Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents

Journal of Inorganic Biochemistry

Volumn 102, Issue 5-6, 2008, Pages 1033-1043

  Vieites, Marisol ^a   Otero, Lucía ^a   Santos, Diego ^a   Toloza, Jeannette ^b   Figueroa, Roberto ^b   Norambuena, Ester ^c   Olea Azar, Claudio ^b   Aguirre, Gabriela ^a   Cerecetto, Hugo ^a   González, Mercedes ^a   Morello, Antonio ^d   Maya, Juan Diego ^d   Garat, Beatriz ^e   Gambino, Dinorah ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSIDAD METROPOLITANA DE CIENCIAS DE LA EDUCACIÓN   (Chile)

^d UNIVERSITY OF CHILE   (Chile)

^e UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

5 Nitrofuryl containing thiosemicarbazones; Chagas' disease; Free radical production; N,S ligands; Platinum

Indexed keywords

4 ETHYL 1 (5 NITROFURFURYLIDINE)THIOSEMICARBAZIDE; 5 NITROFURYL; ANTIPROTOZOAL AGENT; DNA; FREE RADICAL; METAL COMPLEX; NIFURTIMOX; OXYGEN; PLATINUM; THIOSEMICARBAZIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DNA METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; IC 50; IN VITRO STUDY; NONHUMAN; OXYGEN CONSUMPTION; PROTEIN INTERACTION; TRYPANOSOMA CRUZI;

ANIMALS; DNA; FREE RADICALS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; ORGANOPLATINUM COMPOUNDS; SPECTROPHOTOMETRY, INFRARED; SPECTRUM ANALYSIS, RAMAN; THIOSEMICARBAZONES; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

TRYPANOSOMA CRUZI;

EID: 41949114635     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2007.12.005     Document Type: Article

References (42)

1. http://www.who.int/; .
2. Engels D., and Savioli L. Trend Parasitol. 22 (2006) 363-366
3. Urbina J. Expert Opin. Ther. Pat. 13 (2003) 661-669
4. Cerecetto H., and González M. Curr. Topics Med. Chem. 2 (2002) 1185-1190
5. Krauth-Siegel R.L., Bauer H., and Schirmer R.H. Angew. Chem. Int. Ed. 44 (2005) 690-715
6. Croft S., Barret M., and Urbina J. Trend Parasitol. 21 (2005) 508-512
7. Ceaser M. The Lancet Infect. Dis. 5 8 (2005) 470-471
8. Yamagata Y., and Nakagawa J. Adv. Parasitol. 61 (2006) 129-165
9. Zhang C., and Lippard S. Curr. Opin. Chem. Biol. 7 (2003) 481-489
10. Farrell N.P. Metal Complexes as Drugs and Chemotherapeutic Agents. In: McCleverty J.M., and Meyer T.J. (Eds). Comprehensive Coordination Chemistry II vol. 9 (2003), Elsevier 809-840
11. Sánchez-Delgado R.A., Anzellotti A., and Suárez L. Metal complexes as chemotherapeutic agents against tropical diseases: malaria, trypanosomiasis, and leishmaniasis. In: Sigel H., and Sigel A. (Eds). Metal Ions in Biological Systems vol. 41 (2004), Marcel Dekker, New York 379-419
12. Sánchez-Delgado R.A., and Anzellotti A. Mini-Rev. Med. Chem. 4 (2004) 23-30
13. Morphy R., and Rankovic Z. J. Med. Chem. 48 (2005) 6523-6543
14. Wang Z., Bennett E.M., Wilson D.J., Salomon C., and Vince R. J. Med. Chem. 50 (2007) 3416-3419
15. K. Chibale, Towards broad spectrum antiprotozoal agents. ARKIVOC IX, 2002, pp. 93-98.
16. Urquiola C., Vieites M., Aguirre G., Marín A., Solano B., Arrambide G., Lavaggi M.L., Torre M.H., González M., Monge A., Gambino D., and Cerecetto H. Bioorg. Med. Chem. 14 (2006) 5503-5509
17. Aguirre G., Cerecetto H., González M., Gambino D., Otero L., Olea-Azar C., Rigol C., and Denicola A. Bioorg. Med. Chem. 12 (2004) 4885-4893
18. Otero L., Vieites M., Boiani L., Denicola A., Rigol C., Opazo L., Olea-Azar C., Maya J.D., Morello A., Krauth-Siegel R.L., Piro O.E., Castellano E., González M., Gambino D., and Cerecetto H. J. Med. Chem. 49 (2006) 3322-3331
19. Gómez-Quiroga A., and Navarro-Ranninger C. Coord. Chem. Rev. 248 (2004) 119-133
20. Hall M.D., and Hambley T.W. Coord. Chem. Rev. 232 (2002) 49-67
21. Hambley T.W. Coord. Chem. Rev. 166 (1997) 181-223
22. Bonse S., Richards J.M., Ross S.A., Lowe G., and Krauth-Siegel R.L. J. Med. Chem. 43 (2000) 4812-4821
23. Lowe G., Droz A.S., Vilaiyan T., Weaver G.W., Tweedale L., Pratt J.M., Rock P., Yardley V., and Croft S.L. J. Med. Chem. 42 (1999) 999-1006
24. Croft S.L. Mem. Inst. Oswaldo Cruz 94 (1999) 215-220
25. Geary W.J. Coord. Chem. Rev. 7 (1971) 81-91
26. Rigol C., Olea-Azar C., Mendizábal F., Otero L., Gambino D., González M., and Cerecetto H. Spectrochim. Acta A 61 (2005) 2933-2938
27. Huang L., Lee A., and Ellman J.A. J. Med. Chem. 45 (2002) 676-684
28. Maya J.D., Morello A., Repetto Y., Tellez R., Rodriguez A., Zelada U., Puebla P., Bontá M., Bollo S., and San Feliciano A. Comp. Biochem. Phys. C 125 (2000) 103-109
29. Cuellar M.A., Salas C., Cortés M.J., Morello A., Maya J.D., and Preitea M.D. Bioorg. Med. Chem. 11 (2003) 2489-2497
30. Mahnken R.E., Billadeau M.A., Nikonowicz E.P., and Morrison H. J. Am. Chem. Soc. 114 (1992) 9253-9265
31. Letelier M.E., Rodríguez E., Wallace A., Lorca M., Repetto Y., Morello A., and Aldunate J. Exp. Parasitol. 71 (1990) 357-363
32. Gambino D., Otero L., Vieites M., Boiani M., González M., Baran E.J., and Cerecetto H. Spectrochim. Acta A 68 (2007) 341-348
33. L. Otero, C. Folch, G. Barriga, C. Rigol, L. Opazo, M. Vieites, D. Gambino, H. Cerecetto, E. Norambuena,C. Olea-Azar, Spectrochim. Acta A, .
34. Olea-Azar C., Rigol C., Mendizábal F., Morello A., Maya J.D., Moncada C., Cabrera E., Di Maio R., Gonzalez M., and Cerecetto H. Free Rad. Res. 37 (2003) 993-1001
35. Bollo S., Soto-Bustamante E., Núñez-Vergara L.J., and Squella J.A. J. Electroanal. Chem. 492 (2000) 54-62
36. Olea-Azar C., Atria A.M., Mendizábal F., Di Maio R., Seoane G., and Cerecetto H. Spectrosc. Lett. 31 (1998) 99-109
37. Arán V.J., Ochoa C., Boiani L., Buccino P., Cerecetto H., Gerpe A., González M., Montero D., Nogal J.J., Gómez-Barrio A., Azqueta A., López de Ceraín A., Piro O.E., and Castellano E.E. Bioorg. Med. Chem. 13 (2005) 3197-3207
38. Tyler K.M., and Engman D.M. Int. J. Parasitol. 31 (2001) 472-480
39. Repetto Y., Opazo E., Maya J.D., Agosin M., and Morello A. Comp. Biochem. Phys. B 115 (1996) 281-285
40. Veerapen N., Taylor S.A., Walsby C.J., and Mario Pinto B. J. Am. Chem. Soc. 128 (2006) 227-239
41. Maya J.D., Bollo S., Nuñez-Vergara L.J., Squella J.A., Repetto Y., Morello A., Périé J., and Chauvière G. Biochem. Pharmacol. 65 (2003) 999-1006
42. Brabec V. Prog. Nucl. Acid Res. Mol. Biol. 71 (2002) 1-68