Herpes simplex virus type 1 immediate-early protein Vmw110 induces the proteasome-dependent degradation of the catalytic subunit of DNA-dependent protein kinase

Journal of Virology

Volumn 73, Issue 1, 1999, Pages 650-657

  Parkinson, Jane ^a   Lees Miller, Susan P ^b   Everett, Roger D ^a  

^a INSTITUTE OF VIROLOGY   (United Kingdom)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE; IMMEDIATE EARLY PROTEIN; PROTEASOME; PROTEIN KINASE; VIRUS PROTEIN;

ARTICLE; DNA DEGRADATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE EXPRESSION REGULATION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; VIRUS GENOME;

EID: 0032889431     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.1.650-657.1999     Document Type: Article

References (28)

1. Ascoli, C. A., and G. G. Maul. 1991. Identification of a novel nuclear domain. J. Cell Biol. 112:785-795.
2. Boddy, M. N., K. Howe, L. D. Etkin, E. Solomon, and P. S. Freemont. 1996. PIC1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia. Oncogene 13:971-982.
3. Cai, W., T. D. Astor, L. M. Liptak, C. Cho, D. Coen, and P. A. Schaffer. 1993. The herpes simplex virus type 1 regulatory protein ICP0 enhances replication during acute infection and reactivation from latency. J. Virol. 67:7501-7512.
4. Chan, D. W., and S. P. Lees-Miller. 1996. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J. Biol. Chem. 271:8936-8941.
5. Chibazakura, T., F. Watanabe, S. Kitajima, K. Tsukada, Y. Yasukochi, and H. Teraoka. 1997. Phosphorylation of human general transcription factors TATA-binding protein and transcription factor IIB by DNA-dependent protein kinase - synergistic stimulation of RNA polymerase II basal transcription in vitro. Eur. J. Biochem. 247:1166-1173.
6. Clements, G. B., and N. D. Stow. 1989. A herpes simplex virus type 1 mutant containing a deletion within immediate-early gene 1 is latency competent in mice. J. Virol. 70:2501-2506.
7. Cross, A., and R. Everett. Unpublished data.
8. Dick, L. R., A. A. Cruikshank, A. T. Destree, L. Grenier, T. A. McCormack, F. D. Melandri, S. L. Nunes, V. J. Palombella, L. A. Parent, L. Plamondon, and R. L. Stein. 1997. Mechanistic studies on inactivation of the proteasome by lactacystin in cultured cells. J. Biol. Chem. 272:182-188.
9. 7a.Dyck, J. A., G. G. Maul, W. H. Miller, Jr., J. D. Chen, A. Kakizuka, and R. M. Evans. 1994. A novel macromolecular structure is a target of the promyelocytic-retinoic acid receptor oncoprotein. Cell 76:333-343.
10. Dynan, W. D., and S. Yoo. 1998. Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res. 26:1551-1559.
11. Everett, R. D. 1989. Construction and characterisation of herpes simplex virus type 1 mutants with defined lesions in immediate-early gene 1. J. Gen. Virol. 70:1185-1202.
12. Everett, R. D., C. M. Preston, and N. D. Stow. 1991. Functional and genetic analysis of the role of Vmw110 in herpes simplex virus replication, p. 50-76. In E. K. Wagner (ed.), The control of herpes simplex virus gene expression. CRC Press, Inc., Boca Raton, Fla.
13. Everett, R. D., A. Cross, J. K. Tyler, and A. Orr. 1993. An epitope within the DNA binding domain of the herpes simplex virus immediate-early protein Vmw175 is conserved in the varicella-zoster virus gene 62 protein. J. Gen. Virol. 74:1955-1958.
14. Everett, R. D., A. Cross, and A. Orr. 1993. A truncated form of herpes simplex virus type 1 immediate-early protein Vmw110 is expressed in a cell-type dependent manner. Virology 197:751-756.
15. Everett, R. D., and G. G. Maul. 1994. HSV-1 IE protein Vmw110 causes redistribution of PML. EMBO J. 13:5062-5069.
16. Everett, R. D., M. R. Meredith, A. Orr, A. Cross, M. Kathoria, and J. Parkinson. 1997. A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein. EMBO J. 16:1519-1530.
17. Everett, R. D., P. Freemont, H. Saitoh, M. Dasso, A. Orr, M. Kathoria, and J. Parkinson. 1998. The disruption of the ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms. J. Virol. 72:6581-6591.
18. Everett, R. D., M. Meredith, and A. Orr. 1999. The ability of herpes simplex virus type 1 immediate-early protein Vmw110 to bind to a ubiquitin-specific protease contributes to its role in the activation of gene expression and stimulation of virus replication. J. Virol. 73:417-426
19. Fraser, N. W., T. M. Block, and J. G. Spivack. 1992. The latency associated transcripts of herpes simplex virus: RNA in search of a function. Virology 191:1-8.
20. Giffin, W., H. Torrence, D. J. Rodda, G. G. Prefontaine, L. Pope, and R. J. G. Hache. 1996. Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature (London) 380:265-268.
21. Harris, R. A., R. D. Everett, X. Zhu, S. Silverstein, and C. M. Preston. 1989. The HSV immediate early protein Vmw110 reactivates latent HSV type 2 in an in vitro latency system. J. Virol. 63:3513-3515.
22. Hochstrasser, M. 1995. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol. 7:215-223.
23. Johnson, P. R., and M. Hochstrasser. 1997. SUMO-1: ubiquitin gains weight. Trends Cell Biol. 7:408-413.
24. Jordan, R., and P. A. Schaffer. 1997. Activation of gene expression by herpes simplex virus type 1 ICP0 occurs at the level of mRNA synthesis. J. Virol. 71:6850-6862.
25. Kamitani, T., H. P. Nguyen, and E. T. H. Yeh. 1997. Preferential modification of nuclear proteins by a novel ubiquitin-like molecule. J. Biol. Chem. 272:14001-14004.
26. Kamitani, T., H. P. Ngujen, K. Kito, T. FuKuda-Kamitani, and E. T. H. Yeh. 1998. Covalent modification of PML by the Sentrin family of ubiquitin-like proteins. J. Biol. Chem. 273:3117-3120.
27. Kawaguchi, Y., C. van Sant, and B. Roizman. 1997. Herpes simplex virus regulatory protein ICP0 interacts with and stabilizes the cell cycle regulator cyclin D3. J. Virol. 71:7328-7336.
28. Korioth, F., C. Gieffers, G. G. Maul, and J. Frey. 1995. Molecular characterisation of NDP52, a novel protein of nuclear domain 10 which is redistributed upon infection and interferon treatment. J. Cell Biol. 130:1-14.