Rapamycin inhibits α1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes: Evidence for involvement of p70 S6 kinase

Circulation Research

Volumn 81, Issue 2, 1997, Pages 176-186

  Boluyt, Marvin O ^a   Zheng, Jing Sheng ^a   Younes, Antoine ^b   Long, Xilin ^a   O'Neill, Lydia ^a   Silverman, Howard ^c   Lakatta, Edward G ^a   Crow, Michael T ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Immunosuppressant drug; Phosphatidylinositol 3 kinase; Rapamycin; Ribosomal S6 kinase; 1 adrenergic receptor

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ACTIN; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ATRIAL NATRIURETIC FACTOR; IMMUNOSUPPRESSIVE AGENT; MACROLIDE; MESSENGER RNA; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; RAPAMYCIN; RNA;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; GENE EXPRESSION; GENE INDUCTION; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RAT; RNA SYNTHESIS;

EID: 0030807080     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.81.2.176     Document Type: Article

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