A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK

Nature Cell Biology

Volumn 4, Issue 11, 2002, Pages 901-906

  Enserink, Jorrit M ^a   Christensen, Anne E ^b   De Rooij, Johan ^a,c   Van Triest, Miranda ^a   Schwede, Frank ^d   Genieser, Hans Gottfried ^d   Døskeland, Stein O ^b   Blank, Jonathan L ^b,e   Bos, Johannes L ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF BERGEN   (Norway)

^c Semaia Pharmaceuticals BV   (Netherlands)

^d BIOLOG Life Science Institute   (Germany)

^e UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DERIVATIVE; GROWTH FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG DESIGN; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RAP1 GTP-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 85006314494     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb874     Document Type: Article

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