Synthesis and biologic evaluation of a radioiodinated quinazolinone derivative for enzyme-mediated insolubilization therapy

Bioconjugate Chemistry

Volumn 13, Issue 2, 2002, Pages 357-364

  Ho, Nan Hui ^a   Harapanhalli, Ravi S ^a   Dahman, Bassam A ^a   Chen, Kai ^a   Wang, Ketai ^a   Adelstein, S James ^a   Kassis, Amin I ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTOLOGY; MAMMALS; RADIOISOTOPES; TUMORS;

4(3H)-QUINAZOLINONES; ALKALINE PHOSPHATASE; ENZYME-MEDIATED; IN-VIVO; IODINE-125; PRODRUGS; QUINAZOLINONES; SITE-SPECIFIC; SOLID TUMORS; THERAPEUTIC RADIONUCLIDES;

PHOSPHATASES;

ALKALINE PHOSPHATASE; AMMONIUM 2 (2' PHOSPHORYLOXYPHENYL) 6 IODO 4 (3H) QUINAZOLINONE; AMMONIUM 2-(2'-PHOSPHORYLOXYPHENYL)-6-IODO-4-(3H)-QUINAZOLINONE; PRODRUG; QUATERNARY AMMONIUM DERIVATIVE; QUINAZOLINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; RADIOACTIVE IODINE;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; CHEMISTRY; DRUG DELIVERY SYSTEM; FLUORESCENCE; METABOLISM; METHODOLOGY; MOUSE; SENSITIVITY AND SPECIFICITY; SOLUBILITY; SYNTHESIS;

ALKALINE PHOSPHATASE; ANIMALS; DRUG DELIVERY SYSTEMS; FLUORESCENCE; IODINE RADIOISOTOPES; MICE; ORGAN SPECIFICITY; PRODRUGS; QUATERNARY AMMONIUM COMPOUNDS; QUINAZOLINES; QUINAZOLINONES; SENSITIVITY AND SPECIFICITY; SOLUBILITY;

EID: 0036009653     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc010093p     Document Type: Article

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