-
1
-
-
78449264186
-
Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication
-
Adeyemi RO, Landry S, Davis ME, Weitzman MD, Pintel DJ. 2010. Parvovirus minute virus of mice induces a DNA damage response that facilitates viral replication. PLoS Pathog. 6:e1001141.
-
(2010)
PLoS Pathog
, vol.6
-
-
Adeyemi, R.O.1
Landry, S.2
Davis, M.E.3
Weitzman, M.D.4
Pintel, D.J.5
-
2
-
-
0034326802
-
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
-
Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE. 2000. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res. 60:5934 -5936.
-
(2000)
Cancer Res
, vol.60
, pp. 5934-5936
-
-
Ahn, J.Y.1
Schwarz, J.K.2
Piwnica-Worms, H.3
Canman, C.E.4
-
3
-
-
63449112088
-
Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events
-
Alazard-Dany N, et al. 2009. Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events. PLoS Pathog. 5:e1000340.
-
(2009)
PLoS Pathog
, vol.5
-
-
Alazard-Dany, N.1
-
4
-
-
37249080597
-
Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair
-
Anantha RW, Vassin VM, Borowiec JA. 2007. Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair. J. Biol. Chem. 282:35910-35923.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 35910-35923
-
-
Anantha, R.W.1
Vassin, V.M.2
Borowiec, J.A.3
-
5
-
-
0025958280
-
Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells
-
Antoni BA, et al. 1991. Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells. J. Virol. 65:396-404.
-
(1991)
J. Virol.
, vol.65
, pp. 396-404
-
-
Antoni, B.A.1
-
6
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist CJ, Kastan MB. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499 -506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
7
-
-
18244385718
-
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
-
Ball HL, Myers JS, Cortez D. 2005. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation. Mol. Biol. Cell 16:2372-2381.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2372-2381
-
-
Ball, H.L.1
Myers, J.S.2
Cortez, D.3
-
8
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin S, et al. 1998. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281:1674 -1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
-
9
-
-
26444444706
-
How adeno-associated virus Rep78 protein arrests cells completely in S phase
-
Berthet C, Raj K, Saudan P, Beard P. 2005. How adeno-associated virus Rep78 protein arrests cells completely in S phase. Proc. Natl. Acad. Sci. U. S. A. 102:13634 -13639.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 13634-13639
-
-
Berthet, C.1
Raj, K.2
Saudan, P.3
Beard, P.4
-
10
-
-
3442896884
-
Replication protein A phosphorylation and the cellular response to DNA damage
-
Binz SK, Sheehan AM, Wold MS. 2004. Replication protein A phosphorylation and the cellular response to DNA damage. DNA Repair 3:1015-1024.
-
(2004)
DNA Repair
, vol.3
, pp. 1015-1024
-
-
Binz, S.K.1
Sheehan, A.M.2
Wold, M.S.3
-
11
-
-
2342618116
-
Phosphatidyl inositol 3-kinaselike serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21
-
Block WD, Yu Y, Lees-Miller SP. 2004. Phosphatidyl inositol 3-kinaselike serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21. Nucleic Acids Res. 32:997-1005.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 997-1005
-
-
Block, W.D.1
Yu, Y.2
Lees-Miller, S.P.3
-
12
-
-
25144467949
-
Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7
-
Boutell C, Canning M, Orr A, Everett RD. 2005. Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7. J. Virol. 79: 12342-12354.
-
(2005)
J. Virol.
, vol.79
, pp. 12342-12354
-
-
Boutell, C.1
Canning, M.2
Orr, A.3
Everett, R.D.4
-
13
-
-
3242701316
-
Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner
-
Boutell C, Everett RD. 2004. Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner. J. Virol. 78:8068-8077.
-
(2004)
J. Virol.
, vol.78
, pp. 8068-8077
-
-
Boutell, C.1
Everett, R.D.2
-
14
-
-
0019802153
-
Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication
-
Buller RM, Janik JE, Sebring ED, Rose JA. 1981. Herpes simplex virus types 1 and 2 completely help adenovirus-associated virus replication. J. Virol. 40:241-247.
-
(1981)
J. Virol.
, vol.40
, pp. 241-247
-
-
Buller, R.M.1
Janik, J.E.2
Sebring, E.D.3
Rose, J.A.4
-
15
-
-
33747889722
-
Role of non-homologous end joining (NHEJ) in maintaining genomic integrity
-
Burma S, Chen BP, Chen DJ. 2006. Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair 5:1042-1048.
-
(2006)
DNA Repair
, vol.5
, pp. 1042-1048
-
-
Burma, S.1
Chen, B.P.2
Chen, D.J.3
-
16
-
-
32844458451
-
Mechanisms of eukaryotic DNA double strand break repair
-
Cahill D, Connor B, Carney JP. 2006. Mechanisms of eukaryotic DNA double strand break repair. Front. Biosci. 11:1958 -1976.
-
(2006)
Front. Biosci.
, vol.11
, pp. 1958-1976
-
-
Cahill, D.1
Connor, B.2
Carney, J.P.3
-
17
-
-
0345732687
-
The Mre11 complex is required for ATM activation and the G[inf]2/M checkpoint
-
Carson CT, et al. 2003. The Mre11 complex is required for ATM activation and the G[inf]2/M checkpoint. EMBO J. 22:6610-6620.
-
(2003)
EMBO J
, vol.22
, pp. 6610-6620
-
-
Carson, C.T.1
-
18
-
-
77956623746
-
Differential effects of DNA doublestrand break repair pathways on single-strand and self-complementary adeno-associated virus vector genomes
-
Cataldi MP, McCarty DM. 2010. Differential effects of DNA doublestrand break repair pathways on single-strand and self-complementary adeno-associated virus vector genomes. J. Virol. 84:8673- 8682.
-
(2010)
J. Virol.
, vol.84
, pp. 8673-8682
-
-
Cataldi, M.P.1
McCarty, D.M.2
-
19
-
-
0037106180
-
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA doublestrand breaks
-
Chan DW, et al. 2002. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA doublestrand breaks. Genes Dev. 16:2333-2338.
-
(2002)
Genes Dev
, vol.16
, pp. 2333-2338
-
-
Chan, D.W.1
-
20
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
Chaturvedi P, et al. 1999. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 18: 4047-4054.
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
-
21
-
-
17644384427
-
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response toDNAdouble strand breaks
-
Chen BP, et al. 2005. Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response toDNAdouble strand breaks. J. Biol. Chem. 280:14709 -14715.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 14709-14715
-
-
Chen, B.P.1
-
22
-
-
3242879828
-
Chk1 in the DNA damage response: conserved roles from yeasts to mammals
-
Chen Y, Sanchez Y. 2004. Chk1 in the DNA damage response: conserved roles from yeasts to mammals. DNA Repair 3:1025-1032.
-
(2004)
DNA Repair
, vol.3
, pp. 1025-1032
-
-
Chen, Y.1
Sanchez, Y.2
-
23
-
-
78650859568
-
The effect of DNA-dependent protein kinase on adeno-associated virus replication
-
Choi YK, Nash K, Byrne BJ, Muzyczka N, Song S. 2010. The effect of DNA-dependent protein kinase on adeno-associated virus replication. PLoS One 5:e15073.
-
(2010)
PLoS One
, vol.5
-
-
Choi, Y.K.1
Nash, K.2
Byrne, B.J.3
Muzyczka, N.4
Song, S.5
-
24
-
-
61749102378
-
Cell-cycle control in the face of damage-a matter of life or death
-
Clarke PR, Allan LA. 2009. Cell-cycle control in the face of damage-a matter of life or death. Trends Cell Biol. 19:89 -98.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 89-98
-
-
Clarke, P.R.1
Allan, L.A.2
-
25
-
-
69249217762
-
Adeno-associated virus and adenovirus coinfection induces a cellular DNA damage and repair response via redundant phosphatidylinositol 3-like kinase pathways
-
Collaco RF, Bevington JM, Bhrigu V, Kalman-Maltese V, Trempe JP. 2009. Adeno-associated virus and adenovirus coinfection induces a cellular DNA damage and repair response via redundant phosphatidylinositol 3-like kinase pathways. Virology 392:24 -33.
-
(2009)
Virology
, vol.392
, pp. 24-33
-
-
Collaco, R.F.1
Bevington, J.M.2
Bhrigu, V.3
Kalman-Maltese, V.4
Trempe, J.P.5
-
26
-
-
1942437440
-
Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase
-
Dart DA, Adams KE, Akerman I, Lakin ND. 2004. Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase. J. Biol. Chem. 279:16433-16440.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 16433-16440
-
-
Dart, D.A.1
Adams, K.E.2
Akerman, I.3
Lakin, N.D.4
-
27
-
-
70350306544
-
Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway
-
Daya S, Cortez N, Berns KI. 2009. Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway. J. Virol. 83:11655-11664.
-
(2009)
J. Virol.
, vol.83
, pp. 11655-11664
-
-
Daya, S.1
Cortez, N.2
Berns, K.I.3
-
28
-
-
0346365293
-
Spatial and temporal organization of adenoassociated virus DNA replication in live cells
-
Fraefel C, et al. 2004. Spatial and temporal organization of adenoassociated virus DNA replication in live cells. J. Virol. 78:389 -398.
-
(2004)
J. Virol.
, vol.78
, pp. 389-398
-
-
Fraefel, C.1
-
30
-
-
77950464714
-
Inhibition of herpes simplex virus type 1 replication by adeno-associated virus Rep proteins depends on their combined DNA-binding and ATPase/helicase activities
-
Glauser DL, et al. 2010. Inhibition of herpes simplex virus type 1 replication by adeno-associated virus Rep proteins depends on their combined DNA-binding and ATPase/helicase activities. J. Virol. 84: 3808-3824.
-
(2010)
J. Virol.
, vol.84
, pp. 3808-3824
-
-
Glauser, D.L.1
-
31
-
-
34247608619
-
Live covisualization of competing adenoassociated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction
-
Glauser DL, et al. 2007. Live covisualization of competing adenoassociated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction. J. Virol. 81:4732- 4743.
-
(2007)
J. Virol.
, vol.81
, pp. 4732-4743
-
-
Glauser, D.L.1
-
32
-
-
0034312277
-
Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts
-
Guo Z, Kumagai A, Wang SX, Dunphy WG. 2000. Requirement for Atr in phosphorylation of Chk1 and cell cycle regulation in response to DNA replication blocks and UV-damaged DNA in Xenopus egg extracts. Genes Dev. 14:2745-2756.
-
(2000)
Genes Dev
, vol.14
, pp. 2745-2756
-
-
Guo, Z.1
Kumagai, A.2
Wang, S.X.3
Dunphy, W.G.4
-
33
-
-
36749022214
-
The DNA damage response: ten years after
-
Harper JW, Elledge SJ. 2007. The DNA damage response: ten years after. Mol. Cell 28:739 -745.
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
34
-
-
0025299743
-
The adenoassociated virus rep gene suppresses herpes simplex virus-induced DNA amplification
-
Heilbronn R, Burkle A, Stephan S, Hzur Hausen. 1990. The adenoassociated virus rep gene suppresses herpes simplex virus-induced DNA amplification. J. Virol. 64:3012-3018.
-
(1990)
J. Virol.
, vol.64
, pp. 3012-3018
-
-
Heilbronn, R.1
Burkle, A.2
Stephan, S.3
Hausen, H.4
-
35
-
-
0344442392
-
ssDNA-dependent colocalization of adenoassociated virus Rep and herpes simplex virus ICP8 in nuclear replication domains
-
Heilbronn R, et al. 2003. ssDNA-dependent colocalization of adenoassociated virus Rep and herpes simplex virus ICP8 in nuclear replication domains. Nucleic Acids Res. 31:6206-6213.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6206-6213
-
-
Heilbronn, R.1
-
36
-
-
34249945536
-
DNA doublestrand break repair: from mechanistic understanding to cancer treatment
-
Helleday T, Lo J, van Gent DC, Engelward BP. 2007. DNA doublestrand break repair: from mechanistic understanding to cancer treatment. DNA Repair 6:923-935.
-
(2007)
DNA Repair
, vol.6
, pp. 923-935
-
-
Helleday, T.1
Lo, J.2
van Gent, D.C.3
Engelward, B.P.4
-
37
-
-
0026501651
-
Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells
-
Hunter LA, Samulski RJ. 1992. Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells. J. Virol. 66: 317-324.
-
(1992)
J. Virol.
, vol.66
, pp. 317-324
-
-
Hunter, L.A.1
Samulski, R.J.2
-
38
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson SP, Bartek J. 2009. The DNA-damage response in human biology and disease. Nature 461:1071-1078.
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
39
-
-
0017686751
-
Anatomy of herpes simplex virus DNA VIII Properties of the replicating DNA
-
Jacob RJ, Roizman B. 1977. Anatomy of herpes simplex virus DNA VIII. Properties of the replicating DNA. J. Virol. 23:394-411.
-
(1977)
J. Virol.
, vol.23
, pp. 394-411
-
-
Jacob, R.J.1
Roizman, B.2
-
40
-
-
0035814489
-
Inhibition of adenovirus cytotoxicity, replication, and E2a gene expression by adeno-associated virus
-
Jing XJ, Kalman-Maltese V, Cao X, Yang Q, Trempe JP. 2001. Inhibition of adenovirus cytotoxicity, replication, and E2a gene expression by adeno-associated virus. Virology 291:140 -151.
-
(2001)
Virology
, vol.291
, pp. 140-151
-
-
Jing, X.J.1
Kalman-Maltese, V.2
Cao, X.3
Yang, Q.4
Trempe, J.P.5
-
41
-
-
10644254331
-
Viral transport of DNA damage that mimics a stalled replication fork
-
Jurvansuu J, Raj K, Stasiak A, Beard P. 2005. Viral transport of DNA damage that mimics a stalled replication fork. J. Virol. 79:569 -580.
-
(2005)
J. Virol.
, vol.79
, pp. 569-580
-
-
Jurvansuu, J.1
Raj, K.2
Stasiak, A.3
Beard, P.4
-
43
-
-
0034437671
-
Multiple signaling pathways involving ATM
-
Kastan MB, Lim DS, Kim ST, Xu B, Canman C. 2000. Multiple signaling pathways involving ATM. Cold Spring Harb. Symp. Quant. Biol. 65:521-526.
-
(2000)
Cold Spring Harb. Symp. Quant. Biol.
, vol.65
, pp. 521-526
-
-
Kastan, M.B.1
Lim, D.S.2
Kim, S.T.3
Xu, B.4
Canman, C.5
-
44
-
-
0028894254
-
Se- quence elements of the adeno-associated virus rep gene required for suppression of herpes-simplex-virus-inducedDNAamplification
-
Kleinschmidt JA, Mohler M, Weindler FW, Heilbronn R. 1995. Se-quence elements of the adeno-associated virus rep gene required for suppression of herpes-simplex-virus-inducedDNAamplification. Virology 206:254 -262.
-
(1995)
Virology
, vol.206
, pp. 254-262
-
-
Kleinschmidt, J.A.1
Mohler, M.2
Weindler, F.W.3
Heilbronn, R.4
-
45
-
-
68049084674
-
Breaking the chains: structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S. 2009. Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell Biol. 10: 550-563.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
46
-
-
0033536164
-
The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53
-
Lakin ND, Hann BC, Jackson SP. 1999. The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53. Oncogene 18:3989 -3995.
-
(1999)
Oncogene
, vol.18
, pp. 3989-3995
-
-
Lakin, N.D.1
Hann, B.C.2
Jackson, S.P.3
-
47
-
-
77955841725
-
The MRN complex in double-strand break repair and telomere maintenance
-
Lamarche BJ, Orazio NI, Weitzman MD. 2010. The MRN complex in double-strand break repair and telomere maintenance. FEBS Lett. 584: 3682-3695.
-
(2010)
FEBS Lett
, vol.584
, pp. 3682-3695
-
-
Lamarche, B.J.1
Orazio, N.I.2
Weitzman, M.D.3
-
48
-
-
0029798373
-
Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0
-
Lees-Miller SP, et al. 1996. Attenuation of DNA-dependent protein kinase activity and its catalytic subunit by the herpes simplex virus type 1 transactivator ICP0. J. Virol. 70:7471-7477.
-
(1996)
J. Virol.
, vol.70
, pp. 7471-7477
-
-
Lees-Miller, S.P.1
-
49
-
-
0026687883
-
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53
-
Lees-Miller SP, Sakaguchi K, Ullrich SJ, Appella E, Anderson CW. 1992. Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. Mol. Cell. Biol. 12:5041-5049.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5041-5049
-
-
Lees-Miller, S.P.1
Sakaguchi, K.2
Ullrich, S.J.3
Appella, E.4
Anderson, C.W.5
-
50
-
-
15744386741
-
Regulation of CHK2 by DNA-dependent protein kinase
-
Li J, Stern DF. 2005. Regulation of CHK2 by DNA-dependent protein kinase. J. Biol. Chem. 280:12041-12050.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12041-12050
-
-
Li, J.1
Stern, D.F.2
-
51
-
-
17644401351
-
DNA repair proteins affect the lifecycle of herpes simplex virus 1
-
Lilley CE, Carson CT, Muotri AR, Gage FH, Weitzman MD. 2005. DNA repair proteins affect the lifecycle of herpes simplex virus 1. Proc. Natl. Acad. Sci. U. S. A. 102:5844 -5849.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 5844-5849
-
-
Lilley, C.E.1
Carson, C.T.2
Muotri, A.R.3
Gage, F.H.4
Weitzman, M.D.5
-
52
-
-
0033643006
-
Molecular biology of adeno-associated viruses
-
Linden RM, Berns KI. 2000. Molecular biology of adeno-associated viruses. Contrib. Microbiol. 4:68-84.
-
(2000)
Contrib. Microbiol.
, vol.4
, pp. 68-84
-
-
Linden, R.M.1
Berns, K.I.2
-
53
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
-
Liu Q, et al. 2000. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev. 14: 1448-1459.
-
(2000)
Genes Dev
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
-
54
-
-
79960467426
-
ATR autophosphorylation as a molecular switch for checkpoint activation
-
Liu S, et al. 2011. ATR autophosphorylation as a molecular switch for checkpoint activation. Mol. Cell 43:192-202.
-
(2011)
Mol. Cell
, vol.43
, pp. 192-202
-
-
Liu, S.1
-
55
-
-
68249113593
-
Common mechanisms of PIKK regulation
-
Lovejoy CA, Cortez D. 2009. Common mechanisms of PIKK regulation. DNA Repair 8:1004 -1008.
-
(2009)
DNA Repair
, vol.8
, pp. 1004-1008
-
-
Lovejoy, C.A.1
Cortez, D.2
-
56
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, Elledge SJ. 1998. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 282:1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
57
-
-
0034641724
-
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S, et al. 2000. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc. Natl. Acad. Sci. U. S. A. 97:10389 -10394.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 10389-10394
-
-
Matsuoka, S.1
-
58
-
-
78049517168
-
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled
-
Mohni KN, Livingston CM, Cortez D, Weller SK. 2010. ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled. J. Virol. 84:12152-12164.
-
(2010)
J. Virol.
, vol.84
, pp. 12152-12164
-
-
Mohni, K.N.1
Livingston, C.M.2
Cortez, D.3
Weller, S.K.4
-
59
-
-
51849114713
-
Activation of ATR and related PIKKs
-
Mordes DA, Cortez D. 2008. Activation of ATR and related PIKKs. Cell Cycle 7:2809 -2812.
-
(2008)
Cell Cycle
, vol.7
, pp. 2809-2812
-
-
Mordes, D.A.1
Cortez, D.2
-
60
-
-
39649099566
-
Ku, Artemis, and ataxia-telangiectasia-mutated: signalling networks in DNA damage
-
Morio T, Kim H. 2008. Ku, Artemis, and ataxia-telangiectasia-mutated: signalling networks in DNA damage. Int. J. Biochem. Cell Biol. 40: 598-603.
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 598-603
-
-
Morio, T.1
Kim, H.2
-
61
-
-
0036349412
-
Characterization of adeno-associated virus rep protein inhibition of adenovirus E2a gene expression
-
Nada S, Trempe JP. 2002. Characterization of adeno-associated virus rep protein inhibition of adenovirus E2a gene expression. Virology 293: 345-355.
-
(2002)
Virology
, vol.293
, pp. 345-355
-
-
Nada, S.1
Trempe, J.P.2
-
62
-
-
79957690359
-
ATR signalling: more than meeting at the fork
-
Nam EA, Cortez D. 2011. ATR signalling: more than meeting at the fork. Biochem. J. 436:527-536.
-
(2011)
Biochem. J.
, vol.436
, pp. 527-536
-
-
Nam, E.A.1
Cortez, D.2
-
63
-
-
58149376502
-
Identification of cellular proteins that interact with the adeno-associated virus Rep protein
-
Nash K, Chen W, Salganik M, Muzyczka N. 2009. Identification of cellular proteins that interact with the adeno-associated virus Rep protein. J. Virol. 83:454-469.
-
(2009)
J. Virol.
, vol.83
, pp. 454-469
-
-
Nash, K.1
Chen, W.2
Salganik, M.3
Muzyczka, N.4
-
64
-
-
0031901455
-
Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection
-
Ni TH, et al. 1998. Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection. J. Virol. 72: 2777-2787.
-
(1998)
J. Virol.
, vol.72
, pp. 2777-2787
-
-
Ni, T.H.1
-
65
-
-
77956644782
-
Identification of Rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments
-
Nicolas A, et al. 2010. Identification of Rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J. Virol. 84:8871- 8887.
-
(2010)
J. Virol.
, vol.84
, pp. 8871-8887
-
-
Nicolas, A.1
-
66
-
-
70349099568
-
DNA double-strand breaks: their production, recognition, and repair in eukaryotes
-
Ohnishi T, Mori E, Takahashi A. 2009. DNA double-strand breaks: their production, recognition, and repair in eukaryotes. Mutat. Res. 669: 8-12.
-
(2009)
Mutat. Res.
, vol.669
, pp. 8-12
-
-
Ohnishi, T.1
Mori, E.2
Takahashi, A.3
-
67
-
-
0032889431
-
Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasomedependent degradation of the catalytic subunit of DNA-dependent protein kinase
-
Parkinson J, Lees-Miller SP, Everett RD. 1999. Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasomedependent degradation of the catalytic subunit of DNA-dependent protein kinase. J. Virol. 73:650-657.
-
(1999)
J. Virol.
, vol.73
, pp. 650-657
-
-
Parkinson, J.1
Lees-Miller, S.P.2
Everett, R.D.3
-
68
-
-
0035974901
-
Virus-mediated killing of cells that lack p53 activity
-
Raj K, Ogston P, Beard P. 2001. Virus-mediated killing of cells that lack p53 activity. Nature 412:914 -917.
-
(2001)
Nature
, vol.412
, pp. 914-917
-
-
Raj, K.1
Ogston, P.2
Beard, P.3
-
69
-
-
63749131243
-
Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2
-
Reinhardt HC, Yaffe MB. 2009. Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Curr. Opin. Cell Biol. 21:245-255.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 245-255
-
-
Reinhardt, H.C.1
Yaffe, M.B.2
-
72
-
-
0026070440
-
Targeted integration of adeno-associated virus (AAV) into human chromosome 19
-
Samulski RJ, et al. 1991. Targeted integration of adeno-associated virus (AAV) into human chromosome 19. EMBO J. 10:3941-3950.
-
(1991)
EMBO J
, vol.10
, pp. 3941-3950
-
-
Samulski, R.J.1
-
73
-
-
0034663781
-
Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb
-
Saudan P, Vlach J, Beard P. 2000. Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb. EMBO J. 19:4351- 4361.
-
(2000)
EMBO J.
, vol.19
, pp. 4351-4361
-
-
Saudan, P.1
Vlach, J.2
Beard, P.3
-
74
-
-
0028281022
-
The tumor suppressive properties of adenoassociated viruses
-
Schlehofer JR. 1994. The tumor suppressive properties of adenoassociated viruses. Mutat. Res. 305:303-313.
-
(1994)
Mutat. Res.
, vol.305
, pp. 303-313
-
-
Schlehofer, J.R.1
-
75
-
-
66149143110
-
Adenoassociated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase
-
Schwartz RA, Carson CT, Schuberth C, Weitzman MD. 2009. Adenoassociated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. J. Virol. 83:6269-6278.
-
(2009)
J. Virol.
, vol.83
, pp. 6269-6278
-
-
Schwartz, R.A.1
Carson, C.T.2
Schuberth, C.3
Weitzman, M.D.4
-
76
-
-
24044489232
-
Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection
-
Shirata N, et al. 2005. Activation of ataxia telangiectasia-mutated DNA damage checkpoint signal transduction elicited by herpes simplex virus infection. J. Biol. Chem. 280:30336-30341.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30336-30341
-
-
Shirata, N.1
-
77
-
-
1242319264
-
DNA-dependent PK inhibits adeno-associated virus DNA integration
-
Song S, et al. 2004. DNA-dependent PK inhibits adeno-associated virus DNA integration. Proc. Natl. Acad. Sci. U. S. A. 101:2112-2116.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2112-2116
-
-
Song, S.1
-
78
-
-
0037130170
-
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
-
Stracker TH, Carson CT, Weitzman MD. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348 -352.
-
(2002)
Nature
, vol.418
, pp. 348-352
-
-
Stracker, T.H.1
Carson, C.T.2
Weitzman, M.D.3
-
79
-
-
10744231280
-
The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication
-
Stracker TH, et al. 2004. The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication. J. Virol. 78:441- 453.
-
(2004)
J. Virol.
, vol.78
, pp. 441-453
-
-
Stracker, T.H.1
-
81
-
-
2442653990
-
Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8
-
Taylor TJ, Knipe DM. 2004. Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J. Virol. 78:5856 -5866.
-
(2004)
J. Virol.
, vol.78
, pp. 5856-5866
-
-
Taylor, T.J.1
Knipe, D.M.2
-
82
-
-
0037903355
-
Herpes simplex virus replication compartments can form by coalescence of smaller compartments
-
Taylor TJ, McNamee EE, Day C, Knipe DM. 2003. Herpes simplex virus replication compartments can form by coalescence of smaller compartments. Virology 309:232-247.
-
(2003)
Virology
, vol.309
, pp. 232-247
-
-
Taylor, T.J.1
McNamee, E.E.2
Day, C.3
Knipe, D.M.4
-
83
-
-
0033637170
-
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
-
Tibbetts RS, et al. 2000. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev. 14: 2989-3002.
-
(2000)
Genes Dev
, vol.14
, pp. 2989-3002
-
-
Tibbetts, R.S.1
-
84
-
-
33746817450
-
Effects of adeno-associated virus on adenovirus replication and gene expression during coinfection
-
Timpe JM, Verrill KC, Trempe JP. 2006. Effects of adeno-associated virus on adenovirus replication and gene expression during coinfection. J. Virol. 80:7807-7815.
-
(2006)
J. Virol.
, vol.80
, pp. 7807-7815
-
-
Timpe, J.M.1
Verrill, K.C.2
Trempe, J.P.3
-
85
-
-
67349288164
-
Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells
-
Tomimatsu N, Mukherjee B, Burma S. 2009. Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells. EMBO Rep. 10:629-635.
-
(2009)
EMBO Rep
, vol.10
, pp. 629-635
-
-
Tomimatsu, N.1
Mukherjee, B.2
Burma, S.3
-
86
-
-
12944316615
-
The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest
-
Wang S, et al. 2000. The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest. Proc. Natl. Acad. Sci. U. S. A. 97:1584 -1588.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 1584-1588
-
-
Wang, S.1
-
88
-
-
0026523766
-
Phosphorylation sites in the amino-terminal region of mouse p53
-
Wang Y, Eckhart W. 1992. Phosphorylation sites in the amino-terminal region of mouse p53. Proc. Natl. Acad. Sci. U. S. A. 89:4231-4235.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 4231-4235
-
-
Wang, Y.1
Eckhart, W.2
-
89
-
-
77951974344
-
Dealing with DNA damage: relationships between checkpoint and repair pathways
-
Warmerdam DO, Kanaar R. 2010. Dealing with DNA damage: relationships between checkpoint and repair pathways. Mutat. Res. 704:2-11.
-
(2010)
Mutat. Res.
, vol.704
, pp. 2-11
-
-
Warmerdam, D.O.1
Kanaar, R.2
-
90
-
-
0025820474
-
A subset of herpes simplex virus replication genes provides helper functions for productive adenoassociated virus replication
-
Weindler FW, Heilbronn R. 1991. A subset of herpes simplex virus replication genes provides helper functions for productive adenoassociated virus replication. J. Virol. 65:2476-2483.
-
(1991)
J. Virol.
, vol.65
, pp. 2476-2483
-
-
Weindler, F.W.1
Heilbronn, R.2
-
91
-
-
0030058330
-
Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers
-
Weitzman MD, Fisher KJ, Wilson JM. 1996. Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers. J. Virol. 70:1845-1854.
-
(1996)
J. Virol.
, vol.70
, pp. 1845-1854
-
-
Weitzman, M.D.1
Fisher, K.J.2
Wilson, J.M.3
-
92
-
-
77957951602
-
Genomes in conflict: maintaining genome integrity during virus infection
-
Weitzman MD, Lilley CE, Chaurushiya MS. 2010. Genomes in conflict: maintaining genome integrity during virus infection. Annu. Rev. Microbiol. 64:61-81.
-
(2010)
Annu. Rev. Microbiol.
, vol.64
, pp. 61-81
-
-
Weitzman, M.D.1
Lilley, C.E.2
Chaurushiya, M.S.3
-
93
-
-
0026062090
-
Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells
-
Wilcock D, Lane DP. 1991. Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells. Nature 349:429-431.
-
(1991)
Nature
, vol.349
, pp. 429-431
-
-
Wilcock, D.1
Lane, D.P.2
-
94
-
-
33746871757
-
Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection
-
Wilkinson DE, Weller SK. 2006. Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection. J. Cell Sci. 119:2695-2703.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 2695-2703
-
-
Wilkinson, D.E.1
Weller, S.K.2
-
95
-
-
18744398124
-
Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection
-
Wilkinson DE, Weller SK. 2005. Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection. J. Virol. 79:7162-7171.
-
(2005)
J. Virol.
, vol.79
, pp. 7162-7171
-
-
Wilkinson, D.E.1
Weller, S.K.2
-
96
-
-
4644296028
-
Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response
-
Wilkinson DE, Weller SK. 2004. Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. J. Virol. 78:4783- 4796.
-
(2004)
J. Virol.
, vol.78
, pp. 4783-4796
-
-
Wilkinson, D.E.1
Weller, S.K.2
-
97
-
-
0030908093
-
Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism
-
Wold MS. 1997. Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66:61-92.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 61-92
-
-
Wold, M.S.1
-
98
-
-
0023992803
-
Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA
-
Wold MS, Kelly T. 1988. Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA. Proc. Natl. Acad. Sci. U. S. A. 85:2523-2527.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 2523-2527
-
-
Wold, M.S.1
Kelly, T.2
-
99
-
-
33845604556
-
DNA double-strand break repair: all's well that ends well
-
Wyman C, Kanaar R. 2006. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40:363-383.
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
100
-
-
0028926589
-
Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins
-
Yang Q, Chen F, Ross J, Trempe JP. 1995. Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins. Virology 207:246 -250.
-
(1995)
Virology
, vol.207
, pp. 246-250
-
-
Yang, Q.1
Chen, F.2
Ross, J.3
Trempe, J.P.4
-
101
-
-
0028228449
-
Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins
-
Yang Q, Chen F, Trempe JP. 1994. Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins. J. Virol. 68: 4847-4856.
-
(1994)
J. Virol.
, vol.68
, pp. 4847-4856
-
-
Yang, Q.1
Chen, F.2
Trempe, J.P.3
-
102
-
-
0034711045
-
Functional characterization of zincfinger motif in redox regulation of RPA-ssDNA interaction
-
You JS, Wang M, Lee SH. 2000. Functional characterization of zincfinger motif in redox regulation of RPA-ssDNA interaction. Biochemistry 39:12953-12958.
-
(2000)
Biochemistry
, vol.39
, pp. 12953-12958
-
-
You, J.S.1
Wang, M.2
Lee, S.H.3
-
103
-
-
20744436198
-
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
-
You Z, Chahwan C, Bailis J, Hunter T, Russell P. 2005. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol. Cell. Biol. 25:5363-5379.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5363-5379
-
-
You, Z.1
Chahwan, C.2
Bailis, J.3
Hunter, T.4
Russell, P.5
-
104
-
-
0030810633
-
Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells
-
Zernik-Kobak M, Vasunia K, Connelly M, Anderson CW, Dixon K. 1997. Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells. J. Biol. Chem. 272:23896 -23904.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23896-23904
-
-
Zernik-Kobak, M.1
Vasunia, K.2
Connelly, M.3
Anderson, C.W.4
Dixon, K.5
-
105
-
-
0034967556
-
ATR- mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H, Piwnica-Worms H. 2001. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol. Cell. Biol. 21:4129-4139.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
106
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L, Elledge SJ. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
107
-
-
33745607897
-
Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses
-
Zou Y, Liu Y, Wu X, Shell SM. 2006. Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses. J. Cell. Physiol. 208:267-273.
-
(2006)
J. Cell. Physiol.
, vol.208
, pp. 267-273
-
-
Zou, Y.1
Liu, Y.2
Wu, X.3
Shell, S.M.4
|