-
1
-
-
0027468265
-
Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks
-
Blier PR, Griffith AJ, Craft J, Hardin JA (1993) Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J Biol Chem 268: 7594-7601.
-
(1993)
J Biol Chem
, vol.268
, pp. 7594-7601
-
-
Blier, P.R.1
Griffith, A.J.2
Craft, J.3
Hardin, J.A.4
-
2
-
-
0026570651
-
Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA
-
Griffith AJ, Blier PR, Mimori T, Hardin JA (1992) Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J Biol Chem 267: 331-338.
-
(1992)
J Biol Chem
, vol.267
, pp. 331-338
-
-
Griffith, A.J.1
Blier, P.R.2
Mimori, T.3
Hardin, J.A.4
-
3
-
-
0035833552
-
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
-
Walker JR, Corpina RA, Goldberg J (2001) Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412: 607-614.
-
(2001)
Nature
, vol.412
, pp. 607-614
-
-
Walker, J.R.1
Corpina, R.A.2
Goldberg, J.3
-
4
-
-
0034714199
-
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase
-
Chen L, Trujillo K, Sung P, Tomkinson AE (2000) Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. J Biol Chem 275: 26196-26205.
-
(2000)
J Biol Chem
, vol.275
, pp. 26196-26205
-
-
Chen, L.1
Trujillo, K.2
Sung, P.3
Tomkinson, A.E.4
-
5
-
-
14844292557
-
DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks
-
Drouet J, Delteil C, Lefrancois J, Concannon P, Salles B, et al. (2005) DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. J Biol Chem 280: 7060-7069.
-
(2005)
J Biol Chem
, vol.280
, pp. 7060-7069
-
-
Drouet, J.1
Delteil, C.2
Lefrancois, J.3
Concannon, P.4
Salles, B.5
-
6
-
-
0037155703
-
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
-
Ma Y, Pannicke U, Schwarz K, Lieber MR (2002) Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108: 781-794.
-
(2002)
Cell
, vol.108
, pp. 781-794
-
-
Ma, Y.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
7
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous D, Callebaut I, de Chasseval R, Corneo B, Cavazzana-Calvo M, et al. (2001) Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105: 177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
Callebaut, I.2
de Chasseval, R.3
Corneo, B.4
Cavazzana-Calvo, M.5
-
8
-
-
0037106180
-
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
-
Chan DW, Chen BP, Prithivirajsingh S, Kurimasa A, Story MD, et al. (2002) Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev 16: 2333-2338.
-
(2002)
Genes Dev
, vol.16
, pp. 2333-2338
-
-
Chan, D.W.1
Chen, B.P.2
Prithivirajsingh, S.3
Kurimasa, A.4
Story, M.D.5
-
9
-
-
17644384427
-
Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
-
Chen BP, Chan DW, Kobayashi J, Burma S, Asaithamby A, et al. (2005) Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J Biol Chem 280: 14709-14715.
-
(2005)
J Biol Chem
, vol.280
, pp. 14709-14715
-
-
Chen, B.P.1
Chan, D.W.2
Kobayashi, J.3
Burma, S.4
Asaithamby, A.5
-
10
-
-
20444475018
-
DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs
-
Shinohara ET, Geng L, Tan J, Chen H, Shir Y, et al. (2005) DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs. Cancer Res 65: 4987-4992.
-
(2005)
Cancer Res
, vol.65
, pp. 4987-4992
-
-
Shinohara, E.T.1
Geng, L.2
Tan, J.3
Chen, H.4
Shir, Y.5
-
11
-
-
20144373772
-
Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy
-
Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, et al. (2005) Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy. Cancer Res 65: 4368-4375.
-
(2005)
Cancer Res
, vol.65
, pp. 4368-4375
-
-
Daido, S.1
Yamamoto, A.2
Fujiwara, K.3
Sawaya, R.4
Kondo, S.5
-
12
-
-
0029803485
-
Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells
-
Boulton S, Kyle S, Yalcintepe L, Durkacz BW (1996) Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells. Carcinogenesis 17: 2285-2290.
-
(1996)
Carcinogenesis
, vol.17
, pp. 2285-2290
-
-
Boulton, S.1
Kyle, S.2
Yalcintepe, L.3
Durkacz, B.W.4
-
13
-
-
0030066023
-
The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage
-
Price BD, Youmell MB (1996) The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage. Cancer Res 56: 246- 250.
-
(1996)
Cancer Res
, vol.56
, pp. 246-250
-
-
Price, B.D.1
Youmell, M.B.2
-
14
-
-
0033152759
-
Competitive and noncompetitive inhibition of the DNA-dependent protein kinase
-
Izzard RA, Jackson SP, Smith GC (1999) Competitive and noncompetitive inhibition of the DNA-dependent protein kinase. Cancer Res 59: 2581-2586.
-
(1999)
Cancer Res
, vol.59
, pp. 2581-2586
-
-
Izzard, R.A.1
Jackson, S.P.2
Smith, G.C.3
-
15
-
-
0037124322
-
DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53
-
Woo RA, Jack MT, Xu Y, Burma S, Chen DJ, et al. (2002) DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53. Embo J 21: 3000-3008.
-
(2002)
Embo J
, vol.21
, pp. 3000-3008
-
-
Woo, R.A.1
Jack, M.T.2
Xu, Y.3
Burma, S.4
Chen, D.J.5
-
16
-
-
12344324602
-
DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70
-
Yamaguchi S, Hasegawa M, Aizawa S, Tanaka K, Yoshida K, et al. (2005) DNA-dependent protein kinase enhances DNA damage-induced apoptosis in association with Friend gp70. Leuk Res 29: 307-316.
-
(2005)
Leuk Res
, vol.29
, pp. 307-316
-
-
Yamaguchi, S.1
Hasegawa, M.2
Aizawa, S.3
Tanaka, K.4
Yoshida, K.5
-
17
-
-
0031795922
-
Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: Implications for apoptosis
-
Bharti A, Kraeft SK, Gounder M, Pandey P, Jin S, et al. (1998) Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis. Mol Cell Biol 18: 6719-6728.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6719-6728
-
-
Bharti, A.1
Kraeft, S.K.2
Gounder, M.3
Pandey, P.4
Jin, S.5
-
18
-
-
0034669104
-
Ku acts in a unique way at the mammalian telomere to prevent end joining
-
Hsu HL, Gilley D, Galande SA, Hande MP, Allen B, et al. (2000) Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev 14: 2807-2812.
-
(2000)
Genes Dev
, vol.14
, pp. 2807-2812
-
-
Hsu, H.L.1
Gilley, D.2
Galande, S.A.3
Hande, M.P.4
Allen, B.5
-
19
-
-
0000595683
-
-
Fields B, ed. Fields Virology. Philadelphia, PA: Raven Press
-
Berns KI (1996) Parvoviridae: The Viruses and their replication. In: Fields B, ed. Fields Virology. Philadelphia, PA: Raven Press. pp 2173-2197.
-
(1996)
Parvoviridae: The Viruses and Their Replication
, pp. 2173-2197
-
-
Berns, K.I.1
-
20
-
-
0025362618
-
The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity
-
Im DS, Muzyczka N (1990) The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity. Cell 61: 447-457.
-
(1990)
Cell
, vol.61
, pp. 447-457
-
-
Im, D.S.1
Muzyczka, N.2
-
21
-
-
0032853990
-
Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification
-
Brister JR, Muzyczka N (1999) Rep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification. J Virol 73: 9325-9336.
-
(1999)
J Virol
, vol.73
, pp. 9325-9336
-
-
Brister, J.R.1
Muzyczka, N.2
-
22
-
-
0033899961
-
Mechanism of Rep-mediated adeno-associated virus origin nicking
-
Brister JR, Muzyczka N (2000) Mechanism of Rep-mediated adeno-associated virus origin nicking. J Virol 74: 7762-7771.
-
(2000)
J Virol
, vol.74
, pp. 7762-7771
-
-
Brister, J.R.1
Muzyczka, N.2
-
23
-
-
0028307303
-
Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA
-
Weitzman MD, Kyostio SR, Kotin RM, Owens RA (1994) Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA. Proc Natl Acad Sci U S A 91: 5808-5812.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 5808-5812
-
-
Weitzman, M.D.1
Kyostio, S.R.2
Kotin, R.M.3
Owens, R.A.4
-
24
-
-
0021257303
-
Genetics of adeno-associated virus: Isolation and preliminary characterization of adeno-associated virus type 2 mutants
-
Hermonat PL, Labow MA, Wright R, Berns KI, Muzyczka N (1984) Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants. J Virol 51: 329-339.
-
(1984)
J Virol
, vol.51
, pp. 329-339
-
-
Hermonat, P.L.1
Labow, M.A.2
Wright, R.3
Berns, K.I.4
Muzyczka, N.5
-
25
-
-
0028006264
-
In vitro replication of adeno-associated virus DNA
-
Ni TH, Zhou X, McCarty DM, Zolotukhin I, Muzyczka N (1994) In vitro replication of adeno-associated virus DNA. J Virol 68: 1128-1138.
-
(1994)
J Virol
, vol.68
, pp. 1128-1138
-
-
Ni, T.H.1
Zhou, X.2
McCarty, D.M.3
Zolotukhin, I.4
Muzyczka, N.5
-
26
-
-
0028050094
-
Adeno-associated virus DNA replication in vitro: Activation by a maltose binding protein/Rep 68 fusion protein
-
Ward P, Urcelay E, Kotin R, Safer B, Berns KI (1994) Adeno-associated virus DNA replication in vitro: activation by a maltose binding protein/Rep 68 fusion protein. J Virol 68: 6029-6037.
-
(1994)
J Virol
, vol.68
, pp. 6029-6037
-
-
Ward, P.1
Urcelay, E.2
Kotin, R.3
Safer, B.4
Berns, K.I.5
-
27
-
-
0029888985
-
In vitro replication of adeno-associated virus DNA: Enhancement by extracts from adenovirus-infected HeLa cells
-
Ward P, Berns KI (1996) In vitro replication of adeno-associated virus DNA: enhancement by extracts from adenovirus-infected HeLa cells. J Virol 70: 4495-4501.
-
(1996)
J Virol
, vol.70
, pp. 4495-4501
-
-
Ward, P.1
Berns, K.I.2
-
28
-
-
0024428509
-
Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein
-
Beaton A, Palumbo P, Berns KI (1989) Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein. J Virol 63: 4450-4454.
-
(1989)
J Virol
, vol.63
, pp. 4450-4454
-
-
Beaton, A.1
Palumbo, P.2
Berns, K.I.3
-
29
-
-
0022451185
-
Positive and negative autoregulation of the adeno-associated virus type 2 genome
-
Labow MA, Hermonat PL, Berns KI (1986) Positive and negative autoregulation of the adeno-associated virus type 2 genome. J Virol 60: 251-258.
-
(1986)
J Virol
, vol.60
, pp. 251-258
-
-
Labow, M.A.1
Hermonat, P.L.2
Berns, K.I.3
-
30
-
-
0031014018
-
The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection
-
Pereira DJ, McCarty DM, Muzyczka N (1997) The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection. J Virol 71: 1079-1088.
-
(1997)
J Virol
, vol.71
, pp. 1079-1088
-
-
Pereira, D.J.1
McCarty, D.M.2
Muzyczka, N.3
-
31
-
-
0030958815
-
The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation
-
Pereira DJ, Muzyczka N (1997) The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation. J Virol 71: 4300-4309.
-
(1997)
J Virol
, vol.71
, pp. 4300-4309
-
-
Pereira, D.J.1
Muzyczka, N.2
-
32
-
-
0031048047
-
The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter
-
Pereira DJ, Muzyczka N (1997) The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter. J Virol 71: 1747-1756.
-
(1997)
J Virol
, vol.71
, pp. 1747-1756
-
-
Pereira, D.J.1
Muzyczka, N.2
-
33
-
-
0025946426
-
Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein
-
McCarty DM, Christensen M, Muzyczka N (1991) Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein. J Virol 65: 2936-2945.
-
(1991)
J Virol
, vol.65
, pp. 2936-2945
-
-
McCarty, D.M.1
Christensen, M.2
Muzyczka, N.3
-
34
-
-
0030862039
-
Control of adeno-associated virus type 2 cap gene expression: Relative influence of helper virus, terminal repeats, and Rep proteins
-
Weger S, Wistuba A, Grimm D, Kleinschmidt JA (1997) Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins. J Virol 71: 8437-8447.
-
(1997)
J Virol
, vol.71
, pp. 8437-8447
-
-
Weger, S.1
Wistuba, A.2
Grimm, D.3
Kleinschmidt, J.A.4
-
35
-
-
0032826095
-
Adeno-associated virus type 2 protein interactions: Formation of pre-encapsidation complexes
-
Dubielzig R, King JA, Weger S, Kern A, Kleinschmidt JA (1999) Adeno-associated virus type 2 protein interactions: formation of pre-encapsidation complexes. J Virol 73: 8989-8998.
-
(1999)
J Virol
, vol.73
, pp. 8989-8998
-
-
Dubielzig, R.1
King, J.A.2
Weger, S.3
Kern, A.4
Kleinschmidt, J.A.5
-
36
-
-
0035875669
-
DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids
-
King JA, Dubielzig R, Grimm D, Kleinschmidt JA (2001) DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids. EMBO J 20: 3282-3291.
-
(2001)
EMBO J
, vol.20
, pp. 3282-3291
-
-
King, J.A.1
Dubielzig, R.2
Grimm, D.3
Kleinschmidt, J.A.4
-
37
-
-
0025214094
-
Site-specific integration by adeno-associated virus
-
Kotin RM, Siniscalco M, Samulski RJ, Zhu XD, Hunter L, et al. (1990) Site-specific integration by adeno-associated virus. Proc Natl Acad Sci U S A 87: 2211-2215.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2211-2215
-
-
Kotin, R.M.1
Siniscalco, M.2
Samulski, R.J.3
Zhu, X.D.4
Hunter, L.5
-
38
-
-
0026070440
-
Targeted integration of adeno-associated virus (AAV) into human chromosome 19
-
Samulski RJ, Zhu X, Xiao X, Brook JD, Housman DE, et al. (1991) Targeted integration of adeno-associated virus (AAV) into human chromosome 19. Embo J 10: 3941-3950.
-
(1991)
Embo J
, vol.10
, pp. 3941-3950
-
-
Samulski, R.J.1
Zhu, X.2
Xiao, X.3
Brook, J.D.4
Housman, D.E.5
-
39
-
-
0030896361
-
Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome
-
Balague C, Kalla M, Zhang WW (1997) Adeno-associated virus Rep78 protein and terminal repeats enhance integration of DNA sequences into the cellular genome. J Virol 71: 3299-3306.
-
(1997)
J Virol
, vol.71
, pp. 3299-3306
-
-
Balague, C.1
Kalla, M.2
Zhang, W.W.3
-
40
-
-
0037125986
-
A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19
-
Philpott NJ, Gomos J, Berns KI, Falck-Pedersen E (2002) A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19. Proc Natl Acad Sci U S A 99: 12381-12385.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12381-12385
-
-
Philpott, N.J.1
Gomos, J.2
Berns, K.I.3
Falck-Pedersen, E.4
-
41
-
-
34249801792
-
Purification of host cell enzymes involved in adeno-associated virus DNA replication
-
Nash K, Chen W, McDonald WF, Zhou X, Muzyczka N (2007) Purification of host cell enzymes involved in adeno-associated virus DNA replication. J Virol 81: 5777-5787.
-
(2007)
J Virol
, vol.81
, pp. 5777-5787
-
-
Nash, K.1
Chen, W.2
McDonald, W.F.3
Zhou, X.4
Muzyczka, N.5
-
42
-
-
38349096769
-
Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins
-
Nash K, Chen W, Muzyczka N (2008) Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins. J Virol 82: 1458-1464.
-
(2008)
J Virol
, vol.82
, pp. 1458-1464
-
-
Nash, K.1
Chen, W.2
Muzyczka, N.3
-
43
-
-
0031901455
-
Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection
-
Ni TH, McDonald WF, Zolotukhin I, Melendy T, Waga S, et al. (1998) Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection. J Virol 72: 2777-2787.
-
(1998)
J Virol
, vol.72
, pp. 2777-2787
-
-
Ni, T.H.1
McDonald, W.F.2
Zolotukhin, I.3
Melendy, T.4
Waga, S.5
-
44
-
-
10744231280
-
The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication
-
Stracker TH, Cassell GD, Ward P, Loo YM, van Breukelen B, et al. (2004) The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication. J Virol 78: 441-453.
-
(2004)
J Virol
, vol.78
, pp. 441-453
-
-
Stracker, T.H.1
Cassell, G.D.2
Ward, P.3
Loo, Y.M.4
van Breukelen, B.5
-
45
-
-
58149376502
-
Identification of cellular proteins that interact with the adeno-associated virus rep protein
-
Nash K, Chen W, Salganik M, Muzyczka N (2009) Identification of cellular proteins that interact with the adeno-associated virus rep protein. J Virol 83: 454-469.
-
(2009)
J Virol
, vol.83
, pp. 454-469
-
-
Nash, K.1
Chen, W.2
Salganik, M.3
Muzyczka, N.4
-
46
-
-
0025820474
-
A subset of herpes simplex virus replication genes provides helper functions for productive adeno-associated virus replication
-
Weindler FW, Heilbronn R (1991) A subset of herpes simplex virus replication genes provides helper functions for productive adeno-associated virus replication. J Virol 65: 2476-2483.
-
(1991)
J Virol
, vol.65
, pp. 2476-2483
-
-
Weindler, F.W.1
Heilbronn, R.2
-
47
-
-
33646733648
-
Role of the herpes simplex virus helicase-primase complex during adeno-associated virus DNA replication
-
Slanina H, Weger S, Stow ND, Kuhrs A, Heilbronn R (2006) Role of the herpes simplex virus helicase-primase complex during adeno-associated virus DNA replication. J Virol 80: 5241-5250.
-
(2006)
J Virol
, vol.80
, pp. 5241-5250
-
-
Slanina, H.1
Weger, S.2
Stow, N.D.3
Kuhrs, A.4
Heilbronn, R.5
-
48
-
-
63449112088
-
Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events
-
Alazard-Dany N, Nicolas A, Ploquin A, Strasser R, Greco A, et al. (2009) Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events. PLoS Pathog 5: e1000340.
-
(2009)
PLoS Pathog
, vol.5
-
-
Alazard-Dany, N.1
Nicolas, A.2
Ploquin, A.3
Strasser, R.4
Greco, A.5
-
49
-
-
13644257036
-
Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines
-
Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, et al. (2004) Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines. J Gene Med 6: 555-564.
-
(2004)
J Gene Med
, vol.6
, pp. 555-564
-
-
Toublanc, E.1
Benraiss, A.2
Bonnin, D.3
Blouin, V.4
Brument, N.5
-
50
-
-
13144305062
-
Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors
-
Song S, Morgan M, Ellis T, Poirier A, Chesnut K, et al. (1998) Sustained secretion of human alpha-1-antitrypsin from murine muscle transduced with adeno-associated virus vectors. Proc Natl Acad Sci U S A 95: 14384-14388.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 14384-14388
-
-
Song, S.1
Morgan, M.2
Ellis, T.3
Poirier, A.4
Chesnut, K.5
-
51
-
-
1242319264
-
DNA-dependent PK inhibits adeno-associated virus DNA integration
-
Song S, Lu Y, Choi YK, Han Y, Tang Q, et al. (2004) DNA-dependent PK inhibits adeno-associated virus DNA integration. Proc Natl Acad Sci U S A 101: 2112-2116.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2112-2116
-
-
Song, S.1
Lu, Y.2
Choi, Y.K.3
Han, Y.4
Tang, Q.5
-
52
-
-
0030827207
-
Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap
-
Conway JE, Zolotukhin S, Muzyczka N, Hayward GS, Byrne BJ (1997) Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap. J Virol 71: 8780-8789.
-
(1997)
J Virol
, vol.71
, pp. 8780-8789
-
-
Conway, J.E.1
Zolotukhin, S.2
Muzyczka, N.3
Hayward, G.S.4
Byrne, B.J.5
-
53
-
-
0024697626
-
The inhibition of prostaglandin E1-induced corneal neovascularization by steroid eye drops
-
Chang CT, Chen YL, Lee SH, Lue CM, Lin MT (1989) The inhibition of prostaglandin E1-induced corneal neovascularization by steroid eye drops. Taiwan Yi Xue Hui Za Zhi 88: 707-711.
-
(1989)
Taiwan Yi Xue Hui Za Zhi
, vol.88
, pp. 707-711
-
-
Chang, C.T.1
Chen, Y.L.2
Lee, S.H.3
Lue, C.M.4
Lin, M.T.5
-
54
-
-
0025674625
-
Effects of PGE1 on platelet deformability
-
Chang YN, Hsu HT, Hung MS, Chang CL, Li JG, et al. (1990) Effects of PGE1 on platelet deformability. Chin J Physiol 33: 31-40.
-
(1990)
Chin J Physiol
, vol.33
, pp. 31-40
-
-
Chang, Y.N.1
Hsu, H.T.2
Hung, M.S.3
Chang, C.L.4
Li, J.G.5
-
55
-
-
0020086215
-
Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus
-
Laughlin CA, Jones N, Carter BJ (1982) Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus. J Virol 41: 868-876.
-
(1982)
J Virol
, vol.41
, pp. 868-876
-
-
Laughlin, C.A.1
Jones, N.2
Carter, B.J.3
-
56
-
-
34547946751
-
Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling
-
Jurvansuu J, Fragkos M, Ingemarsdotter C, Beard P (2007) Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling. J Mol Biol 372: 397-406.
-
(2007)
J Mol Biol
, vol.372
, pp. 397-406
-
-
Jurvansuu, J.1
Fragkos, M.2
Ingemarsdotter, C.3
Beard, P.4
-
57
-
-
10644254331
-
Viral transport of DNA damage that mimics a stalled replication fork
-
Jurvansuu J, Raj K, Stasiak A, Beard P (2005) Viral transport of DNA damage that mimics a stalled replication fork. J Virol 79: 569-580.
-
(2005)
J Virol
, vol.79
, pp. 569-580
-
-
Jurvansuu, J.1
Raj, K.2
Stasiak, A.3
Beard, P.4
-
58
-
-
66149143110
-
Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase
-
Schwartz RA, Carson CT, Schuberth C, Weitzman MD (2009) Adeno-associated virus replication induces a DNA damage response coordinated by DNA-dependent protein kinase. J Virol 83: 6269-6278.
-
(2009)
J Virol
, vol.83
, pp. 6269-6278
-
-
Schwartz, R.A.1
Carson, C.T.2
Schuberth, C.3
Weitzman, M.D.4
-
59
-
-
0032889431
-
Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase
-
Parkinson J, Lees-Miller SP, Everett RD (1999) Herpes simplex virus type 1 immediate-early protein vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase. J Virol 73: 650-657.
-
(1999)
J Virol
, vol.73
, pp. 650-657
-
-
Parkinson, J.1
Lees-Miller, S.P.2
Everett, R.D.3
-
60
-
-
0023018824
-
Latent infection of KB cells with adeno-associated virus type 2
-
Laughlin CA, Cardellichio CB, Coon HC (1986) Latent infection of KB cells with adeno-associated virus type 2. J Virol 60: 515-524.
-
(1986)
J Virol
, vol.60
, pp. 515-524
-
-
Laughlin, C.A.1
Cardellichio, C.B.2
Coon, H.C.3
-
61
-
-
0023889191
-
Adeno-associated virus general transduction vectors: Analysis of proviral structures
-
McLaughlin SK, Collis P, Hermonat PL, Muzyczka N (1988) Adeno-associated virus general transduction vectors: analysis of proviral structures. J Virol 62: 1963-1973.
-
(1988)
J Virol
, vol.62
, pp. 1963-1973
-
-
McLaughlin, S.K.1
Collis, P.2
Hermonat, P.L.3
Muzyczka, N.4
-
62
-
-
0034004021
-
Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates
-
Davis MD, Wu J, Owens RA (2000) Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates. J Virol 74: 2936-2942.
-
(2000)
J Virol
, vol.74
, pp. 2936-2942
-
-
Davis, M.D.1
Wu, J.2
Owens, R.A.3
-
63
-
-
0033052212
-
Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitro
-
Davis MD, Wonderling RS, Walker SL, Owens RA (1999) Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitro. J Virol 73: 2084-2093.
-
(1999)
J Virol
, vol.73
, pp. 2084-2093
-
-
Davis, M.D.1
Wonderling, R.S.2
Walker, S.L.3
Owens, R.A.4
-
64
-
-
0032826397
-
Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins
-
Wu J, Davis MD, Owens RA (1999) Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins. J Virol 73: 8235-8244.
-
(1999)
J Virol
, vol.73
, pp. 8235-8244
-
-
Wu, J.1
Davis, M.D.2
Owens, R.A.3
-
65
-
-
0030896669
-
Mutational analysis of the adeno-associated virus Rep68 protein: Identification of critical residues necessary for site-specific endonuclease activity
-
Walker SL, Wonderling RS, Owens RA (1997) Mutational analysis of the adeno-associated virus Rep68 protein: identification of critical residues necessary for site-specific endonuclease activity. J Virol 71: 2722-2730.
-
(1997)
J Virol
, vol.71
, pp. 2722-2730
-
-
Walker, S.L.1
Wonderling, R.S.2
Owens, R.A.3
-
66
-
-
0030846525
-
Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs
-
Walker SL, Wonderling RS, Owens RA (1997) Mutational analysis of the adeno-associated virus type 2 Rep68 protein helicase motifs. J Virol 71: 6996-7004.
-
(1997)
J Virol
, vol.71
, pp. 6996-7004
-
-
Walker, S.L.1
Wonderling, R.S.2
Owens, R.A.3
-
67
-
-
0028290387
-
Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein
-
McCarty DM, Pereira DJ, Zolotukhin I, Zhou X, Ryan JH, et al. (1994) Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein. J Virol 68: 4988-4997.
-
(1994)
J Virol
, vol.68
, pp. 4988-4997
-
-
McCarty, D.M.1
Pereira, D.J.2
Zolotukhin, I.3
Zhou, X.4
Ryan, J.H.5
-
68
-
-
0030026754
-
Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats
-
Ryan JH, Zolotukhin S, Muzyczka N (1996) Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats. J Virol 70: 1542-1553.
-
(1996)
J Virol
, vol.70
, pp. 1542-1553
-
-
Ryan, J.H.1
Zolotukhin, S.2
Muzyczka, N.3
-
69
-
-
0023947989
-
DNA amplification of adeno-associated virus as a response to cellular genotoxic stress
-
Yalkinoglu AO, Heilbronn R, Burkle A, Schlehofer JR, zur Hausen H (1988) DNA amplification of adeno-associated virus as a response to cellular genotoxic stress. Cancer Res 48: 3123-3129.
-
(1988)
Cancer Res
, vol.48
, pp. 3123-3129
-
-
Yalkinoglu, A.O.1
Heilbronn, R.2
Burkle, A.3
Schlehofer, J.R.4
Hausen, H.Z.5
-
70
-
-
0031965318
-
Role of the adenovirus DNA-binding protein in in vitro adeno-associated virus DNA replication
-
Ward P, Dean FB, O'Donnell ME, Berns KI (1998) Role of the adenovirus DNA-binding protein in in vitro adeno-associated virus DNA replication. J Virol 72: 420-427.
-
(1998)
J Virol
, vol.72
, pp. 420-427
-
-
Ward, P.1
Dean, F.B.2
O'Donnell, M.E.3
Berns, K.I.4
-
71
-
-
0034790801
-
Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system
-
Ward P, Falkenberg M, Elias P, Weitzman M, Linden RM (2001) Rep-dependent initiation of adeno-associated virus type 2 DNA replication by a herpes simplex virus type 1 replication complex in a reconstituted system. J Virol 75: 10250-10258.
-
(2001)
J Virol
, vol.75
, pp. 10250-10258
-
-
Ward, P.1
Falkenberg, M.2
Elias, P.3
Weitzman, M.4
Linden, R.M.5
-
72
-
-
0035194442
-
Involvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome
-
Zentilin L, Marcello A, Giacca M (2001) Involvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome. J Virol 75: 12279-12287.
-
(2001)
J Virol
, vol.75
, pp. 12279-12287
-
-
Zentilin, L.1
Marcello, A.2
Giacca, M.3
-
73
-
-
33646160992
-
The biology of Ku and its potential oncogenic role in cancer
-
Gullo C, Au M, Feng G, Teoh G (2006) The biology of Ku and its potential oncogenic role in cancer. Biochim Biophys Acta 1765: 223-234.
-
(2006)
Biochim Biophys Acta
, vol.1765
, pp. 223-234
-
-
Gullo, C.1
Au, M.2
Feng, G.3
Teoh, G.4
-
74
-
-
0032933430
-
The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit
-
Singleton BK, Torres-Arzayus MI, Rottinghaus ST, Taccioli GE, Jeggo PA (1999) The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit. Mol Cell Biol 19: 3267-3277.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3267-3277
-
-
Singleton, B.K.1
Torres-Arzayus, M.I.2
Rottinghaus, S.T.3
Taccioli, G.E.4
Jeggo, P.A.5
-
75
-
-
0043133778
-
Autopho-sphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
Ding Q, Reddy YV, Wang W, Woods T, Douglas P, et al. (2003) Autopho-sphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol Cell Biol 23: 5836-5848.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
Reddy, Y.V.2
Wang, W.3
Woods, T.4
Douglas, P.5
-
76
-
-
4043073590
-
Autopho-sphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends
-
Block WD, Yu Y, Merkle D, Gifford JL, Ding Q, et al. (2004) Autopho-sphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends. Nucleic Acids Res 32: 4351-4357.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 4351-4357
-
-
Block, W.D.1
Yu, Y.2
Merkle, D.3
Gifford, J.L.4
Ding, Q.5
-
77
-
-
0028116725
-
Human DNA helicase II: A novel DNA unwinding enzyme identified as the Ku autoantigen
-
Tuteja N, Tuteja R, Ochem A, Taneja P, Huang NW, et al. (1994) Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J 13: 4991-5001.
-
(1994)
EMBO J
, vol.13
, pp. 4991-5001
-
-
Tuteja, N.1
Tuteja, R.2
Ochem, A.3
Taneja, P.4
Huang, N.W.5
-
78
-
-
0037383480
-
Consequences of DNA-dependent protein kinase catalytic subunit deficiency on recombinant adeno-associated virus genome circularization and heterodimerization in muscle tissue
-
Duan D, Yue Y, Engelhardt JF (2003) Consequences of DNA-dependent protein kinase catalytic subunit deficiency on recombinant adeno-associated virus genome circularization and heterodimerization in muscle tissue. J Virol 77: 4751-4759.
-
(2003)
J Virol
, vol.77
, pp. 4751-4759
-
-
Duan, D.1
Yue, Y.2
Engelhardt, J.F.3
-
79
-
-
0035957384
-
Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle
-
Song S, Laipis PJ, Berns KI, Flotte TR (2001) Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle. Proc Natl Acad Sci U S A 98: 4084-4088.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 4084-4088
-
-
Song, S.1
Laipis, P.J.2
Berns, K.I.3
Flotte, T.R.4
-
80
-
-
33750357800
-
Host cell DNA repair pathways in adeno-associated viral genome processing
-
Choi VW, McCarty DM, Samulski RJ (2006) Host cell DNA repair pathways in adeno-associated viral genome processing. J Virol 80: 10346-10356.
-
(2006)
J Virol
, vol.80
, pp. 10346-10356
-
-
Choi, V.W.1
McCarty, D.M.2
Samulski, R.J.3
-
81
-
-
35148863458
-
The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice
-
Inagaki K, Ma C, Storm TA, Kay MA, Nakai H (2007) The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice. J Virol 81: 11304-11321.
-
(2007)
J Virol
, vol.81
, pp. 11304-11321
-
-
Inagaki, K.1
Ma, C.2
Storm, T.A.3
Kay, M.A.4
Nakai, H.5
-
82
-
-
0037130170
-
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
-
Stracker TH, Carson CT, Weitzman MD (2002) Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418: 348-352.
-
(2002)
Nature
, vol.418
, pp. 348-352
-
-
Stracker, T.H.1
Carson, C.T.2
Weitzman, M.D.3
-
83
-
-
36348963101
-
The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication
-
Schwartz RA, Palacios JA, Cassell GD, Adam S, Giacca M, et al. (2007) The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. J Virol 81: 12936-12945.
-
(2007)
J Virol
, vol.81
, pp. 12936-12945
-
-
Schwartz, R.A.1
Palacios, J.A.2
Cassell, G.D.3
Adam, S.4
Giacca, M.5
-
84
-
-
0347157844
-
Mcm4,6,7 uses a ''pump in ring'' mechanism to unwind DNA by steric exclusion and actively translocate along a duplex
-
Kaplan DL, Davey MJ, O'Donnell M (2003) Mcm4,6,7 uses a ''pump in ring'' mechanism to unwind DNA by steric exclusion and actively translocate along a duplex. J Biol Chem 278: 49171-49182.
-
(2003)
J Biol Chem
, vol.278
, pp. 49171-49182
-
-
Kaplan, D.L.1
Davey, M.J.2
O'Donnell, M.3
-
85
-
-
0032954382
-
Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities
-
Zhou X, Zolotukhin I, Im DS, Muzyczka N (1999) Biochemical characterization of adeno-associated virus rep68 DNA helicase and ATPase activities. J Virol 73: 1580-1590.
-
(1999)
J Virol
, vol.73
, pp. 1580-1590
-
-
Zhou, X.1
Zolotukhin, I.2
Im, D.S.3
Muzyczka, N.4
-
86
-
-
0029995531
-
A ''humanized'' green fluorescent protein cDNA adapted for high-level expression in mammalian cells
-
Zolotukhin S, Potter M, Hauswirth WW, Guy J, Muzyczka N (1996) A ''humanized'' green fluorescent protein cDNA adapted for high-level expression in mammalian cells. J Virol 70: 4646-4654.
-
(1996)
J Virol
, vol.70
, pp. 4646-4654
-
-
Zolotukhin, S.1
Potter, M.2
Hauswirth, W.W.3
Guy, J.4
Muzyczka, N.5
-
87
-
-
0037112508
-
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation
-
Peng Y, Zhang Q, Nagasawa H, Okayasu R, Liber HL, et al. (2002) Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation. Cancer Res 62: 6400-6404.
-
(2002)
Cancer Res
, vol.62
, pp. 6400-6404
-
-
Peng, Y.1
Zhang, Q.2
Nagasawa, H.3
Okayasu, R.4
Liber, H.L.5
|