Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytes

Journal of Immunology

Volumn 156, Issue 3, 1996, Pages 1157-1165

  Herrera Velit, Patricia ^a   Reiner, Neil E ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; HERBIMYCIN A; PHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHORUS 32; POLYPHOSPHOINOSITIDE; PROTEIN TYROSINE KINASE; WORTMANNIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CONTROLLED STUDY; DEACYLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTIGENS, CD14; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME ACTIVATION; HUMANS; KINETICS; LIPOPOLYSACCHARIDES; LYMPHOMA, LARGE-CELL; MACROPHAGE ACTIVATION; MONOCYTES; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SRC-FAMILY KINASES; TUMOR CELLS, CULTURED;

EID: 0030070975     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Ulevitch, R J. 1993. Recognition of bacterial endotoxins by receptor-dependent mechanisms. Adv. Immunol 53.267.
2. Gegner, J A , R. J. Ulevitch, and P. S Tobias. 1995. Lipopolysaccharide (LPS) signal transduction and clearance: dual roles for LPS binding protein and membrane CD14. J. Biol. Chem. 270.5320.
3. Weinstein, S. L., M. R. Gold, and A L DeFranco. 1991. Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages. Proc. Natl. Acad Sci USA 88:4148.
4. Weinstein, S. L , C. H. June, and A. L. DeFranco. 1993 Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14. J. Immunol 151:3829.
5. English, B. K., J. N. Ihle, A. Myracle, and T. Yi 1993 Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages. J. Exp. Med 178:1017.
6. lyn. J Biol. Chem. 268:20725
7. Beaty, C D., T. L. Franklin, Y. Uehara, and C. B. Wilson. 1994 Lipopolysaccharide-induced cytokine production in human monocytes: role of tyrosine phosphorylation in transmembrane signal transduction Eur. J. Immunol. 24:1278.
8. Weinstein, S L , J. S. Sanghera, K. Lemke, A. L. DeFranco, and S. L Pelech. 1992. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J Biol. Chem 267:14955
9. Dong, Z , X Qi, and I. J Fidler 1993. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J. Exp Med. 177:1071.
10. Liu, M. K., P Herrera-Velit, R. W. Brownsey, and N. E. Reiner. 1994. CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide. J. Immunol 153:2642.
11. Shapira, L , S Takashiba, C. Champagne, S Amar, and T. E. Van Dyke. 1994 Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes. J Immunol. 153:1818
12. Gold, M. R . V. Duronio, S P. Saxena, J W. Schrader, and R. Aebersold 1994. Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells: association of the enzyme with various tyrosine-phosphorylated proteins. J. Biol. Chem 269:5403
13. Stephens, L R , K. T. Hughes, and R F Irvine 1991. Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils Nature 351:33.
14. Gold, M. R , and R. Aebersold. 1994. Both phosphatidylinositol 3-kinase and phosphatidylinositol 4-kinase products are increased by antigen receptor signaling in B cells. J. Immunol. 152:42.
15. Cantley, L. C., K. R. Auger, C. Carpenter, B. Duckworth, A. Graziam, R. Kapeller, and S Soltoff. 1991. Oncogenes and signal transduction Cell 64:281.
16. Nakanishi, H., K. A. Brewer, and J. H. Exton 1993. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268:13.
17. 3. J. Biol Chem. 269 32358.
18. Olivier, M., K. G. Baimbridge, and N. E Reiner. 1992. Stimulus-response coupling in monocytes infected with Leishmania: attenuation of calcium transients is related to defective agonist-induced accumulation of inositol phosphates. J. Immunol 148:1188.
19. Arcaro, A., and M P. Wymann 1994. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses Biochem. J. 296.297.
20. Wright, S D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431.
21. Fry, M. J. 1994. Structure, regulation and function of phosphoinositide 3-kinases. Biochim. Biophys. Acta 1226:237.
22. Yamanashi, Y., Y. Fukui, B. Wongsasant, Y. Kinoshita, Y. Ichimori, K. Toyoshima, and T. Yamamoto, 1992. Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling Proc. Natl. Acad. Sci USA 89:1118.
23. Han, J., J.-D. Lee, P. S. Tobias, and R. J. Ulevitch. 1993. Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J. Biol. Chem. 268:25009.
24. Whitman, M., D R. Kaplan, B Schaffhausen, L Cantley, and T. M. Roberts 1985. Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation. Nature 315 239.
25. lck regulates the activity of phosphatidylinositol-3′-kinase in interleukin-2-dependent T-cells. J. Biol. Chem. 268(Suppl. 27):20031.
26. Pleiman, C. M., W. M. Hertz, and J. C Cambier. 1994. Activation of phosphatidylinositol-3′ kinase by src family kinase SH3 binding to the p85 subunit. Science 263.1609.
27. Ren, C. L., T Morio, S. M. Fu, and R. S. Geha. 1994. Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase Cγ2. J. Exp. Med 179:673.
28. Okada, T., L. Sakuma, Y. Fukui, O. Hazeki, and M Ui 1994. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J Biol Chem. 269.3563.
29. Van Voorhis, W. C., R. M. Steinman, L. S Hair, J Luban, M D. Witmer, S. Koide, and Z. A. Conn. 1983 Specific anti-mononuclear phagocyte monoclonal antibodies. J. Exp Med 158:126.
30. Herbst, J. J , G. Andrews, L. Contillo, L. Lamphere, J. Gardner, G. E Lienhard, and E. M. Gibbs. 1994 Potent activation of phosphatidylinositol 3′-kinase by simple phosphotyrosine peptides derived from insulin receptor substrate 1 containing two YMXM motifs for binding SH2 domains. Biochemistry 33:9376.
31. Carpenter, C. L , K R. Auger, M. Chanudhuri, M Yoakim, B Schaffhausen, S. Shoelson, and L. C. Cantley. 1993 Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit. J. Biol. Chem 268:9478.
32. Van der Geer, P , T. Hunter, and R. A Lindberg. 1994. Receptor protein-tyrosine kinases and their signal transduction pathways. Annu. Rev. Cell Biol. 10:251.
33. Kodaki, T., R. Woscholski, B. Hallberg, P. Rodriguez-Viciana, J. Downward, and P J Parker. 1994. The activation of phosphatidylinositol 3-kinase by Ras Curr. Biol. 4:798.
34. Büscher, D., R. A. Hipskind, S. Krautwald, T. Reimann, and M. Baccanni 1995. Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages Mol Cell. Biol 15:466.
35. Jakway, J. P., and A. L. DeFranco. 1986. Pertussis toxin inhibition of B cell and macrophage responses to bactenal lipopolysaccharide. Science 234:743.
36. Daniel-Issakani, S., A. M Spiegel, and B. Strulovici. 1989 Lipopolysaceharide response is linked to the GTP binding protein, Gi2, in the promonocytic cell line U937. J. Biol. Chem. 264(Suppl 34) 20240.
37. Thomason, P. A., S. R. James, P J. Casey, and C. P. Downes. 1994. A G-protein βγ-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol. J. Biol Chem. 269.16525
38. Stephens, L , A. Smrcka, F T. Cooke, T. R Jackson, P. C Sternweis, and P. T. Hawkins 1994 A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits. Cell 77:83.
39. Stoyanov, B., S Volinia, T Hanck, I. Rubio, M. Loubtchenkov, D Malek, S. Stovanova, B. Vanhaesebroeck, R. Dhand, B. Nurnberg, P. Gierschik, K Seedorf, J. J Hsuan, M. D. Waterfield, and R. Wetzker. 1995. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 269.690.
40. Ptasznik, A., A. Traynor-Kaplan, and G. M. Bokoch. 1995. G protein-coupled chemoattractant receptors regulate lyn tyrosine kinase Shc adapter protein signaling complexes. J. Biol. Chem 270 19969.
41. Monfar, M., K P. Lemon, T. C. Crammer, L. Cheatham, J. Chung, C. J Vlahos, and J. Blenis. 1995. Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP Mol Cell Biol. 15:326