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Volumn 88, Issue 3, 2000, Pages 281-309

α1-adrenergic receptor regulation: Basic science and clinical implications

Author keywords

Adrenergic receptor; Alpha 1; Hyperplasia; Hypertrophy; Structure function; Transcription

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 4 (4 NITROPHENYL) 3,5 PYRIDINEDICARBOXYLIC ACID [3 (4,4 DIPHENYL 1 PIPERIDINYL)PROPYL]AMIDE METHYL ESTER; 2 [2 (4 HYDROXYPHENYL)ETHYLAMINOMETHYL]TETRALONE; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 5 CHLORO N [2 (2 CYCLOPROPYLMETHOXYPHENOXY)ETHYL] ALPHA,ALPHA DIMETHYL 1H INDOLE 3 ETHANAMINE; 5 METHYLURAPIDIL; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; 8 [3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]PROPYLCARBAMOYL] 3 METHYLFLAVONE; ALFUZOSIN; ALPHA 1 ADRENERGIC RECEPTOR; BETAXOLOL; CLONIDINE; CYCLAZOCINE; DEXMEDETOMIDINE; GUANINE NUCLEOTIDE BINDING PROTEIN; IDAZOXAN; INDORAMIN; METOPROLOL; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NIGULDIPINE; PHENTOLAMINE; PINDOLOL; PRAZOSIN; RAUWOLSCINE; RECEPTOR SUBTYPE; SALBUTAMOL; SPIPERONE; TAMSULOSIN; TERAZOSIN; UNINDEXED DRUG; YOHIMBINE;

EID: 0034452038     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(00)00092-9     Document Type: Review
Times cited : (216)

References (242)
  • 1
    • 0027263925 scopus 로고
    • Benign prostatic hyperplasia poorly correlated with symptoms
    • (1993) Br Med J , vol.307 , pp. 201-211
    • Abrams, P.1
  • 11
    • 0032129267 scopus 로고    scopus 로고
    • Selective activation of alpha1A-adrenergic receptors in neonatal cardiac myocytes is sufficient to cause hypertrophy and differential regulation of alpha1-adrenergic receptor subtype mRNAs
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 1515-1523
    • Autelitano, D.J.1    Woodcock, E.A.2
  • 15
    • 0027992548 scopus 로고
    • Effect of alpha 1-adrenergic receptor antagonists on susceptibility to malignant arrhythmias: Protection from ventricular fibrillation
    • (1994) J Cardiovasc Pharmacol , vol.24 , pp. 394-402
    • Billman, G.E.1
  • 25
    • 0025351645 scopus 로고
    • Alpha-adrenergic blockers for the treatment of benign prostatic hyperplasia
    • (1990) Urol Clin North Am , vol.17 , pp. 641-649
    • Caine, M.1
  • 29
    • 0028998873 scopus 로고
    • Alpha-adrenergic blocking drugs in bladder outflow obstruction: What potential has alpha 1-adrenoceptor selectivity?
    • (1995) Br J Urol , vol.1 , pp. 47-55
    • Chapple, C.R.1
  • 30
    • 0027982872 scopus 로고
    • The pathophysiological changes in the bladder obstructed by benign prostatic hyperplasia
    • (1994) Br J Urol , vol.73 , pp. 117-123
    • Chapple, C.R.1    Smith, D.2
  • 49
    • 0028169668 scopus 로고
    • Identification of the α1D-adrenoceptor sybtype in rabbit arteries and the human saphenous vein using the polymerase chain reaction
    • (1994) Eur J Pharmacol , vol.268 , pp. 393-398
    • Diehl, N.L.1    Shreeve, S.M.2
  • 51
    • 0030699386 scopus 로고    scopus 로고
    • Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor
    • (1997) J Biol Chem , vol.272 , pp. 28712-28719
    • Diviani, D.1    Lattion, A.L.2    Cotecchia, S.3
  • 60
    • 0033573849 scopus 로고    scopus 로고
    • Alpha 1B-adrenoceptor interacts with multiple sites of transglutaminase: II. Characteristics of the interaction in binding and activation
    • (1999) Biochemistry , vol.38 , pp. 2224-2232
    • Feng, J.F.1    Gray, C.D.2    Im, M.J.3
  • 66
    • 0027491115 scopus 로고
    • Isolation and characterization of the gene encoding the rat alpha 1B adrenergic receptor
    • (1993) Gene , vol.131 , pp. 243-247
    • Gao, B.1    Kunos, G.2
  • 67
    • 0028176734 scopus 로고
    • Transcription of the rat alpha 1B adrenergic receptor gene in liver is controlled by three promoters
    • (1994) J Biol Chem , vol.269 , pp. 15762-15767
    • Gao, B.1    Kunos, G.2
  • 68
    • 0033610796 scopus 로고    scopus 로고
    • Cell type-specific transcriptional activation and suppression of the alpha1B adrenergic receptor gene middle promoter by nuclear factor 1
    • (1998) J Biol Chem , vol.273 , pp. 31784-31787
    • Gao, B.1    Kunos, G.2
  • 69
    • 0028986630 scopus 로고
    • The rat alpha 1B adrenergic receptor gene middle promoter contains multiple binding sites for sequence-specific proteins including a novel ubiquitous transcription factor
    • (1995) J Biol Chem , vol.270 , pp. 5614-5619
    • Gao, B.1    Spector, M.S.2    Kunos, G.3
  • 70
    • 0029850085 scopus 로고    scopus 로고
    • Transcriptional regulation of alpha(1b) adrenergic receptors (alpha(1b)AR) by nuclear factor 1 (NF1): A decline in the concentration of NF1 correlates with the downregulation of alpha(1b)AR gene expression in regenerating liver
    • (1996) Mol Cell Biol , vol.16 , pp. 5997-6008
    • Gao, B.1    Jiang, L.2    Kunos, G.3
  • 71
    • 0031439584 scopus 로고    scopus 로고
    • Both the cyclic AMP response element and the activator protein 2 binding site mediate basal and cyclic AMP-induced transcription from the dominant promoter of the rat alpha 1B-adrenergic receptor gene in DDT1MF-2 cells
    • (1997) Mol Pharmacol , vol.52 , pp. 1019-1026
    • Gao, B.1    Chen, J.2    Johnson, C.3    Kunos, G.4
  • 72
    • 0031887276 scopus 로고    scopus 로고
    • Histone H1 isoforms purified from rat liver bind nonspecifically to the nuclear factor 1 recognition sequence and serve as generalized transcriptional repressors
    • (1998) Mol Cell Biochem , vol.178 , pp. 187-196
    • Gao, B.1    Jaffe, H.2    Kunos, G.3
  • 100
    • 0031052087 scopus 로고    scopus 로고
    • Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase
    • (1997) J Biol Chem , vol.272 , pp. 4219-4224
    • Janknecht, R.1    Hunter, T.2
  • 101
  • 104
    • 0025738121 scopus 로고
    • Clinical implications of pathophysiologic changes in the midlife hypertensive patient
    • (1991) Am Heart J , vol.122 , pp. 886-891
    • Julius, S.1
  • 109
    • 0033514257 scopus 로고    scopus 로고
    • Appreciating alpha-adrenergic receptors and their role in ischemic left ventricular dysfunction
    • (1999) Circulation , vol.99 , pp. 468-471
    • Kern, M.J.1
  • 111
    • 0032872522 scopus 로고    scopus 로고
    • Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: Modulation by alpha- and beta-adrenoceptor agonists
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 171-180
    • Kimura, M.1    Ogihara, M.2
  • 131
    • 0020627679 scopus 로고
    • Identification of receptor mechanism mediating epinephrine-induced arrhythmias during halothane anesthesia in the dog
    • (1983) Anesthesiology , vol.59 , pp. 322-326
    • Maze, M.1    Smith, C.M.2
  • 140
  • 141
    • 0032698819 scopus 로고    scopus 로고
    • Beta-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors: Shifting the focus from inotropy to cyclic adenosine monophosphate
    • (1999) J Am Coll Cardiol , vol.34 , pp. 318-324
    • Movsesian, M.A.1
  • 144
    • 0032483381 scopus 로고    scopus 로고
    • Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase
    • (1998) J Biol Chem , vol.273 , pp. 22892-22898
    • Nagao, M.1    Yamauchi, J.2    Kaziro, Y.3    Itoh, H.4
  • 145
    • 0033544914 scopus 로고    scopus 로고
    • Cross-talk between alpha(1B)-adrenergic receptor (alpha(1B)AR) and interleukin-6 (IL-6) signaling pathways. Activation Of alpha(1b)ar inhibits il-6-activated stat3 in hepatic cells by a p42/44 mitogen-activated protein kinase-dependent mechanism
    • (1999) J Biol Chem , vol.274 , pp. 35492-35498
    • Nguyen, V.A.1    Gao, B.2
  • 159
    • 0033520912 scopus 로고    scopus 로고
    • Characteristics for a salt-bridge switch mutation of the alpha(1b) adrenergic receptor. Altered pharmacology and rescue of constitutive activity
    • (1999) J Biol Chem , vol.274 , pp. 34535-34538
    • Porter, J.E.1    Perez, D.M.2
  • 160
    • 0033981907 scopus 로고    scopus 로고
    • Influence of a lysine 331 counterion on the pK(a) of aspartic acid 125: Evidence for a salt-bridge interaction and role in alpha(1b)-adrenergic receptor activation
    • (2000) J Pharmacol Exp Ther , vol.292 , pp. 440-448
    • Porter, J.E.1    Perez, D.M.2
  • 161
  • 171
    • 0021172524 scopus 로고
    • Alpha-adrenergic blockade in diagnosis of detrusor instability secondary to infravesical obstruction
    • (1984) Urol Int , vol.39 , pp. 312-313
    • Reuther, K.1    Aagaard, J.2
  • 174
    • 0031916647 scopus 로고    scopus 로고
    • G protein-coupled receptors: Functional and mechanistic insights through altered gene expression
    • (1998) Physiol Rev , vol.78 , pp. 35-52
    • Rohrer, D.1    Kobilka, B.2
  • 190
    • 0034027033 scopus 로고    scopus 로고
    • Alpha1-adrenergic receptors in the lower urinary tract and vascular bed: Potential role for the alpha1d subtype in filling symptoms and effects of ageing on vascular expression
    • (1999) Br J Urol Int , vol.85 , Issue.SUPPL. 2 , pp. 6-11
    • Schwinn, D.A.1    Michelotti, G.A.2
  • 191
    • 0033067425 scopus 로고    scopus 로고
    • Molecular pharmacology of human alpha1-adrenergic receptors: Unique features of the alpha 1a-subtype
    • (1999) Eur Urol , vol.36 , pp. 7-10
    • Schwinn, D.A.1    Price, R.R.2
  • 197
    • 0031984164 scopus 로고    scopus 로고
    • Prospective study comparing hyoscyamine, doxazosin, and combination therapy for the treatment of urgency and frequency in women
    • (1998) Neurourol Urodyn , vol.17 , pp. 31-36
    • Serels, S.1    Stein, M.2
  • 199
    • 0020075138 scopus 로고
    • Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells: Cross striations, ultrastructure, and chronotropic response to isoproterenol
    • (1982) Circ Res , vol.50 , pp. 101-116
    • Simpson, P.1    Savion, S.2
  • 203
    • 0033980171 scopus 로고    scopus 로고
    • Roles of mitogen-activated protein kinases and protein kinase C in alpha(1A)-adrenoceptor-mediated stimulation of the sarcolemmal Na(+)-H(+) exchanger
    • (2000) Circ Res , vol.86 , pp. 214-220
    • Snabaitis, A.K.1    Yokoyama, H.2    Avkiran, M.3
  • 208
    • 0023681207 scopus 로고
    • Effect of bladder outlet obstruction on micturition reflex pathways in the rat
    • (1988) J Urol , vol.140 , pp. 864-871
    • Steers, W.D.1    De, G.W.2
  • 216
    • 0033515536 scopus 로고    scopus 로고
    • Signaling in myocardial hypertrophy: Life after calcineurin?
    • (1999) Circ Res , vol.84 , pp. 633-646
    • Sugden, P.H.1
  • 217
    • 0025223057 scopus 로고
    • Two pharmacologically distinct α1-adrenoceptor subtypes in the contraction of rabbit aorta: Each subtype couples with a different Ca2+ signalling mechanism and plays a different physiological role
    • (1990) Mol Pharmacol , vol.38 , pp. 725-736
    • Suzuki, E.1    Tsujimoto, G.2    Tamura, K.3    Hashimoto, K.4
  • 221
    • 0023156436 scopus 로고
    • Comparison of agonist-induced changes in beta- and alpha 1-adrenergic receptors of DDT1 MF-2 cells
    • (1987) Mol Pharmacol , vol.31 , pp. 58-68
    • Toews, M.L.1
  • 232
  • 235
    • 0032746326 scopus 로고    scopus 로고
    • Platelet-derived growth factor inhibits alpha1D-adrenergic receptor expression in vascular smooth muscle cells in vitro and ex vivo
    • (1999) Mol Pharmacol , vol.56 , pp. 1143-1151
    • Xin, X.1    Yang, N.2    Faber, J.E.3
  • 236
    • 0032732282 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB inhibits rat alpha1D-adrenergic receptor gene expression in vascular smooth muscle cells by inducing AP-2-like protein binding to alpha1D proximal promoter region
    • (1999) Mol Pharmacol , vol.56 , pp. 1152-1161
    • Xin, X.1    Yang, N.2    Faber, J.E.3


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