In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles

European Journal of Medicinal Chemistry

Volumn 44, Issue 3, 2009, Pages 1034-1040

  Boiani, Lucia ^a   Gerpe, Alejandra ^a   Arán, Vicente J ^b   Torres de Ortiz, Susana ^c   Serna, Elva ^c   Vera de Bilbao, Ninfa ^c   Sanabria, Luis ^c   Yaluff, Gloria ^c   Nakayama, Héctor ^c   Rojas de Arias, Antonieta ^c   Maya, Juan Diego ^d   Morello, J Antonio ^d   Cerecetto, Hugo ^a   González, Mercedes ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^c Instituto de Investigaciones en Ciencias de la Salud Universidad Nacional de Asuncion   (Paraguay)

^d UNIVERSITY OF CHILE   (Chile)

Author keywords

Chagas' disease; Leishmaniasis; Nitroindazoles; Therapy

Indexed keywords

5 NITROINDAZOLE DERIVATIVE; ANTIPROTOZOAL AGENT; BENZNIDAZOLE; CRYSTAL VIOLET; INDAZOLE DERIVATIVE; PENTAMIDINE ISETHIONATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; DRUG STRUCTURE; EPIMASTIGOTE; IN VITRO STUDY; IN VIVO STUDY; LEISHMANIA; LEISHMANIA BRAZILIENSIS; LEISHMANIA INFANTUM; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PROMASTIGOTE; TREATMENT OUTCOME; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ANIMALS; DRUG EVALUATION, PRECLINICAL; INDAZOLES; LEISHMANIA; MICE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 60849094374     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.06.024     Document Type: Article

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