TLR signaling paralyzes monocyte chemotaxis through synergized effects of p38 MAPK and global rap-1 activation

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Yi, Ling ^a   Chandrasekaran, Prabha ^a   Venkatesan, Sundararajan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR2; G PROTEIN COUPLED RECEPTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; RAP1 PROTEIN; TOLL LIKE RECEPTOR; CHEMOKINE; FORMYLPEPTIDE RECEPTOR;

ARTICLE; CALCIUM TRANSPORT; CELL CYCLE ARREST; CELL DIFFERENTIATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOCYTOSIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DYNAMICS; MONOCYTE; POLARIZATION; POLYMORPHONUCLEAR CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL LINE; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; PHYSIOLOGY;

CELL LINE; CHEMOKINES; CHEMOTAXIS, LEUKOCYTE; DRUG SYNERGISM; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RAP1 GTP-BINDING PROTEINS; RECEPTORS, FORMYL PEPTIDE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84856809736     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030404     Document Type: Article

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