-
1
-
-
2942520981
-
Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells
-
Nimer SD, Moore MA. Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells. Oncogene. 2004;23:4249-4254.
-
(2004)
Oncogene
, vol.23
, pp. 4249-4254
-
-
Nimer, S.D.1
Moore, M.A.2
-
2
-
-
2942516037
-
The 8;21 translocation in leukemogenesis
-
Peterson LF, Zhang DE. The 8;21 translocation in leukemogenesis. Oncogene. 2004;23:4255-4262.
-
(2004)
Oncogene
, vol.23
, pp. 4255-4262
-
-
Peterson, L.F.1
Zhang, D.E.2
-
3
-
-
0027383818
-
Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: The runt homology domain is required for DNA binding and protein-protein interactions
-
Meyers S, Downing JR, Hiebert SW. Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions. Mol Cell Biol. 1993;13:6336-6345.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6336-6345
-
-
Meyers, S.1
Downing, J.R.2
Hiebert, S.W.3
-
4
-
-
0030445949
-
The AML1/ETO fusion protein activates transcription of BCL-2
-
Klampfer L, Zhang J, Zelenetz AO, Uchida H, Nimer SD. The AML1/ETO fusion protein activates transcription of BCL-2. Proc Natl Acad Sci U S A. 1996;93:14059-14064.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 14059-14064
-
-
Klampfer, L.1
Zhang, J.2
Zelenetz, A.O.3
Uchida, H.4
Nimer, S.D.5
-
5
-
-
0034661487
-
Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: Overexpression of the TIS11b (ERF-1, cMG1) gene induces myeloid cell proliferation in response to G-CSF
-
Shimada H, Ichikawa H, Nakamura S, et al. Analysis of genes under the downstream control of the t(8;21) fusion protein AML1-MTG8: overexpression of the TIS11b (ERF-1, cMG1) gene induces myeloid cell proliferation in response to G-CSF. Blood. 2000;96:655-663.
-
(2000)
Blood
, vol.96
, pp. 655-663
-
-
Shimada, H.1
Ichikawa, H.2
Nakamura, S.3
-
6
-
-
0034234513
-
AML1-MTG8 leukemic protein induces the expression of granulocyte colony-stimulating factor (G-CSF) receptor through the up-regulation of CCAAT/enhancer binding protein epsilon
-
Shimizu K, Kitabayashi I, Kamada N, et al. AML1-MTG8 leukemic protein induces the expression of granulocyte colony-stimulating factor (G-CSF) receptor through the up-regulation of CCAAT/enhancer binding protein epsilon. Blood. 2000;96:288-296.
-
(2000)
Blood
, vol.96
, pp. 288-296
-
-
Shimizu, K.1
Kitabayashi, I.2
Kamada, N.3
-
7
-
-
17044413548
-
The versatile mixed lineage leukemia gene MLL and its many associations in leukaemogenesis
-
Daser A, Rabbitts TH. The versatile mixed lineage leukemia gene MLL and its many associations in leukaemogenesis. Semin Cancer Biol. 2005;15:175-188.
-
(2005)
Semin Cancer Biol
, vol.15
, pp. 175-188
-
-
Daser, A.1
Rabbitts, T.H.2
-
8
-
-
0035839952
-
Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
-
Ayton PM, Cleary ML. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene. 2001;20:5695-5707.
-
(2001)
Oncogene
, vol.20
, pp. 5695-5707
-
-
Ayton, P.M.1
Cleary, M.L.2
-
10
-
-
33646161959
-
The MLL recombinome of acute leukemias
-
Meyer C, Schneider B, Jakob S, et al. The MLL recombinome of acute leukemias. Leukemia. 2006;20:777-784.
-
(2006)
Leukemia
, vol.20
, pp. 777-784
-
-
Meyer, C.1
Schneider, B.2
Jakob, S.3
-
11
-
-
15844394270
-
An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
-
Corral J, Lavenir I, Impey H, et al. An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell. 1996;85:853-861.
-
(1996)
Cell
, vol.85
, pp. 853-861
-
-
Corral, J.1
Lavenir, I.2
Impey, H.3
-
12
-
-
0000778884
-
EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia
-
So CW, Caldas C, Liu MM, et al. EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia. Proc Natl Acad Sci U S A. 1997;94:2563-2568.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2563-2568
-
-
So, C.W.1
Caldas, C.2
Liu, M.M.3
-
13
-
-
2442720107
-
Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein
-
Liu H, Chen B, Xiong H, et al. Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein. Oncogene. 2004;23:3385-3394.
-
(2004)
Oncogene
, vol.23
, pp. 3385-3394
-
-
Liu, H.1
Chen, B.2
Xiong, H.3
-
14
-
-
0035798535
-
Differential expression of endophilin 1 and 2 dimers at central nervous system synapses
-
Ringstad N, Nemoto Y, De CP. Differential expression of endophilin 1 and 2 dimers at central nervous system synapses. J Biol Chem. 2001;276:40424-40430.
-
(2001)
J Biol Chem
, vol.276
, pp. 40424-40430
-
-
Ringstad, N.1
Nemoto, Y.2
De, C.P.3
-
15
-
-
0030739938
-
The SH3p4/Sh3p8/SH3p13 protein family: Binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain
-
Ringstad N, Nemoto Y, De CP. The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain. Proc Natl Acad Sci U S A. 1997;94:8569-8574.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 8569-8574
-
-
Ringstad, N.1
Nemoto, Y.2
De, C.P.3
-
16
-
-
0034119048
-
The interaction between EEN and Abi-1, 2 MLL fusion partners, and synaptojanin and dynamin: Implications for leukaemogenesis
-
So CW, So CK, Cheung N, et al The interaction between EEN and Abi-1, 2 MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis. Leukemia. 2000;14:594-601.
-
(2000)
Leukemia
, vol.14
, pp. 594-601
-
-
So, C.W.1
So, C.K.2
Cheung, N.3
-
17
-
-
0033607141
-
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor
-
Tang Y, Hu LA, Miller WE, et al. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. Proc Natl Acad Sci U S A. 1999;96:12559-12564.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 12559-12564
-
-
Tang, Y.1
Hu, L.A.2
Miller, W.E.3
-
18
-
-
0141987891
-
2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis
-
2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis. Cell. 2003;115:37-48.
-
(2003)
Cell
, vol.115
, pp. 37-48
-
-
Chen, Y.1
Deng, L.2
Maeno-Hikichi, Y.3
-
19
-
-
21644464655
-
Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain
-
Lua BL, Low BC. Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain. J Cell Sci. 2005;118:2707-2721.
-
(2005)
J Cell Sci
, vol.118
, pp. 2707-2721
-
-
Lua, B.L.1
Low, B.C.2
-
20
-
-
0842307321
-
Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein
-
Yam JW, Jin DY, So CW, Chan LC. Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. Blood. 2004;103:1445-1453.
-
(2004)
Blood
, vol.103
, pp. 1445-1453
-
-
Yam, J.W.1
Jin, D.Y.2
So, C.W.3
Chan, L.C.4
-
21
-
-
0031955518
-
Base-calling of automated sequencer traces using phred, I: Accuracy assessment
-
Ewing B, Hillier L, Wendl MC, Green P. Base-calling of automated sequencer traces using phred, I: accuracy assessment. Genome Res. 1998;8:175-185.
-
(1998)
Genome Res
, vol.8
, pp. 175-185
-
-
Ewing, B.1
Hillier, L.2
Wendl, M.C.3
Green, P.4
-
22
-
-
0028786125
-
Functional domains of the t(8;21) fusion protein, AML-1/ETO
-
Lenny N, Meyers S, Hiebert SW. Functional domains of the t(8;21) fusion protein, AML-1/ETO. Oncogene. 1995;11:1761-1769.
-
(1995)
Oncogene
, vol.11
, pp. 1761-1769
-
-
Lenny, N.1
Meyers, S.2
Hiebert, S.W.3
-
23
-
-
0031020428
-
Diverse genetic regulatory motifs required for murine adenosine deaminase gene expression in the placenta
-
Shi D, Winston JH, Blackburn MR, et al. Diverse genetic regulatory motifs required for murine adenosine deaminase gene expression in the placenta. J Biol Chem. 1997;272:2334-2341.
-
(1997)
J Biol Chem
, vol.272
, pp. 2334-2341
-
-
Shi, D.1
Winston, J.H.2
Blackburn, M.R.3
-
24
-
-
0036024955
-
Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation
-
Weinmann AS, Farnham PJ. Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation. Methods. 2002;26:37-47.
-
(2002)
Methods
, vol.26
, pp. 37-47
-
-
Weinmann, A.S.1
Farnham, P.J.2
-
25
-
-
0842329808
-
Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice
-
Cuenco GM, Ren R. Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice. Oncogene. 2004;23:569-579.
-
(2004)
Oncogene
, vol.23
, pp. 569-579
-
-
Cuenco, G.M.1
Ren, R.2
-
26
-
-
0035925052
-
Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene
-
Dong H, Lin W, Zhang CK, et al. Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene. Gene. 2001;264:187-196.
-
(2001)
Gene
, vol.264
, pp. 187-196
-
-
Dong, H.1
Lin, W.2
Zhang, C.K.3
-
27
-
-
13244279499
-
The Kasumi-1 cell line: A t(8;21)-kit mutant model for acute myeloid leukemia
-
Larizza L, Magnani I, Beghini A. The Kasumi-1 cell line: a t(8;21)-kit mutant model for acute myeloid leukemia. Leuk Lymphoma. 2005;46:247-255.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 247-255
-
-
Larizza, L.1
Magnani, I.2
Beghini, A.3
-
28
-
-
0025817842
-
Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation
-
Asou H, Tashiro S, Hamamoto K, et al. Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation. Blood. 1991;77:2031-2036.
-
(1991)
Blood
, vol.77
, pp. 2031-2036
-
-
Asou, H.1
Tashiro, S.2
Hamamoto, K.3
-
29
-
-
10944271468
-
Williams-Beuren syndrome critical region-5/non-T-cell activation linker: A novel target gene of AML1/ETO
-
Fliegauf M, Stock M, Berg T, Lubbert M. Williams-Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO. Oncogene. 2004;23:9070-9081.
-
(2004)
Oncogene
, vol.23
, pp. 9070-9081
-
-
Fliegauf, M.1
Stock, M.2
Berg, T.3
Lubbert, M.4
-
30
-
-
19944431253
-
AML1-ETO and C-KIT mutation/ overexpression in t(8;21) leukemia: Implication in stepwise leukemogenesis and response to Gleevec
-
Wang YY, Zhou GB, Yin T, et al. AML1-ETO and C-KIT mutation/ overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec. Proc Natl Acad Sci U S A. 2005;102:1104-1109.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1104-1109
-
-
Wang, Y.Y.1
Zhou, G.B.2
Yin, T.3
-
31
-
-
0029100157
-
Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia
-
Miyoshi H, Ohira M, Shimizu K, et al Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia. Nucleic Acids Res. 1995;23:2762-2769.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2762-2769
-
-
Miyoshi, H.1
Ohira, M.2
Shimizu, K.3
-
32
-
-
0025221436
-
Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter
-
Blake MC, Jambou RC, Swick AG, Kahn JW, Azizkhan JC. Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter. Mol Cell Biol. 1990;10:6632-6641.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 6632-6641
-
-
Blake, M.C.1
Jambou, R.C.2
Swick, A.G.3
Kahn, J.W.4
Azizkhan, J.C.5
-
33
-
-
0031579666
-
Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes
-
Smale ST. Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes. Biochim Biophys Acta. 1997;1351:73-88.
-
(1997)
Biochim Biophys Acta
, vol.1351
, pp. 73-88
-
-
Smale, S.T.1
-
34
-
-
0032866999
-
The Sp-family of transcription factors
-
Suske G. The Sp-family of transcription factors. Gene. 1999;238:291-300.
-
(1999)
Gene
, vol.238
, pp. 291-300
-
-
Suske, G.1
-
35
-
-
0033522234
-
The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1
-
Frank RC, Sun X, Berguido FJ, Jakubowiak A, Nimer SD. The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1. Oncogene. 1999;18:1701-1710.
-
(1999)
Oncogene
, vol.18
, pp. 1701-1710
-
-
Frank, R.C.1
Sun, X.2
Berguido, F.J.3
Jakubowiak, A.4
Nimer, S.D.5
-
36
-
-
0030791974
-
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
-
Lavau C, Szilvassy SJ, Slany R, Cleary ML. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J. 1997;16:4226-4237.
-
(1997)
EMBO J
, vol.16
, pp. 4226-4237
-
-
Lavau, C.1
Szilvassy, S.J.2
Slany, R.3
Cleary, M.L.4
-
39
-
-
6344248913
-
Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukemia
-
Cheung N, So CW, Yam JW, et al. Subcellular localization of EEN/endophilin A2, a fusion partner gene in leukemia. Biochem J. 2004;383:27-35.
-
(2004)
Biochem J
, vol.383
, pp. 27-35
-
-
Cheung, N.1
So, C.W.2
Yam, J.W.3
-
40
-
-
0029859199
-
Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis
-
Rhoades KL, Hetherington CJ, Rowley JD, et al. Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis. Proc Natl Acad Sci U S A. 1996;93:11895-11900.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 11895-11900
-
-
Rhoades, K.L.1
Hetherington, C.J.2
Rowley, J.D.3
-
41
-
-
0034548852
-
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein
-
Melnick A, Carlile GW, McConnell MJ, et al. AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood. 2000;96:3939-3947.
-
(2000)
Blood
, vol.96
, pp. 3939-3947
-
-
Melnick, A.1
Carlile, G.W.2
McConnell, M.J.3
-
42
-
-
0041335555
-
The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner
-
Elsasser A, Franzen M, Kohlmann A, et al. The fusion protein AML1-ETO in acute myeloid leukemia with translocation t(8;21) induces c-jun protein expression via the proximal AP-1 site of the c-jun promoter in an indirect, JNK-dependent manner. Oncogene. 2003;22:5646-5657.
-
(2003)
Oncogene
, vol.22
, pp. 5646-5657
-
-
Elsasser, A.1
Franzen, M.2
Kohlmann, A.3
-
43
-
-
0032934989
-
A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation
-
Liu LQ, Ilaria R Jr, Kingsley PD, et al. A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation. Mol Cell Biol. 1999;19:3029-3038.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3029-3038
-
-
Liu, L.Q.1
Ilaria Jr, R.2
Kingsley, P.D.3
-
45
-
-
0034941566
-
Dichotomy of AML1-ETO functions: Growth arrest versus block of differentiation
-
Burel SA, Harakawa N, Zhou L, et al. Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation. Mol Cell Biol. 2001;21:5577-5590.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5577-5590
-
-
Burel, S.A.1
Harakawa, N.2
Zhou, L.3
-
46
-
-
33746494493
-
Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: The role in AML1-ETO-induced growth arrest in leukemic cells
-
Li X, Xu YB, Wang Q, et al. Leukemogenic AML1-ETO fusion protein upregulates expression of connexin 43: the role in AML1-ETO-induced growth arrest in leukemic cells. J Cell Physiol. 2006;208:594-601.
-
(2006)
J Cell Physiol
, vol.208
, pp. 594-601
-
-
Li, X.1
Xu, Y.B.2
Wang, Q.3
-
47
-
-
0032828882
-
Early signaling pathways activated by c-Kit in hematopoietic cells
-
Linnekin D. Early signaling pathways activated by c-Kit in hematopoietic cells. Int J Biochem Cell Biol. 1999;31:1053-1074.
-
(1999)
Int J Biochem Cell Biol
, vol.31
, pp. 1053-1074
-
-
Linnekin, D.1
-
48
-
-
0028036596
-
Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide
-
Sakakura C, Yamaguchi-Iwai Y, Satake M, et al. Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide. Proc Natl Acad Sci U S A. 1994;91:11723-11727.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11723-11727
-
-
Sakakura, C.1
Yamaguchi-Iwai, Y.2
Satake, M.3
-
49
-
-
0028876993
-
Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21)
-
Matsushita H, Kobayashi H, Mori S, Kizaki M, Ikeda Y. Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21). Biochem Biophys Res Commun. 1995;215:431-437.
-
(1995)
Biochem Biophys Res Commun
, vol.215
, pp. 431-437
-
-
Matsushita, H.1
Kobayashi, H.2
Mori, S.3
Kizaki, M.4
Ikeda, Y.5
|