Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene

Genesis

Volumn 32, Issue 2, 2002, Pages 148-149

  Lesche, Ralf ^a,d   Groszer, Matthias ^a   Gao, Jing ^a   Wang, Ying ^a   Messing, Albee ^b   Sun, Hong ^c   Liu, Xin ^a   Wu, Hong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d EPIGENOMICS AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GANCICLOVIR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ARTICLE; CANCER SUSCEPTIBILITY; CHIMERA; CHROMOSOME 19; DELETION MUTANT; GENE INACTIVATION; GENE SEQUENCE; GENOTYPE; GERM LINE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; GENE SILENCING; GENES, TUMOR SUPPRESSOR; INTEGRASES; MICE; MICE, TRANSGENIC; PHOSPHORIC MONOESTER HYDROLASES; PTEN PHOSPHOHYDROLASE; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR PROTEINS; VIRAL PROTEINS;

MURINAE;

EID: 0036195102     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10036     Document Type: Article

References (7)

1. New insight into tumor suppression: PTEN suppress tumor formation by restraining the phosphoiniside 3-kinase/AKT pathway
2. Pten, a unique tumor suppressor gene
3. Pten is essential for embryonic development and tumour suppression
4. Genetics of cowden syndrome: Through the looking glass of oncology
5. Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
6. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
7. hGFAP-Cre transgenic mice for manipulation of glial and neuronal function in vivo