SCOPUS 정보 검색 플랫폼

Journal of Pharmacology and Experimental Therapeutics

Volumn 299, Issue 1, 2001, Pages 323-331

Calcilytic compounds: Potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone

(10) Nemeth, Edward F a,c Delmar, Eric G a Heaton, William L a Miller, Michael A a Lambert, Lyssa D a Conklin, Rebecca L a Gowen, Maxine b Gleason, John G b Bhatnagar, Pradip K b Fox, John a

a NPS Pharmaceutical Inc (United States)

b GLAXOSMITHKLINE (United Kingdom)

c NPS Pharmaceuticals Incorporated (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3 METHOXYPHENYL) N (3 PHENYLPROPYL)ETHYLAMINE; 2 CHLORO 6 [3 [1,1 DIMETHYL 2 (2 NAPHTHYL)ETHYLAMINO] 2 HYDROXYPROPOXY]BENZONITRILE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM ION; PARATHYROID HORMONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MINERALIZATION; CALCIUM ANTAGONISM; CATTLE; CELL LINE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; PARATHYROID CELL; PARATHYROID HORMONE RELEASE; PRIORITY JOURNAL; RAT;

ANILINE COMPOUNDS; ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CATTLE; CELL LINE; EXTRACELLULAR SPACE; GTP-BINDING PROTEINS; HUMANS; MALE; NAPHTHALENES; PARATHYROID GLANDS; PARATHYROID HORMONE; RATS; RATS, SPRAGUE-DAWLEY; STIMULATION, CHEMICAL;

EID: 0034806606 PISSN: 00223565 EISSN: None Source Type: Journal
DOI: None Document Type: Article

Times cited : (222)

References (25)

1
- 0029052723
- The pharmacology of SCH 50911: A novel, orally-active GABA-B receptor antagonist
- (1995) J Pharmacol Exp Ther , vol.274 , pp. 1393-1398
- Bolser, D.C.¹ Blythin, D.J.² Chapman, R.W.³ Egan, R.W.⁴ Hey, J.A.⁵ Rizzo, C.⁶ Kuo, S.C.⁷ Kreutner, W.⁸

2
- 0035138842
- Extracellular calcium sensing and extracellular calcium signaling
- (2001) Physiol Rev , vol.81 , pp. 239-297
- Brown, E.M.¹ MacLeod, R.J.²

3
- 0027716654
- Anabolic actions of parathyroid hormone
- (1993) Endocr Rev , vol.14 , pp. 690-709
- Dempster, D.W.¹ Cosman, F.² Parisien, M.³ Shen, V.⁴ Lindsay, R.⁵

4
- 0027317601
- Human parathyroid hormone (1-34) and (1-84) increase the mechanical strength and thickness of cortical bone in rats
- (1995) J Bone Miner Res , vol.8 , pp. 1097-1101
- Ejersted, C.¹ Andreassen, T.T.² Oxlund, H.³ Jorgensen, P.H.⁴ Bak, B.⁵ Häggblad, J.⁶ Tørring, O.⁷ Nilsson, M.H.L.⁸

5
- 0032763887
- 2+ receptor in rats
- (1999) J Pharmacol Exp Ther , vol.290 , pp. 480-486
- Fox, J.¹ Lowe, S.H.² Conklin, R.L.³ Petty, B.A.⁴ Nemeth, E.F.⁵

6
- 0030869896
- Plasma levels of parathyroid hormone that induce anabolic effects in bone of ovariectomized rats can be achieved by stimulation of endogenous hormone secretion
- (1997) Bone , vol.21 , pp. 163-169
- Fox, J.¹ Miller, M.A.² Stroup, G.B.³ Nemeth, E.F.⁴ Miller, S.C.⁵

7
- 0032909761
- Effect of an intermittent weekly dose of human parathyroid hormone (1-34) on osteoporosis: A randomized double-masked prospective study using three dose levels
- (1999) Osteoporos Int , vol.9 , pp. 296-306
- Fujita, T.¹ Inoue, T.² Morii, H.³ Norimatsu, H.⁴ Orimo, H.⁵ Takahashi, H.E.⁶ Yamamoto, K.⁷ Fukunaga, M.⁸

8
- 0034123554
- 2+ receptor with a calcilytic compound induces PTH secretion and stimulates bone formation in osteopenic rats
- (2000) J Clin Invest , vol.105 , pp. 1595-1604
- Gowen, M.¹ Streup, G.B.² Dedds, P.A.³ James, I.E.⁴ Votta, B.J.⁵ Smith, B.R.⁶ Bhatnagar, P.K.⁷ Lago, A.M.⁸ Callahan, J.F.⁹ DelMar, E.G.¹⁰

9
- 0031024187
- A randomized controlled trial to compare the efficacy of cyclical parathyroid hormone versus cyclical parathyroid hormone and sequential calcitonin to improve bone mass in postmenopausal women with osteoporosis
- (1997) J Clin Endocrinol Metab , vol.82 , pp. 620-628
- Hodsman, A.B.¹ Fraher, L.J.² Watson, P.H.³ Ostbye, T.⁴ Stitt, L.W.⁵ Adachi, J.D.⁶ Taves, D.H.⁷ Drost, D.⁸

10
- 0027514232
- The effect of recombinant human (1-84) or synthetic human (1-34) parathyroid hormone on the skeleton of adult ovariectomized rats
- (1993) Endocrinology , vol.132 , pp. 1577-1584
- Kimmel, D.B.¹ Bozzato, R.P.² Kronis, K.A.³ Coble, T.⁴ Sindrey, D.⁵ Kwong, P.⁶ Recker, R.R.⁷

11
- 0032532062
- Parathyroid hormone treatment can reverse corticosteroid-induced osteoperosis
- (1998) J Clin Invest , vol.102 , pp. 1627-1633
- Lane, N.E.¹ Sanchez, S.² Modin, G.W.³ Genant, H.K.⁴ Pierini, E.⁵ Arnaud, C.D.⁶

12
- 0032469139
- Stimulation of calcitonin secretion by calcium receptor activators: Evaluation using a new, highly-sensitive homologous immunoradiometric assay for rat calcitonin
- (1998) Endocrine , vol.9 , pp. 293-301
- Lavigne, J.R.¹ Zahradnik, R.J.² Conklin, R.L.³ Lambert, L.D.⁴ Logan, M.A.⁵ Parihar, A.⁶ Fox, J.⁷

13
- 0029081977
- Response of femoral neck to estrogen depletion and parathyroid hormone in aged rats
- (1995) Bone , vol.16 , pp. 551-557
- Li, M.¹ Wronski, T.J.²

14
- 0027132484
- Subcutaneous administration of the amino-terminal fragment of human parathyroid hormone-(1-34): Kinetics and biochemical response in estrogenized osteoporotic patients
- (1993) J Clin Endocrinol Metab , vol.77 , pp. 1535-1539
- Lindsay, R.¹ Nieves, J.² Henneman, E.³ Shen, V.⁴ Cosman, F.⁵

15
- 0030804947
- Randomised controlled study of effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis
- (1997) Lancet , vol.350 , pp. 550-555
- Lindsay, R.¹ Nieves, J.² Formica, C.³ Henneman, E.⁴ Woelfert, L.⁵ Shen, V.⁶ Dempster, D.⁷ Cosman, F.⁸

16
- 0028245443
- PTH has a more pronounced effect on vertebral bone mass and biomechanical competence than antiresorptive agents (estrogen and bisphosphonate)-assessed in sexually mature, ovariectomized rats
- (1994) Bone , vol.15 , pp. 401-408
- Mosekilde, L.¹ Sogaard, C.H.² McOsker, J.E.³ Wronski, T.J.⁴

17
- 0002880915
- Calcium receptors as novel drug targets
- (Bilezekian JP, Raisz LG, and Redan G eds), Academic Press, San Diego
- (1996) Principles of Bone Biology , pp. 1019-1035
- Nemeth, E.F.¹

18
- 0033029793
- Calcimimetic compounds: A direct approach to controlling plasma levels of parathyroid hormone in hyperparathyroidism
- (1999) Trends Endocrinol Metab , vol.10 , pp. 66-71
- Nemeth, E.F.¹ Fox, J.²

19
- 0023654485
- 2+ in bovine parathyroid cells evoked by extracellular divalent cations. Evidence for a cell surface calcium receptor
- (1987) J Biol Chem , vol.262 , pp. 5188-5196
- Nemeth, E.F.¹ Scarpa, A.²

20
- 0032584086
- Calcimimetics with potent and selective activity on the parathyroid calcium receptor
- (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4040-4045
- Nemeth, E.F.¹ Steffey, M.E.² Hammerland, L.G.³ Hung, B.C.P.⁴ Van Wagenen, B.C.⁵ DelMar, E.G.⁶ Balandrin, M.F.⁷

21
- 0027272509
- Cytosolic calcium homeostasis in bovine parathyroid cells and its modulation by protein kinase C
- (1993) J Physiol (Lond) , vol.468 , pp. 141-162
- Racke, F.K.¹ Nemeth, E.F.²

22
- 0030113479
- PTH: A future role in the management of osteoporosis?
- (1996) J Bone Miner Res , vol.11 , pp. 440-445
- Reeve, J.¹

23
- 0034458020
- Enhancement of bone mass in osteoporotic women with parathyroid hormone followed by alendronate
- (2000) J Clin Endocrinol Metab , vol.85 , pp. 2129-2134
- Rittmaster, R.S.¹ Bolognese, M.² Ettinger, M.P.³ Hanley, D.A.⁴ Hodsman, A.B.⁵ Kendler, D.L.⁶ Rosen, C.J.⁷

24
- 0028913684
- Increased bone mineral density after parathyroidectomy in primary hyperparathyroidism
- (1995) J Clin Endocrinol Metab , vol.80 , pp. 729-734
- Silverberg, S.J.¹ Gartenberg, F.² Jacobs, T.P.³ Shane, E.⁴ Siris, E.⁵ Staron, R.B.⁶ McMahon, D.J.⁷ Bilezekian, J.P.⁸

25
- 0003313368
- In vitro pharmacological characterization of NPS 2390: A highly potent and selective noncompetitive antagonist of Group 1 metabotropic glutamate receptors
- 1998 November 7-12; Los Angeles, CA. Society for Neuroscience, Washington, DC
- (1998) th Annual Meeting of the Society for Neuroscience , vol.24 , Issue.PART 1 , pp. 576
- Van Wagenen, B.C.¹ Artman, L.D.² Hammerland, L.G.³ Hung, B.C.P.⁴ Johnston, J.⁵ Krapcho, K.⁶ Levinthal, C.⁷ Logan, M.A.⁸ Moe, S.T.⁹ Mueller, A.L.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.