Protein kinase C-mediated phosphorylation of the calcium-sensing receptor is stimulated by receptor activation and attenuated by calyculin-sensitive phosphatase activity

Journal of Biological Chemistry

Volumn 282, Issue 20, 2007, Pages 15048-15056

  Davies, Sarah L ^a   Ozawa, Ai ^a   McCormick, Wanda D ^a   Dvorak, Melita M ^a,b   Ward, Donald T ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM SENSING RECEPTOR (CAR); PHORBOL ESTER (PMA); PROTEIN KINASE C; RECEPTOR ACTIVATION;

CALCIUM COMPOUNDS; ENZYME ACTIVITY; ENZYME INHIBITION; ESTERS; PHOSPHORYLATION; PROTEINS;

ENZYME KINETICS;

CALCIUM PHOSPHATE; CALCIUM SENSING RECEPTOR; CALYCULIN A; PHOSPHATASE; PROTEIN KINASE C; 1 (3 METHOXYPHENYL) N (3 PHENYLPROPYL)ETHYLAMINE; ANILINE DERIVATIVE; CALCIUM; CARCINOGEN; ENZYME INHIBITOR; NPS R-467; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM SIGNALING; CELL STIMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME SUBSTRATE; EXTRACELLULAR CALCIUM; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; OSCILLATION; PARATHYROID CELL; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; STEREOCHEMISTRY; ANIMAL; CATTLE; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; MUTATION; PARATHYROID GLAND; PHOSPHORYLATION; PROTEIN PROCESSING;

BOVINAE;

ANILINE COMPOUNDS; ANIMALS; CALCIUM; CALCIUM SIGNALING; CARCINOGENS; CATTLE; CELL LINE; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; MUTATION; PARATHYROID GLANDS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, CALCIUM-SENSING; TETRADECANOYLPHORBOL ACETATE;

EID: 34447540344     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607469200     Document Type: Article

References (24)

1. Brown, E. M., Gamba, G., Riccardi, D., Lombardi, M., Butters, R., Kifor, O., Sun, A., Hediger, M. A., Lytton, J., and Hebert, S. C. (1993) Nature 366, 575-580
2. Brown, E. M., and MacLeod, R. J. (2001) Physiol. Rev. 81, 239-297
3. Membreno, L., Chen, T. H., Woodley, S., Gagucas, R., and Shoback, D. (1989) Endocrinology 124, 789-797
4. Racke, F. K., and Nemeth, E. F. (1993) J. Physiol. 468, 141-162
5. Racke, F. K., and Nemeth, E. F. (1993) J. Physiol. 468, 163-176
6. Garrett, J. E., Capuano, I. V., Hammerland, L. G., Hung, B. C., Brown, E. M., Hebert, S. C., Nemeth, E. F., and Fuller, F. (1995) J. Biol. Chem. 270, 12919-12925
7. Bai, M., Trivedi, S., Lane, C. R., Yang, Y., Quinn, S. J., and Brown, E. M. (1998) J. Biol. Chem. 273, 21267-21275
8. Jiang, Y. F., Zhang, Z., Kifor, O., Lane, C. R., Quinn, S. J., and Bai, M. (2002) J. Biol. Chem. 277, 50543-50549
9. Young, S. H., Wu, S. V., and Rozengurt, E. (2002) J. Biol. Chem. 277, 46871-46876
10. Ward, D. T., McLarnon, S. J., and Riccardi, D. (2002) J. Am. Soc. Nephrol. 13, 1481-1489
11. Davies, S. L., Gibbons, C. E., Vizard, T., and Ward, D. T. (2006) Am. J. Physiol. 290, C1543-C1551
12. Bai, M., Quinn, S., Trivedi, S., Kifor, O., Pearce, S. H., Pollak, M. R., Krapcho, K., Hebert, S. C., and Brown, E. M. (1996) J. Biol. Chem. 271, 19537-19545
13. Ward, D. T., Brown, E. M., and Harris, H. W. (1998) J. Biol. Chem. 273, 14476-14483
14. Bai, M., Trivedi, S., and Brown, E. M. (1998) J. Biol. Chem. 273, 23605-23610
15. Tanaka, M., Sagawa, S., Hoshi, J., Shimoma, F., Matsuda, I., Sakoda, K., Sasase, T., Shindo, M., and Inaba, T. (2004) Bioorg. Med. Chem. Lett. 14, 5171-5174
16. Nemeth, E. F., Delmar, E. G., Heaton, W. L., Miller, M. A., Lambert, L. D., Conklin, R. L., Gowen, M., Gleason, J. G., Bhatnagar, P. K., and Fox, J. (2001) J. Pharmacol. Exp. Ther. 299, 323-331
17. Dvorak, M. M., Siddiqua, A., Ward, D. T., Carter, D. H., Dallas, S. L., Nemeth, E. F., and Riccardi, D. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 5140-5145
18. Nishizuka, Y. (1986) Science 233, 305-312
19. Sakwe, A. M., Larsson, M., and Rask, L. (2004) Exp. Cell Res. 297, 560-573
20. Racke, F. K., and Nemeth, E. F. (1994) Am. J. Physiol. 267, E429-E438
21. Ishihara, H., Martin, B. L., Brautigan, D. L., Karaki, H., Ozaki, H., Kato, Y., Fusetani, N., Watabe, S., Hashimoto, K., Uemura, D., and Hartshorne, D. J. (1989) Biochem. Biophys. Res. Commun. 159, 871-877
22. Hosoya, N., Mitsui, M., Yazama, F., Ishihara, H., Ozaki, H., Karaki, H., Hartshorne, D. J., and Mohri, H. (1993) J. Cell Sci. 105, 883-890
23. Chartier, L., Rankin, L. L., Allen, R. E., Kato, Y., Fusetani, N., Karaki, H., Watabe, S., and Hartshorne, D. J. (1991) Cell Motil. Cytoskeleton. 18, 26-40
24. Li, Y. M., Mackintosh, C., and Casida, J. E. (1993) Biochem. Pharmacol. 46, 1435-1443