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Volumn 68, Issue 22, 2011, Pages 3675-3685

The potter's wheel: The host's role in sculpting its microbiota

Author keywords

Antimicrobial peptide; Bacteria; Defensin; Dysbiosis; Homeostasis; Immunoglobulin a; Intestine; Microbial colonization; Microflora; Mucosa; Mucus

Indexed keywords

ALPHA DEFENSIN; BETA DEFENSIN; CASPASE RECRUITMENT DOMAIN PROTEIN 4; DEFENSIN; FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 2; GLYCAN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; MATRILYSIN; MYELOID DIFFERENTIATION FACTOR 88; OLIGOSACCHARIDE; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

EID: 82155195889     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0830-3     Document Type: Review
Times cited : (103)

References (85)
  • 1
    • 33745594044 scopus 로고    scopus 로고
    • The gut flora as a forgotten organ
    • DOI 10.1038/sj.embor.7400731, PII 7400731
    • O'Hara AM, Shanahan F (2006) The gut flora as a forgotten organ. EMBO Rep 7(7):688-693. PMCID:16819463 (Pubitemid 43986264)
    • (2006) EMBO Reports , vol.7 , Issue.7 , pp. 688-693
    • O'Hara, A.M.1    Shanahan, F.2
  • 2
    • 77954859068 scopus 로고    scopus 로고
    • Why bacteria matter in animal development and evolution
    • Fraune S, Bosch TC (2010) Why bacteria matter in animal development and evolution. Bioessays 32(7):571-580
    • (2010) Bioessays , vol.32 , Issue.7 , pp. 571-580
    • Fraune, S.1    Bosch, T.C.2
  • 4
    • 77954607064 scopus 로고    scopus 로고
    • A pathobiont of the microbiota balances host colonization and intestinal inflammation
    • Chow J, Mazmanian SK (2010) A pathobiont of the microbiota balances host colonization and intestinal inflammation. Cell Host Microbe 7(4):265-276
    • (2010) Cell Host Microbe , vol.7 , Issue.4 , pp. 265-276
    • Chow, J.1    Mazmanian, S.K.2
  • 5
    • 0017341656 scopus 로고
    • Microbial ecology of the gastrointestinal tract
    • Savage DC (1977) Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 31:107-133
    • (1977) Annu Rev Microbiol , vol.31 , pp. 107-133
    • Savage, D.C.1
  • 7
    • 79955025122 scopus 로고    scopus 로고
    • Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice
    • PMCID:3076821
    • Goodman AL, Kallstrom G, Faith JJ, Reyes A, Moore A, Dantas G et al (2011) Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice. Proc Natl Acad Sci USA 108(15):6252-6257. PMCID:3076821
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.15 , pp. 6252-6257
    • Goodman, A.L.1    Kallstrom, G.2    Faith, J.J.3    Reyes, A.4    Moore, A.5    Dantas, G.6
  • 8
    • 79952763661 scopus 로고    scopus 로고
    • Succession of microbial consortia in the developing infant gut microbiome
    • PMCID:3063592
    • Koenig JE, Spor A, Scalfone N, Fricker AD, Stombaugh J, Knight R et al (2011) Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci USA 108(Suppl 1):4578-4585. PMCID:3063592
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.1 SUPPL. , pp. 4578-4585
    • Koenig, J.E.1    Spor, A.2    Scalfone, N.3    Fricker, A.D.4    Stombaugh, J.5    Knight, R.6
  • 10
    • 56849106496 scopus 로고    scopus 로고
    • The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rrna sequencing
    • PMCID:17943117
    • Dethlefsen L, Huse S, Sogin ML, Relman DA (2008) The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rrna sequencing. PLoS Biology 6(11):e280. PMCID:17943117
    • (2008) PLoS Biology , vol.6 , Issue.11
    • Dethlefsen, L.1    Huse, S.2    Sogin, M.L.3    Relman, D.A.4
  • 13
    • 72949091232 scopus 로고    scopus 로고
    • Bacterial community variation in human body habitats across space and time
    • Costello EK, Lauber CL, Hamady M, Fierer N, Gordon JI, Knight R (2009) Bacterial community variation in human body habitats across space and time. Science 326(5960):1694-1697
    • (2009) Science , vol.326 , Issue.5960 , pp. 1694-1697
    • Costello, E.K.1    Lauber, C.L.2    Hamady, M.3    Fierer, N.4    Gordon, J.I.5    Knight, R.6
  • 14
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C et al (2010) A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464(7285):59-65
    • (2010) Nature , vol.464 , Issue.7285 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 17
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • DOI 10.1126/science.1104816
    • Backhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI (2005) Host-bacterial mutualism in the human intestine. Science 307(5717):1915-1920. PMCID:15790844 (Pubitemid 40404694)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1915-1920
    • Backhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3    Peterson, D.A.4    Gordon, J.I.5
  • 18
    • 77956417881 scopus 로고    scopus 로고
    • Mucosal control of the intestinal microbial community
    • Brugman S, Nieuwenhuis EE (2010) Mucosal control of the intestinal microbial community. J Mol Med 88(9):881-888
    • (2010) J Mol Med , vol.88 , Issue.9 , pp. 881-888
    • Brugman, S.1    Nieuwenhuis, E.E.2
  • 19
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper LV, Macpherson AJ (2010) Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 10(3):159-169
    • (2010) Nat Rev Immunol , vol.10 , Issue.3 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 20
    • 77955655862 scopus 로고    scopus 로고
    • Microbiota-stimulated immune mechanisms to maintain gut homeostasis
    • Chung H, Kasper DL (2010) Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Curr Opin Immunol 22:455-460
    • (2010) Curr Opin Immunol , vol.22 , pp. 455-460
    • Chung, H.1    Kasper, D.L.2
  • 22
    • 33749997498 scopus 로고    scopus 로고
    • Reciprocal Gut Microbiota Transplants from Zebrafish and Mice to Germ-free Recipients Reveal Host Habitat Selection
    • DOI 10.1016/j.cell.2006.08.043, PII S0092867406012268
    • Rawls JF, Mahowald MA, Ley RE, Gordon JI (2006) Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell 127:423-433 (Pubitemid 44572375)
    • (2006) Cell , vol.127 , Issue.2 , pp. 423-433
    • Rawls, J.F.1    Mahowald, M.A.2    Ley, R.E.3    Gordon, J.I.4
  • 23
    • 78649978358 scopus 로고    scopus 로고
    • Evolutionary relationships of wild hominids recapitulated by gut microbial communities
    • PMCID:2982803
    • Ochman H, Worobey M, Kuo CH, Ndjango JB, Peeters M, Hahn BH et al (2010) Evolutionary relationships of wild hominids recapitulated by gut microbial communities. PLoS Biology 8(11):e1000546. PMCID:2982803
    • (2010) PLoS Biology , vol.8 , Issue.11
    • Ochman, H.1    Worobey, M.2    Kuo, C.H.3    Ndjango, J.B.4    Peeters, M.5    Hahn, B.H.6
  • 24
    • 70350125099 scopus 로고    scopus 로고
    • Human gut microbiome adopts an alternative state following small bowel transplantation
    • PMCID:2746123
    • Hartman AL, Lough DM, Barupal DK, Fiehn O, Fishbein T, Zasloff M et al (2009) Human gut microbiome adopts an alternative state following small bowel transplantation. Proc Natl Acad Sci USA 106(40):17187-17192. PMCID:2746123
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.40 , pp. 17187-17192
    • Hartman, A.L.1    Lough, D.M.2    Barupal, D.K.3    Fiehn, O.4    Fishbein, T.5    Zasloff, M.6
  • 25
    • 0029845965 scopus 로고    scopus 로고
    • A model of host-microbial interactions in an open mammalian ecosystem
    • Bry L, Falk PG, Midtvedt T, Gordon JI (1996) A model of hostmicrobial interactions in an open mammalian ecosystem. Science 273(5280):1380-1383 (Pubitemid 26296524)
    • (1996) Science , vol.273 , Issue.5280 , pp. 1380-1383
    • Bry, L.1    Falk, P.G.2    Midtvedt, T.3    Gordon, J.I.4
  • 27
    • 79956257405 scopus 로고    scopus 로고
    • Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine
    • PMCID: 3098274
    • Wacklin P, Makivuokko H, Alakulppi N, Nikkila J, Tenkanen H, Rabina J, et al (2011) Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine. PLoS One 6(5):e20113. PMCID: 3098274
    • (2011) PLoS One , vol.6 , Issue.5
    • Wacklin, P.1    Makivuokko, H.2    Alakulppi, N.3    Nikkila, J.4    Tenkanen, H.5    Rabina, J.6
  • 28
    • 77954142215 scopus 로고    scopus 로고
    • Nursing our microbiota: Molecular linkages between bifidobacteria and milk oligosaccharides
    • PMCID:2902656
    • Sela DA, Mills DA (2010) Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosaccharides. Trends Microbiol 18(7):298-307. PMCID:2902656
    • (2010) Trends Microbiol , vol.18 , Issue.7 , pp. 298-307
    • Sela, D.A.1    Mills, D.A.2
  • 29
    • 79952742717 scopus 로고    scopus 로고
    • Human milk glycobiome and its impact on the infant gastrointestinal microbiota
    • PMCID:3063602
    • Zivkovic AM, German JB, Lebrilla CB, Mills DA (2011) Human milk glycobiome and its impact on the infant gastrointestinal microbiota. Proc Natl Acad Sci USA 108 [Suppl 1]: 4653-4658. PMCID:3063602
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.1 SUPPL. , pp. 4653-4658
    • Zivkovic, A.M.1    German, J.B.2    Lebrilla, C.B.3    Mills, D.A.4
  • 30
    • 36148991870 scopus 로고    scopus 로고
    • Glycoprofiling of bifidobacterial consumption of human milk oligosaccharides demonstrates strain specific, preferential consumption of small chain glycans secreted in early human lactation
    • DOI 10.1021/jf0710480
    • locascio RG, Ninonuevo MR, Freeman SL, Sela DA, Grimm R, Lebrilla CB et al (2007) Glycoprofiling of bifidobacterial consumption of human milk oligosaccharides demonstrates strain specific, preferential consumption of small chain glycans secreted in early human lactation. J Agric Food Chem 55(22):8914-8919 (Pubitemid 350105536)
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.22 , pp. 8914-8919
    • LoCascio, R.G.1    Ninonuevo, M.R.2    Freeman, S.L.3    Sela, D.A.4    Grimm, R.5    Lebrilla, C.B.6    Mills, D.A.7    German, J.B.8
  • 31
    • 57749113201 scopus 로고    scopus 로고
    • The genome sequence of Bifidobacterium longum subsp. Infantis reveals adaptations for milk utilization within the infant microbiome
    • PMCID:2596198
    • Sela DA, Chapman J, Adeuya A, Kim JH, Chen F, Whitehead TR et al (2008) The genome sequence of Bifidobacterium longum subsp. Infantis reveals adaptations for milk utilization within the infant microbiome. Proc Natl Acad Sci USA 105(48):18964-18969. PMCID:2596198
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.48 , pp. 18964-18969
    • Sela, D.A.1    Chapman, J.2    Adeuya, A.3    Kim, J.H.4    Chen, F.5    Whitehead, T.R.6
  • 32
    • 77958509786 scopus 로고    scopus 로고
    • The role of mucosal immunity and host genetics in defining intestinal commensal bacteria
    • Hansen J, Gulati A, Sartor RB (2010) The role of mucosal immunity and host genetics in defining intestinal commensal bacteria. Curr Opin Gastroenterol 26(6):564-571
    • (2010) Curr Opin Gastroenterol , vol.26 , Issue.6 , pp. 564-571
    • Hansen, J.1    Gulati, A.2    Sartor, R.B.3
  • 33
    • 0031768678 scopus 로고    scopus 로고
    • Creating and maintaining the gastrointestinal ecosystem: What we know and need to know from gnotobiology
    • Falk PG, Hooper LV, Midtvedt T, Gordon JI (1998) Creating and maintaining the gastrointestinal ecosystem: what we know and need to know from gnotobiology. Microbiol Mol Biol Rev 62(4):1157-1170 (Pubitemid 28558295)
    • (1998) Microbiology and Molecular Biology Reviews , vol.62 , Issue.4 , pp. 1157-1170
    • Falk, P.G.1    Hooper, L.V.2    Midtvedt, T.3    Gordon, J.I.4
  • 34
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round JL, Mazmanian SK (2009) The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9:313-323
    • (2009) Nat Rev Immunol , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 35
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • DOI 10.1038/nature07450, PII NATURE07450
    • Bouskra D, Brezillon C, Berard M, Werts C, Varona R, Boneca IG et al (2008) Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 456(7221):507-510 (Pubitemid 352759006)
    • (2008) Nature , vol.456 , Issue.7221 , pp. 507-510
    • Bouskra, D.1    Brezillon, C.2    Berard, M.3    Werts, C.4    Varona, R.5    Boneca, I.G.6    Eberl, G.7
  • 36
    • 0037340434 scopus 로고    scopus 로고
    • Angiogenins: A new class of microbicidal proteins involved in innate immunity
    • DOI 10.1038/ni888
    • Hooper LV, Stappenbeck TS, Hong CV, Gordon JI (2003) Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol 4:269-273 (Pubitemid 36322137)
    • (2003) Nature Immunology , vol.4 , Issue.3 , pp. 269-273
    • Hooper, L.V.1    Stappenbeck, T.S.2    Hong, C.V.3    Gordon, J.I.4
  • 37
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • DOI 10.1126/science.1127119
    • Cash HL, Whitham CV, Behrendt CL, Hooper LV (2006) Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313(5790):1126-1130 (Pubitemid 44300239)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 38
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • DOI 10.1016/j.cell.2005.05.007, PII S0092867405004514
    • Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL (2005) An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 122(1):107-118 (Pubitemid 40977944)
    • (2005) Cell , vol.122 , Issue.1 , pp. 107-118
    • Mazmanian, S.K.1    Cui, H.L.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 41
    • 79952748335 scopus 로고    scopus 로고
    • The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions
    • Johansson ME, Larsson JM, Hansson GC (2011) The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci USA 108 [Suppl 1]: 4659-4665
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.1 SUPPL. , pp. 4659-4665
    • Johansson, M.E.1    Larsson, J.M.2    Hansson, G.C.3
  • 42
    • 77954858707 scopus 로고    scopus 로고
    • The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
    • PMCID: 3035142
    • Hansson GC, Johansson ME (2010) The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Gut Microbes 1(1):51-54. PMCID: 3035142.
    • (2010) Gut Microbes , vol.1 , Issue.1 , pp. 51-54
    • Hansson, G.C.1    Johansson, M.E.2
  • 43
    • 78650840359 scopus 로고    scopus 로고
    • Adaptive immunity in the host-microbiota dialog
    • Feng T, Elson CO (2011) Adaptive immunity in the host-microbiota dialog. Mucosal Immunol 4(1):15-21
    • (2011) Mucosal Immunol , vol.4 , Issue.1 , pp. 15-21
    • Feng, T.1    Elson, C.O.2
  • 44
    • 73349099737 scopus 로고    scopus 로고
    • A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota
    • Cong Y, Feng T, Fujihashi K, Schoeb TR, Elson CO (2009) A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota. Proc Natl Acad Sci USA 106(46):19256-19261
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.46 , pp. 19256-19261
    • Cong, Y.1    Feng, T.2    Fujihashi, K.3    Schoeb, T.R.4    Elson, C.O.5
  • 45
    • 77953610970 scopus 로고    scopus 로고
    • Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa
    • Bergstrom KS, Kissoon-Singh V, Gibson DL, Ma C, Montero M, Sham HP et al (2010) Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathogens 6(5):e1000902
    • (2010) PLoS Pathogens , vol.6 , Issue.5
    • Bergstrom, K.S.1    Kissoon-Singh, V.2    Gibson, D.L.3    Ma, C.4    Montero, M.5    Sham, H.P.6
  • 46
    • 79953307656 scopus 로고    scopus 로고
    • Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice
    • Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E et al (2011) Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J Clin Invest 121(4):1657-1666
    • (2011) J Clin Invest , vol.121 , Issue.4 , pp. 1657-1666
    • Fu, J.1    Wei, B.2    Wen, T.3    Johansson, M.E.4    Liu, X.5    Bradford, E.6
  • 47
    • 77954051526 scopus 로고    scopus 로고
    • Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses
    • Hapfelmeier S, Lawson MA, Slack E, Kirundi JK, Stoel M, Heikenwalder M et al (2010) Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses. Science 328(5986):1705-1709
    • (2010) Science , vol.328 , Issue.5986 , pp. 1705-1709
    • Hapfelmeier, S.1    Lawson, M.A.2    Slack, E.3    Kirundi, J.K.4    Stoel, M.5    Heikenwalder, M.6
  • 48
    • 0037112050 scopus 로고    scopus 로고
    • Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora
    • DOI 10.1126/science.1077336
    • Fagarasan S, Muramatsu M, Suzuki K, Nagaoka H, Hiai H, Honjo T (2002) Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science 298(5597):1424-1427 (Pubitemid 35346143)
    • (2002) Science , vol.298 , Issue.5597 , pp. 1424-1427
    • Fagarasan, S.1    Muramatsu, M.2    Suzuki, K.3    Nagaoka, H.4    Hiai, H.5    Honjo, T.6
  • 50
    • 0028933794 scopus 로고
    • Peptide antibiotics and their role in innate immunity
    • Boman HG (1995) Peptide antibiotics and their role in innate immunity. Annu Rev Immunol 13:61-92
    • (1995) Annu Rev Immunol , vol.13 , pp. 61-92
    • Boman, H.G.1
  • 51
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • DOI 10.1038/415389a
    • Zasloff M (2002) Antimicrobial peptides of multicellular organisms. Nature 415(6870):389-395 (Pubitemid 34100944)
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1
  • 52
    • 78149248987 scopus 로고    scopus 로고
    • In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides
    • PMCID:2964230
    • Fraune S, Augustin R, Anton-Erxleben F, Wittlieb J, Gelhaus C, Klimovich VB et al (2010) In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides. Proc Natl Acad Sci USA 107(42):18067-18072. PMCID:2964230
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.42 , pp. 18067-18072
    • Fraune, S.1    Augustin, R.2    Anton-Erxleben, F.3    Wittlieb, J.4    Gelhaus, C.5    Klimovich, V.B.6
  • 53
    • 38949153861 scopus 로고    scopus 로고
    • Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila
    • Ryu JH, Kim SH, Lee HY, Bai JY, Nam YD, Bae JW et al (2008) Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila. Science 319(5864):777-782
    • (2008) Science , vol.319 , Issue.5864 , pp. 777-782
    • Ryu, J.H.1    Kim, S.H.2    Lee, H.Y.3    Bai, J.Y.4    Nam, Y.D.5    Bae, J.W.6
  • 55
    • 58549111588 scopus 로고    scopus 로고
    • Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface
    • PMCID:19075245
    • Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV (2008) Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci USA 105(52):20858-20863. PMCID:19075245
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.52 , pp. 20858-20863
    • Vaishnava, S.1    Behrendt, C.L.2    Ismail, A.S.3    Eckmann, L.4    Hooper, L.V.5
  • 57
    • 77958460117 scopus 로고    scopus 로고
    • Paneth cells and innate mucosal immunity
    • Ouellette AJ (2010) Paneth cells and innate mucosal immunity. Curr Opin Gastroenterol 26(6):547-553
    • (2010) Curr Opin Gastroenterol , vol.26 , Issue.6 , pp. 547-553
    • Ouellette, A.J.1
  • 58
    • 79954915318 scopus 로고    scopus 로고
    • Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
    • Bevins CL, Salzman NH (2011) Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. Nat Rev Microbiol 9(5):356-368
    • (2011) Nat Rev Microbiol , vol.9 , Issue.5 , pp. 356-368
    • Bevins, C.L.1    Salzman, N.H.2
  • 61
    • 13244292161 scopus 로고    scopus 로고
    • Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
    • DOI 10.1126/science.1104911
    • Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G et al (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307(5710):731-734 (Pubitemid 40194644)
    • (2005) Science , vol.307 , Issue.5710 , pp. 731-734
    • Kobayashi, K.S.1    Chamaillard, M.2    Ogura, Y.3    Henegariu, O.4    Inohara, N.5    Nunez, G.6    Flavell, R.A.7
  • 62
    • 77957047689 scopus 로고    scopus 로고
    • Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
    • PMCID:2930434
    • Biswas A, Liu YJ, Hao L, Mizoguchi A, Salzman NH, Bevins CL et al (2010) Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum. Proc Natl Acad Sci USA 107(33):14739-14744. PMCID:2930434
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.33 , pp. 14739-14744
    • Biswas, A.1    Liu, Y.J.2    Hao, L.3    Mizoguchi, A.4    Salzman, N.H.5    Bevins, C.L.6
  • 63
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB et al (2008) Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 4(4):337-349
    • (2008) Cell Host Microbe , vol.4 , Issue.4 , pp. 337-349
    • Ivanov, I.I.1    Rde, L.F.2    Manel, N.3    Yoshinaga, K.4    Rifkin, D.B.5    Sartor, R.B.6
  • 64
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U et al (2009) Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 139(3):485-498
    • (2009) Cell , vol.139 , Issue.3 , pp. 485-498
    • Ivanov, I.I.1    Atarashi, K.2    Manel, N.3    Brodie, E.L.4    Shima, T.5    Karaoz, U.6
  • 65
    • 70349742524 scopus 로고    scopus 로고
    • The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
    • Gaboriau-Routhiau V, Rakotobe S, Lecuyer E, Mulder I, Lan A, Bridonneau C et al (2009) The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity 31(4):677-689
    • (2009) Immunity , vol.31 , Issue.4 , pp. 677-689
    • Gaboriau-Routhiau, V.1    Rakotobe, S.2    Lecuyer, E.3    Mulder, I.4    Lan, A.5    Bridonneau, C.6
  • 67
    • 78751653584 scopus 로고    scopus 로고
    • Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1
    • Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J et al (2011) Reduction of disulphide bonds unmasks potent antimicrobial activity of human beta-defensin 1. Nature 469(7330):419-423
    • (2011) Nature , vol.469 , Issue.7330 , pp. 419-423
    • Schroeder, B.O.1    Wu, Z.2    Nuding, S.3    Groscurth, S.4    Marcinowski, M.5    Beisner, J.6
  • 70
    • 76549112175 scopus 로고    scopus 로고
    • Crypt abscess-associated microbiota in inflammatory bowel disease and acute self-limited colitis
    • PMCID:2816270
    • Sokol H, Vasquez N, Hoyeau-Idrissi N, Seksik P, Beaugerie L, Lavergne-Slove A et al (2010) Crypt abscess-associated microbiota in inflammatory bowel disease and acute self-limited colitis. World J Gastroenterol 16(5):583-587. PMCID:2816270
    • (2010) World J Gastroenterol , vol.16 , Issue.5 , pp. 583-587
    • Sokol, H.1    Vasquez, N.2    Hoyeau-Idrissi, N.3    Seksik, P.4    Beaugerie, L.5    Lavergne-Slove, A.6
  • 71
    • 79952745080 scopus 로고    scopus 로고
    • Experimental inflammatory bowel disease: Insights into the host-microbiota dialog
    • Saleh M, Elson CO (2011) Experimental inflammatory bowel disease: insights into the host-microbiota dialog. Immunity 34(3):293-302
    • (2011) Immunity , vol.34 , Issue.3 , pp. 293-302
    • Saleh, M.1    Elson, C.O.2
  • 72
    • 34547684651 scopus 로고    scopus 로고
    • Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae
    • DOI 10.1016/j.chom.2007.06.010, PII S1931312807001576
    • Lupp C, Robertson ML, Wickham ME, Sekirov I, Champion OL, Gaynor EC et al (2007) Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe 2(2):119-129 (Pubitemid 47209521)
    • (2007) Cell Host and Microbe , vol.2 , Issue.2 , pp. 119-129
    • Lupp, C.1    Robertson, M.L.2    Wickham, M.E.3    Sekirov, I.4    Champion, O.L.5    Gaynor, E.C.6    Finlay, B.B.7
  • 73
    • 40749084834 scopus 로고    scopus 로고
    • Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract
    • DOI 10.1128/IAI.01432-07
    • Barman M, Unold D, Shifley K, Amir E, Hung K, Bos N et al (2008) Enteric Salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract. Infect Immun 76(3):907-915 (Pubitemid 351428049)
    • (2008) Infection and Immunity , vol.76 , Issue.3 , pp. 907-915
    • Barman, M.1    Unold, D.2    Shifley, K.3    Amir, E.4    Hung, K.5    Bos, N.6    Salzman, N.7
  • 74
    • 35649026345 scopus 로고    scopus 로고
    • Salmonella enteric serovar typhimurium exploits inflammation to compete with the intestinal microbiota
    • Stecher B, Robbiani R, Walker AW, Westendorf AM, Barthei M, Kremer M et al (2007) Salmonella enteric serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biology 5(10):e244
    • (2007) PLoS Biology , vol.5 , Issue.10
    • Stecher, B.1    Robbiani, R.2    Walker, A.W.3    Westendorf, A.M.4    Barthei, M.5    Kremer, M.6
  • 75
    • 67650076454 scopus 로고    scopus 로고
    • Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection
    • Croswell A, Amir E, Teggatz P, Barman M, Salzman NH (2009) Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection. Infect Immun 77(7):2741-2753
    • (2009) Infect Immun , vol.77 , Issue.7 , pp. 2741-2753
    • Croswell, A.1    Amir, E.2    Teggatz, P.3    Barman, M.4    Salzman, N.H.5
  • 76
    • 53649106826 scopus 로고    scopus 로고
    • Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection
    • Sekirov I, Tam NM, Jogova M, Robertson ML, Li Y, Lupp C et al (2008) Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun 76(10):4726-4736
    • (2008) Infect Immun , vol.76 , Issue.10 , pp. 4726-4736
    • Sekirov, I.1    Tam, N.M.2    Jogova, M.3    Robertson, M.L.4    Li, Y.5    Lupp, C.6
  • 77
    • 65549099573 scopus 로고    scopus 로고
    • Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine
    • PMCID:2768556
    • Raffatellu M, George MD, Akiyama Y, Hornsby MJ, Nuccio SP, Paixao TA et al (2009) Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe 5(5):476-486. PMCID:2768556
    • (2009) Cell Host Microbe , vol.5 , Issue.5 , pp. 476-486
    • Raffatellu, M.1    George, M.D.2    Akiyama, Y.3    Hornsby, M.J.4    Nuccio, S.P.5    Paixao, T.A.6
  • 78
    • 77957157893 scopus 로고    scopus 로고
    • Gut inflammation provides a respiratory electron acceptor for Salmonella
    • PMCID:2946174
    • Winter SE, Thiennimitr P, Winter MG, Butler BP, Huseby DL, Crawford RW et al (2010) Gut inflammation provides a respiratory electron acceptor for Salmonella. Nature 467(7314):426-429. PMCID:2946174
    • (2010) Nature , vol.467 , Issue.7314 , pp. 426-429
    • Winter, S.E.1    Thiennimitr, P.2    Winter, M.G.3    Butler, B.P.4    Huseby, D.L.5    Crawford, R.W.6
  • 79
    • 77950353786 scopus 로고    scopus 로고
    • Homeostasis and inflammation in the intestine
    • Garrett WS, Gordon JI, Glimcher LH (2010) Homeostasis and inflammation in the intestine. Cell 140(6):859-870
    • (2010) Cell , vol.140 , Issue.6 , pp. 859-870
    • Garrett, W.S.1    Gordon, J.I.2    Glimcher, L.H.3
  • 80
    • 44649118583 scopus 로고    scopus 로고
    • Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases
    • DOI 10.1016/j.chom.2008.05.001, PII S1931312808001492
    • Peterson DA, Frank DN, Pace NR, Gordon JI (2008) Metagenomic approaches for defining the pathogenesis of inflammatory bowel diseases. Cell Host Microbe 3(6):417-427 (Pubitemid 351773097)
    • (2008) Cell Host and Microbe , vol.3 , Issue.6 , pp. 417-427
    • Peterson, D.A.1    Frank, D.N.2    Pace, N.R.3    Gordon, J.I.4
  • 81
    • 79952748287 scopus 로고    scopus 로고
    • Unravelling the effects of the environment and host genotype on the gut microbiome
    • Spor A, Koren O, Ley R (2011) Unravelling the effects of the environment and host genotype on the gut microbiome. Nat Rev Microbiol 9(4):279-290
    • (2011) Nat Rev Microbiol , vol.9 , Issue.4 , pp. 279-290
    • Spor, A.1    Koren, O.2    Ley, R.3


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