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Volumn 3, Issue 1, 2012, Pages 90-101

Amidines bearing benzofuroxan or benzimidazole 1,3-dioxide core scaffolds as Trypanosoma cruzi-inhibitors: Structural basis for their interactions with cruzipain

(7) Merlino, Alicia a Benitez, Diego a Campillo, Nuria E b Páez, Juan A b Tinoco, Luzineide W c González, Mercedes a Cerecetto, Hugo a

a UNIVERSIDAD DE LA REPÚBLICA (Uruguay)

b INSTITUTO DE QUÍMICA MÉDICA (Spain)

c FEDERAL UNIVERSITY OF RIO DE JANEIRO (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2,2 DIMETHYL 5 [4 (N PHENYL N' PHENYLETHYL)AMIDINOPIPERAZIN 1 YLMETHYL] 2H BENZIMIDAZOLE 1,3 DI N OXIDE; 5 [4 (N BENZYL N' PHENYL)AMIDINOPIPERAZIN 1 YLMETHYL] 2,2 DIMETHYL 2H BENZIMIDAZOLE 1,3 DI N OXIDE; 5 [4 (N BENZYL N' PHENYL)AMIDINOPIPERAZIN 1 YLMETHYL]BENZO[1,2 C]1,2,5 OXADIAZOLE N OXIDE; 5 [4 (N FURYL N' PHENYL)AMIDINOPIPERAZIN 1 YLMETHYL] 2,2 DIMETHYL 2H BENZIMIDAZOLE 1,3 DI N OXIDE; 5 [4 (N FURYL N' PHENYL)AMIDINOPIPERAZIN 1 YLMETHYL]BENZO[1,2 C]1,2,5 OXADIAZOLE N OXIDE; 5 [4 (N PHENYL N' PHENYLETHYL)AMIDINOPIPERAZIN 1 YLMETHYL]BENZO[1,2 C]1,2,5 OXADIAZOLE N OXIDE; 5 [4 (N,N' DIPHENYL)AMIDINOPIPERAZIN 1 YLMETHYL]BENZO[1,2 C]1,2,5 OXADIAZOLE N OXIDE; AMIDINE; ANTITRYPANOSOMAL AGENT; AROMATIC COMPOUND; BENZIMIDAZOLE 1,3 DIOXIDE; BENZIMIDAZOLE DERIVATIVE; BENZOFUROXAN; CRUZIPAIN; CRUZIPAIN INHIBITOR; CYSTEINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MOLECULAR DOCKING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTON TRANSPORT; SPECTROSCOPY; STATIC ELECTRICITY; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 84855704061 PISSN: 20402503 EISSN: 20402511 Source Type: Journal
DOI: 10.1039/c1md00223f Document Type: Conference Paper

Times cited : (17)

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