An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

Journal of Cell Biology

Volumn 159, Issue 1, 2002, Pages 91-102

  Heit, Bryan ^a   Tavener, Samantha ^a   Raharjo, Eko ^a   Kubes, Paul ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Chemotaxis; Neutrophils; P13K gamma; P38 MAPK; Signal transduction

Indexed keywords

AGAROSE; CHEMOATTRACTANT; CHEMOTACTIC FACTOR; LIPOPOLYSACCHARIDE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SYNAPTOPHYSIN;

ARTICLE; CELL MIGRATION; DECISION MAKING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MODEL; MOLECULE; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CALCIUM; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; INTERLEUKIN-8; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGE-1 ANTIGEN; MITOGEN-ACTIVATED PROTEIN KINASES; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS);

EID: 0037078334     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200202114     Document Type: Article

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