LPS differentially regulates adhesion and transendothelial migration of human monocytes under static and flow conditions

International Immunology

Volumn 20, Issue 2, 2008, Pages 247-257

  Bradfield, Paul F ^a   Johnson Léger, Caroline A ^a,b   Zimmerli, Claudia ^a   Imhof, Beat A ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b MERCK SERONO S A   (Switzerland)

Author keywords

Flow; Leukocytes; LPS; Monocytes; Transendothelial migration

Indexed keywords

BETA1 INTEGRIN; BETA2 INTEGRIN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR;

ANTIGEN RECOGNITION; ARTICLE; BLOOD FLOW; BLOOD VESSEL PERMEABILITY; BLOOD VESSEL WALL; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; DISEASE SEVERITY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; MONOCYTE; MONOLAYER CULTURE; NEUTROPHIL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SEPSIS; SEPTIC SHOCK; UMBILICAL VEIN; VASODILATATION;

ANTIGENS, CD18; CELL ADHESION; CELL MIGRATION INHIBITION; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIUM, VASCULAR; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; UMBILICAL VEINS;

EID: 39049119917     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxm136     Document Type: Article

References (58)

1. Imhof, B. A. and Dunon, D. 1995. Leukocyte migration and adhesion. Adv. Immunol. 58:345.
2. Butcher, E. C. and Picker, L. J. 1996. Lymphocyte homing and homeostasis. Science 272:60.
3. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 76:301.
4. Johnson-Leger, C., Aurrand-Lions, M. and Imhof, B. A. 2000. The parting of the endothelium: Miracle, or simply a junctional affair? J. Cell Sci. 113:(Pt 6)921.
5. Janeway, C. A.J. and Travers, P. 1996. Immuno-biology: The Immune System in Health and Disease. Garland Publishing Inc, London.
6. Ulevitch, R. J. and Tobias, P. S. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437.
7. Rietschel, E. T., Brade, H., Holst, O. et al. 1996. Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification. Curr. Top. Microbiol. Immunol. 216:39.
8. Akira, S., Takeda, K. and Kaisho, T. 2001. Toll-like receptors: Critical proteins linking innate and acquired immunity. Nat. Immunol. 2 675.
9. Parrillo, J. E. 1993. Pathogenetic mechanisms of septic shock. N. Engl. J. Med. 328:1471.
10. David, S. A. 2001. Towards a rational development of anti-endotoxin agents: Novel approaches to sequestration of bacterial endotoxins with small molecules. J. Mol. Recognit. 14:370.
11. Bauss, F., Droge, W. and Mannel, D. N. 1987. Tumor necrosis factor mediates endotoxic effects in mice. Infect. Immun. 55:1622.
12. van der, P. T., Buller, H. R., ten Cate, H. et al. 1990. Activation of coagulation after administration of tumor necrosis factor to normal subjects. N. Engl. J. Med. 322:1622.
13. Noto, K., Kato, K., Okumura, K. and Yagita, H. 1995. Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7:835.
14. Wall, R. T., Harker, L. A., Quadracci, L. J. and Striker, G. E. 1978. Factors influencing endothelial cell proliferation in vitro. J. Cell Physiol. 96:203.
15. Hashimoto, S., Nagai, S., Sese, J. et al. 2003. Gene expression profile in human leukocytes. Blood 101:3509.
16. Bradfield, P. F., Amft, N., Vernon-Wilson, E. et al. 2003. Rheumatoid fibroblast-like synoviocytes overexpress the chemokine stromal cell-derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue. Arthritis Rheum. 48:2472.
17. Cooke, B. M., Usami, S., Perry, I. and Nash, G. B. 1993. A simplified method for culture of endothelial cells and analysis of adhesion of blood cells under conditions of flow. Microvasc. Res. 45:33.
18. Luu, N. T, Rainger, G. E. and Nash, G. B. 1999. Kinetics of the different steps during neutrophil migration through cultured endothelial monolayers treated with tumour necrosis factor-alpha. J. Vasc. Res. 36:477.
19. Bradfield, P. F., Scheiermann, C., Nourshargh, S. et al. 2007. JAM-C regulates unidirectional monocyte transendothelial migration in inflammation. Blood 110:2545.
20. Buckley, C. D., Amft, N., Bradfield, P. F. et al. 2000. Persistent induction of the chemokine receptor CXCR4 by TGF-beta 1 on synovial T. cells contributes to their accumulation within the rheumatoid synovium. J. Immunol. 165:3423.
21. van Buul, J. D. and Hordijk, P. L. 2004. Signaling in leukocyte transendothelial migration. Arterioscler. Thromb. Vasc. Biol. 24:824.
22. Kim, H. K., Kim, J. E. Chung, J., Han, K. S. and Cho, H. I. 2007. Surface expression of neutrophil CXCR4 is down-modulated by bacterial endotoxin. Int. J. Hematol. 85:390.
23. Duff, G. W. and Atkins, E. 1982. The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production. J. Immunol. Methods 52:333.
24. Morrison, D. C. and Jacobs, D. M. 1976. Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. Immunochemistry 13:813.
25. Brandtzaeg, P. 1996. Significance and pathogenesis of septic shock. Curr. Top. Microbiol. Immunol. 216:15.
26. Moller, A. S., Bjerre, A., Brusletto, B., Joo, G. B., Brandtzaeg, P. and, Kierulf, R 2005. Chemokine patterns in meningococcal disease. J. Infect Dis. 191:768.
27. Doherty, D. E., Zagarella, L., Henson, P. M. and Worthen, G. S. 1989. Lipopolysaccharide stimulates monocyte adherence by effects on both the monocyte and the endothelial cell. J. Immunol. 143:3673.
28. Williams, L. M. and Ridley, A. J. 2000. Lipopolysaccharide induces actin reorganization and tyrosine phosphorylation of Pyk2 and paxillin in monocytes and macrophages. J. Immunol. 164:2028.
29. Faure, E., Equils, O., Sieling, P. A. et al. 2000. Bacterial lipopolysaccharide activates NF-kappaB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells. Differential expression of TLR-4 and TLR-2 in endothelial cells. J. Biol. Chem. 275:11058.
30. Faure, E., Thomas, L., Xu, H., Medvedev, A., Equils, O. and Arditi, M. 2001. Bacterial lipopolysaccharide and IFN-gamma induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: Role of NF-kappa B activation. J. Immunol. 166:2018.
31. Zeuke, S., Ulmer, A. J., Kusumoto, S., Katus, H. A. and Heine, H. 2002. TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc. Res. 56:126.
32. Edelman, D. A., Jiang, Y, Tyburski, J. G., Wilson, R. F. and Steffes, C. P. 2007. Lipopolysaccharide activation of pericyte's Toll-like receptor-4 regulates co-culture permeability. Am. J. Surg. 193:730.
33. Nakamura, N., Yoshida, M., Umeda, M. et al. 2007. Extended exposure of lipopolysaccharide fraction from Porphyromonas gingivalis facilitates mononuclear cell adhesion to vascular endothelium via Toll-like receptor-2 dependent mechanism. Atherosclerosis. Epup ahead of print.
34. Stewart, M., Thiel, M. and Hogg, N. 1995. Leukocyte integrins. Curr. Opin. Cell Biol. 7:690.
35. Owen, C. A., Campbell, E. J. and Stockley, R. A. 1992. Monocyte adherence to fibronectin: Role of CD11/CD18 integrins and relationship to other monocyte functions. J. Leukoc. Biol. 51:400.
36. Hmama, Z., Knutson, K. L., Herrera-Velit, P., Nandan, D. and Reiner, N. E. 1999. Monocyte adherence induced by lipopolysaccharide involves CD14, LFA-1, and cytohesin-1. Regulation by Rho and phosphatidylinositol 3-kinase. J. Biol. Chem. 274:1050.
37. Wang, J. H., Manning, B. J., Wu, Q. D., Blankson, S., Bouchier-Hayes, D. and Redmond, H. P. 2003. Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism. J. Immunol. 170:795.
38. Caron, E., Self, A. J. and Hall, A. 2000. The GTPase Rap 1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators. Curr. Biol. 10:974.
39. Picker, L. J., Treer, J. R., Nguyen, M., Terstappen, L. W., Hogg, N. and Yednock, T. 1993. Coordinate expression of beta 1 and beta 2 integrin "activation" epitopes during T cell responses in secondary lymphoid tissue. Eur J. Immunol. 23:2751.
40. Dougherty, G. J., Dransfield, I. and Hogg, N. 1988. Identification of a novel monocyte cell surface molecule involved in the generation of antigen-induced proliferative responses. Eur. J. Immunol. 18: 2067.
41. Cinamca, G., Shinder, V. and Alon, R. 2001. Shear forces promote lymphocyte migration across vascular endothelium bearing-apical chemokines. Nat Immunol. 2:515.
42. Berlin, C., Bargatze, R. F,, Campbell, J. J. et al. 1995. Alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell 80:413.
43. Alon, R., Kassner, P. D., Carr, M. W., Finger E. B., Hemler, M. E. and Springer, T. A. 1995. The integrin VLA-4 supports tethering and rolling in flow on VCAM-1. J. Cell Biol. 128:1248.
44. Eniola, A. O., Krasik, E. F., Smith, L. A., Song, G. and Hammer, D. A. 2005. I-domain of lymphocyte function-associated antigen-1 mediates rolling of polystyrene particles on ICAM-1 under flow. Biophys. J. 89:3577.
45. Hentzen, E. R., Neelamegham, S., Kansas, G. S. et al. 2000. Sequential binding of CD11a/CD18 and CD11b/CD18 defines neutrophil capture and stable adhesion to intercellular adhesion molecule-1. Blood 95:911.
46. Issekutz, T. B. 1992. Lymphocyte homing to sites of inflammation. Curr. Opin. Immunol. 4:287.
47. Forehand, J. R., Johnston, R. B. Jr and Bomalaski, J: S. 1993. Phospholipase A2 activity in human neutrophils. Stimulation by lipopolysaccharide and possible involvement in priming for an enhadced respiratory burst. J. Immunol. 151:4918.
48. Rose, D. M., Alon, R. and Ginsberg, M. H. 2007. Integrin modulation and signaling in leukocyte adhesion and migration. Immunol. Rev. 218:126.
49. Beutler, B. 2002. TLR4 as the mammalian endotoxin sensor. Curr. Top. Microbiol. Immunol. 270:109.
50. Beutler, B., Hoebe, K., Du, X. and Ulevitch;. R. J. 2003. How we detect microbes and respond to them: The Toll-like receptors and their transducers. J. Leukoc. Biol. 74.479.
51. Cinamon, G., Shinder, V., Shamri, R. and Alon, R. 2004. Chemoattractant signals and beta 2 integrin occupancy at apical endothelial contacts combine with shear stress signals to promote transendothelial neutrophil migration. J. Immunol. 173:7282.
52. Galdlero, M., Folgore, A., Molitierno, M. and Greco, R. 1999. Porins and lipopolysaccharide (LPS) from Salmonella typhimurium induce leucocyte transmigration through human endothelial cells in vitro. Clin. Exp. Immunol. 116:453.
53. Shen, Y., Sultana, C., Arditi, M., Kim, K.S. and Kalra, V. K. 1998. Endotoxin-induced migration of monocytes and PECAM-1 phosphorylation are abrogated by PAF receptor antagonists. Am. J. Physiol. 275:E479.
54. von Andrian, U. H. and Mackay, C. R. 2000. T-cell function and migration. Two sides of the same coin. N. Engl. J. Med. 343:1020.
55. Clark, S. R., Ma, A. C., Tavener, S. A. et al. 2007. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat Med. 13:463.
56. Hurley, J. C. 1995. Endotoxemia: Methods of detection and clinical correlates. Clin. Microbiol. Rev. 8:268.
57. Ge, Y., Ezzell, R. M., Tompkins, R. G. and Warren, H. S. 1994. Cellular distributon of endotoxin after injection of chemically purified lipopolysaccharide differs from that after injection of live bacteria. J. Infect Dis. 169:95.
58. McAllister, S. K., Bland, L. A., Arduino, M. J., Aguero, S. M., Wenger, P. N. and Jarvis, W. R. 1994. Patient cytokineses response in transfusion-associated sepsis. Infect. Immun. 62:212.