Naftifine-analogues as anti-Trypanosoma cruzi agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2010, Pages 2154-2164

  Gerpe, Alejandra ^a   Boiani, Lucía ^a   Hernández, Paola ^a   Sortino, Maximiliano ^b   Zacchino, Susana ^b   González, Mercedes ^a   Cerecetto, Hugo ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

Alkenylamine; Anti T. cruzi agents; Benzimidazole 1,3 dioxide; Benzofuroxan; Indazole N oxide; Quinoxaline 1,4 dioxide

Indexed keywords

2,2 DIMETHYL 5 [(N METHYL 3 PHENYL 2 PROPENYLAMINO)METHYL] 2H BENZIMIDAZOLE 1,3 DIOXIDE; 2,2 DIMETHYL 5 [4 (3 PHENYL 2 PROPENYL)PIPERAZINE 1 YL METHYL]; 4 ALLYL 1 (2 ETHOXYCARBONYL 1,4 DIOXIDE 3 PHENYLQUINOXALINE 7 YL)METHYLIDENE THIOSEMICARBAZIDE; 4 ALLYL 1 (2,2 DIMETHYL 1,3 DIOXIDE 2H BENZIMIDAZOLE 5 YL)METHYLIDENETHIOSEMICARBAZIDE; ANTITRYPANOSOMAL AGENT; NAFTIFINE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; MICROANALYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; STEROL SYNTHESIS; THIN LAYER CHROMATOGRAPHY; TRYPANOSOMA CRUZI;

ALLYLAMINE; ANIMALS; CELL LINE; DRUG DESIGN; FUNGI; INHIBITORY CONCENTRATION 50; MICE; MICROBIAL SENSITIVITY TESTS; SQUALENE; TRYPANOCIDAL AGENTS; TRYPANOSOMA CRUZI;

EID: 77950867840     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.01.052     Document Type: Article

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