-
1
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen, C., Liu, Y., Liu, R., Ikenoue, T., Guan, K. L. and Zheng, P. (2008). TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 205, 2397-2408.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Zheng, P.6
-
2
-
-
0142136097
-
Dpp signaling silences bam transcription directly to establish asymmetric divisions of germline stem cells
-
Chen, D. and McKearin, D. (2003a). Dpp signaling silences bam transcription directly to establish asymmetric divisions of germline stem cells. Curr. Biol. 13, 1786-1791.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1786-1791
-
-
Chen, D.1
McKearin, D.2
-
3
-
-
0037352272
-
A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell
-
Chen, D. and McKearin, D. (2003b). A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell. Development 130, 1159-1170.
-
(2003)
Development
, vol.130
, pp. 1159-1170
-
-
Chen, D.1
McKearin, D.2
-
4
-
-
12544252115
-
Gene circuitry controlling a stem cell niche
-
Chen, D. and McKearin, D. (2005). Gene circuitry controlling a stem cell niche. Curr. Biol. 15, 179-184.
-
(2005)
Curr. Biol.
, vol.15
, pp. 179-184
-
-
Chen, D.1
McKearin, D.2
-
5
-
-
0031885720
-
Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells
-
Forbes, A. and Lehmann, R. (1998). Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells. Development 125, 679-690.
-
(1998)
Development
, vol.125
, pp. 679-690
-
-
Forbes, A.1
Lehmann, R.2
-
6
-
-
0034982971
-
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
-
Gao, X. and Pan, D. (2001). TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth. Genes Dev. 15, 1383-1392.
-
(2001)
Genes Dev.
, vol.15
, pp. 1383-1392
-
-
Gao, X.1
Pan, D.2
-
7
-
-
2642520551
-
Repression of primordial germ cell differentiation parallels germ line stem cell maintenance
-
Gilboa, L. and Lehmann, R. (2004). Repression of primordial germ cell differentiation parallels germ line stem cell maintenance. Curr. Biol. 14, 981-986.
-
(2004)
Curr. Biol.
, vol.14
, pp. 981-986
-
-
Gilboa, L.1
Lehmann, R.2
-
8
-
-
20544458318
-
Stem cell division is regulated by the microRNA pathway
-
Hatfield, S. D., Shcherbata, H. R., Fischer, K. A., Nakahara, K., Carthew, R. W. and Ruohola-Baker, H. (2005). Stem cell division is regulated by the microRNA pathway. Nature 435, 974-978.
-
(2005)
Nature
, vol.435
, pp. 974-978
-
-
Hatfield, S.D.1
Shcherbata, H.R.2
Fischer, K.A.3
Nakahara, K.4
Carthew, R.W.5
Ruohola-Baker, H.6
-
9
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
Inoki, K., Corradetti, M. N. and Guan, K. L. (2005). Dysregulation of the TSC-mTOR pathway in human disease. Nat. Genet. 37, 19-24.
-
(2005)
Nat. Genet.
, vol.37
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.L.3
-
10
-
-
0033582748
-
Gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle
-
Ito, N. and Rubin, G. M. (1999). gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle. Cell 96, 529-539.
-
(1999)
Cell
, vol.96
, pp. 529-539
-
-
Ito, N.1
Rubin, G.M.2
-
11
-
-
33947106486
-
Dcr-1 maintains Drosophila ovarian stem cells
-
Jin, Z. and Xie, T. (2007). Dcr-1 maintains Drosophila ovarian stem cells. Curr. Biol. 17, 539-544.
-
(2007)
Curr. Biol.
, vol.17
, pp. 539-544
-
-
Jin, Z.1
Xie, T.2
-
12
-
-
37549000504
-
Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary
-
Jin, Z., Kirilly, D., Weng, C., Kawase, E., Song, X., Smith, S., Schwartz, J. and Xie, T. (2008). Differentiation-defective stem cells outcompete normal stem cells for niche occupancy in the Drosophila ovary. Cell Stem Cell 2, 39-49.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 39-49
-
-
Jin, Z.1
Kirilly, D.2
Weng, C.3
Kawase, E.4
Song, X.5
Smith, S.6
Schwartz, J.7
Xie, T.8
-
13
-
-
77951202525
-
Direct inhibition of Pumilo activity by Bam and Bgcn in Drosophila germ line stem cell differentiation
-
Kim, J. Y., Lee, Y. C. and Kim, C. (2009). Direct inhibition of Pumilo activity by Bam and Bgcn in Drosophila germ line stem cell differentiation. J. Biol. Chem. 285, 4741-4746.
-
(2009)
J. Biol. Chem.
, vol.285
, pp. 4741-4746
-
-
Kim, J.Y.1
Lee, Y.C.2
Kim, C.3
-
14
-
-
33846226547
-
The Drosophila ovary: An active stem cell community
-
Kirilly, D. and Xie, T. (2007). The Drosophila ovary: an active stem cell community. Cell Res. 17, 15-25.
-
(2007)
Cell Res.
, vol.17
, pp. 15-25
-
-
Kirilly, D.1
Xie, T.2
-
15
-
-
27744588780
-
Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways
-
Kwiatkowski, D. J. and Manning, B. D. (2005). Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways. Hum. Mol. Genet. 14, R251-R258.
-
(2005)
Hum. Mol. Genet.
, vol.14
-
-
Kwiatkowski, D.J.1
Manning, B.D.2
-
16
-
-
0028329909
-
The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity
-
Lantz, V., Chang, J. S., Horabin, J. I., Bopp, D. and Schedl, P. (1994). The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity. Genes Dev. 8, 598-613.
-
(1994)
Genes Dev.
, vol.8
, pp. 598-613
-
-
Lantz, V.1
Chang, J.S.2
Horabin, J.I.3
Bopp, D.4
Schedl, P.5
-
17
-
-
28444486367
-
Stem cell niche: Structure and function
-
Li, L. and Xie, T. (2005). Stem cell niche: structure and function. Annu. Rev. Cell Dev. Biol. 21, 605-631.
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 605-631
-
-
Li, L.1
Xie, T.2
-
18
-
-
67249147425
-
Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance
-
Li, Y., Minor, N. T., Park, J. K., McKearin, D. M. and Maines, J. Z. (2009). Bam and Bgcn antagonize Nanos-dependent germ-line stem cell maintenance. Proc. Natl. Acad. Sci. USA 106, 9304-9309.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9304-9309
-
-
Li, Y.1
Minor, N.T.2
Park, J.K.3
McKearin, D.M.4
Maines, J.Z.5
-
19
-
-
0028214601
-
The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation
-
Lin, H., Yue, L. and Spradling, A. C. (1994). The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development 120, 947-956.
-
(1994)
Development
, vol.120
, pp. 947-956
-
-
Lin, H.1
Yue, L.2
Spradling, A.C.3
-
20
-
-
0029116370
-
A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells
-
McKearin, D. and Ohlstein, B. (1995). A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells. Development 121, 2937-2947.
-
(1995)
Development
, vol.121
, pp. 2937-2947
-
-
McKearin, D.1
Ohlstein, B.2
-
21
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
Montagne, J., Stewart, M. J., Stocker, H., Hafen, E., Kozma, S. C. and Thomas, G. (1999). Drosophila S6 kinase: a regulator of cell size. Science 285, 2126-2129.
-
(1999)
Science
, vol.285
, pp. 2126-2129
-
-
Montagne, J.1
Stewart, M.J.2
Stocker, H.3
Hafen, E.4
Kozma, S.C.5
Thomas, G.6
-
22
-
-
39149144034
-
Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life
-
Morrison, S. J. and Spradling, A. C. (2008). Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell 132, 598-611.
-
(2008)
Cell
, vol.132
, pp. 598-611
-
-
Morrison, S.J.1
Spradling, A.C.2
-
23
-
-
46749129531
-
Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage
-
Neumuller, R. A., Betschinger, J., Fischer, A., Bushati, N., Poernbacher, I., Mechtler, K., Cohen, S. M. and Knoblich, J. A. (2008). Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature 454, 241-245.
-
(2008)
Nature
, vol.454
, pp. 241-245
-
-
Neumuller, R.A.1
Betschinger, J.2
Fischer, A.3
Bushati, N.4
Poernbacher, I.5
Mechtler, K.6
Cohen, S.M.7
Knoblich, J.A.8
-
24
-
-
0030776177
-
Ectopic expression of the Drosophila Bam protein eliminates oogenic germline stem cells
-
Ohlstein, B. and McKearin, D. (1997). Ectopic expression of the Drosophila Bam protein eliminates oogenic germline stem cells. Development 124, 3651-3662.
-
(1997)
Development
, vol.124
, pp. 3651-3662
-
-
Ohlstein, B.1
McKearin, D.2
-
25
-
-
0033880901
-
Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila
-
Page, S. L., McKim, K. S., Deneen, B., Van Hook, T. L. and Hawley, R. S. (2000). Genetic studies of mei-P26 reveal a link between the processes that control germ cell proliferation in both sexes and those that control meiotic exchange in Drosophila. Genetics 155, 1757-1772.
-
(2000)
Genetics
, vol.155
, pp. 1757-1772
-
-
Page, S.L.1
McKim, K.S.2
Deneen, B.3
Van Hook, T.L.4
Hawley, R.S.5
-
26
-
-
33947107476
-
The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells
-
Park, J. K., Liu, X., Strauss, T. J., McKearin, D. M. and Liu, Q. (2007). The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells. Curr. Biol. 17, 533-538.
-
(2007)
Curr. Biol.
, vol.17
, pp. 533-538
-
-
Park, J.K.1
Liu, X.2
Strauss, T.J.3
McKearin, D.M.4
Liu, Q.5
-
27
-
-
0035805162
-
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
-
Potter, C. J., Huang, H. and Xu, T. (2001). Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell 105, 357-368.
-
(2001)
Cell
, vol.105
, pp. 357-368
-
-
Potter, C.J.1
Huang, H.2
Xu, T.3
-
28
-
-
0028244539
-
Morphogenesis of Drosophila ovarian ring canals
-
Robinson, D. N., Cant, K. and Cooley, L. (1994). Morphogenesis of Drosophila ovarian ring canals. Development 120, 2015-2025.
-
(1994)
Development
, vol.120
, pp. 2015-2025
-
-
Robinson, D.N.1
Cant, K.2
Cooley, L.3
-
29
-
-
0037069338
-
DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary
-
Song, X. and Xie, T. (2002). DE-cadherin-mediated cell adhesion is essential for maintaining somatic stem cells in the Drosophila ovary. Proc. Natl. Acad. Sci. USA 99, 14813-14818.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14813-14818
-
-
Song, X.1
Xie, T.2
-
30
-
-
0037036134
-
Germline stem cells anchored by adherens junctions in the Drosophila ovary niches
-
Song, X., Zhu, C. H., Doan, C. and Xie, T. (2002). Germline stem cells anchored by adherens junctions in the Drosophila ovary niches. Science 296, 1855-1857.
-
(2002)
Science
, vol.296
, pp. 1855-1857
-
-
Song, X.1
Zhu, C.H.2
Doan, C.3
Xie, T.4
-
31
-
-
1842559510
-
Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary
-
Song, X., Wong, M. D., Kawase, E., Xi, R., Ding, B. C., McCarthy, J. J. and Xie, T. (2004). Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary. Development 131, 1353-1364.
-
(2004)
Development
, vol.131
, pp. 1353-1364
-
-
Song, X.1
Wong, M.D.2
Kawase, E.3
Xi, R.4
Ding, B.C.5
McCarthy, J.J.6
Xie, T.7
-
32
-
-
12544258206
-
Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell selfrenewal and differentiation
-
Szakmary, A., Cox, D. N., Wang, Z. and Lin, H. (2005). Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell selfrenewal and differentiation. Curr. Biol. 15, 171-178.
-
(2005)
Curr. Biol.
, vol.15
, pp. 171-178
-
-
Szakmary, A.1
Cox, D.N.2
Wang, Z.3
Lin, H.4
-
33
-
-
0035805180
-
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
-
Tapon, N., Ito, N., Dickson, B. J., Treisman, J. E. and Hariharan, I. K. (2001). The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105, 345-355.
-
(2001)
Cell
, vol.105
, pp. 345-355
-
-
Tapon, N.1
Ito, N.2
Dickson, B.J.3
Treisman, J.E.4
Hariharan, I.K.5
-
34
-
-
1642387326
-
Nanos maintains germline stem cell self-renewal by preventing differentiation
-
Wang, Z. and Lin, H. (2004). Nanos maintains germline stem cell self-renewal by preventing differentiation. Science 303, 2016-2019.
-
(2004)
Science
, vol.303
, pp. 2016-2019
-
-
Wang, Z.1
Lin, H.2
-
35
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger, S., Loewith, R. and Hall, M. N. (2006). TOR signaling in growth and metabolism. Cell 124, 471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
36
-
-
31144450299
-
Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway
-
Xi, R., Doan, C., Liu, D. and Xie, T. (2005). Pelota controls self-renewal of germline stem cells by repressing a Bam-independent differentiation pathway. Development 132, 5365-5374.
-
(2005)
Development
, vol.132
, pp. 5365-5374
-
-
Xi, R.1
Doan, C.2
Liu, D.3
Xie, T.4
-
37
-
-
0032563165
-
Decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary
-
Xie, T. and Spradling, A. C. (1998). decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell 94, 251-260.
-
(1998)
Cell
, vol.94
, pp. 251-260
-
-
Xie, T.1
Spradling, A.C.2
-
38
-
-
0034644602
-
A niche maintaining germ line stem cells in the Drosophila ovary
-
Xie, T. and Spradling, A. C. (2000). A niche maintaining germ line stem cells in the Drosophila ovary. Science 290, 328-330.
-
(2000)
Science
, vol.290
, pp. 328-330
-
-
Xie, T.1
Spradling, A.C.2
-
39
-
-
0027267041
-
Analysis of genetic mosaics in developing and adult Drosophila tissues
-
Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
-
(1993)
Development
, vol.117
, pp. 1223-1237
-
-
Xu, T.1
Rubin, G.M.2
-
40
-
-
38349006273
-
Argonaute 1 regulates the fate of germline stem cells in Drosophila
-
Yang, L., Chen, D., Duan, R., Xia, L., Wang, J., Qurashi, A. and Jin, P. (2007). Argonaute 1 regulates the fate of germline stem cells in Drosophila. Development 134, 4265-4272.
-
(2007)
Development
, vol.134
, pp. 4265-4272
-
-
Yang, L.1
Chen, D.2
Duan, R.3
Xia, L.4
Wang, J.5
Qurashi, A.6
Jin, P.7
-
41
-
-
0034312315
-
Regulation of cellular growth by the Drosophila target of rapamycin dTOR
-
Zhang, H., Stallock, J. P., Ng, J. C., Reinhard, C. and Neufeld, T. P. (2000). Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes Dev. 14, 2712-2724.
-
(2000)
Genes Dev.
, vol.14
, pp. 2712-2724
-
-
Zhang, H.1
Stallock, J.P.2
Ng, J.C.3
Reinhard, C.4
Neufeld, T.P.5
-
42
-
-
43449113881
-
Age-related changes of germline stem cell activity, niche signaling activity and egg production in Drosophila
-
Zhao, R., Xuan, Y., Li, X. and Xi, R. (2008). Age-related changes of germline stem cell activity, niche signaling activity and egg production in Drosophila. Aging Cell 7, 344-354.
-
(2008)
Aging Cell
, vol.7
, pp. 344-354
-
-
Zhao, R.1
Xuan, Y.2
Li, X.3
Xi, R.4
|