Cholesterol is obligatory for polarization and chemotaxis but not for endocytosis and associated signaling from chemoattractant receptors in human neutrophils

Journal of Biomedical Science

Volumn 15, Issue 4, 2008, Pages 441-461

  Rose, Jeremy J ^a   Foley, John F ^a   Yi, Ling ^a   Herren, Gina ^a   Venkatesan, Sundararajan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Arrestin; Chemoattractants; Chemotaxis; Cholesterol; Degranulation; Endocytosis; F actin; G proteins; Lipid rafts; Neutrophils; Protein kinases

Indexed keywords

BETA ARRESTIN; CHEMOATTRACTANT; CHOLESTEROL; CXCL1 CHEMOKINE; CYTOSKELETON PROTEIN; F ACTIN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HEMATOPOIETIC CELL KINASE; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN TYROSINE KINASE; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; CALCIUM TRANSPORT; CELL STIMULATION; CHEMOTAXIS; CONTROLLED STUDY; DEGRANULATION; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME INHIBITION; EXOCYTOSIS; HUMAN; HUMAN CELL; LIPID RAFT; NEUTROPHIL; NEUTROPHIL GRANULE; POLARIZATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION;

ACTINS; CELL POLARITY; CHEMOTAXIS; CHOLESTEROL; ENDOCYTOSIS; HUMANS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; NEUTROPHILS; RECEPTORS, FORMYL PEPTIDE; SIGNAL TRANSDUCTION;

EID: 44949214002     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-008-9239-x     Document Type: Article

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