Evaluation of chemical, physical, and biologic properties of tumor-targeting radioiodinated quinazolinone derivative

Bioconjugate Chemistry

Volumn 18, Issue 3, 2007, Pages 754-764

  Wang, Ketai ^a   Kirichian, Agop M ^a   Al Aowad, Ayman F ^a   Adelstein, S James ^a   Kassis, Amin I ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINITY; CELL CULTURE; CELLS; DISEASES; DRUG DELIVERY; HYDROLYSIS; ISOMERS; MAMMALS; MEDICAL IMAGING; SOLUTIONS; TUMORS;

4(3H)-QUINAZOLINONES; ALKALINE PHOSPHATASE; IN-VIVO; PRODRUGS; PROPERTY; RADIOIODINATION; SOLID TUMORS; TUMOR CELL LINES; TUMOR-TARGETING; TUMOUR CELLS;

PHOSPHATASES;

2 (2' HYDROXYPHENYL) 6 IODO 4(3H) QUINAZOLINONE I 125; 2 (2' PHOSPHORYLOXYPHENYL) 6 IODO 4(3H) QUINAZOLINONE I 125; ALKALINE PHOSPHATASE; AMMONIUM 2 (2' PHOSPHORYLOXYPHENYL) 6 TRIBUTYLSTANNYL 4(3H) QUINAZOLINONE; DIMETHYL SULFOXIDE; PRODRUG; QUINAZOLINONE DERIVATIVE; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEPHOSPHORYLATION; DRUG HYDROLYSIS; ENZYME ACTIVITY; ENZYME MEDIATED CANCER IMAGING AND THERAPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYDROLYSIS; IN VIVO STUDY; ISOMER; ISOTOPE LABELING; KIDNEY; LIVER; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRECIPITATION; RADIOIODINATION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID TUMOR; SOLUBILITY; TECHNOLOGY; TISSUE DISTRIBUTION; TUMOR CELL; TUMOR CELL LINE;

EID: 33947264285     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc0602937     Document Type: Article

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