New concepts in calcium-sensing receptor pharmacology and signalling

British Journal of Pharmacology

Volumn 165, Issue 1, 2012, Pages 35-48

  Ward, Donald T ^a   Riccardi, Daniela ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

allosteric modulators; calcilytics; calcimimetics; cell signalling; Class C G protein coupled receptors; extracellular calcium; receptor phosphorylation

Indexed keywords

1 (3 METHOXYPHENYL) N (3 PHENYLPROPYL)ETHYLAMINE; 2 CHLORO 6 [3 [1,1 DIMETHYL 2 (2 NAPHTHYL)ETHYLAMINO] 2 HYDROXYPROPOXY]BENZONITRILE; AC 265347; BENZOTHIAZOLE DERIVATIVE; CALCIMIMETIC AGENT; CALCIUM ION; CALCIUM SENSING RECEPTOR; CALCIUM SENSING RECEPTOR MODULATOR; CALHEX 231; CALINDOL; CINACALCET; G PROTEIN COUPLED RECEPTOR; ION TRANSPORT AFFECTING AGENT; MITOGEN ACTIVATED PROTEIN KINASE; NPS 53574; PARATHYROID HORMONE; REAGENT; RONACALERET; SB 423557; SB 423652; TECALCET; UNCLASSIFIED DRUG;

BONE TISSUE; CALCIUM ABSORPTION; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; CONCENTRATION RESPONSE; CYTOSKELETON; DRUG ABSORPTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVATION; HUMAN; HYPERCALCEMIA; HYPERPARATHYROIDISM; HYPOCALCEMIA; HYPOPARATHYROIDISM; IN VIVO STUDY; KIDNEY TUBULE ABSORPTION; MORTALITY; NONHUMAN; OSTEOPOROSIS; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; REGULATORY MECHANISM; REVIEW; RISK REDUCTION; TISSUE SPECIFICITY; TRANSGENIC MOUSE; VASCULAR DISEASE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CALCIUM; GENE DELETION; HOMEOSTASIS; MICE; PARATHYROID HORMONE; RECEPTORS, CALCIUM-SENSING;

EID: 82955177013     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01511.x     Document Type: Review

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