메뉴 건너뛰기




Volumn , Issue , 2009, Pages 327-354

MicroRNA: Biogenesis, regulation, and role in primary brain tumors

Author keywords

[No Author keywords available]

Indexed keywords


EID: 83155185149     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-00475-9_15     Document Type: Chapter
Times cited : (2)

References (141)
  • 1
    • 58149381996 scopus 로고    scopus 로고
    • MicroRNAs differentially expressed in ACTH secreting pituitary tumors
    • Amaral FC, Torres N, Saggioro F et al. (2009) MicroRNAs differentially expressed in ACTH secreting pituitary tumors. J Clin Endocrinol Metab 94:320-323.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 320-323
    • Amaral, F.C.1    Torres, N.2    Saggioro, F.3
  • 2
    • 7744223490 scopus 로고    scopus 로고
    • MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNA are required for methylation of the template chromosome
    • Bao N, Lye KW, Barton MK (2004) MicroRNA binding sites in Arabidopsis class III HD-ZIP mRNA are required for methylation of the template chromosome. Dev Cell 7:653-662.
    • (2004) Dev Cell , vol.7 , pp. 653-662
    • Bao, N.1    Lye, K.W.2    Barton, M.K.3
  • 3
    • 13944260434 scopus 로고    scopus 로고
    • Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
    • Baskerville S, Bartel DP (2005) Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 11:241-247.
    • (2005) RNA , vol.11 , pp. 241-247
    • Baskerville, S.1    Bartel, D.P.2
  • 4
    • 33746055678 scopus 로고    scopus 로고
    • MRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
    • Behm-Ansmant I, Rehwinkel J, Doerks T et al. (2006) mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev 20:1885-1898.
    • (2006) Genes Dev , vol.20 , pp. 1885-1898
    • Behm-Ansmant, I.1    Rehwinkel, J.2    Doerks, T.3
  • 6
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM et al. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3
  • 7
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated translational repression in human cells subjected to stress
    • Bhattacharyya SN, Habermacher R, Martine U et al. (2006) Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125:1111-1124.
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3
  • 8
    • 38349190243 scopus 로고    scopus 로고
    • MicroRNAs modulate the chemosensitivity of tumor cells
    • Blower PE, Chung JH, Verducci JS et al. (2008) MicroRNAs modulate the chemosensitivity of tumor cells. Mol Cancer Ther 7:1-9.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1-9
    • Blower, P.E.1    Chung, J.H.2    Verducci, J.S.3
  • 10
    • 18844459384 scopus 로고    scopus 로고
    • Mir-15a and mir-16-1 down-regulation in pituitary adenomas
    • Bottoni A, Piccin D, Tagliati F et al. (2005) Mir-15a and mir-16-1 down-regulation in pituitary adenomas. J Cell Physiol 204:280-285.
    • (2005) J Cell Physiol , vol.204 , pp. 280-285
    • Bottoni, A.1    Piccin, D.2    Tagliati, F.3
  • 11
    • 33845608588 scopus 로고    scopus 로고
    • Identification of differentially expressed micro- RNAs by microarray: A possible role for microRNA genes in pituitary adenomas
    • Bottoni A, Zatelli MC, Ferracin M et al. (2007) Identification of differentially expressed micro- RNAs by microarray: A possible role for microRNA genes in pituitary adenomas. J Cell Physiol 210:370-377.
    • (2007) J Cell Physiol , vol.210 , pp. 370-377
    • Bottoni, A.1    Zatelli, M.C.2    Ferracin, M.3
  • 12
    • 44449149903 scopus 로고    scopus 로고
    • Genetic and epigenetic silencing of microRNA-203 enhances abl1 and bcr-abl1 oncogene expression
    • Bueno MJ, de Castro IP, de Cedrón MG et al. (2008) Genetic and epigenetic silencing of microRNA-203 enhances abl1 and bcr-abl1 oncogene expression. Cancer Cell 13:496-506.
    • (2008) Cancer Cell , vol.13 , pp. 496-506
    • Bueno, M.J.1    De Castro, I.P.2    De Cedrón, M.G.3
  • 13
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped polyadenylated transcripts that can also function as mRNAs
    • Cai X, Hagedorn CH, Cullen BR (2004) Human microRNAs are processed from capped polyadenylated transcripts that can also function as mRNAs. RNA 10:1957-1966.
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 14
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro- RNA genes mir-15 and mir-16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M et al. (2002) Frequent deletions and down-regulation of micro- RNA genes mir-15 and mir-16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3
  • 15
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD et al. (2004) Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101:2999- 3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3
  • 16
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A et al. (2005) A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 353:1793-1801.
    • (2005) N Engl J Med , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 17
    • 40949137731 scopus 로고    scopus 로고
    • Hsa-mir-210 is induced by hypoxia and is an independent prognostic factor in breast cancer
    • Camps C, Buffa FM, Colella S et al. (2008) Hsa-mir-210 is induced by hypoxia and is an independent prognostic factor in breast cancer. Clin Cancer Res 14:1340-1348.
    • (2008) Clin Cancer Res , vol.14 , pp. 1340-1348
    • Camps, C.1    Buffa, F.M.2    Colella, S.3
  • 18
    • 34548668636 scopus 로고    scopus 로고
    • MiChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes
    • Castoldi M, Benes V, Hentze MW et al. (2007) MiChip: A microarray platform for expression profiling of microRNAs based on locked nucleic acid (LNA) oligonucleotide capture probes. Methods 43:146-152.
    • (2007) Methods , vol.43 , pp. 146-152
    • Castoldi, M.1    Benes, V.2    Hentze, M.W.3
  • 19
    • 35549005351 scopus 로고    scopus 로고
    • And now introducing mammalian mirtrons
    • Chan SP, Slack FJ (2007) And now introducing mammalian mirtrons. Dev Cell 13:605-607.
    • (2007) Dev Cell , vol.13 , pp. 605-607
    • Chan, S.P.1    Slack, F.J.2
  • 20
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65:6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 21
    • 37549008310 scopus 로고    scopus 로고
    • Widespread microRNA repression by Myc contributes to tumorigenesis
    • Chang TC, Yu D, Lee YS et al. (2008) Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 40:43-50.
    • (2008) Nat Genet , vol.40 , pp. 43-50
    • Chang, T.C.1    Yu, D.2    Lee, Y.S.3
  • 22
    • 29144470346 scopus 로고    scopus 로고
    • Real-time quantification of microRNAs by stemloop RT-PCR
    • Chen C, Ridzon DA, Broomer AJ et al. (2005) Real-time quantification of microRNAs by stemloop RT-PCR. Nucleic Acids Res 33:e179.
    • (2005) Nucleic Acids Res , vol.33 , pp. e179
    • Chen, C.1    Ridzon, D.A.2    Broomer, A.J.3
  • 23
    • 55949114921 scopus 로고    scopus 로고
    • MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G
    • Chen Y, Liu W, Chao T et al. (2008) MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett 272:197-205.
    • (2008) Cancer Lett , vol.272 , pp. 197-205
    • Chen, Y.1    Liu, W.2    Chao, T.3
  • 24
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to AGO2 for microRNA processing and gene silencing
    • Chendrimada TP, Gregory RI, Kumaraswamy E et al. (2005) TRBP recruits the Dicer complex to AGO2 for microRNA processing and gene silencing. Nature 436:740-744.
    • (2005) Nature , vol.436 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3
  • 25
    • 34249282938 scopus 로고    scopus 로고
    • MicroRNA silencing through RISC recruitment of EIF6
    • Chendrimada TP, Finn KJ, Ji X et al. (2007) MicroRNA silencing through RISC recruitment of EIF6. Nature 447:823-828.
    • (2007) Nature , vol.447 , pp. 823-828
    • Chendrimada, T.P.1    Finn, K.J.2    Ji, X.3
  • 26
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 27
    • 23044464236 scopus 로고    scopus 로고
    • Extensive modulation of a set of microRNAs in primary glioblastoma
    • Ciafrè SA, Galardi S, Mangiola A et al. (2005) Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 334:1351-1358.
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 1351-1358
    • Ciafrè, S.A.1    Galardi, S.2    Mangiola, A.3
  • 28
    • 25444520537 scopus 로고    scopus 로고
    • Mir-15 and mir-16 induce apoptosis by targeting BCL2
    • Cimmino A, Calin GA, Fabbri M et al. (2005) Mir-15 and mir-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102:13944-13949.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13944-13949
    • Cimmino, A.1    Calin, G.A.2    Fabbri, M.3
  • 29
    • 33745577150 scopus 로고    scopus 로고
    • A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
    • Clop A, Marcq F, Takeda H et al. (2006) A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet 38:813-818.
    • (2006) Nat Genet , vol.38 , pp. 813-818
    • Clop, A.1    Marcq, F.2    Takeda, H.3
  • 30
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered s-TRAIL in human gliomas
    • Corsten MF, Miranda R, Kasmieh R et al. (2007) MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered s-TRAIL in human gliomas. Cancer Res 67:8994-9000.
    • (2007) Cancer Res , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3
  • 32
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control Drosha-mediated micro- RNA maturation
    • Davis BN, Hilyard AC, Lagna G et al. (2008) SMAD proteins control Drosha-mediated micro- RNA maturation. Nature 454:56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3
  • 33
    • 58549109007 scopus 로고    scopus 로고
    • Potent inhibition of microRNA in vivo without degradation
    • Davis S, Propp S, Freier SM et al. (2009) Potent inhibition of microRNA in vivo without degradation. Nucleic Acids Res 37:70-77.
    • (2009) Nucleic Acids Res , vol.37 , pp. 70-77
    • Davis, S.1    Propp, S.2    Freier, S.M.3
  • 34
    • 33748310866 scopus 로고    scopus 로고
    • Detection of mammalian micro RNA expression by in situ hybridization with RNA oligonucleotides
    • Deo M, Yu JY, Chung KH et al. (2006) Detection of mammalian micro RNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn 235:2538-2548.
    • (2006) Dev Dyn , vol.235 , pp. 2538-2548
    • Deo, M.1    Yu, J.Y.2    Chung, K.H.3
  • 35
    • 33748302836 scopus 로고    scopus 로고
    • Augmentation of tumor angiogenesis by a Mycactivated microRNA cluster
    • Dews M, Homayouni A, Yu D et al. (2006) Augmentation of tumor angiogenesis by a Mycactivated microRNA cluster. Nat Genet 38:1060-1065.
    • (2006) Nat Genet , vol.38 , pp. 1060-1065
    • Dews, M.1    Homayouni, A.2    Yu, D.3
  • 36
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs S, Haber DA (2007) Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131:1097-1108.
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 37
    • 42449086421 scopus 로고    scopus 로고
    • Mir-148 targets human DNMT3b protein coding region
    • Duursma AM, Kedde M, Schrier M et al. (2008) Mir-148 targets human DNMT3b protein coding region. RNA 14:872-877.
    • (2008) RNA , vol.14 , pp. 872-877
    • Duursma, A.M.1    Kedde, M.2    Schrier, M.3
  • 38
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- And 22- nucleotide
    • Elbashir SM, Lendeckel W, Tuschl T (2001) RNA interference is mediated by 21- And 22- nucleotide. RNAs Genes Dev 15:188-200.
    • (2001) RNAs Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 39
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-269.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 40
    • 53549129980 scopus 로고    scopus 로고
    • Concerted microRNA control of hedgehog signalling in cerebellar neuronal progenitor and tumour cells
    • Ferretti E, Smaele ED, Miele E et al. (2008a) Concerted microRNA control of hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J 27:2616-2627.
    • (2008) EMBO J , vol.27 , pp. 2616-2627
    • Ferretti, E.1    Smaele, E.D.2    Miele, E.3
  • 42
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight? Nat Rev Genet 9:102-114.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 43
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK et al. (1998) Potent and specific genetic interference by doublestranded RNA in Caenorhabditis elegans. Nature 391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 44
    • 52049096593 scopus 로고    scopus 로고
    • Mir-451 and imatinib mesylate inhibit tumor growth of glioblastoma stem cells
    • Gal H, Pandi G, Kanner AA et al. (2008) Mir-451 and imatinib mesylate inhibit tumor growth of glioblastoma stem cells. Biochem Biophys Res Commun 376:86-90.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 86-90
    • Gal, H.1    Pandi, G.2    Kanner, A.A.3
  • 45
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A et al. (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 68:9125-9130.
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3
  • 46
    • 49749133953 scopus 로고    scopus 로고
    • Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
    • Gonzalez S, Pisano DG, Serrano M(2008) Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs. Cell Cycle 7:2601-2608.
    • (2008) Cell Cycle , vol.7 , pp. 2601-2608
    • Gonzalez, S.1    Pisano, D.G.2    Serrano, M.3
  • 47
    • 9144225636 scopus 로고    scopus 로고
    • The microprocessor complex mediates the genesis of microRNAs
    • Gregory RI, Yan KP, Amuthan G et al. (2004) The microprocessor complex mediates the genesis of microRNAs. Nature 432:235-240.
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1    Yan, K.P.2    Amuthan, G.3
  • 48
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory RI, Chendrimada TP, Cooch N et al. (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123:631-640.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3
  • 49
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
    • Grimson A, Farh KKH, Johnston WK et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27:91-105.
    • (2007) Mol Cell , vol.27 , pp. 91-105
    • Grimson, A.1    Farh, K.K.H.2    Johnston, W.K.3
  • 50
    • 34447115822 scopus 로고    scopus 로고
    • The multifunctional RNA-binding protein hnRNP A1 is required for processing of mir-18a
    • Guil S, Cáceres JF (2007) The multifunctional RNA-binding protein hnRNP A1 is required for processing of mir-18a. Nat Struct Mol Biol 14:591-596.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 591-596
    • Guil, S.1    Cáceres, J.F.2
  • 51
    • 0029024475 scopus 로고
    • Par-1 a gene required for establishing polarity in C. Elegans embryos encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S, Kemphues KJ (1995) Par-1 a gene required for establishing polarity in C. elegans embryos encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81:611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 52
    • 37349130959 scopus 로고    scopus 로고
    • Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing
    • Hafner M, Landgraf P, Ludwig J et al. (2008) Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods 44:3-12.
    • (2008) Methods , vol.44 , pp. 3-12
    • Hafner, M.1    Landgraf, P.2    Ludwig, J.3
  • 53
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D et al. (2000) An RNA-directed nuclease mediates posttranscriptional gene silencing in Drosophila cells. Nature 404:293-296.
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3
  • 54
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2 a link between genetic and biochemical analyses of RNAi
    • Hammond SM, Boettcher S, Caudy AA et al. (2001) Argonaute2 a link between genetic and biochemical analyses of RNAi. Science 293:1146-1150.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3
  • 55
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • Han J, Lee Y, Yeom KH et al. (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125:887-901.
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3
  • 56
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster mir-17-92 is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita Y, Osada H, Tatematsu Y et al. (2005) A polycistronic microRNA cluster mir-17-92 is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 65:9628- 9632.
    • (2005) Cancer Res , vol.65 , pp. 9628-9632
    • Hayashita, Y.1    Osada, H.2    Tatematsu, Y.3
  • 57
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He L, Thomson JM, Hemann MT et al. (2005) A microRNA polycistron as a potential human oncogene. Nature 435:828-833.
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3
  • 58
    • 36348973030 scopus 로고    scopus 로고
    • Derepression of microRNA-mediated protein translation inhibition by apolipoprotein b mRNAediting enzyme catalytic polypeptide-like 3g (APOBEC3G): And its family members
    • Huang J, Liang Z, Yang B et al. (2007) Derepression of microRNA-mediated protein translation inhibition by apolipoprotein b mRNAediting enzyme catalytic polypeptide-like 3g (APOBEC3G): And its family members. J Biol Chem 282:33632-33640.
    • (2007) J Biol Chem , vol.282 , pp. 33632-33640
    • Huang, J.1    Liang, Z.2    Yang, B.3
  • 59
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNAinterference enzyme dicer in the maturation of the let-7 small temporal RNA
    • Hutvágner G, McLachlan J, Pasquinelli AE et al. (2001) A cellular function for the RNAinterference enzyme dicer in the maturation of the let-7 small temporal RNA. Science 293:834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvágner, G.1    McLachlan, J.2    Pasquinelli, A.E.3
  • 60
    • 33846699083 scopus 로고    scopus 로고
    • A hexanucleotide element directs microRNA nuclear import
    • Hwang HW, Wentzel EA, Mendell JT (2007) A hexanucleotide element directs microRNA nuclear import. Science 315:97-100.
    • (2007) Science , vol.315 , pp. 97-100
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 61
    • 52949108889 scopus 로고    scopus 로고
    • First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome
    • Kapeller J, Houghton LA, Mönnikes H et al. (2008) First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor type 3E gene with diarrhea predominant irritable bowel syndrome. Hum Mol Genet 17:2967-2977.
    • (2008) Hum Mol Genet , vol.17 , pp. 2967-2977
    • Kapeller, J.1    Houghton, L.A.2    Mönnikes, H.3
  • 62
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • Karube Y, Tanaka H, Osada H et al. (2005) Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci 96:111-115.
    • (2005) Cancer Sci , vol.96 , pp. 111-115
    • Karube, Y.1    Tanaka, H.2    Osada, H.3
  • 63
    • 38349118916 scopus 로고    scopus 로고
    • RNA-binding protein Dnd1 inhibits microRNA access to target mRNA
    • Kedde M, Strasser MJ, Boldajipour B et al. (2007) RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 131:1273-1286.
    • (2007) Cell , vol.131 , pp. 1273-1286
    • Kedde, M.1    Strasser, M.J.2    Boldajipour, B.3
  • 64
    • 45549089973 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits the Epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma
    • Kefas B, Godlewski J, Comeau L et al. (2008) microRNA-7 inhibits the Epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68:3566- 3572.
    • (2008) Cancer Res , vol.68 , pp. 3566-3572
    • Kefas, B.1    Godlewski, J.2    Comeau, L.3
  • 65
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova A, Reynolds A, Jayasena SD (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell 115:209-216.
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 66
    • 34250017082 scopus 로고    scopus 로고
    • An mRNA m7G cap binding-like motif within human Ago2 represses translation
    • Kiriakidou M, Tan GS, Lamprinaki S et al. (2007) An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell 129:1141-1151.
    • (2007) Cell , vol.129 , pp. 1141-1151
    • Kiriakidou, M.1    Tan, G.S.2    Lamprinaki, S.3
  • 67
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki K, Imoto I, Mogi S et al. (2008) Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 68:2094-2105.
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3
  • 68
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky AM, King KS, Donahue CP et al. (2003) A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9:1274-1281.
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3
  • 69
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with'antagomirs'
    • Krützfeldt J, Rajewsky N, Braich R et al. (2005) Silencing of microRNAs in vivo with'antagomirs'. Nature 438:685-689.
    • (2005) Nature , vol.438 , pp. 685-689
    • Krützfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 70
    • 34250679405 scopus 로고    scopus 로고
    • Specificity duplex degradation and subcellular localization of antagomirs
    • Krützfeldt J, Kuwajima S, Braich R et al. (2007) Specificity duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res 35:2885-2892.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2885-2892
    • Krützfeldt, J.1    Kuwajima, S.2    Braich, R.3
  • 72
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar MS, Lu J, Mercer KL et al. (2007) Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet 39:673-677.
    • (2007) Nat Genet , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3
  • 73
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W et al. (2001) Identification of novel genes coding for small expressed RNAs. Science 294:853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3
  • 74
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129:1401-1414.
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 75
    • 58149233779 scopus 로고    scopus 로고
    • Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes
    • Lau P, Verrier JD, Nielsen JA et al. (2008) Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci 28:11720-11730.
    • (2008) J Neurosci , vol.28 , pp. 11720-11730
    • Lau, P.1    Verrier, J.D.2    Nielsen, J.A.3
  • 76
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(kip1): Tumor suppressor by mir- 221 and mir-222 promotes cancer cell proliferation
    • Le Sage C, Nagel R, Egan DA et al. (2007) Regulation of the p27(kip1): Tumor suppressor by mir- 221 and mir-222 promotes cancer cell proliferation. EMBO J 26:3699-3708.
    • (2007) EMBO J , vol.26 , pp. 3699-3708
    • Le Sage, C.1    Nagel, R.2    Egan, D.A.3
  • 77
    • 66149138833 scopus 로고    scopus 로고
    • MicroRNAs in cancer
    • Epub ahead of print
    • Lee YS, Dutta A (2009) MicroRNAs in cancer. Annu Rev Pathol 4: [Epub ahead of print].
    • (2009) Annu Rev Pathol , vol.4
    • Lee, Y.S.1    Dutta, A.2
  • 78
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 79
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee Y, Jeon K, Lee JT et al. (2002) MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J 21:4663-4670.
    • (2002) EMBO J , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3
  • 80
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNAse III Drosha initiates microRNA processing
    • Lee Y, Ahn C, Han J et al. (2003) The nuclear RNAse III Drosha initiates microRNA processing. Nature 425:415-419.
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 81
    • 2142708114 scopus 로고    scopus 로고
    • A short history of a short RNA
    • 1 p following S96
    • Lee R, Feinbaum R, Ambros V (2004) A short history of a short RNA. Cell 116:S89-S92; 1 p following S96.
    • (2004) Cell , vol.116 , pp. S89-S92
    • Lee, R.1    Feinbaum, R.2    Ambros, V.3
  • 82
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing often flanked by adenosines indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing often flanked by adenosines indicates that thousands of human genes are microRNA targets. Cell 120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 83
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P et al. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3
  • 84
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • Liu J, Valencia-Sanchez MA, Hannon GJ et al. (2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol 7:719-723.
    • (2005) Nat Cell Biol , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3
  • 85
    • 37349040713 scopus 로고    scopus 로고
    • Expression profiling of microRNA using oligo DNA arrays
    • Liu CG, Spizzo R, Calin GA et al. (2008) Expression profiling of microRNA using oligo DNA arrays. Methods 44:22-30.
    • (2008) Methods , vol.44 , pp. 22-30
    • Liu, C.G.1    Spizzo, R.2    Calin, G.A.3
  • 86
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435:834-838.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 87
    • 33846213881 scopus 로고    scopus 로고
    • Aberrant transcriptional regulation of the MLL fusion partner EEN by AML1-ETO and its implication in leukemogenesis
    • Ma LH, Liu H, Xiong H et al. (2007) Aberrant transcriptional regulation of the MLL fusion partner EEN by AML1-ETO and its implication in leukemogenesis. Blood 109:769-777.
    • (2007) Blood , vol.109 , pp. 769-777
    • Ma, L.H.1    Liu, H.2    Xiong, H.3
  • 88
    • 34547212309 scopus 로고    scopus 로고
    • The microRNA mir-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev EV, Zhang J, Carrasco MA et al. (2007) The microRNA mir-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 27:435-448.
    • (2007) Mol Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3
  • 89
    • 29144431656 scopus 로고    scopus 로고
    • A human atpindependent Risc assembly machine fueled by premiRNA
    • Maniataki E, Mourelatos Z (2005) A human atpindependent Risc assembly machine fueled by premiRNA. Genes Dev 19:2979-2990.
    • (2005) Genes Dev , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 90
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and HMGA2 enhances oncogenic transformation
    • Mayr C, Hemann MT, Bartel DP (2007) Disrupting the pairing between let-7 and HMGA2 enhances oncogenic transformation. Science 315:1576-1579.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 91
    • 33846053464 scopus 로고    scopus 로고
    • MirGen: A database for the study of animal microRNA genomic organization and function
    • Database issue
    • Megraw M, Sethupathy P, Corda B et al. (2007) MirGen: A database for the study of animal microRNA genomic organization and function. Nucleic Acids Res 35(Database issue): D149-D155.
    • (2007) Nucleic Acids Res , vol.35 , pp. D149-D155
    • Megraw, M.1    Sethupathy, P.2    Corda, B.3
  • 92
    • 3242736704 scopus 로고    scopus 로고
    • Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
    • Meister G, Landthaler M, Patkaniowska A et al. (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 15:185-197.
    • (2004) Mol Cell , vol.15 , pp. 185-197
    • Meister, G.1    Landthaler, M.2    Patkaniowska, A.3
  • 93
    • 57149110022 scopus 로고    scopus 로고
    • High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
    • Mestdagh P, Feys T, Bernard N et al. (2008) High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA. Nucleic Acids Res 36:e143.
    • (2008) Nucleic Acids Res , vol.36 , pp. e143
    • Mestdagh, P.1    Feys, T.2    Bernard, N.3
  • 94
    • 0142120587 scopus 로고    scopus 로고
    • Reduced accumulation of specific microRNAs in colorectal neoplasia
    • Michael MZ, Connor SMO, van Holst Pellekaan NG et al. (2003) Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 1:882-891.
    • (2003) Mol Cancer Res , vol.1 , pp. 882-891
    • Michael, M.Z.1    Connor, S.M.O.2    Van Holst, P.N.G.3
  • 95
    • 34548059198 scopus 로고    scopus 로고
    • A mir-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance
    • Mishra PJ, Humeniuk R, Mishra PJ et al. (2007) A mir-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci USA 104:13513-13518.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13513-13518
    • Mishra, P.J.1    Humeniuk, R.2    Mishra, P.J.3
  • 96
    • 5344273958 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in the developing mammalian brain
    • Miska EA, Alvarez-Saavedra E, Townsend M et al. (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol 5:R68.
    • (2004) Genome Biol , vol.5 , pp. R68
    • Miska, E.A.1    Alvarez-Saavedra, E.2    Townsend, M.3
  • 97
    • 0037087780 scopus 로고    scopus 로고
    • MiRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
    • Mourelatos Z, Dostie J, Paushkin S et al. (2002) MiRNPs: A novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev 16:720-728.
    • (2002) Genes Dev , vol.16 , pp. 720-728
    • Mourelatos, Z.1    Dostie, J.2    Paushkin, S.3
  • 98
    • 0001359591 scopus 로고
    • Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans
    • Napoli C, Lemieux C, Jorgensen R (1990) Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes in trans. Plant Cell 2:279-289.
    • (1990) Plant Cell , vol.2 , pp. 279-289
    • Napoli, C.1    Lemieux, C.2    Jorgensen, R.3
  • 99
    • 67349225999 scopus 로고    scopus 로고
    • Mir-92b and mir-9/9∗ are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors
    • Epub ahead of print
    • Nass D, Rosenwald S, Meiri E et al. (2008) Mir-92b and mir-9/9∗ are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors. Brain Pathol [Epub ahead of print].
    • (2008) Brain Pathol
    • Nass, D.1    Rosenwald, S.2    Meiri, E.3
  • 100
    • 13944283031 scopus 로고    scopus 로고
    • Microarray-based high-throughput gene expression profiling of microRNAs
    • Nelson PT, Baldwin DA, Scearce LM et al. (2004) Microarray-based high-throughput gene expression profiling of microRNAs. Nat Methods 1:155-161.
    • (2004) Nat Methods , vol.1 , pp. 155-161
    • Nelson, P.T.1    Baldwin, D.A.2    Scearce, L.M.3
  • 101
    • 31044455031 scopus 로고    scopus 로고
    • RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain
    • Nelson PT, Baldwin DA, Kloosterman WPN et al. (2006) RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA 12:187-191.
    • (2006) RNA , vol.12 , pp. 187-191
    • Nelson, P.T.1    Baldwin, D.A.2    Kloosterman, W.P.N.3
  • 102
    • 33745623128 scopus 로고    scopus 로고
    • Post-transcriptional regulation of micro- RNA expression
    • Obernosterer G, Leuschner PJF, Alenius M et al. (2006) Post-transcriptional regulation of micro- RNA expression. RNA 12:1161-1167.
    • (2006) RNA , vol.12 , pp. 1161-1167
    • Obernosterer, G.1    Leuschner, P.J.F.2    Alenius, M.3
  • 103
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell KA, Wentzel EA, Zeller KI et al. (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435:839-843.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3
  • 104
    • 34249810892 scopus 로고    scopus 로고
    • Argonaute proteins: Mediators of RNA silencing
    • Peters L, Meister G (2007) Argonaute proteins: mediators of RNA silencing. Mol Cell 26:611-623.
    • (2007) Mol Cell , vol.26 , pp. 611-623
    • Peters, L.1    Meister, G.2
  • 105
    • 32444436121 scopus 로고    scopus 로고
    • Short RNAs repress translation after initiation in mammalian cells
    • Petersen CP, Bordeleau ME, Pelletier J et al. (2006) Short RNAs repress translation after initiation in mammalian cells. Mol Cell 21:533-542.
    • (2006) Mol Cell , vol.21 , pp. 533-542
    • Petersen, C.P.1    Bordeleau, M.E.2    Pelletier, J.3
  • 106
    • 46349109152 scopus 로고    scopus 로고
    • Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
    • Pierson J, Hostager B, Fan R et al. (2008) Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J Neurooncol 90:1-7.
    • (2008) J Neurooncol , vol.90 , pp. 1-7
    • Pierson, J.1    Hostager, B.2    Fan, R.3
  • 107
    • 4644310115 scopus 로고    scopus 로고
    • Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
    • Pillai RS, Artus CG, Filipowicz W (2004) Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA 10:1518-1525.
    • (2004) RNA , vol.10 , pp. 1518-1525
    • Pillai, R.S.1    Artus, C.G.2    Filipowicz, W.3
  • 108
    • 24644480213 scopus 로고    scopus 로고
    • Inhibition of translational initiation by let-7 microRNA in human cells
    • Pillai RS, Bhattacharyya SN, Artus CG et al. (2005) Inhibition of translational initiation by let-7 microRNA in human cells. Science 309:1573-1576.
    • (2005) Science , vol.309 , pp. 1573-1576
    • Pillai, R.S.1    Bhattacharyya, S.N.2    Artus, C.G.3
  • 109
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • Reinhart BJ, Slack FJ, Basson M et al. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403:901-906.
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3
  • 110
    • 0037162702 scopus 로고    scopus 로고
    • Prediction of plant microRNA targets
    • Rhoades MW, Reinhart BJ, Lim LP et al. (2002) Prediction of plant microRNA targets. Cell 110:513-520.
    • (2002) Cell , vol.110 , pp. 513-520
    • Rhoades, M.W.1    Reinhart, B.J.2    Lim, L.P.3
  • 111
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez A, Griffiths-Jones S, Ashurst JL et al. (2004) Identification of mammalian microRNA host genes and transcription units. Genome Res 14:1902-1910.
    • (2004) Genome Res , vol.14 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3
  • 112
    • 0026441194 scopus 로고
    • Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano N, Macino G (1992) Quelling: Transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol Microbiol 6:3343-3353.
    • (1992) Mol Microbiol , vol.6 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 113
    • 33744805399 scopus 로고    scopus 로고
    • Specific activation of microRNA-127 with downregulation of the proto-oncogene Bcl6 by chromatin-modifying drugs in human cancer cells
    • Saito Y, Liang G, Egger G et al. (2006) Specific activation of microRNA-127 with downregulation of the proto-oncogene Bcl6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9:435-443.
    • (2006) Cancer Cell , vol.9 , pp. 435-443
    • Saito, Y.1    Liang, G.2    Egger, G.3
  • 114
    • 34249696957 scopus 로고    scopus 로고
    • Identification of cellular genes targeted by KSHV-encoded microRNAs
    • Samols MA, Skalsky RL, Maldonado AM et al. (2007) Identification of cellular genes targeted by KSHV-encoded microRNAs. PLoS Pathog 3:e65.
    • (2007) PLoS Pathog , vol.3 , pp. e65
    • Samols, M.A.1    Skalsky, R.L.2    Maldonado, A.M.3
  • 115
    • 38049066025 scopus 로고    scopus 로고
    • Lentivirus-mediated antagomir expression for specific inhibition of miRNA function
    • Scherr M, Venturini L, Battmer K et al. (2007) Lentivirus-mediated antagomir expression for specific inhibition of miRNA function. Nucleic Acids Res 35:e149.
    • (2007) Nucleic Acids Res , vol.35 , pp. e149
    • Scherr, M.1    Venturini, L.2    Battmer, K.3
  • 116
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • Schwarz DS, Hutvágner G, Du T et al. (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell 115:199-208.
    • (2003) Cell , vol.115 , pp. 199-208
    • Schwarz, D.S.1    Hutvágner, G.2    Du, T.3
  • 117
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere LF, Freemantle S, Pitha-Rowe I et al. (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5:R13.
    • (2004) Genome Biol , vol.5 , pp. R13
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3
  • 118
    • 44349101865 scopus 로고    scopus 로고
    • Mir-q: A novel quantitative RTPCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample
    • Sharbati-Tehrani S, Kutz-Lohroff B, Bergbauer R et al. (2008) Mir-q: A novel quantitative RTPCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample. BMC Mol Biol 9:34.
    • (2008) BMC Mol Biol , vol.9 , pp. 34
    • Sharbati-Tehrani, S.1    Kutz-Lohroff, B.2    Bergbauer, R.3
  • 119
    • 53049107572 scopus 로고    scopus 로고
    • Hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells
    • Shi L, Cheng Z, Zhang J et al. (2008) Hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res 1236C:185-193.
    • (2008) Brain Res , vol.1236 C , pp. 185-193
    • Shi, L.1    Cheng, Z.2    Zhang, J.3
  • 120
    • 48949116262 scopus 로고    scopus 로고
    • Mir-124 and mir-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
    • Silber J, Lim DA, Petritsch C et al. (2008) Mir-124 and mir-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 6:14.
    • (2008) BMC Med , vol.6 , pp. 14
    • Silber, J.1    Lim, D.A.2    Petritsch, C.3
  • 121
    • 24944560377 scopus 로고    scopus 로고
    • A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
    • Stegmeier F, Hu G, Rickles RJ et al. (2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc Natl Acad Sci USA 102:13212-13217.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13212-13217
    • Stegmeier, F.1    Hu, G.2    Rickles, R.J.3
  • 122
    • 34047267329 scopus 로고    scopus 로고
    • An e2f/mir-20a autoregulatory feedback loop
    • Sylvestre Y, Guire VD, Querido E et al. (2007) An e2f/mir-20a autoregulatory feedback loop. J Biol Chem 282:2135-2143.
    • (2007) J Biol Chem , vol.282 , pp. 2135-2143
    • Sylvestre, Y.1    Guire, V.D.2    Querido, E.3
  • 123
    • 34248200155 scopus 로고    scopus 로고
    • MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
    • Szafranska AE, Davison TS, John J et al. (2007) MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 26:4442-4452.
    • (2007) Oncogene , vol.26 , pp. 4442-4452
    • Szafranska, A.E.1    Davison, T.S.2    John, J.3
  • 124
    • 33750246178 scopus 로고    scopus 로고
    • Mouse microRNA profiles determined with a new and sensitive cloning method
    • Takada S, Berezikov E, Yamashita Y et al. (2006) Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res 34:e115.
    • (2006) Nucleic Acids Res , vol.34 , pp. e115
    • Takada, S.1    Berezikov, E.2    Yamashita, Y.3
  • 125
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 micro- RNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa J, Konishi H, Yanagisawa K et al. (2004) Reduced expression of the let-7 micro- RNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64:3753-3756.
    • (2004) Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3
  • 126
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: Mir-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V, Jung P, Verdoodt B et al. (2007) Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: mir-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6:1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3
  • 127
    • 33747334621 scopus 로고    scopus 로고
    • Extensive post-transcriptional regulation of microRNAs and its implications for cancer
    • Thomson JM, Newman M, Parker JS et al. (2006) Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 20:2202-2207.
    • (2006) Genes Dev , vol.20 , pp. 2202-2207
    • Thomson, J.M.1    Newman, M.2    Parker, J.S.3
  • 129
    • 14644393684 scopus 로고    scopus 로고
    • Perspective: Machines for RNAi
    • Tomari Y, Zamore PD (2005) Perspective: machines for RNAi. Genes Dev 19:517-529.
    • (2005) Genes Dev , vol.19 , pp. 517-529
    • Tomari, Y.1    Zamore, P.D.2
  • 130
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekström K, Bossios A et al. (2007) Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 9:654-659.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3
  • 131
    • 0025405838 scopus 로고
    • Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression
    • van der Krol AR, Mur LA, Beld M et al. (1990) Flavonoid genes in petunia: Addition of a limited number of gene copies may lead to a suppression of gene expression. Plant Cell 2:291-299.
    • (1990) Plant Cell , vol.2 , pp. 291-299
    • Van Der Krol, A.R.1    Mur, L.A.2    Beld, M.3
  • 132
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318:1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 133
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin- 14 by lin-4 mediates temporal pattern formation in C. Elegans
    • Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin- 14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 134
    • 54949103214 scopus 로고    scopus 로고
    • Mir-296 regulates growth factor receptor overexpression in angiogenic endothelial cells
    • Würdinger T, Tannous BA, Saydam O et al. (2008) Mir-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell 14:382-393.
    • (2008) Cancer Cell , vol.14 , pp. 382-393
    • Würdinger, T.1    Tannous, B.A.2    Saydam, O.3
  • 135
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta S, Shih IH, Bartel DP (2004) MicroRNA-directed cleavage of HOXB8 mRNA. Science 304:594-596.
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 136
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG et al. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3
  • 137
    • 38549120730 scopus 로고    scopus 로고
    • Profiling microRNA expression with microarrays
    • Yin JQ, Zhao RC, Morris KV (2008) Profiling microRNA expression with microarrays. Trends Biotechnol 26:70-76.
    • (2008) Trends Biotechnol , vol.26 , pp. 70-76
    • Yin, J.Q.1    Zhao, R.C.2    Morris, K.V.3
  • 138
    • 58049202164 scopus 로고    scopus 로고
    • MicroRNA-184 antagonizes microRNA-205 to maintain Ship2 levels in epithelia
    • Yu J, Ryan DG, Getsios S et al. (2008) MicroRNA-184 antagonizes microRNA-205 to maintain Ship2 levels in epithelia. Proc Natl Acad Sci USA 105:19300-19305.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19300-19305
    • Yu, J.1    Ryan, D.G.2    Getsios, S.3
  • 139
    • 33745168962 scopus 로고    scopus 로고
    • MicroRNAs exhibit high frequency genomic alterations in human cancer
    • Zhang L, Huang J, Yang N et al. (2006) MicroRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci USA 103:9136-9141.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9136-9141
    • Zhang, L.1    Huang, J.2    Yang, N.3
  • 140
    • 45849136737 scopus 로고    scopus 로고
    • DNA damage induced S phase arrest in human breast cancer depends on Chk1 but G2 arrest can occur independently of Chk1 Chk2 or MAPKAPK2
    • Zhang WH, Poh A, Fanous A et al. (2008) DNA damage induced S phase arrest in human breast cancer depends on Chk1 but G2 arrest can occur independently of Chk1 Chk2 or MAPKAPK2. Cell Cycle 7:1668-1677.
    • (2008) Cell Cycle , vol.7 , pp. 1668-1677
    • Zhang, W.H.1    Poh, A.2    Fanous, A.3
  • 141
    • 57849155254 scopus 로고    scopus 로고
    • MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a
    • Zhang Y, Chao T, Li R et al. (2009) MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a. J Mol Med 87:43-51.
    • (2009) J Mol Med , vol.87 , pp. 43-51
    • Zhang, Y.1    Chao, T.2    Li, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.