Characterization of highly efficacious allosteric agonists of the human calcium-sensing receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 337, Issue 1, 2011, Pages 275-284

  Ma, Jian Nong ^a   Owens, Michelle ^a   Gustafsson, Magnus ^a   Jensen, Jacob ^a   Tabatabaei, Ali ^a   Schmelzer, Kara ^a   Olsson, Roger ^a   Burstein, Ethan S ^a  

^a ACADIA PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZOTHIAZOL 2 YL 1 (2,4 DIMETHYLPHENYL)ETHANOL; AC 265347; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALANINE; CALCIMIMETIC AGENT; CALCIUM ION; CALCIUM SENSING RECEPTOR; CALCIUM SENSING RECEPTOR AGONIST; CALINDOL; CINACALCET; GLUTAMIC ACID; ISOLEUCINE; ISOPROTEIN; MEMBRANE PROTEIN; PARATHYROID HORMONE; PHENYLALKYLAMINE; PHOSPHATIDYLINOSITOL; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT; RAT; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; ANIMALS; BENZOTHIAZOLES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALE; MICE; NIH 3T3 CELLS; PARATHYROID GLANDS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING;

EID: 79953008685     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.178194     Document Type: Article

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