence resonance energy transfer based highly sensitive detection of proteases13. Angewandte Chemie Intl. Ed, 2007, 46 (23), 4346-4349.
    • (2007) Angewandte Chemie Intl. Ed. , vol.46 , Issue.23 , pp. 4346-4349
    • Yao, H.1    Zhang, Y.2    Xiao, F.3    Xia, Z.4    Rao, J.5
  • 69
    • 72149096051 scopus 로고    scopus 로고
    • Bioluminescent nanosensors for protease detection based upon gold nanoparticle-luciferase conjugates
    • Kim, Y. P.; Daniel, W. L.; Xia, Z.; Xie, H.; Mirkin, C. A.; Rao, J. Bioluminescent nanosensors for protease detection based upon gold nanoparticle-luciferase conjugates. Chem. Commun., (Camb) 2010, 46 (1), 76-78.
    • (2010) Chem. Commun., (Camb). , vol.46 , Issue.1 , pp. 76-78
    • Kim, Y.P.1    Daniel, W.L.2    Xia, Z.3    Xie, H.4    Mirkin, C.A.5    Rao, J.6
  • 70
    • 77951930465 scopus 로고    scopus 로고
    • Radionuclide imaging of myocardial metabolism
    • Peterson, L. R.; Gropler, R. J. Radionuclide imaging of myocardial metabolism. Circ. Cardiovasc. Imag., 2010, 3(2), 211-222.
    • (2010) Circ. Cardiovasc. Imag. , vol.3 , Issue.2 , pp. 211-222
    • Peterson, L.R.1    Gropler, R.J.2
  • 71
    • 34547782850 scopus 로고    scopus 로고
    • Axillary lymph node metastases detection with 99mtc-sestamibi scintimammography in patients with breast cancer undergoing curative surgery
    • Lumachi, F.; Ferretti, G.; Povolato, M.; Bui, F.; Cecchin, D.; Marzola, M. C.; Zucchetta, P.; Basso, U. Axillary lymph node metastases detection with 99mtc-sestamibi scintimammography in patients with breast cancer undergoing curative surgery. Anticancer Res., 2007, 27 (4C), 2949-2952.
    • (2007) Anticancer Res , vol.27 , Issue.4 C , pp. 2949-2952
    • Lumachi, F.1    Ferretti, G.2    Povolato, M.3    Bui, F.4    Cecchin, D.5    Marzola, M.C.6    Zucchetta, P.7    Basso, U.8
  • 72
    • 0035708631 scopus 로고    scopus 로고
    • From tumor biology to clinical PET: A review of positron emission tomography (PET) in oncology
    • Kubota, K. From tumor biology to clinical PET: A review of positron emission tomography (PET) in oncology. Annal. Nuclear Med., 2001, 15(6), 471-486.
    • (2001) Annal. Nuclear Med. , vol.15 , Issue.6 , pp. 471-486
    • Kubota, K.1
  • 73
    • 44849101473 scopus 로고    scopus 로고
    • Atherosclerosis inflammation imaging with 18F-FDG PET: Carotid, Iliac, and femoral uptake reproducibility, quantification methods, and recommendations
    • Rudd, J. H. F.; Myers, K. S.; Bansilal, S.; Machac, J.; Pinto, C. A.; Tong, C.; Rafique, A.; Hargeaves, R.; Farkouh, M.; Fuster, V.; Fayad, Z. A. Atherosclerosis inflammation imaging with 18F-FDG PET: Carotid, Iliac, and femoral uptake reproducibility, quantification methods, and recommendations. J. Nuclear Med., 2008, 49(6), 871-878.
    • (2008) J. Nuclear Med. , vol.49 , Issue.6 , pp. 871-878
    • Rudd, J.H.F.1    Myers, K.S.2    Bansilal, S.3    Machac, J.4    Pinto, C.A.5    Tong, C.6    Rafique, A.7    Hargeaves, R.8    Farkouh, M.9    Fuster, V.10    Fayad, Z.A.11
  • 75
    • 0036156598 scopus 로고    scopus 로고
    • Whole-body FDG-PET imaging in the management of patients with cancer
    • Hustinx, R.; BÈnard, F.; Alavi, A. Whole-body FDG-PET imaging in the management of patients with cancer. Semin. Nuclear Med., 2002, 32(1), 35-46.
    • (2002) Semin. Nuclear Med. , vol.32 , Issue.1 , pp. 35-46
    • Hustinx, R.1    Bènard, F.2    Alavi, A.3
  • 76
    • 0036156690 scopus 로고    scopus 로고
    • Guest editorial: The conception of FDGPET imaging
    • Alavi, A.; Reivich, M. Guest editorial: The conception of FDGPET imaging. Semin. Nuclear Med., 2002, 32(1), 2-5.
    • (2002) Semin. Nuclear Med. , vol.32 , Issue.1 , pp. 2-5
    • Alavi, A.1    Reivich, M.2
  • 77
    • 33746078149 scopus 로고    scopus 로고
    • 18F-FDG PET as a candidate for "qualified biomarker": Functional assessment of treatment response in oncology
    • Larson, S. M.; Schwartz, L. H. 18F-FDG PET as a candidate for "qualified biomarker": functional assessment of treatment response in oncology. J. Nuclear Med., 2006, 47(6), 901-903.
    • (2006) J. Nuclear Med. , vol.47 , Issue.6 , pp. 901-903
    • Larson, S.M.1    Schwartz, L.H.2
  • 78
    • 0019960281 scopus 로고
    • Quantitative autoradiographic mapping of herpes simplex virus encephalitis with a radiolabeled antiviral drug
    • Saito, Y.; Price, R.; Rottenberg, D.; Fox, J.; Su, T.; Watanabe, K.; Philips, F. Quantitative autoradiographic mapping of herpes simplex virus encephalitis with a radiolabeled antiviral drug. Science, 1982, 217(4565), 1151-1153.
    • (1982) Science , vol.217 , Issue.4565 , pp. 1151-1153
    • Saito, Y.1    Price, R.2    Rottenberg, D.3    Fox, J.4    Su, T.5    Watanabe, K.6    Philips, F.7
  • 79
    • 0022485359 scopus 로고
    • Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
    • Moolten, F. L. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res., 1986, 46(10), 5276-5281.
    • (1986) Cancer Res , vol.46 , Issue.10 , pp. 5276-5281
    • Moolten, F.L.1
  • 80
    • 0021843802 scopus 로고
    • Murine mammary FM3A carcinoma cells transformed with the herpes simplex virus type 1 thymidine kinase gene are highly sensitive to the growth-inhibitory properties of (E)-5-(2-bromovinyl)-2'- deoxyuridine and related compounds
    • Balzarini, J.; de Clercq, E.; Ayusawa, D.; Seno, T. Murine mammary FM3A carcinoma cells transformed with the herpes simplex virus type 1 thymidine kinase gene are highly sensitive to the growth-inhibitory properties of (E)-5-(2-bromovinyl)-2'- deoxyuridine and related compounds. FEBS Lett., 1985, 185 (1), 95-100.
    • (1985) FEBS Lett , vol.185 , Issue.1 , pp. 95-100
    • Balzarini, J.1    de Clercq, E.2    Ayusawa, D.3    Seno, T.4
  • 81
    • 9544242826 scopus 로고    scopus 로고
    • Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy
    • Tjuvajev, J. G.; Finn, R.; Watanabe, K.; Joshi, R.; Oku, T.; Kennedy, J.; Beattie, B.; Koutcher, J.; Larson, S.; Blasberg, R. G. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy. Cancer Res., 1996, 56(18), 4087-4095.
    • (1996) Cancer Res , vol.56 , Issue.18 , pp. 4087-4095
    • Tjuvajev, J.G.1    Finn, R.2    Watanabe, K.3    Joshi, R.4    Oku, T.5    Kennedy, J.6    Beattie, B.7    Koutcher, J.8    Larson, S.9    Blasberg, R.G.10
  • 83
    • 33747125144 scopus 로고    scopus 로고
    • Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer
    • Wang, H.-E.; Yu, H.-M.; Liu, R.-S.; Lin, M.; Gelovani, J. G.; Hwang, J.-J.; Wei, H.-J.; Deng, W.-P. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer. J. Nuclear Med., 2006, 47(7), 1161-1171.
    • (2006) J. Nuclear Med. , vol.47 , Issue.7 , pp. 1161-1171
    • Wang, H.-E.1    Yu, H.-M.2    Liu, R.-S.3    Lin, M.4    Gelovani, J.G.5    Hwang, J.-J.6    Wei, H.-J.7    Deng, W.-P.8
  • 85
    • 0023951483 scopus 로고
    • Regulation of human thymidine kinase during the cell cycle
    • Sherley, J. L.; Kelly, T. J. Regulation of human thymidine kinase during the cell cycle. J. Biol. Chem., 1988, 263(17), 8350-8358.
    • (1988) J. Biol. Chem. , vol.263 , Issue.17 , pp. 8350-8358
    • Sherley, J.L.1    Kelly, T.J.2
  • 87
    • 0030271612 scopus 로고    scopus 로고
    • Assessment of the biodistribution and metabolism of 5-fluorouracil as monitored by 18F PET and 19F MRI
    • Gunnar, B.; Matthias, E. B.; Uwe, H.; Ludwig, G.; Walter, J. L. Assessment of the biodistribution and metabolism of 5-fluorouracil as monitored by 18F PET and 19F MRI: A comparative animal study. Nuclear Med. Biol., 1996, 23 (7), 897-906.
    • (1996) A Comparative Animal Study. Nuclear Med. Biol. , vol.23 , Issue.7 , pp. 897-906
    • Gunnar, B.1    Matthias, E.B.2    Uwe, H.3    Ludwig, G.4    Walter, J.L.5
  • 88
    • 33947264285 scopus 로고    scopus 로고
    • Evaluation of chemical, physical, and biologic properties of tumor-targeting radioiodinated quinazolinone derivative
    • Wang, K.; Kirichian, A. M.; Al Aowad, A. F.; Adelstein, S. J.; Kassis, A. I. Evaluation of chemical, physical, and biologic properties of tumor-targeting radioiodinated quinazolinone derivative. Bioconjug. Chem., 2007, 18(3), 754-764.
    • (2007) Bioconjug. Chem. , vol.18 , Issue.3 , pp. 754-764
    • Wang, K.1    Kirichian, A.M.2    Al, A.A.F.3    Adelstein, S.J.4    Kassis, A.I.5
  • 89
    • 0036009653 scopus 로고    scopus 로고
    • Synthesis and biologic evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated insolubilization therapy
    • Ho, N.-h.; Harapanhalli, R. S.; Dahman, B. A.; Chen, K.; Wang, K.; Adelstein, S. J.; Kassis, A. I. Synthesis and biologic evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated insolubilization therapy. Bioconjug. Chem., 2002, 13 (2), 357-364.
    • (2002) Bioconjug. Chem. , vol.13 , Issue.2 , pp. 357-364
    • Ho, N.-H.1    Harapanhalli, R.S.2    Dahman, B.A.3    Chen, K.4    Wang, K.5    Adelstein, S.J.6    Kassis, A.I.7
  • 93
    • 34648822432 scopus 로고    scopus 로고
    • Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging
    • Xu, H.; Baidoo, K.; Gunn, A. J.; Boswell, C. A.; Milenic, D. E.; Choyke, P. L.; Brechbiel, M. W. Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging. J. Med. Chem., 2007, 50 (19), 4759-4765.
    • (2007) J. Med. Chem. , vol.50 , Issue.19 , pp. 4759-4765
    • Xu, H.1    Baidoo, K.2    Gunn, A.J.3    Boswell, C.A.4    Milenic, D.E.5    Choyke, P.L.6    Brechbiel, M.W.7
  • 94
    • 73349086909 scopus 로고    scopus 로고
    • Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe
    • [Lee, H.; Akers, W. J.; Cheney, P. P.; Edwards, W. B.; Liang, K.; Culver, J. P.; Achilefu, S. Complementary optical and nuclear imaging of caspase-3 activity using combined activatable and radio-labeled multimodality molecular probe. J. Biomed. Optics, 2009, 14(4), 040507.
    • (2009) J. Biomed. Optics. , vol.14 , Issue.4 , pp. 040507
    • Lee, H.1    Akers, W.J.2    Cheney, P.P.3    Edwards, W.B.4    Liang, K.5    Culver, J.P.6    Achilefu, S.7
  • 97
    • 0037057683 scopus 로고    scopus 로고
    • Helicobacter pylori Infection
    • Suerbaum, S.; Michetti, P. Helicobacter pylori Infection. N. Engl. J. Med., 2002, 347 (15), 1175-1186.
    • (2002) N. Engl. J. Med. , vol.347 , Issue.15 , pp. 1175-1186
    • Suerbaum, S.1    Michetti, P.2
  • 98
    • 0023247079 scopus 로고
    • Campylobacter pyloridis gastritis I: Detection of urease as a marker of bacterial colonization and gastritis
    • Hazell, S. L.; Borody, T. J.; Gal, A.; Lee, A. Campylobacter pyloridis gastritis I: Detection of urease as a marker of bacterial colonization and gastritis. Am. J. Gastroenterol., 1987, 82 (4), 292-6.
    • (1987) Am. J. Gastroenterol. , vol.82 , Issue.4 , pp. 292-296
    • Hazell, S.L.1    Borody, T.J.2    Gal, A.3    Lee, A.4
  • 99
    • 0023850584 scopus 로고
    • Carbon-14 urea breath test forthe diagnosis of Campylobacter pylori associated gastritis
    • Marshall, B. J.; Surveyor, I. Carbon-14 urea breath test forthe diagnosis of Campylobacter pylori associated gastritis. J. Nucl. Med., 1988, 29(1), 11-16.
    • (1988) J. Nucl. Med. , vol.29 , Issue.1 , pp. 11-16
    • Marshall, B.J.1    Surveyor, I.2
  • 101
    • 0032470377 scopus 로고    scopus 로고
    • Magnetic field dependence of solvent proton relaxation by solute dysprosium(III) complexes
    • Kellar, K.E.P.; Fossheim, S.L.M.P.; Koenig, S.H.P. Magnetic field dependence of solvent proton relaxation by solute dysprosium(III) complexes. Invest. Radiol., 1998, 33(11),835-840
    • (1998) Invest. Radiol. , vol.33 , Issue.11 , pp. 835-840
    • Kellar, K.E.P.1    Fossheim, S.L.M.P.2    Koenig, S.H.P.3
  • 102
    • 0030843681 scopus 로고    scopus 로고
    • A "Smart" magnetic resonance imaging agent that reports on specific enzymatic activity
    • [Moats, R. A.; Fraser, S. E.; Meade, T. J. A "Smart" magnetic resonance imaging agent that reports on specific enzymatic activity. Angewandte Chemie Intl. Ed. Eng., 1997, 36 (7), 726-728.
    • (1997) Angewandte Chemie Intl. Ed. Eng. , vol.36 , Issue.7 , pp. 726-728
    • Moats, R.A.1    Fraser, S.E.2    Meade, T.J.3
  • 104
    • 0038277090 scopus 로고    scopus 로고
    • Magnetic resonance molecular imaging of the HER-2/neu receptor
    • Artemov, D.; Mori, N.; Ravi, R.; Bhujwalla, Z. M. Magnetic resonance molecular imaging of the HER-2/neu receptor. Cancer Res., 2003, 63 (11), 2723-2727.
    • (2003) Cancer Res , vol.63 , Issue.11 , pp. 2723-2727
    • Artemov, D.1    Mori, N.2    Ravi, R.3    Bhujwalla, Z.M.4
  • 105
    • 0034090669 scopus 로고    scopus 로고
    • Sulfonamide-Functionalized Gadolinium DTPA Complexes as Possible Contrast Agents for MRI: A Relaxometric Investigation
    • Anelli, P. L.; Bertini, I.; Fragai, M.; Lattuada, L.; Luchinat, C.; Parigi, G. Sulfonamide-Functionalized Gadolinium DTPA Complexes as Possible Contrast Agents for MRI: A Relaxometric Investigation. Euro. J. Inorg., Chem., 2000, 2000(4), 625-630.
    • (2000) Euro. J. Inorg., Chem. , vol.2000 , Issue.4 , pp. 625-630
    • Anelli, P.L.1    Bertini, I.2    Fragai, M.3    Lattuada, L.4    Luchinat, C.5    Parigi, G.6
  • 106
    • 38849101761 scopus 로고    scopus 로고
    • Gd3+-based magnetic resonance imaging contrast agent sensitive to beta-galactosidase activity utilizing a receptor-induced magnetization enhancement (RIME) phenomenon
    • Hanaoka, K.; Kikuchi, K.; Terai, T.; Komatsu, T.; Nagano, T. A Gd3+-based magnetic resonance imaging contrast agent sensitive to beta-galactosidase activity utilizing a receptor-induced magnetization enhancement (RIME) phenomenon. Chem. A Euro. J., 2008, 14 (3), 987-995.
    • (2008) Chem. a Euro. J. , vol.14 , Issue.3 , pp. 987-995
    • Hanaoka, K.1    Kikuchi, K.2    Terai, T.3    Komatsu, T.4    Nagano, T.A.5
  • 107
    • 41149109091 scopus 로고    scopus 로고
    • Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury
    • Nahrendorf, M.; Sosnovik, D.; Chen, J. W.; Panizzi, P.; Figueiredo, J.-L.; Aikawa, E.; Libby, P.; Swirski, F. K.; Weissleder, R. Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury. Circulation, 2008, 117(9), 1153-1160.
    • (2008) Circulation , vol.117 , Issue.9 , pp. 1153-1160
    • Nahrendorf, M.1    Sosnovik, D.2    Chen, J.W.3    Panizzi, P.4    Figueiredo, J.-L.5    Aikawa, E.6    Libby, P.7    Swirski, F.K.8    Weissleder, R.9
  • 108
    • 18844451778 scopus 로고    scopus 로고
    • DTPA-bisamide-based MR sensor agents for peroxidase imaging
    • Querol, M.; Chen, J. W.; Weissleder, R.; Bogdanov, A. DTPA-bisamide-based MR sensor agents for peroxidase imaging. Organic Lett., 2005, 7 (9), 1719-1722.
    • (2005) Organic Lett , vol.7 , Issue.9 , pp. 1719-1722
    • Querol, M.1    Chen, J.W.2    Weissleder, R.3    Bogdanov, A.4
  • 109
    • 0002808589 scopus 로고    scopus 로고
    • Oligomerization of paramagnetic substrates result in signal amplification and can be used for mr imaging of molecular targets
    • Bogdanov Jr, A.; Matuszewski, L.; Bremer, C.; Petrovsky, A.; Weissleder, R. Oligomerization of paramagnetic substrates result in signal amplification and can be used for mr imaging of molecular targets. Mol. Imaging, 2002, 1 (1), 16-23.
    • (2002) Mol. Imaging. , vol.1 , Issue.1 , pp. 16-23
    • Bogdanov, A.1    Matuszewski, L.2    Bremer, C.3    Petrovsky, A.4    Weissleder, R.5
  • 110
    • 0035800420 scopus 로고    scopus 로고
    • Enzyme-activated Gd3+ magnetic resonance imaging contrast agents with a prominentz receptor-induced magnetization enhancement
    • Nivorozhkin, A. L.; Kolodziej, A. F.; Caravan, P.; Greenfield, M. T.; Lauffer, R. B.; McMurry, T. J. Enzyme-activated Gd3+ magnetic resonance imaging contrast agents with a prominentz receptor-induced magnetization enhancement. Angew. Chemie Intl. Edi., 2001, 40(15), 2903-2906.
    • (2001) Angew. Chemie Intl. Edi. , vol.40 , Issue.15 , pp. 2903-2906
    • Nivorozhkin, A.L.1    Kolodziej, A.F.2    Caravan, P.3    Greenfield, M.T.4    Lauffer, R.B.5    McMurry, T.J.6
  • 111
    • 41849109453 scopus 로고    scopus 로고
    • Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis
    • Chen, J. W.; Breckwoldt, M. O.; Aikawa, E.; Chiang, G.; Weissleder, R. Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain, 2008, 131(4), 1123-1133.
    • (2008) Brain , vol.131 , Issue.4 , pp. 1123-1133
    • Chen, J.W.1    Breckwoldt, M.O.2    Aikawa, E.3    Chiang, G.4    Weissleder, R.5
  • 113
    • 74849102977 scopus 로고    scopus 로고
    • Activatable Magnetic Resonance Imaging Agents for Myeloperoxidase Sensing: Mechanism of Activation, Stability, and Toxicity
    • Rodriguez, E.; Nilges, M.; Weissleder, R.; Chen, J. W. Activatable Magnetic Resonance Imaging Agents for Myeloperoxidase Sensing: Mechanism of Activation, Stability, and Toxicity. J. Am. Chem. Soc., 2009, 132 (1), 168-177.
    • (2009) J. Am. Chem. Soc. , vol.132 , Issue.1 , pp. 168-177
    • Rodriguez, E.1    Nilges, M.2    Weissleder, R.3    Chen, J.W.4
  • 114
    • 0036794367 scopus 로고    scopus 로고
    • Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations
    • Aime, S.; Cabella, C.; Colombatto, S.; Crich, S. G.; Gianolio, E.; Maggioni, F. Insights into the use of paramagnetic Gd(III) complexes in MR-molecular imaging investigations. J. Magn.Resonance Imaging, 2002, 16(4), 394-406.
    • (2002) J. Magn.Resonance Imaging. , vol.16 , Issue.4 , pp. 394-406
    • Aime, S.1    Cabella, C.2    Colombatto, S.3    Crich, S.G.4    Gianolio, E.5    Maggioni, F.6
  • 116
    • 55749111198 scopus 로고    scopus 로고
    • Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model
    • eogon; bska
    • Lebel, R.; Jastrz, B.; eogon; bska; Therriault, H.; Cournoyer, M.-M.; McIntyre, J. O.; Escher, E.; Neugebauer, W.; Paquette, B.; Lepage, M. Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model. Magn. Resonance Med., 2008, 60 (5), 1056-1065.
    • (2008) Magn. Resonance Med. , vol.60 , Issue.5 , pp. 1056-1065
    • Lebel, R.1    Jastrz, B.2
  • 118
    • 0033766573 scopus 로고    scopus 로고
    • Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST)
    • Ward, K. M.; Balaban, R. S. Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST). Magnetic Resonance Med., 2000, 44 (5), 799-802.
    • (2000) Magnetic Resonance Med , vol.44 , Issue.5 , pp. 799-802
    • Ward, K.M.1    Balaban, R.S.2
  • 119
    • 1642351484 scopus 로고    scopus 로고
    • Ln(III)-DOTAMGly complexes: A versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications
    • Terreno, E.; Castelli, D. D.; Cravotto, G.; Milone, L.; Aime, S. Ln(III)-DOTAMGly complexes: A versatile series to assess the determinants of the efficacy of paramagnetic chemical exchange saturation transfer agents for magnetic resonance imaging applications. Invest. Radiol., 2004, 39(4), 235-243.
    • (2004) Invest. Radiol. , vol.39 , Issue.4 , pp. 235-243
    • Terreno, E.1    Castelli, D.D.2    Cravotto, G.3    Milone, L.4    Aime, S.5
  • 121
    • 0036366267 scopus 로고    scopus 로고
    • Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging
    • Aime, S.; Anelli, L.; Botta, M.; Brocchetta, M.; Canton, S.; Fedeli, F.; Gianolio, E.; Terreno, E. Relaxometric evaluation of novel manganese(II) complexes for application as contrast agents in magnetic resonance imaging. J. Biol. Inorg. Chem., 2002, 7 (1-2), 58-67.
    • (2002) J. Biol. Inorg. Chem. , vol.7 , Issue.1-2 , pp. 58-67
    • Aime, S.1    Anelli, L.2    Botta, M.3    Brocchetta, M.4    Canton, S.5    Fedeli, F.6    Gianolio, E.7    Terreno, E.8
  • 122
    • 0347480556 scopus 로고    scopus 로고
    • A paramagnetic CEST agent for imaging glucose by MRI
    • Zhang, S.; Trokowski, R.; Sherry, A. D. A paramagnetic CEST agent for imaging glucose by MRI. J. Am. Chem. Soc., 2003, 125 (50), 15288-1529.
    • (2003) J. Am. Chem. Soc. , vol.125 , Issue.50 , pp. 15288-15299
    • Zhang, S.1    Trokowski, R.2    Sherry, A.D.3
  • 123
    • 33750434288 scopus 로고    scopus 로고
    • A PARACEST MRI contrast agent to detect enzyme activity
    • Yoo, B.; Pagel, M. D. A PARACEST MRI contrast agent to detect enzyme activity. J. Am. Chem. Soc., 2006, 128(43), 14032-14033.
    • (2006) J. Am. Chem. Soc. , vol.128 , Issue.43 , pp. 14032-14033
    • Yoo, B.1    Pagel, M.D.2
  • 124
    • 25144512977 scopus 로고    scopus 로고
    • A Gadolinium chelate for detection of OE??-glucuronidase:'Äâ A self-immolative approach
    • Duimstra, J. A.; Femia, F. J.; Meade, T. J. A Gadolinium chelate for detection of OE??-glucuronidase:'Äâ A self-immolative approach. J. Am. Chem. Soc., 2005, 127(37), 12847-12855.
    • (2005) J. Am. Chem. Soc. , vol.127 , Issue.37 , pp. 12847-12855
    • Duimstra, J.A.1    Femia, F.J.2    Meade, T.J.3
  • 125
    • 46749158331 scopus 로고    scopus 로고
    • TÛth, v. Detection of Enzymatic Activity by PARACEST MRI: A General Approach to Target a Large Variety of Enzymes13
    • [Chauvin, T.; Durand, P.; Bernier, M.; Meudal, H.; Doan, B.-T.; Noury, F.; Badet, B.; Beloeil, J.-C.; TÛth, v. Detection of Enzymatic Activity by PARACEST MRI: A General Approach to Target a Large Variety of Enzymes13. Angew. Chemie Intl. Ed., 2008, 47(23), 4370-4372.
    • (2008) Angew. Chemie Intl. Ed. , vol.47 , Issue.23 , pp. 4370-4372
    • Chauvin, T.1    Durand, P.2    Bernier, M.3    Meudal, H.4    Doan, B.-T.5    Noury, F.6    Badet, B.7    Beloeil, J.-C.8
  • 127
    • 2542579552 scopus 로고    scopus 로고
    • Tracking the recruitment of diabetogenic CD8+ T-cells to the pancreas in real time
    • Moore, A.; Grimm, J.; Han, B.; Santamaria, P. Tracking the recruitment of diabetogenic CD8+ T-cells to the pancreas in real time. Diabetes, 2004, 53 (6), 1459-1466.
    • (2004) Diabetes , vol.53 , Issue.6 , pp. 1459-1466
    • Moore, A.1    Grimm, J.2    Han, B.3    Santamaria, P.4
  • 128
    • 65549161510 scopus 로고    scopus 로고
    • Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles
    • Islam, T.; Josephson, L. Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles. Cancer Biomarkers, 2009, 5 (2), 99-107.
    • (2009) Cancer Biomarkers , vol.5 , Issue.2 , pp. 99-107
    • Islam, T.1    Josephson, L.2
  • 129
    • 33645214569 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticle probes for molecular imaging
    • Thorek, D. L.; Chen, A. K.; Czupryna, J.; Tsourkas, A. Superparamagnetic iron oxide nanoparticle probes for molecular imaging. Ann. Biomed. Eng., 2006, 34 (1), 23-38.
    • (2006) Ann. Biomed. Eng. , vol.34 , Issue.1 , pp. 23-38
    • Thorek, D.L.1    Chen, A.K.2    Czupryna, J.3    Tsourkas, A.4
  • 130
    • 0036022520 scopus 로고    scopus 로고
    • Magnetic relaxation switches capable of sensing molecular interactions
    • Perez, J. M.; Josephson, L.; O'Loughlin, T.; Hogemann, D.; Weissleder, R. Magnetic relaxation switches capable of sensing molecular interactions. Nat. Biotech., 2002, 20 (8), 816-820.
    • (2002) Nat. Biotech. , vol.20 , Issue.8 , pp. 816-820
    • Perez, J.M.1    Josephson, L.2    O'Loughlin, T.3    Hogemann, D.4    Weissleder, R.5
  • 131
    • 0037181368 scopus 로고    scopus 로고
    • DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNAcleaving agents
    • Perez, J. M.; O'Loughin, T.; Simeone, F. J.; Weissleder, R.; Josephson, L. DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNAcleaving agents. J. Am. Chem. Soc., 2002, 124 (12), 2856-2857.
    • (2002) J. Am. Chem. Soc. , vol.124 , Issue.12 , pp. 2856-2857
    • Perez, J.M.1    O'Loughin, T.2    Simeone, F.J.3    Weissleder, R.4    Josephson, L.5
  • 134
    • 1642515770 scopus 로고    scopus 로고
    • Novel nanosensors for rapid analysis of telomerase activity
    • Grimm, J.; Perez, J. M.; Josephson, L.; Weissleder, R. Novel nanosensors for rapid analysis of telomerase activity. Cancer Res., 2004, 64(2), 639-643.
    • (2004) Cancer Res , vol.64 , Issue.2 , pp. 639-643
    • Grimm, J.1    Perez, J.M.2    Josephson, L.3    Weissleder, R.4
  • 135
    • 54249139118 scopus 로고    scopus 로고
    • Integrated nanosensors to determine levels and functional activity of human telomerase
    • Perez, J. M.; Grimm, J.; Josephson, L.; Weissleder, R. Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia 2008, 10 (10), 1066-1072.
    • (2008) Neoplasia , vol.10 , Issue.10 , pp. 1066-1072
    • Perez, J.M.1    Grimm, J.2    Josephson, L.3    Weissleder, R.4
  • 140
    • 39449109172 scopus 로고    scopus 로고
    • Single-coil, multisample, proton relaxation method for magnetic relaxation switch assays
    • Lowery, T. J.; Palazzolo, R.; Wong, S. M.; Prado, P. J.; Taktak, S. Single-coil, multisample, proton relaxation method for magnetic relaxation switch assays. Analyt. Chem., 2008, 80 (4), 1118-1123.
    • (2008) Analyt. Chem. , vol.80 , Issue.4 , pp. 1118-1123
    • Lowery, T.J.1    Palazzolo, R.2    Wong, S.M.3    Prado, P.J.4    Taktak, S.5
  • 141
    • 47049094596 scopus 로고    scopus 로고
    • Sensitive NMR sensors detect antibodies to influenza
    • [Koh, I.; Hong, R.; Weissleder, R.; Josephson, L. Sensitive NMR sensors detect antibodies to influenza. Angew. Chemie Intl. Ed., 2008, 47 (22), 4119-4121.
    • (2008) Angew. Chemie Intl. Ed. , vol.47 , Issue.22 , pp. 4119-4121
    • Koh, I.1    Hong, R.2    Weissleder, R.3    Josephson, L.4
  • 142
    • 49149122934 scopus 로고    scopus 로고
    • Chip-NMR biosensor for detection and molecular analysis of cells
    • Lee, H.; Sun, E.; Ham, D.; Weissleder, R. Chip-NMR biosensor for detection and molecular analysis of cells. Nat. Med., 2008, 14(8), 869-874.
    • (2008) Nat. Med. , vol.14 , Issue.8 , pp. 869-874
    • Lee, H.1    Sun, E.2    Ham, D.3    Weissleder, R.4
  • 143
    • 0025246226 scopus 로고
    • NMR detection of creatine kinase expressed in liver of transgenic mice: Determination of free ADP levels
    • Koretsky, A. P.; Brosnan, M. J.; Chen, L. H.; Chen, J. D.; Van Dyke, T. NMR detection of creatine kinase expressed in liver of transgenic mice: determination of free ADP levels. Proc. Natl. Acad. Sci. USA, 1990, 87 (8), 3112-3116.
    • (1990) Proc. Natl. Acad. Sci. USA. , vol.87 , Issue.8 , pp. 3112-3116
    • Koretsky, A.P.1    Brosnan, M.J.2    Chen, L.H.3    Chen, J.D.4    van Dyke, T.5
  • 146
    • 70349976207 scopus 로고    scopus 로고
    • Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI
    • Mizukami, S.; Takikawa, R.; Sugihara, F.; Shirakawa, M.; Kikuchi, K., Dual-function probe to detect protease activity for fluorescence measurement and 19F MRI. Angew. Chem. Int. Ed. Engl., 2009, 48 (20), 3641.
    • (2009) Angew. Chem. Int. Ed. Engl. , vol.48 , Issue.20 , pp. 3641
    • Mizukami, S.1    Takikawa, R.2    Sugihara, F.3    Shirakawa, M.4    Kikuchi, K.5
  • 148
    • 38049103113 scopus 로고    scopus 로고
    • Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR
    • Merritt, M. E.; Harrison, C.; Storey, C.; Jeffrey, F. M.; Sherry, A. D.; Malloy, C. R. Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. Proc. Natl. Acad. Sci. USA, 2007, 104(50), 19773-19777.
    • (2007) Proc. Natl. Acad. Sci. USA. , vol.104 , Issue.50 , pp. 19773-19777
    • Merritt, M.E.1    Harrison, C.2    Storey, C.3    Jeffrey, F.M.4    Sherry, A.D.5    Malloy, C.R.6
  • 152
    • 4244082343 scopus 로고    scopus 로고
    • Shedding light on cell signaling: Interpretation of FRET biosensors
    • [Gaits, F.; Hahn, K. Shedding light on cell signaling: interpretation of FRET biosensors. Sci. STKE, 2003, 2003(165), pe 3
    • (2003) Sci. STKE. , vol.2003 , Issue.165 , pp. 3
    • Gaits, F.1    Hahn, K.2
  • 155
    • 0037995710 scopus 로고    scopus 로고
    • Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis
    • Hu, C.-D.; Kerppola, T. K., Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis. Nat. Biotech., 2003, 21 (5), 539-545.
    • (2003) Nat. Biotech. , vol.21 , Issue.5 , pp. 539-545
    • Hu, C.-D.1    Kerppola, T.K.2
  • 156
    • 36248973801 scopus 로고    scopus 로고
    • Quantum dot aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer
    • Bagalkot, V.; Zhang, L.; Levy-Nissenbaum, E.; Jon, S.; Kantoff, P. W.; Langer, R.; Farokhzad, O. C. Quantum dot aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett., 2007, 7 (10), 3065-3070.
    • (2007) Nano Lett , vol.7 , Issue.10 , pp. 3065-3070
    • Bagalkot, V.1    Zhang, L.2    Levy-Nissenbaum, E.3    Jon, S.4    Kantoff, P.W.5    Langer, R.6    Farokhzad, O.C.7
  • 157
    • 68149166462 scopus 로고    scopus 로고
    • Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity
    • [Blum, G.; Weimer, R. M.; Edgington, L. E.; Adams, W.; Bogyo, M. Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity. PLoS One, 2009, 4(7), e6374.
    • (2009) PLoS One , vol.4 , Issue.7
    • Blum, G.1    Weimer, R.M.2    Edgington, L.E.3    Adams, W.4    Bogyo, M.5
  • 159
    • 2542601328 scopus 로고    scopus 로고
    • Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target
    • Potter, C.; Harris, A. L. Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target. Cell Cycle, 2004, 3 (2), 164-167.
    • (2004) Cell Cycle , vol.3 , Issue.2 , pp. 164-167
    • Potter, C.1    Harris, A.L.2
  • 160
    • 77956283843 scopus 로고    scopus 로고
    • Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts
    • [Carlin, S.; Khan, N.; Ku, T.; Longo, V. A.; Larson, S. M.; Smith-Jones, P. M. Molecular targeting of carbonic anhydrase IX in mice with hypoxic HT29 colorectal tumor xenografts. PLoS One, 2010, 5 (5), e10857.
    • (2010) PLoS One , vol.5 , Issue.5
    • Carlin, S.1    Khan, N.2    Ku, T.3    Longo, V.A.4    Larson, S.M.5    Smith-Jones, P.M.6
  • 161
    • 79959864803 scopus 로고    scopus 로고
    • Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and 124I-cG250 PET/CT. Urologic oncology
    • Lawrentschuk, N.; Lee, F. T.; Jones, G.; Rigopoulos, A.; Mountain, A.; O'Keefe, G.; Papenfuss, A. T.; Bolton, D. M.; Davis, I. D.; Scott, A. M. Investigation of hypoxia and carbonic anhydrase IX expression in a renal cell carcinoma xenograft model with oxygen tension measurements and 124I-cG250 PET/CT. Urologic oncology: Semin. Original Investig., 2007, 29(4),411-420.
    • (2007) Semin. Original Investig. , vol.29 , Issue.4 , pp. 411-420
    • Lawrentschuk, N.1    Lee, F.T.2    Jones, G.3    Rigopoulos, A.4    Mountain, A.5    O'Keefe, G.6    Papenfuss, A.T.7    Bolton, D.M.8    Davis, I.D.9    Scott, A.M.10
  • 162
    • 33947504376 scopus 로고    scopus 로고
    • Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: A phase I trial
    • Divgi, C. R.; Pandit-Taskar, N.; Jungbluth, A. A.; Reuter, V. E.; Gnen, M.; Ruan, S.; Pierre, C.; Nagel, A.; Pryma, D. A.; Humm, J.; Larson, S. M.; Old, L. J.; Russo, P. Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: a phase I trial. Lancet Oncol., 2007, 8(4), 304-310.
    • (2007) Lancet Oncol , vol.8 , Issue.4 , pp. 304-310
    • Divgi, C.R.1    Pandit-Taskar, N.2    Jungbluth, A.A.3    Reuter, V.E.4    Gnen, M.5    Ruan, S.6    Pierre, C.7    Nagel, A.8    Pryma, D.A.9    Humm, J.10    Larson, S.M.11    Old, L.J.12    Russo, P.13
  • 163
    • 33750989362 scopus 로고    scopus 로고
    • 2-Aminothiazole as a novel kinase inhibitor template. Structure'àíactivity relationship studies toward the discovery of N- (2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5- carboxamide (Dasatinib, BMS-354825) as a potent pan-src kinase inhibitor
    • Das, J.; Chen, P.; Norris, D.; Padmanabha, R.; Lin, J.; Moquin, R. V.; Shen, Z.; Cook, L. S.; Doweyko, A. M.; Pitt, S.; Pang, S.; Shen, D. R.; Fang, Q.; de Fex, H. F.; McIntyre, K. W.; Shuster, D. J.; Gillooly, K. M.; Behnia, K.; Schieven, G. L.; Wityak, J.; Barrish, J. C., 2-Aminothiazole as a novel kinase inhibitor template. Structure'àíactivity relationship studies toward the discovery of N- (2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5- carboxamide (Dasatinib, BMS-354825) as a potent pan-src kinase inhibitor. J. Med. Chem., 2006, 49 (23), 6819-6832.
    • (2006) J. Med. Chem. , vol.49 , Issue.23 , pp. 6819-6832
    • Das, J.1    Chen, P.2    Norris, D.3    Padmanabha, R.4    Lin, J.5    Moquin, R.V.6    Shen, Z.7    Cook, L.S.8    Doweyko, A.M.9    Pitt, S.10    Pang, S.11    Shen, D.R.12    Fang, Q.13    de Fex, H.F.14    McIntyre, K.W.15    Shuster, D.J.16    Gillooly, K.M.17    Behnia, K.18    Schieven, G.L.19    Wityak, J.20    more..
  • 165
    • 84857751739 scopus 로고    scopus 로고
    • Localization of human prostate cancer through PET imaging using a novel dasatinib analog in mice
    • MeetingAbstracts_1
    • Santos, E.; Veach, D.; Pillarsetty, N.; Punzalan, B.; Larson, S. Localization of human prostate cancer through PET imaging using a novel dasatinib analog in mice. J. Nucl. Med. Meeting Abs., 2008, 49 (MeetingAbstracts_1), 106P-b
    • (2008) J. Nucl. Med. Meeting Abs. , vol.49
    • Santos, E.1    Veach, D.2    Pillarsetty, N.3    Punzalan, B.4    Larson, S.5
  • 167
    • 2442652873 scopus 로고    scopus 로고
    • Catheter-based in vivo imaging of enzyme activity and gene expression: Feasibility study in mice1
    • Funovics, M. A.; Weissleder, R.; Mahmood, U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice1. Radiology, 2004, 231(3), 659-666.
    • (2004) Radiology , vol.231 , Issue.3 , pp. 659-666
    • Funovics, M.A.1    Weissleder, R.2    Mahmood, U.3
  • 168
    • 77951619720 scopus 로고    scopus 로고
    • FDA report: Ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease
    • Lu, M.; Cohen, M. H.; Rieves, D.; Pazdur, R. FDA report: Ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease. Am. J. Hematol., 2010, 85(5), 315-319.
    • (2010) Am. J. Hematol. , vol.85 , Issue.5 , pp. 315-319
    • Lu, M.1    Cohen, M.H.2    Rieves, D.3    Pazdur, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.