Crypt abscess-associated microbiota in inflammatory bowel disease and acute self-limited colitis

World Journal of Gastroenterology

Volumn 16, Issue 5, 2010, Pages 583-587

  Sokol, Harry ^a   Vasquez, Nadia ^b   Hoyeau Idrissi, Nadia ^a   Seksik, Philippe ^a   Beaugerie, Laurent ^a   Lavergne Slove, Anne ^c   Pochart, Philippe ^b   Marteau, Philippe ^b,c  

^a HÔPITAL SAINT ANTOINE   (France)

^b Bioinformatique et Chimie Moléculaire   (France)

^c HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Crohn's disease; Crypt abscess; Inflammatory bowel diseases; Microbiota; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; CORTICOSTEROID; INFLIXIMAB; MESALAZINE;

ABSCESS; ACUTE SELF LIMITED COLITIS; ADULT; ARTICLE; BACTERIUM COLONY; BACTERIUM DETECTION; BACTEROIDES; CANCER SCREENING; CLINICAL ARTICLE; CLOSTRIDIUM; COLITIS; COLON BIOPSY; COLON CANCER; COLON FLORA; COLONOSCOPY; CONTROLLED STUDY; CROHN DISEASE; CRYPT ABSCESS; ENTEROBACTERIACEAE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; INTESTINE INJURY; MALE; MICROBIAL COMMUNITY; ULCERATIVE COLITIS;

EID: 76549112175     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i5.583     Document Type: Article

References (24)

1. Seksik P, Sokol H, Lepage P, Vasquez N, Manichanh C, Mangin I, Pochart P, Doré J, Marteau P. Review article: the role of bacteria in onset and perpetuation of inflammatory bowel disease. Aliment Pharmacol Ther 2006; 24 Suppl 3: 11-18
2. Lepage P, Seksik P, Sutren M, de la Cochetière MF, Jian R, Marteau P, Doré J. Biodiversity of the mucosa-associated microbiota is stable along the distal digestive tract in healthy individuals and patients with IBD. Inflamm Bowel Dis 2005; 11: 473-480
3. Sokol H, Lay C, Seksik P, Tannock GW. Analysis of bacterial bowel communities of IBD patients: what has it revealed? Inflamm Bowel Dis 2008; 14: 858-867
4. Lepage P, Seksik P, De La Cochetiere MF, Sutren M, Marteau P, Jian R, Dore J. Molecular study of the ileal and colonic mucosa associated flora in IBD. Gastroenterology 2003; 124: A477-A478
5. Seksik P, Lepage P, de la Cochetière MF, Bourreille A, Sutren M, Galmiche JP, Doré J, Marteau P. Search for localized dysbiosis in Crohn's disease ulcerations by temporal temperature gradient gel electrophoresis of 16S rRNA. J Clin Microbiol 2005; 43: 4654-4658
6. Seksik P, Rigottier-Gois L, Gramet G, Sutren M, Pochart P, Marteau P, Jian R, Doré J. Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut 2003; 52: 237-242
7. Sokol H, Lepage P, Seksik P, Doré J, Marteau P. Temperature gradient gel electrophoresis of fecal 16S rRNA reveals active Escherichia coli in the microbiota of patients with ulcerative colitis. J Clin Microbiol 2006; 44: 3172-3177
8. Sokol H, Seksik P, Rigottier-Gois L, Lay C, Lepage P, Podglajen I, Marteau P, Doré J. Specificities of the fecal microbiota in inflammatory bowel disease. Inflamm Bowel Dis 2006; 12: 106-111
9. Manichanh C, Rigottier-Gois L, Bonnaud E, Gloux K, Pelletier E, Frangeul L, Nalin R, Jarrin C, Chardon P, Marteau P, Roca J, Dore J. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut 2006; 55: 205-211
10. Sokol H, Lepage P, Seksik P, Doré J, Marteau P. Molecular comparison of dominant microbiota associated with injured versus healthy mucosa in ulcerative colitis. Gut 2007; 56: 152-154
11. Le Berre N, Heresbach D, Kerbaol M, Caulet S, Bretagne JF, Chaperon J, Gosselin M, Ramée MP. Histological discrimination of idiopathic inflammatory bowel disease from other types of colitis. J Clin Pathol 1995; 48: 749-753
12. Kumar NB, Nostrant TT, Appelman HD. The histopathologic spectrum of acute self-limited colitis (acute infectious-type colitis). Am J Surg Pathol 1982; 6: 523-529
13. Ayata G, Ithamukkala S, Sapp H, Shaz BH, Brien TP, Wang HH, Antonioli DA, Farraye FA, Odze RD. Prevalence and significance of inflammatory bowel disease-like morphologic features in collagenous and lymphocytic colitis. Am J Surg Pathol 2002; 26: 1414-1423
14. West AB, Losada M. The pathology of diverticulosis coli. J Clin Gastroenterol 2004; 38: S11-S16
15. Komorowski RA. Histologic spectrum of diversion colitis. Am J Surg Pathol 1990; 14: 548-554
16. Wehkamp J, Harder J, Weichenthal M, Mueller O, Herrlinger KR, Fellermann K, Schroeder JM, Stange EF. Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis. Inflamm Bowel Dis 2003; 9: 215-223
17. Wehkamp J, Harder J, Weichenthal M, Schwab M, Schäffeler E, Schlee M, Herrlinger KR, Stallmach A, Noack F, Fritz P, Schröder JM, Bevins CL, Fellermann K, Stange EF. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut 2004; 53: 1658-1664
18. Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H Jr, Fellermann K, Ganz T, Stange EF, Bevins CL. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci USA 2005; 102: 18129-18134
19. Wehkamp J, Schmid M, Stange EF. Defensins and other antimicrobial peptides in inflammatory bowel disease. Curr Opin Gastroenterol 2007; 23: 370-378
20. Fahlgren A, Hammarstrom S, Danielsson A, Hammarstrom ML. beta-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis. Clin Exp Immunol 2004; 137: 379-385
21. Vasquez N, Mangin I, Lepage P, Seksik P, Duong JP, Blum S, Schiffrin E, Suau A, Allez M, Vernier G, Tréton X, Doré J, Marteau P, Pochart P. Patchy distribution of mucosal lesions in ileal Crohn's disease is not linked to differences in the dominant mucosa-associated bacteria: a study using fluorescence in situ hybridization and temporal temperature gradient gel electrophoresis. Inflamm Bowel Dis 2007; 13: 684-692
22. Swidsinski A, Weber J, Loening-Baucke V, Hale LP, Lochs H. Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol 2005; 43: 3380-3389
23. Braat H, McGuirk P, Ten Kate FJ, Huibregtse I, Dunne PJ, Hommes DW, Van Deventer SJ, Mills KH. Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule. Gut 2007; 56: 351-357
24. Fallon PG, Alcami A. Pathogen-derived immunomodulatory molecules: future immunotherapeutics? Trends Immunol 2006; 27: 470-476