-
1
-
-
80052787583
-
Alpha-1-adrenergic receptors: Targets for agonist drugs to treat heart failure
-
Jensen BC, O'Connell TD, Simpson PC. Alpha-1-adrenergic receptors: Targets for agonist drugs to treat heart failure. J MolCell Cardiol 2011;51:518-28
-
(2011)
J. Mol. Cell Cardiol.
, vol.51
, pp. 518-528
-
-
Jensen, B.C.1
O'Connell, T.D.2
Simpson, P.C.3
-
2
-
-
78649662125
-
The alpha1-adrenergic receptors: Diversity of signaling networks and regulation
-
Cotecchia S. The alpha1-adrenergic receptors: Diversity of signaling networks and regulation. J Recept Signal Transduct Res 2010;15:410-19
-
(2010)
J. Recept. Signal Transduct Res.
, vol.15
, pp. 410-419
-
-
Cotecchia, S.1
-
3
-
-
0029117219
-
Identification of critical determinants of alpha1-adrenergic receptor subtype selective agonist binding
-
Hwa J, Graham RM, Perez DM. Identification of critical determinants of alpha1-adrenergic receptor subtype selective agonist binding. J. Biol. Chem. 1995;270:23189-95
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23189-23195
-
-
Hwa, J.1
Graham, R.M.2
Perez, D.M.3
-
5
-
-
0025102753
-
Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells fos/jun expression is associated with sarcomere assembly; egr-1 induction is primarily an alpha1-mediated response
-
Iwaki K, Sukhatme VP, Shubeita HE, Chien KR. alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. Fos/jun expression is associated with sarcomere assembly; egr-1 induction is primarily an alpha1-mediated response. J. Biol. Chem. 1990;265:13809-17
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 13809-13817
-
-
Iwaki, K.1
Sukhatme, V.P.2
Shubeita, H.E.3
Chien, K.R.4
-
6
-
-
0027176441
-
The α(1A)-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
-
Knowlton KU, Michel MC, Itani M, et al. The alpha1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. J. Biol. Chem. 1993;268:15374-80 (Pubitemid 23222024)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.21
, pp. 15374-15380
-
-
Knowlton, K.U.1
Michel, M.C.2
Itani, M.3
Shubeita, H.E.4
Ishihara, K.5
Brown, J.H.6
Chien, K.R.7
-
7
-
-
0034452038
-
1-adrenergic receptor regulation: Basic science and clinical implications
-
DOI 10.1016/S0163-7258(00)00092-9, PII S0163725800000929
-
Michelotti GA, Price DT, Schwinn DA. alpha1-adrenergic receptor regulation: Basic science and clinical implications. Pharmacol. Ther. 2000;88:281-309 (Pubitemid 32406055)
-
(2000)
Pharmacology and Therapeutics
, vol.88
, Issue.3
, pp. 281-309
-
-
Michelotti, G.A.1
Price, D.T.2
Schwinn, D.A.3
-
8
-
-
0030921287
-
1-adrenergic receptor and Ras activation and is associated with in vitro and in vivo cardiac hypertrophy
-
DOI 10.1074/jbc.272.22.14057
-
Ramirez MT, Sah VP, Zhao XL., et al. The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy. J. Biol. Chem. 1997;272:14057-61 (Pubitemid 27232807)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.22
, pp. 14057-14061
-
-
Ramirez, M.T.1
Sah, V.P.2
Zhao, X.-L.3
Hunter, J.J.4
Chien, K.R.5
Brown, J.H.6
-
9
-
-
0030807080
-
1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes: Evidence for involvement of p70 S6 kinase
-
Boluyt MO, Zheng JS, Younes A, et al. Rapamycin inhibits alpha1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70 s6 kinase. Circ Res 1997;81:176-86 (Pubitemid 27342484)
-
(1997)
Circulation Research
, vol.81
, Issue.2
, pp. 176-186
-
-
Boluyt, M.O.1
Zheng, J.-S.2
Younes, A.3
Long, X.4
O'Neill, L.5
Silverman, H.6
Lakatta, E.G.7
Crow, M.T.8
-
10
-
-
0032872522
-
Stimulation by transforming growth factor-α of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: Modulation by α- and β-adrenoceptor agonists
-
Kimura M, Ogihara M. Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: Modulation by alpha- and beta-adrenoceptor agonists. J Pharmacol Exp Ther 1999;291:171-80 (Pubitemid 29451587)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.291
, Issue.1
, pp. 171-180
-
-
Kimura, M.1
Ogihara, M.2
-
11
-
-
0033544914
-
1BAR inhibits IL-6-activated stat3 in hepatic cells by a p42/44 mitogen-activated protein kinase-dependent mechanism
-
Nguyen VA, Gao B. Cross-talk between alpha1B-adrenergic receptor (alpha1BAR) and interleukin-6 (IL-6) signaling pathways. Activation of alpha1BAR inhibits il-6-activated STAT3 in hepatic cells by a p42/44 mitogen-activated protein kinase-dependent mechanism. J. Biol. Chem. 1999;274:35492-8 (Pubitemid 129512842)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.50
, pp. 35492-35498
-
-
Nguyen, V.-A.T.1
Gao, B.2
-
12
-
-
0032491596
-
Phosphorylation of the cAMP response element-binding protein and activation of transcription by adrenergic receptors
-
DOI 10.1074/jbc.273.45.30033
-
Lin RZ, Chen J, Hu ZW, Hoffman BB. Phosphorylation of the cAMP response element-binding protein and activation of transcription by alpha1 adrenergic receptors. J. Biol. Chem. 1998;273:30033-8 (Pubitemid 28510022)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.45
, pp. 30033-30038
-
-
Lin, R.Z.1
Chen, J.2
Hu, Z.-W.3
Hoffman, B.B.4
-
13
-
-
0034581716
-
The autonomic and sensory innervation of the smooth muscle of the prostate gland: A review of pharmacological and histological studies
-
DOI 10.1046/j.1365-2680.2000.00195.x
-
Pennefather JN, Lau WA, Mitchelson F, Ventura S. The autonomic and sensory innervation of the smooth muscle of the prostate gland: A review of pharmacological and histological studies. J Auton Pharmacol 2000;20:193-206 (Pubitemid 34211031)
-
(2000)
Journal of Autonomic Pharmacology
, vol.20
, Issue.4
, pp. 193-206
-
-
Pennefather, J.N.1
Lau, W.A.K.2
Mitchelson, F.3
Ventura, S.4
-
14
-
-
0037955958
-
2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells
-
DOI 10.1113/jphysiol.2002.036772
-
2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells. J Physiol 2003;548:823-36 (Pubitemid 36603302)
-
(2003)
Journal of Physiology
, vol.548
, Issue.3
, pp. 823-836
-
-
Sydorenko, V.1
Shuba, Y.2
Thebault, S.3
Roudbaraki, M.4
Lepage, G.5
Prevarskaya, N.6
Skryma, R.7
-
16
-
-
33847033761
-
Dominance of the alpha1B-adrenergic receptor and its subcellular localization in human and tramp prostate cancer cell lines
-
Shi T, Gaivin RJ, McCune DF, et al. Dominance of the alpha1B-adrenergic receptor and its subcellular localization in human and tramp prostate cancer cell lines. J Recept Signal Transduct Res 2007;27-27-45
-
(2007)
J. Recept Signal Transduct Res.
, vol.27
, pp. 27-45
-
-
Shi, T.1
Gaivin, R.J.2
McCune, D.F.3
-
17
-
-
79953223742
-
Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1alpha protein-dependent mechanism
-
Park SY, Kang JH, Jeong KJ, et al. Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1alpha protein-dependent mechanism. Int J Cancer 2011;128:2306-16
-
(2011)
Int. J. Cancer
, vol.128
, pp. 2306-2316
-
-
Park, S.Y.1
Kang, J.H.2
Jeong, K.J.3
-
18
-
-
0033071021
-
Localization and expression of the alpha1A alpha1B and alpha1D-adrenoceptors in hyperplastic and non-hyperplastic human prostate
-
Walden PD, Gerardi C, Lepor H. Localization and expression of the alpha1A, alpha1B and alpha1D-adrenoceptors in hyperplastic and non-hyperplastic human prostate. J Urol 1999;161:635-40
-
(1999)
J. Urol.
, vol.161
, pp. 635-640
-
-
Walden, P.D.1
Gerardi, C.2
Lepor, H.3
-
19
-
-
53749101119
-
Current role of alpha-blockers in the treatment of benign prostatic hyperplasia
-
Kaplan SA. Current role of alpha-blockers in the treatment of benign prostatic hyperplasia. BJU Int 2008;102(Suppl 2):3-7
-
(2008)
BJU Int.
, vol.102
, Issue.2
, pp. 3-7
-
-
Kaplan, S.A.1
-
20
-
-
12144265607
-
Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds
-
DOI 10.1021/jm049153d
-
Antonello A, Hrelia P, Leonardi A, et al. Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds. J Med Chem 2005;48:28-31 (Pubitemid 40105246)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.1
, pp. 28-31
-
-
Antonello, A.1
Hrelia, P.2
Leonardi, A.3
Marucci, G.4
Rosini, M.5
Tarozzi, A.6
Tumiatti, V.7
Melchiorre, C.8
-
21
-
-
0028985748
-
The epidemiology of benign prostatic hyperplasia and observations on concomitant hypertension
-
Boyle P, Napalkov P. The epidemiology of benign prostatic hyperplasia and observations on concomitant hypertension. Scand J Urol Nephrol Suppl 1995;168:7-12
-
(1995)
Scand. J. Urol. Nephrol. Suppl.
, vol.168
, pp. 7-12
-
-
Boyle, P.1
Napalkov, P.2
-
22
-
-
0014881495
-
Prazosin hydrochloride cp- 12 299- 1 an oral anti-hypertensive agent: Preliminary clinical observations in ambulatory patients
-
Cohen BM. Prazosin hydrochloride (cp- 12,299-1), an oral anti-hypertensive agent: Preliminary clinical observations in ambulatory patients. J Clin Pharmacol J New Drugs 1970;10:408-17
-
(1970)
J. Clin. Pharmacol. J. New Drugs
, Issue.10
, pp. 408-417
-
-
Cohen, B.M.1
-
23
-
-
0017572269
-
Prazosin: A review of its pharmacological properties and therapeutic efficacy in hypertension
-
Brogden RN, Heel RC, Speight TM, Avery GS. Prazosin: A review of its pharmacological properties and therapeutic efficacy in hypertension. Drugs 1977;14:163-97 (Pubitemid 8319383)
-
(1977)
Drugs
, vol.14
, Issue.3
, pp. 163-197
-
-
Brogden, R.N.1
Heel, R.C.2
Speight, T.M.3
Avery, G.S.4
-
25
-
-
0024313367
-
Clinical pharmacotherapeutics of doxazosin
-
Taylor SH. Clinical pharmacotherapeutics of doxazosin. Am. J. Med 1989;87:2S-11S (Pubitemid 19208767)
-
(1989)
American Journal of Medicine
, vol.87
, Issue.2 A
-
-
Taylor, S.H.1
-
26
-
-
0024312243
-
1-adrenergic inhibitor, on lipoproteins in patients with essential hypertension
-
Pool JL, Taylor AA, Nelson EB. Review of the effects of doxazosin, a new selective alpha 1-adrenergic inhibitor, on lipoproteins in patients with essential hypertension. Am. J. Med 1989;87:57S-61S (Pubitemid 19208775)
-
(1989)
American Journal of Medicine
, vol.87
, Issue.2 A
-
-
Pool, J.L.1
Taylor, A.A.2
Nelson, E.B.3
-
27
-
-
0028869716
-
Doxazosin an update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia
-
Fulton B, Wagstaff AJ, Sorkin EM. Doxazosin. An update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia. Drugs 1995;49:295-320
-
(1995)
Drugs
, vol.49
, pp. 295-320
-
-
Fulton, B.1
Wagstaff, A.J.2
Sorkin, E.M.3
-
28
-
-
0027603691
-
Terazosin a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in benign prostatic hyperplasia
-
Wilde MI, Fitton A, Sorkin EM. Terazosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. Drugs Aging 1993;3:258-77
-
(1993)
Drugs Aging
, vol.3
, pp. 258-277
-
-
Wilde, M.I.1
Fitton, A.2
Sorkin, E.M.3
-
29
-
-
0027477729
-
Alfuzosin: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia
-
Wilde MI, Fitton A, McTavish D. Alfuzosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in benign prostatic hyperplasia. Drugs 1993;45:410-29 (Pubitemid 23104126)
-
(1993)
Drugs
, vol.45
, Issue.3
, pp. 410-429
-
-
Wilde, M.I.1
Fitton, A.2
Mctavish, D.3
-
30
-
-
0036210668
-
Alfuzosin: A review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia
-
McKeage K, Plosker GL. Alfuzosin: A review of the therapeutic use of the prolonged-release formulation given once daily in the management of benign prostatic hyperplasia. Drugs 2002;62:633-53 (Pubitemid 34264032)
-
(2002)
Drugs
, vol.62
, Issue.4
, pp. 633-653
-
-
McKeage, K.1
Plosker, G.L.2
-
31
-
-
40149110208
-
1-blockers in chronic prostatitis syndromes
-
DOI 10.1111/j.1464-410X.2008.07496.x
-
Nickel JC. Role of alpha1-blockers in chronic prostatitis syndromes. BJU Int 2008;101(Suppl 3):11-16 (Pubitemid 351328801)
-
(2008)
BJU International, Supplement
, vol.101
, Issue.SUPPL. 3
, pp. 11-16
-
-
Nickel, J.C.1
-
32
-
-
0032426688
-
Induction of prostate apoptosis by doxazosin in benign prostatic hyperplasia
-
Kyprianou N, Litvak JP, Borkowski A, et al. Induction of prostate apoptosis by doxazosin in benign prostatic hyperplasia. J Urol 1998;159:1810-15 (Pubitemid 29190702)
-
(1998)
Journal of Urology
, vol.159
, Issue.6
, pp. 1810-1815
-
-
Kyprianou, N.1
Litvak, J.P.2
Borkowski, A.3
Alexander, R.4
Jacobs, S.C.5
-
33
-
-
0034662630
-
Suppression of human prostate cancer cell growth by α1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis
-
Kyprianou N, Benning CM. Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis. Cancer Res 2000;60:4550-5 (Pubitemid 32103639)
-
(2000)
Cancer Research
, vol.60
, Issue.16
, pp. 4550-4555
-
-
Kyprianou, N.1
Benning, C.M.2
-
34
-
-
0030690163
-
Transforming growth factor β1 transduced mouse prostate reconstitutions: II. Induction of apoptosis by doxazosin
-
DOI 10.1002/(SICI)1097-0045(19971101)33:3<157::AID-PROS2>3.0.CO;2-G
-
Yang G, Timme TL, Park SH, et al. Transforming growth factor beta 1 transduced mouse prostate reconstitutions: II. Induction of apoptosis by doxazosin. Prostate 1997;33:157-63 (Pubitemid 27509415)
-
(1997)
Prostate
, vol.33
, Issue.3
, pp. 157-163
-
-
Yang, G.1
Timme, T.L.2
Park, S.H.3
Wu, X.4
Wyllie, M.G.5
Thompson, T.C.6
-
35
-
-
0035996399
-
Induction of prostate apoptosis by α1-adrenoceptor antagonists: Mechanistic significance of the quinazoline component
-
DOI 10.1038/sj.pcan.4500561
-
Anglin IE, Glassman DT, Kyprianou N. Induction of prostate apoptosis by alpha1-adrenoceptor antagonists: Mechanistic significance of the quinazoline component. Prostate Cancer Prostatic Dis 2002;5:88-95 (Pubitemid 34777889)
-
(2002)
Prostate Cancer and Prostatic Diseases
, vol.5
, Issue.2
, pp. 88-95
-
-
Anglin, I.E.1
Glassman, D.T.2
Kyprianou, N.3
-
36
-
-
0029899625
-
Apoptotic versus proliferative activities in human benign prostatic hyperplasia
-
DOI 10.1016/S0046-8177(96)90396-2
-
Kyprianou N, Tu H, Jacobs SC. Apoptotic versus proliferative activities in human benign prostatic hyperplasia. Hum Pathol 1996;27:668-75 (Pubitemid 26240318)
-
(1996)
Human Pathology
, vol.27
, Issue.7
, pp. 668-675
-
-
Kyprianou, N.1
Tu, H.2
Jacobs, S.C.3
-
37
-
-
1642417428
-
1-Blockers on Prostate Cancer Growth: A Myth or an Inviting Reality?
-
DOI 10.1002/pros.10357
-
Tahmatzopoulos A, Kyprianou N. Apoptotic impact of alpha1-blockers on prostate cancer growth: A myth or an inviting reality? Prostate 2004;59:91-100 (Pubitemid 38387846)
-
(2004)
Prostate
, vol.59
, Issue.1
, pp. 91-100
-
-
Tahmatzopoulos, A.1
Kyprianou, N.2
-
38
-
-
2142800081
-
The alpha1-adrenoceptor antagonist terazosin induces prostate cancer cell death through a p53 and rb independent pathway
-
Xu K, Wang X, Ling PM, et al. The alpha1-adrenoceptor antagonist terazosin induces prostate cancer cell death through a p53 and rb independent pathway. Oncol Rep 2003;10:1555-60
-
(2003)
Oncol. Rep.
, vol.10
, pp. 1555-1560
-
-
Xu, K.1
Wang, X.2
Ling, P.M.3
-
39
-
-
0037304344
-
Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells
-
Pan SL, Guh JH, Huang YW, et al. Identification of apoptotic and antiangiogenic activities of terazosin in human prostate cancer and endothelial cells. J Urol 2003;169:724-9
-
(2003)
J. Urol.
, vol.169
, pp. 724-729
-
-
Pan, S.L.1
Guh, J.H.2
Huang, Y.W.3
-
40
-
-
0035399469
-
Reduction of human prostate tumor vascularity by the α1- adrenoceptor antagonist terazosin
-
DOI 10.1002/pros.1083
-
Keledjian K, Borkowski A, Kim G, et al. Reduction of human prostate tumor vascularity by the alpha1-adrenoceptorantagonist terazosin. Prostate 2001;48:71-8 (Pubitemid 32613870)
-
(2001)
Prostate
, vol.48
, Issue.2
, pp. 71-78
-
-
Keledjian, K.1
Borkowski, A.2
Kim, G.3
Isaacs, J.T.4
Jacobs, S.C.5
Kyprianou, N.6
-
41
-
-
28144434596
-
1-adrenergic receptor antagonists: Novel therapy for pituitary adenomas
-
DOI 10.1210/me.2004-0471
-
Fernando MA, Heaney AP. alpha1-adrenergic receptor antagonists: novel therapy for pituitary adenomas. Mol Endocrinol 2005;19:3085-96 (Pubitemid 41697723)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.12
, pp. 3085-3096
-
-
Fernando, M.A.1
Heaney, A.P.2
-
42
-
-
37149057007
-
1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-κB signalling to induce breast cancer cell apoptosis
-
DOI 10.1016/j.ejca.2007.10.002, PII S0959804907008027
-
Hui H, Fernando MA, Heaney AP. The alpha1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-kappaB signalling to induce breast cancer cell apoptosis. Eur J Cancer 2008;44:160-6 (Pubitemid 350256942)
-
(2008)
European Journal of Cancer
, vol.44
, Issue.1
, pp. 160-166
-
-
Hui, H.1
Fernando, M.A.2
Heaney, A.P.3
-
43
-
-
0032101088
-
Alpha-blockade therapy for benign prostatic hyperplasia: From a nonselective to a more selective alpha(1A)-adrenergic antagonist
-
DOI 10.1016/S0090-4295(98)00140-X, PII S009042959800140X
-
Beduschi MC, Beduschi R, Oesterling JE. Alpha-blockade therapy for benign prostatic hyperplasia: From a nonselective to a more selective alpha1A-adrenergic antagonist. Urology 1998;51:861-72 (Pubitemid 28240842)
-
(1998)
Urology
, vol.51
, Issue.6
, pp. 861-872
-
-
Beduschi, M.C.1
Beduschi, R.2
Oesterling, J.E.3
-
44
-
-
0036247603
-
Tamsulosin: A review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms
-
Dunn CJ, Matheson A, Faulds DM. Tamsulosin: A review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms. Drugs Aging 2002;19:135-61 (Pubitemid 34494035)
-
(2002)
Drugs and Aging
, vol.19
, Issue.2
, pp. 135-161
-
-
Dunn, C.J.1
Matheson, A.2
Faulds, D.M.3
-
45
-
-
0034806234
-
Worldwide experience with alfuzosin and tamsulosin
-
DOI 10.1016/S0090-4295(01)01335-8, PII S0090429501013358
-
Michel MC, Flannery MT, Narayan P. Worldwide experience with alfuzosin and tamsulosin. Urology 2001;58:508-16 (Pubitemid 32904489)
-
(2001)
Urology
, vol.58
, Issue.4
, pp. 508-516
-
-
Michel, M.C.1
Flannery, M.T.2
Narayan, P.3
-
46
-
-
33846072087
-
1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents
-
DOI 10.2174/156802607779318244
-
Rosini M, Bolognesi ML, Giardina D, et al. Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. Curr Top Med Chem 2007;7:147-62 (Pubitemid 46062387)
-
(2007)
Current Topics in Medicinal Chemistry
, vol.7
, Issue.2
, pp. 147-162
-
-
Rosini, M.1
Bolognesi, M.L.2
Giardina, D.3
Minarini, A.4
Tumiatti, V.5
Melchiorre, C.6
-
47
-
-
33749572713
-
1A-adrenoceptor-selective antagonist for treating benign prostatic hyperplasia: Results of a phase III randomized, placebo-controlled, double-blind study in Japanese men
-
DOI 10.1111/j.1464-410X.2006.06448.x
-
Kawabe K, Yoshida M, Homma Y. Silodosin, a new alpha1A-adrenoceptor- selective antagonist for treating benign prostatic hyperplasia: Results of a phase III randomized, placebo-controlled, double-blind study in Japanese men. BJU Int 2006;98:1019-24 (Pubitemid 44536452)
-
(2006)
BJU International
, vol.98
, Issue.5
, pp. 1019-1024
-
-
Kawabe, K.1
Yoshida, M.2
Homma, Y.3
-
48
-
-
79952483524
-
Silodosin in the treatment of benign prostatic hyperplasia
-
Rossi M, Roumeguere T. Silodosin in the treatment of benign prostatic hyperplasia. Drug Des Devel Ther 2010;4:291-7
-
(2010)
Drug Des. Devel. Ther.
, vol.4
, pp. 291-297
-
-
Rossi, M.1
Roumeguere, T.2
-
49
-
-
77957142514
-
Selective alpha1A-blocker improves bladder storage function in rats via suppression of C-fiber afferent activity
-
Yokoyama O, Ito H, Aoki Y, et al. Selective alpha1A-blocker improves bladder storage function in rats via suppression of C-fiber afferent activity. World J Urol 2010;28:609-14
-
(2010)
World J. Urol.
, vol.28
, pp. 609-614
-
-
Yokoyama, O.1
Ito, H.2
Aoki, Y.3
-
50
-
-
79551473561
-
Silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: Results of an international randomized double-blind placebo- and active-controlled clinical trial performed in europe
-
Chapple CR, Montorsi F, Tammela TL, et al. Silodosin therapy for lower urinary tract symptoms in men with suspected benign prostatic hyperplasia: Results of an international, randomized, double-blind, placebo- and active-controlled clinical trial performed in europe. Eur Urol 2011;59:342-52
-
(2011)
Eur. Urol.
, vol.59
, pp. 342-352
-
-
Chapple, C.R.1
Montorsi, F.2
Tammela, T.L.3
-
51
-
-
78650196744
-
Silodosin for the treatment of benign prostatic hyperplasia: Pharmacology and cardiovascular tolerability
-
Lepor H, Hill LA. Silodosin for the treatment of benign prostatic hyperplasia: Pharmacology and cardiovascular tolerability. Pharmacotherapy 2010;30:1303-12
-
(2010)
Pharmacotherapy
, vol.30
, pp. 1303-1312
-
-
Lepor, H.1
Hill, L.A.2
-
52
-
-
0034799139
-
A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor
-
Ciardiello F, Tortora G. A novel approach in the treatment of cancer: Targeting the epidermal growth factor receptor. Clin Cancer Res 2001;7:2958-70 (Pubitemid 32963812)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.10
, pp. 2958-2970
-
-
Ciardiello, F.1
Tortora, G.2
-
53
-
-
77956268839
-
Understanding resistance to EGFR inhibitors-impact on future treatment strategies
-
Wheeler DL, Dunn EF, Harari PM. Understanding resistance to EGFR inhibitors-impact on future treatment strategies. Nat Rev Clin Oncol 2010;7:493-507
-
(2010)
Nat. Rev. Clin. Oncol.
, vol.7
, pp. 493-507
-
-
Wheeler, D.L.1
Dunn, E.F.2
Harari, P.M.3
-
54
-
-
77949437037
-
Quinazoline-urea new protein kinase inhibitors in treatment of prostate cancer
-
Garofalo A, Goossens L, Lemoine A, et al. Quinazoline-urea, new protein kinase inhibitors in treatment of prostate cancer. J Enzyme Inhib Med Chem 2010;25:158-71
-
(2010)
J. Enzyme Inhib. Med. Chem.
, vol.25
, pp. 158-171
-
-
Garofalo, A.1
Goossens, L.2
Lemoine, A.3
-
55
-
-
78649505476
-
Design syn thesis and DNA-binding of N-alkylanilino quinazoline derivatives
-
Garofalo A, Goossens L, Baldeyrou B, et al. Design, synthesis, and DNA-binding of N-alkyl(anilino) quinazoline derivatives. J Med Chem 2010;53:8089-103
-
(2010)
J. Med. Chem.
, vol.53
, pp. 8089-8103
-
-
Garofalo, A.1
Goossens, L.2
Baldeyrou, B.3
-
56
-
-
20144370978
-
AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
-
DOI 10.1158/0008-5472.CAN-04-4409
-
Wedge SR, Kendrew J, Hennequin LF, et al. AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 2005;65:4389-400 (Pubitemid 40775678)
-
(2005)
Cancer Research
, vol.65
, Issue.10
, pp. 4389-4400
-
-
Wedge, S.R.1
Kendrew, J.2
Hennequin, L.F.3
Valentine, P.J.4
Barry, S.T.5
Brave, S.R.6
Smith, N.R.7
James, N.H.8
Dukes, M.9
Curwen, J.O.10
Chester, R.11
Jackson, J.A.12
Boffey, S.J.13
Kilburn, L.L.14
Barnett, S.15
Richmond, G.H.P.16
Wadsworth, P.F.17
Walker, M.18
Bigley, A.L.19
Taylor, S.T.20
Cooper, L.21
Beck, S.22
Jurgensmeier, J.M.23
Ogilvie, D.J.24
more..
-
57
-
-
79952818552
-
Overview of anti-angiogenic agents in development for ovarian cancer
-
Burger RA. Overview of anti-angiogenic agents in development for ovarian cancer. Gynecol Oncol 2011;121:230-8
-
(2011)
Gynecol. Oncol.
, vol.121
, pp. 230-238
-
-
Burger, R.A.1
-
58
-
-
67651242368
-
Current status of cediranib: The rapid development of a novel anti-angiogenic therapy
-
Lindsay CR, MacPherson IR, Cassidy J. Current status of cediranib: The rapid development of a novel anti-angiogenic therapy. Future Oncol 2009;5:421-32
-
(2009)
Future Oncol.
, vol.5
, pp. 421-432
-
-
Lindsay, C.R.1
MacPherson, I.R.2
Cassidy, J.3
-
59
-
-
79953793443
-
Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer
-
Ulahannan SV, Brahmer JR. Antiangiogenic agents in combination with chemotherapy in patients with advanced non-small cell lung cancer. Cancer Invest 2011;29:325-37
-
(2011)
Cancer Invest.
, vol.29
, pp. 325-337
-
-
Ulahannan, S.V.1
Brahmer, J.R.2
-
60
-
-
77954218447
-
Molecularly targeted therapy in hepatocellular carcinoma
-
Huynh H. Molecularly targeted therapy in hepatocellular carcinoma. Biochem Pharmacol 2010;80:550-60
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 550-560
-
-
Huynh, H.1
-
61
-
-
77950851926
-
Recent advances and future directions in the management of metastatic renal cell carcinoma
-
Ansari J, Glaholm J, McMenemin R, et al. Recent advances and future directions in the management of metastatic renal cell carcinoma. Anticancer Agents Med Chem 2010;10:225-35
-
(2010)
Anticancer Agents Med. Chem.
, vol.10
, pp. 225-235
-
-
Ansari, J.1
Glaholm, J.2
McMenemin, R.3
-
62
-
-
77749261166
-
Tyrosine kinase inhibitors to treat liver cancer
-
Huynh H. Tyrosine kinase inhibitors to treat liver cancer. Expert Opin Emerg Drugs 2010;15:13-26
-
(2010)
Expert Opin. Emerg. Drugs
, vol.15
, pp. 13-26
-
-
Huynh, H.1
-
64
-
-
67649091076
-
VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer
-
Gerstner ER, Duda DG, di Tomaso E, et al. VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer. Nat Rev Clin Oncol 2009;6:229-36
-
(2009)
Nat. Rev. Clin. Oncol.
, vol.6
, pp. 229-236
-
-
Gerstner, E.R.1
Duda, D.G.2
Di Tomaso, E.3
-
65
-
-
58949099316
-
Targeting angiogenesis in the treatment of lung cancer
-
Wheatley-Price P, Shepherd FA. Targeting angiogenesis in the treatment of lung cancer. J Thorac Oncol 2008;3:1173-84
-
(2008)
J. Thorac. Oncol.
, vol.3
, pp. 1173-1184
-
-
Wheatley-Price, P.1
Shepherd, F.A.2
-
66
-
-
70349311608
-
Cediranib: Profile of a novel anti-angiogenic agent in patients with glioblastoma
-
Dietrich J, Wang D, Batchelor TT. Cediranib: Profile of a novel anti-angiogenic agent in patients with glioblastoma. Expert Opin Investig Drugs 2009;18:1549-57
-
(2009)
Expert Opin. Investig Drugs
, vol.18
, pp. 1549-1557
-
-
Dietrich, J.1
Wang, D.2
Batchelor, T.T.3
-
67
-
-
79952438211
-
Design, synthesis and antitumor evaluation of phenyl n-mustard- quinazoline conjugates
-
Marvania B, Lee PC, Chaniyara R, et al. Design, synthesis and antitumor evaluation of phenyl n-mustard-quinazoline conjugates. Bioorg Med Chem 2011;19:1987-98
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 1987-1998
-
-
Marvania, B.1
Lee, P.C.2
Chaniyara, R.3
-
68
-
-
78650719442
-
Design syn thesis and biological evaluation of novel water-soluble N-mustards as potential anticancer agents
-
Kapuriya N, Kakadiya R, Dong H, et al. Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents. Bioorg Med Chem 2011;19:471-85
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 471-485
-
-
Kapuriya, N.1
Kakadiya, R.2
Dong, H.3
-
69
-
-
78650756956
-
Novel bifunctional alkylating agents 510-dihydropyrrolo 1 2-b isoquinoline derivatives synthesis and biological activity
-
Chaniyara R, Kapuriya N, Dong H, et al. Novel bifunctional alkylating agents, 5,10-dihydropyrrolo[1,2-b] isoquinoline derivatives, synthesis and biological activity. Bioorg Med Chem 2011;19:275-86
-
(2011)
Bioorg. Med. Chem.
, vol.19
, pp. 275-286
-
-
Chaniyara, R.1
Kapuriya, N.2
Dong, H.3
-
70
-
-
0038792746
-
Quinazoline-based α1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-β signalling and IκBα induction
-
DOI 10.1038/sj.bjc.6600961
-
Partin JV, Anglin IE, Kyprianou N. Quinazoline-based alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and IkappaBalpha induction. Br J Cancer 2003;88:1615-21 (Pubitemid 36713791)
-
(2003)
British Journal of Cancer
, vol.88
, Issue.10
, pp. 1615-1621
-
-
Partin, J.V.1
Anglin, I.E.2
Kyprianou, N.3
-
71
-
-
31544446659
-
Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway
-
DOI 10.1158/0008-5472.CAN-05-2039
-
Garrison JB, Kyprianou N. Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway. Cancer Res 2006;66:464-72 (Pubitemid 43166055)
-
(2006)
Cancer Research
, vol.66
, Issue.1
, pp. 464-472
-
-
Garrison, J.B.1
Kyprianou, N.2
-
72
-
-
3042754728
-
Pharmacological exploitation of the α1-adrenoreceptor antagonist doxazosin to develop a novel class of antitumor agents that block intracellular protein kinase B/Akt activation
-
DOI 10.1021/jm049752k
-
Shaw YJ, Yang YT, Garrison JB, et al. Pharmacological exploitation of the alpha1-adrenoreceptor antagonist doxazosin to develop a novel class of antitumor agents that block intracellular protein kinase B/Akt activation. J Med Chem 2004;47:4453-62 (Pubitemid 39096833)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.18
, pp. 4453-4462
-
-
Shaw, Y.-J.1
Yang, Y.-T.2
Garrison, J.B.3
Kyprianou, N.4
Chen, C.-S.5
-
73
-
-
37049031489
-
Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity
-
DOI 10.1158/0008-5472.CAN-07-1662
-
Garrison JB, Shaw YJ, Chen CS, Kyprianou N. Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity. Cancer Res 2007;67:11344-52 (Pubitemid 350248561)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11344-11352
-
-
Garrison, J.B.1
Shaw, Y.-J.2
Chen, C.-S.3
Kyprianou, N.4
-
74
-
-
79953237742
-
Anoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma
-
Sakamoto S, Schwarze S, Kyprianou N. Anoikis disruption of focal adhesion-Akt signaling impairs renal cell carcinoma. Eur Urol 2011;59:734-44
-
(2011)
Eur. Urol.
, vol.59
, pp. 734-744
-
-
Sakamoto, S.1
Schwarze, S.2
Kyprianou, N.3
-
75
-
-
49449113807
-
Discovery of 2-chloro-N-4-methoxyphenyl-N-methylquinazolin-4- amine EP128265 MPI-0441138 as a potent inducer of apoptosis with high in vivo activity
-
Sirisoma N, Kasibhatla S, Pervin A, et al. Discovery of 2-chloro-N-(4- methoxyphenyl)-N-methylquinazolin-4- amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in vivo activity. J Med Chem 2008;51:4771-9
-
(2008)
J. Med. Chem.
, vol.51
, pp. 4771-4779
-
-
Sirisoma, N.1
Kasibhatla, S.2
Pervin, A.3
-
76
-
-
33645999665
-
Identification preparation and characterization of several polymorphs and solvates of terazosin hydrochloride
-
Bauer J, Morley J, Spanton S, et al. Identification, preparation, and characterization of several polymorphs and solvates of terazosin hydrochloride. J Pharm Sci 2006;95:917-28
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 917-928
-
-
Bauer, J.1
Morley, J.2
Spanton, S.3
-
77
-
-
0242362589
-
1-Adrenoreceptors
-
Rosini M, Antonello A, Cavalli A, et al. Prazosin-related compounds. Effect of transforming the piperazinylquinazoline moiety into an aminomethyltetrahydroacridine system on the affinity for alpha1-adrenoreceptors. J Med Chem 2003;46:4895-903 (Pubitemid 37352029)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.23
, pp. 4895-4903
-
-
Rosini, M.1
Antonello, A.2
Cavalli, A.3
Bolognesi, M.L.4
Minarini, A.5
Marucci, G.6
Poggesi, E.7
Leonardi, A.8
Melchiorre, C.9
-
78
-
-
0035253863
-
1-adrenoreceptor subtypes
-
DOI 10.1021/jm000995w
-
Bolognesi ML, Marucci G, Angeli P, et al. Analogues of prazosin that bear a benextramine-related polyamine backbone exhibit different antagonism toward alpha1-adrenoreceptor subtypes. J. Med. Chem. 2001;44:362-71 (Pubitemid 32113583)
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, Issue.3
, pp. 362-371
-
-
Bolognesi, M.L.1
Marucci, G.2
Angeli, P.3
Buccioni, M.4
Minarini, A.5
Rosini, M.6
Tumiatti, V.7
Melchiorre, C.8
-
79
-
-
0036287769
-
1-adrenergic receptors
-
Manetti F, Corelli F, Strappaghetti G, Botta M. Arylpiperazines with affinity toward alpha1-adrenergic receptors. Curr Med Chem 2002;9:1303-21 (Pubitemid 34693070)
-
(2002)
Current Medicinal Chemistry
, vol.9
, Issue.13
, pp. 1303-1321
-
-
Manetti, F.1
Corelli, F.2
Strappaghetti, G.3
Botta, M.4
-
80
-
-
1542301641
-
1-adrenoceptor binding properties of new arylpiperazine derivatives bearing a flavone nucleus as the terminal heterocyclic molecular portion
-
DOI 10.1016/j.bmc.2003.12.033, PII S0968089604000148
-
Betti L, Floridi M, Giannaccini G, et al. Design, synthesis, and alpha1-adrenoceptor binding properties of new arylpiperazine derivatives bearing a flavone nucleus as the terminal heterocyclic molecular portion. Bioorg Med Chem 2004;12:1527-35 (Pubitemid 38296543)
-
(2004)
Bioorganic and Medicinal Chemistry
, vol.12
, Issue.6
, pp. 1527-1535
-
-
Betti, L.1
Floridi, M.2
Giannaccini, G.3
Manetti, F.4
Paparelli, C.5
Strappaghetti, G.6
Botta, M.7
-
81
-
-
0032474531
-
1-adrenoceptor subtypes selective antagonists: Design, synthesis and biological activity of cystazosin, an α(1D)-adrenoceptor antagonist
-
DOI 10.1016/S0960-894X(98)00217-0, PII S0960894X98002170
-
Minarini A, Budriesi R, Chiarini A, et al. Search for alpha1-adrenoceptor subtypes selective antagonists: Design, synthesis and biological activity of cystazosin, an alpha1D-adrenoceptor antagonist. Bioorg Med Chem Lett 1998;8:1353-8 (Pubitemid 28261301)
-
(1998)
Bioorganic and Medicinal Chemistry Letters
, vol.8
, Issue.11
, pp. 1353-1358
-
-
Minarini, A.1
Budriesi, R.2
Chiarini, A.3
Leonardi, A.4
Melchiorre, C.5
-
82
-
-
0027405060
-
Structure-activity relationships in prazosin-related compounds. 2. Role of the piperazine ring on α-blocking activity
-
Giardina D, Gulini U, Massi M, et al. Structure-activity relationships in prazosin-related compounds. 2. Role of the piperazine ring on alpha-blocking activity. J. Med. Chem. 1993;36:690-8 (Pubitemid 23105722)
-
(1993)
Journal of Medicinal Chemistry
, vol.36
, Issue.6
, pp. 690-698
-
-
Giardina, D.1
Gulini, U.2
Massi, M.3
Piloni, M.G.4
Pompei, P.5
Rafaiani, G.6
Melchiorre, C.7
-
83
-
-
0028810794
-
Receptor binding profile of cyclazosin a new alpha1B-adrenoceptor antagonist
-
Giardina D, Crucianelli M, Melchiorre C, et al. Receptor binding profile of cyclazosin, a new alpha1B-adrenoceptor antagonist. Eur J Pharmacol 1995;287:13-16
-
(1995)
Eur. J. Pharmacol.
, vol.287
, pp. 13-16
-
-
Giardina, D.1
Crucianelli, M.2
Melchiorre, C.3
-
84
-
-
33846915384
-
1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+)-cyclazosin
-
DOI 10.1016/j.bmc.2007.01.028, PII S0968089607000387
-
Sagratini G, Angeli P, Buccioni M, et al. Synthesis and alpha1-adrenoceptor antagonist activity of derivatives and isosters of the furan portion of (+) -cyclazosin. Bioorg Med Chem 2007;15:2334-45 (Pubitemid 46240916)
-
(2007)
Bioorganic and Medicinal Chemistry
, vol.15
, Issue.6
, pp. 2334-2345
-
-
Sagratini, G.1
Angeli, P.2
Buccioni, M.3
Gulini, U.4
Marucci, G.5
Melchiorre, C.6
Leonardi, A.7
Poggesi, E.8
Giardina, D.9
-
85
-
-
68549101741
-
Doxazosin-related alpha1-adrenoceptor antagonists with prostate antitumor activity
-
Giardina D, Martarelli D, Sagratini G, et al. Doxazosin-related alpha1-adrenoceptor antagonists with prostate antitumor activity. J. Med. Chem. 2009;52:4951-4
-
(2009)
J. Med. Chem.
, vol.52
, pp. 4951-4954
-
-
Giardina, D.1
Martarelli, D.2
Sagratini, G.3
-
89
-
-
84867419830
-
Overcoming tumor multidrug resistance using drugs able to evade P-glycoproteinor to exploit its expression
-
published online 3 March 2011 doi: 10.1002/med.20239
-
Nobili S, Landini I, Mazzei T, Mini E. Overcoming tumor multidrug resistance using drugs able to evade P-glycoproteinor to exploit its expression. Med Res Rev 2011;published online 3 March 2011; doi: 10.1002/med.20239
-
(2011)
Med. Res. Rev.
-
-
Nobili, S.1
Landini, I.2
Mazzei, T.3
Mini, E.4
-
90
-
-
0030924052
-
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein
-
USA
-
Dey S, Ramachandra M, Pastan I, et al. Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. Proc Natl Acad Sci USA 1997;94:10594-9
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 10594-10599
-
-
Dey, S.1
Ramachandra, M.2
Pastan, I.3
-
91
-
-
0021280915
-
Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha 1-adrenergic receptor
-
Seidman CE, Hess HJ, Homcy CJ, Graham RM. Synthesis and characterization of a radioiodinated photoaffinity probe for the alpha 1-adrenergic receptor. Hypertension 1984;6-I 7-11
-
(1984)
Hypertension
, vol.6
, Issue.1
, pp. 7-11
-
-
Seidman, C.E.1
Hess, H.J.2
Homcy, C.J.3
Graham, R.M.4
-
93
-
-
36348967305
-
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance
-
DOI 10.1158/0008-5472.CAN-07-2686
-
Shi Z, Peng XX, Kim IW, et al. Erlotinib (tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Cancer Res 2007;67:11012-20 (Pubitemid 350145931)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 11012-11020
-
-
Shi, Z.1
Peng, X.-X.2
Kim, I.-W.3
Shukla, S.4
Si, Q.-S.5
Robey, R.W.6
Bates, S.E.7
Shen, T.8
Ashby Jr., C.R.9
Fu, L.-W.10
Ambudkar, S.V.11
Chen, Z.-S.12
-
94
-
-
77954892297
-
Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib nilotinib and dasatinib
-
Dohse M, Scharenberg C, Shukla S, et al. Comparison of ATP-binding cassette transporter interactions with the tyrosine kinase inhibitors imatinib, nilotinib, and dasatinib. Drug Metab Dispos 2010;38:1371-80
-
(2010)
Drug Metab. Dispos.
, vol.38
, pp. 1371-1380
-
-
Dohse, M.1
Scharenberg, C.2
Shukla, S.3
-
95
-
-
77955553428
-
Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study
-
El-Azab AS, Al-Omar MA, Abdel-Aziz AA, et al. Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study. Eur J. Med. Chem. 2010;45:4188-98
-
(2010)
Eur J. Med. Chem.
, vol.45
, pp. 4188-4198
-
-
El-Azab, A.S.1
Al-Omar, M.A.2
Abdel-Aziz, A.A.3
-
96
-
-
18444392731
-
Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion
-
DOI 10.1002/jcb.20240
-
Keledjian K, Garrison JB, Kyprianou N. Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion. J Cell Biochem 2005;94:374-88 (Pubitemid 41420315)
-
(2005)
Journal of Cellular Biochemistry
, vol.94
, Issue.2
, pp. 374-388
-
-
Keledjian, K.1
Garrison, J.B.2
Kyprianou, N.3
-
97
-
-
77951480423
-
Targeting anoikis resistance in prostate cancer metastasis
-
Sakamoto S, Kyprianou N. Targeting anoikis resistance in prostate cancer metastasis. Mol Aspects Med 2010;31:205-14
-
(2010)
Mol. Aspects Med.
, vol.31
, pp. 205-214
-
-
Sakamoto, S.1
Kyprianou, N.2
-
98
-
-
0037376011
-
Doxazosin and terazosin suppress prostate growth by inducing apoptosis: Clinical significance
-
DOI 10.1097/01.ju.0000033280.29453.72
-
Kyprianou N. Doxazosin and terazosin suppress prostate growth by inducing apoptosis: Clinical significance. J Urol 2003;169:1520-5 (Pubitemid 36323836)
-
(2003)
Journal of Urology
, vol.169
, Issue.4
, pp. 1520-1525
-
-
Kyprianou, N.1
|