메뉴 건너뛰기




Volumn 585, Issue 23, 2011, Pages 3649-3659

Effector T cells in rheumatoid arthritis: Lessons from animal models

Author keywords

Animal model; Rheumatoid arthritis; T cell; T H1; T H17; T reg

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 4; PROTEIN KINASE ZAP 70;

EID: 81755172046     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.04.034     Document Type: Review
Times cited : (69)

References (181)
  • 1
    • 0016815881 scopus 로고
    • Predominantly T-cell infiltrate in rheumatoid synovial membranes
    • 10.1056/NEJM197509112931101
    • J.A. Van Boxel, and S.A. Paget Predominantly T-cell infiltrate in rheumatoid synovial membranes N. Engl. J. Med. 293 1975 517 520 10.1056/NEJM197509112931101
    • (1975) N. Engl. J. Med. , vol.293 , pp. 517-520
    • Van Boxel, J.A.1    Paget, S.A.2
  • 2
    • 0022495426 scopus 로고
    • Proliferative responses to T-cell lines grown from joint fluid of patients with rheumatoid arthritis and other arthritides
    • A.N. Abdel-Nour, C.J. Elson, and P.A. Dieppe Proliferative responses of T-cell lines grown from joint fluids of patients with rheumatoid arthritis and other arthritides Immunol. Lett. 12 1986 329 333 (Pubitemid 16082151)
    • (1986) Immunology Letters , vol.12 , Issue.5-6 , pp. 329-333
    • Abdel-Nour, A.N.1    Elson, C.J.2    Dieppe, P.A.3
  • 3
    • 0024314660 scopus 로고
    • + cells isolated from synovial fluid of patients with rheumatoid arthritis and other arthritides
    • DOI 10.1111/j.1365-3083.1989.tb01168.x
    • J. Hovdenes, G. Gaudernack, T.K. Kvien, T. Egeland, and O.J. Mellbye A functional study of purified CD4+ and CD8+ cells isolated from synovial fluid of patients with rheumatoid arthritis and other arthritides Scand. J. Immunol. 29 1989 641 649 (Pubitemid 19160938)
    • (1989) Scandinavian Journal of Immunology , vol.29 , Issue.6 , pp. 641-649
    • Hovdenes, J.1    Gaudernack, G.2    Kvien, T.K.3    Egeland, T.4    Mellbye, O.J.5
  • 4
    • 0030606310 scopus 로고    scopus 로고
    • Organ-specific disease provoked by systemic autoimmunity
    • DOI 10.1016/S0092-8674(00)81989-3
    • V. Kouskoff, A.-S. Korganow, V. Duchatelle, C. Degott, C. Benoist, and D. Mathis Organ-specific disease provoked by systemic autoimmunity Cell 87 1996 811 822 (Pubitemid 26404281)
    • (1996) Cell , vol.87 , Issue.5 , pp. 811-822
    • Kouskoff, V.1    Korganow, A.-S.2    Duchatelle, V.3    Degott, C.4    Benoist, C.5    Mathis, D.6
  • 6
    • 0025273129 scopus 로고
    • In vivo elimination of T cells expressing specific T-cell receptor Vβ chains in mice susceptible to collagen-induced arthritis
    • T.J. Goldschmidt, L. Jansson, and R. Holmdahl In vivo elimination of T cells expressing specific T-cell receptor V beta chains in mice susceptible to collagen-induced arthritis Immunology 69 1990 508 514 (Pubitemid 20123599)
    • (1990) Immunology , vol.69 , Issue.4 , pp. 508-514
    • Goldschmidt, T.J.1    Jansson, L.2    Holmdahl, R.3
  • 7
    • 0036604217 scopus 로고    scopus 로고
    • CD4 and CD8 T cells in susceptibility/protection to collagen-induced arthritis in HLA-DQ8-transgenic mice: Implications for rheumatoid arthritis
    • V. Taneja, N. Taneja, T. Paisansinsup, M. Behrens, M. Griffiths, H. Luthra, and C.S. David CD4 and CD8 T cells in susceptibility/protection to collagen-induced arthritis in HLA-DQ8-transgenic mice: implications for rheumatoid arthritis J. Immunol. 168 2002 5867 5875 (Pubitemid 34556175)
    • (2002) Journal of Immunology , vol.168 , Issue.11 , pp. 5867-5875
    • Taneja, V.1    Taneja, N.2    Paisansinsup, T.3    Behrens, M.4    Griffiths, M.5    Luthra, H.6    David, C.S.7
  • 8
    • 53149102866 scopus 로고    scopus 로고
    • Delineating the role of the HLA-DR4 "shared epitope" in susceptibility versus resistance to develop arthritis
    • doi: 181/4/2869
    • V. Taneja, M. Behrens, E. Basal, J. Sparks, M.M. Griffiths, H. Luthra, and C.S. David Delineating the role of the HLA-DR4 "shared epitope" in susceptibility versus resistance to develop arthritis J. Immunol. 181 2008 2869 2877 doi: 181/4/2869
    • (2008) J. Immunol. , vol.181 , pp. 2869-2877
    • Taneja, V.1    Behrens, M.2    Basal, E.3    Sparks, J.4    Griffiths, M.M.5    Luthra, H.6    David, C.S.7
  • 10
    • 33846207130 scopus 로고    scopus 로고
    • New humanized HLA-DR4-transgenic mice that mimic the sex bias of rheumatoid arthritis
    • DOI 10.1002/art.22213
    • V. Taneja, M. Behrens, A. Mangalam, M.M. Griffiths, H.S. Luthra, and C.S. David New humanized HLA-DR4-transgenic mice that mimic the sex bias of rheumatoid arthritis Arthritis Rheum. 56 2007 69 78 10.1002/art.22213 (Pubitemid 46110635)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 69-78
    • Taneja, V.1    Behrens, M.2    Mangalam, A.3    Griffiths, M.M.4    Luthra, H.S.5    David, C.S.6
  • 11
    • 0026111432 scopus 로고
    • The suppressive effect of HLA-DQw6 genes on collagen-induced arthritis in mice
    • T. Kawaharada The suppressive effect of HLA-DQw6 genes on collagen-induced arthritis in mice Fukuoka Igaku Zasshi 82 1991 71 85
    • (1991) Fukuoka Igaku Zasshi , vol.82 , pp. 71-85
    • Kawaharada, T.1
  • 13
    • 0030010969 scopus 로고    scopus 로고
    • + T cells play a role in initiation and regulate recovery phase of collagen-induced arthritis
    • Y. Tada, A. Ho, D.R. Koh, and T.W. Mak Collagen-induced arthritis in CD4- or CD8-deficient mice: CD8+ T cells play a role in initiation and regulate recovery phase of collagen-induced arthritis J. Immunol. 156 1996 4520 4526 (Pubitemid 26165856)
    • (1996) Journal of Immunology , vol.156 , Issue.11 , pp. 4520-4526
    • Tada, Y.1    Ho, A.2    Koh, D.-R.3    Mak, T.W.4
  • 14
    • 0031573090 scopus 로고    scopus 로고
    • Treatment of a Newly Established Transgenic Model of Chronic Arthritis with Nondepleting Anti-CD4 Monoclonal Antibody
    • C. Mauri, C.Q. Chu, D. Woodrow, L. Mori, and M. Londei Treatment of a newly established transgenic model of chronic arthritis with nondepleting anti-CD4 monoclonal antibody J. Immunol. 159 1997 5032 5041 (Pubitemid 127471042)
    • (1997) Journal of Immunology , vol.159 , Issue.10 , pp. 5032-5041
    • Mauri, C.1    Chu, C.-Q.Q.2    Woodrow, D.3    Mori, L.4    Londei, M.5
  • 15
    • 0024445315 scopus 로고
    • + T lymphocytes
    • R.O. Williams, A. Whyte, and H. Waldmann Resistance to collagen-induced arthritis in DBA/1 mice by intraperitoneal administration of soluble type II collagen involves both CD4+ and CD8+ T lymphocytes Autoimmunity 4 1989 237 245 (Pubitemid 19261055)
    • (1989) Autoimmunity , vol.4 , Issue.4 , pp. 237-245
    • Williams, R.O.1    Whyte, A.2    Waldmann, H.3
  • 16
    • 0026577173 scopus 로고
    • Depletion of alpha/beta T cells by a monoclonal antibody against the alpha/beta T cell receptor suppresses established adjuvant arthritis, but not established collagen-induced arthritis in rats
    • S. Yoshino, and L.G. Cleland Depletion of alpha/beta T cells by a monoclonal antibody against the alpha/beta T cell receptor suppresses established adjuvant arthritis, but not established collagen-induced arthritis in rats J. Exp. Med. 175 1992 907 915
    • (1992) J. Exp. Med. , vol.175 , pp. 907-915
    • Yoshino, S.1    Cleland, L.G.2
  • 17
    • 0028093246 scopus 로고
    • + T cells from collagen-induced arthritic mice are essential to transfer arthritis into severe combined immunodeficient mice
    • K.M. Kadowaki, H. Matsuno, H. Tsuji, and I. Tunru CD4+ T cells from collagen-induced arthritic mice are essential to transfer arthritis into severe combined immunodeficient mice Clin. Exp. Immunol. 97 1994 212 218 (Pubitemid 24263060)
    • (1994) Clinical and Experimental Immunology , vol.97 , Issue.2 , pp. 212-218
    • Kadowaki, K.M.1    Matsuno, H.2    Tsuji, H.3    Tunru, I.4
  • 18
    • 0030029609 scopus 로고    scopus 로고
    • Treatment with an anti-CD4 monoclonal antibody strongly ameliorates established rat adjuvant arthritis
    • C. Pelegri, M.P. Morante, C. Castellote, A. Franch, and M. Castell Treatment with an anti-CD4 monoclonal antibody strongly ameliorates established rat adjuvant arthritis Clin. Exp. Immunol. 103 1996 273 278 (Pubitemid 26046592)
    • (1996) Clinical and Experimental Immunology , vol.103 , Issue.2 , pp. 273-278
    • Pelegri, C.1    Morante, M.P.2    Castellote, C.3    Franch, A.4    Castell, M.5
  • 19
    • 0028856925 scopus 로고
    • Administration of a nondepleting anti-CD4 monoclonal antibody (W3/25) prevents adjuvant arthritis, even upon rechallenge: Parallel administration of a depleting anti-CD8 monoclonal antibody (OX8) does not modify the effect of W3/25
    • doi: S0008874985712038
    • C. Pelegri, M. Paz Morante, C. Castellote, M. Castell, and A. Franch Administration of a nondepleting anti-CD4 monoclonal antibody (W3/25) prevents adjuvant arthritis, even upon rechallenge: parallel administration of a depleting anti-CD8 monoclonal antibody (OX8) does not modify the effect of W3/25 Cell. Immunol. 165 1995 177 182 doi: S0008874985712038
    • (1995) Cell. Immunol. , vol.165 , pp. 177-182
    • Pelegri, C.1    Paz Morante, M.2    Castellote, C.3    Castell, M.4    Franch, A.5
  • 20
    • 0030587190 scopus 로고    scopus 로고
    • Induction of Th2 Cytokines and Control of Collagen-Induced Arthritis by Nondepleting Anti-CD4 Abs
    • C.Q. Chu, and M. Londei Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs J. Immunol. 157 1996 2685 2689 (Pubitemid 126450486)
    • (1996) Journal of Immunology , vol.157 , Issue.6 , pp. 2685-2689
    • Chu, C.-Q.1    Londei, M.2
  • 21
    • 0026515954 scopus 로고
    • Treatment of rats with monoclonal anti-CD4 induces long-term resistance to streptococcal cell wall-induced arthritis
    • 10.1002/eji.1830220110
    • M.F. Van den Broek, L.G. Van de Langerijt, M.C. Van Bruggen, M.E. Billingham, and W.B. Van den Berg Treatment of rats with monoclonal anti-CD4 induces long-term resistance to streptococcal cell wall-induced arthritis Eur. J. Immunol. 22 1992 57 61 10.1002/eji.1830220110
    • (1992) Eur. J. Immunol. , vol.22 , pp. 57-61
    • Van Den Broek, M.F.1    Van De Langerijt, L.G.2    Van Bruggen, M.C.3    Billingham, M.E.4    Van Den Berg, W.B.5
  • 22
    • 21644479222 scopus 로고    scopus 로고
    • Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin
    • 10.1186/ar1733 795
    • K. Raza, F. Falciani, S.J. Curnow, E.J. Ross, C.Y. Lee, A.N. Akbar, J.M. Lord, C. Gordon, C.D. Buckley, and M. Salmon Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin Arthritis Res. Ther. 7 2005 R784 R 795 10.1186/ar1733
    • (2005) Arthritis Res. Ther. , vol.7
    • Raza, K.1    Falciani, F.2    Curnow, S.J.3    Ross, E.J.4    Lee, C.Y.5    Akbar, A.N.6    Lord, J.M.7    Gordon, C.8    Buckley, C.D.9    Salmon, M.10
  • 25
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • DOI 10.1084/jem.20061308
    • S.C. Liang, X.Y. Tan, D.P. Luxenberg, R. Karim, K. Dunussi-Joannopoulos, M. Collins, and L.A. Fouser Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides J. Exp. Med. 203 2006 2271 2279 10.1084/jem.20061308 (Pubitemid 44498362)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.10 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.-Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6    Fouser, L.A.7
  • 26
    • 66049151440 scopus 로고    scopus 로고
    • Th17 and natural Treg cell population dynamics in systemic lupus erythematosus
    • 10.1002/art.24499
    • J. Yang, Y. Chu, X. Yang, D. Gao, L. Zhu, L. Wan, and M. Li Th17 and natural Treg cell population dynamics in systemic lupus erythematosus Arthritis Rheum. 60 2009 1472 1483 10.1002/art.24499
    • (2009) Arthritis Rheum. , vol.60 , pp. 1472-1483
    • Yang, J.1    Chu, Y.2    Yang, X.3    Gao, D.4    Zhu, L.5    Wan, L.6    Li, M.7
  • 27
    • 34247523141 scopus 로고    scopus 로고
    • Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation
    • DOI 10.1146/annurev.immunol.22.012703.104758
    • R.A. Kastelein, C.A. Hunter, and D.J. Cua Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation Annu. Rev. Immunol. 25 2007 221 242 10.1146/annurev.immunol.22.012703.104758 (Pubitemid 46697908)
    • (2007) Annual Review of Immunology , vol.25 , pp. 221-242
    • Kastelein, R.A.1    Hunter, C.A.2    Cua, D.J.3
  • 29
    • 0017657009 scopus 로고
    • Autoimmunity to type II collagen: an experimental model of arthritis
    • DOI 10.1084/jem.146.3.857
    • D.E. Trentham, A.S. Townes, and A.H. Kang Autoimmunity to type II collagen an experimental model of arthritis J. Exp. Med. 146 1977 857 868 (Pubitemid 8175993)
    • (1977) Journal of Experimental Medicine , vol.146 , Issue.3 , pp. 857-868
    • Trentham, D.E.1    Townes, A.S.2    Kang, A.H.3
  • 31
    • 0019512029 scopus 로고
    • Type II collagen-induced arthritis in mice I. Major histocompatibility complex (I region) linkage and antibody correlates
    • DOI 10.1084/jem.154.3.688
    • P.H. Wooley, H.S. Luthra, J.M. Stuart, and C.S. David Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates J. Exp. Med. 154 1981 688 700 (Pubitemid 11060781)
    • (1981) Journal of Experimental Medicine , vol.154 , Issue.3 , pp. 688-700
    • Wooley, P.H.1    Luthra, H.S.2    Stuart, J.M.3    David, C.S.4
  • 32
    • 0030905656 scopus 로고    scopus 로고
    • Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen-induced arthritis
    • DOI 10.1002/eji.1830270623
    • A. Doncarli, L.M. Stasiuk, C. Fournier, and O. Abehsira-Amar Conversion in vivo from an early dominant Th0/Th1 response to a Th2 phenotype during the development of collagen-induced arthritis Eur. J. Immunol. 27 1997 1451 1458 10.1002/eji.1830270623 (Pubitemid 27254838)
    • (1997) European Journal of Immunology , vol.27 , Issue.6 , pp. 1451-1458
    • Doncarli, A.1    Stasiuk, L.M.2    Fournier, C.3    Abehsira-Amar, O.4
  • 33
    • 0023905174 scopus 로고
    • Isolation of T cell line capable of protecting mice against collagen-induced arthritis
    • K. Kakimoto, M. Katsuki, T. Hirofuji, H. Iwata, and T. Koga Isolation of T cell line capable of protecting mice against collagen-induced arthritis J. Immunol. 140 1988 78 83 (Pubitemid 18050684)
    • (1988) Journal of Immunology , vol.140 , Issue.1 , pp. 78-83
    • Kakimoto, K.1    Katsuki, M.2    Hirofuji, T.3    Iwata, H.4    Koga, T.5
  • 34
    • 0033607499 scopus 로고    scopus 로고
    • Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
    • I. Matsumoto, A. Staub, C. Benoist, and D. Mathis Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme Science 286 1999 1732 1735 doi: 8037 (Pubitemid 129515879)
    • (1999) Science , vol.286 , Issue.5445 , pp. 1732-1735
    • Matsumoto, I.1    Staub, A.2    Benoist, C.3    Mathis, D.4
  • 35
    • 0036230130 scopus 로고    scopus 로고
    • How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease
    • DOI 10.1038/ni772
    • I. Matsumoto, M. Maccioni, D.M. Lee, M. Maurice, B. Simmons, M. Brenner, D. Mathis, and C. Benoist How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease Nat. Immunol. 3 2002 360 365 10.1038/ni772 (Pubitemid 34308624)
    • (2002) Nature Immunology , vol.3 , Issue.4 , pp. 360-365
    • Matsumoto, I.1    Maccioni, M.2    Lee, D.M.3    Maurice, M.4    Simmons, B.5    Brenner, M.6    Mathis, D.7    Benoist, C.8
  • 36
    • 0001422157 scopus 로고
    • Passive transfer of adjuvant arthritis by lymph node or spleen cells
    • C.M. Pearson, and F.D. Wood Passive transfer of adjuvant arthritis by lymph node or spleen cells J. Exp. Med. 120 1964 547 560
    • (1964) J. Exp. Med. , vol.120 , pp. 547-560
    • Pearson, C.M.1    Wood, F.D.2
  • 37
    • 0022460311 scopus 로고
    • T lymphocyte-dependent evolution of bacterial cell wall-induced hepatic granulomas
    • S.M. Wahl, J.B. Allen, S. Dougherty, V. Evequoz, D.H. Pluznik, R.L. Wilder, A.R. Hand, and L.M. Wahl T lymphocyte-dependent evolution of bacterial cell wall-induced hepatic granulomas J. Immunol. 137 1986 2199 2209 (Pubitemid 16020712)
    • (1986) Journal of Immunology , vol.137 , Issue.7 , pp. 2199-2209
    • Wahl, S.M.1    Allen, J.B.2    Dougherty, S.3
  • 38
    • 0020515564 scopus 로고
    • The cellular basis of adjuvant arthritis. II. Characterization of the cells mediating passive transfer
    • J.D. Taurog, G.P. Sandberg, and M.L. Mahowald The cellular basis of adjuvant arthritis. II. Characterization of the cells mediating passive transfer Cell. Immunol. 80 1983 198 204 (Pubitemid 13050206)
    • (1983) Cellular Immunology , vol.80 , Issue.1 , pp. 198-204
    • Taurog, J.D.1    Sandberg, G.P.2    Mahowald, M.L.3
  • 40
    • 77956413981 scopus 로고    scopus 로고
    • Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice
    • 10.1371/journal.pone.0010558
    • J. Duarte, A. Agua-Doce, V.G. Oliveira, J.E. Fonseca, and L. Graca Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice PLoS ONE 5 2010 e10558 10.1371/journal.pone.0010558
    • (2010) PLoS ONE , vol.5 , pp. 10558
    • Duarte, J.1    Agua-Doce, A.2    Oliveira, V.G.3    Fonseca, J.E.4    Graca, L.5
  • 42
    • 77954315823 scopus 로고    scopus 로고
    • Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model
    • doi:10.1016/j.clim.2010.03.428 doi: S1521-6616(10)00528-0
    • Tsunemi S, Iwasaki T, Kitano S, Imado T, Miyazawa K & Sano H. Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model. Clin. Immunol. 136, 197-204, doi: S1521-6616(10)00528-0, doi: 10.1016/j.clim.2010.03.428.
    • Clin. Immunol. , vol.136 , pp. 197-204
    • Tsunemi, S.1    Iwasaki, T.2    Kitano, S.3    Imado, T.4    Miyazawa, K.5    Sano, H.6
  • 43
    • 79951833594 scopus 로고    scopus 로고
    • SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice
    • 10.4049/jimmunol.1003601
    • L.K. Peterson, L.A. Shaw, A. Joetham, S. Sakaguchi, E.W. Gelfand, and L.L. Dragone SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice J. Immunol. 186 2011 2273 2281 10.4049/jimmunol.1003601
    • (2011) J. Immunol. , vol.186 , pp. 2273-2281
    • Peterson, L.K.1    Shaw, L.A.2    Joetham, A.3    Sakaguchi, S.4    Gelfand, E.W.5    Dragone, L.L.6
  • 44
    • 77956894327 scopus 로고    scopus 로고
    • Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function
    • 10.4049/jimmunol.1000848
    • S. Tanaka, S. Maeda, M. Hashimoto, C. Fujimori, Y. Ito, S. Teradaira, K. Hirota, H. Yoshitomi, T. Katakai, and A. Shimizu Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function J. Immunol. 185 2010 2295 2305 10.4049/jimmunol.1000848
    • (2010) J. Immunol. , vol.185 , pp. 2295-2305
    • Tanaka, S.1    Maeda, S.2    Hashimoto, M.3    Fujimori, C.4    Ito, Y.5    Teradaira, S.6    Hirota, K.7    Yoshitomi, H.8    Katakai, T.9    Shimizu, A.10
  • 45
    • 0038603018 scopus 로고    scopus 로고
    • Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis
    • DOI 10.1093/rheumatology/keg262
    • A.P. Cope Exploring the reciprocal relationship between immunity and inflammation in chronic inflammatory arthritis Rheumatology (Oxford) 42 2003 716 731 10.1093/rheumatology/keg262 (Pubitemid 37220902)
    • (2003) Rheumatology , vol.42 , Issue.6 , pp. 716-731
    • Cope, A.P.1
  • 47
    • 0032532596 scopus 로고    scopus 로고
    • Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: Evidence for genetic factors common to multiple autoimmune diseases
    • Y. Kawahito, G.W. Cannon, P.S. Gulko, E.F. Remmers, R.E. Longman, V.R. Reese, J. Wang, M.M. Griffiths, and R.L. WilDer Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: evidence for genetic factors common to multiple autoimmune diseases J. Immunol. 161 1998 4411 4419 (Pubitemid 28469028)
    • (1998) Journal of Immunology , vol.161 , Issue.8 , pp. 4411-4419
    • Kawahito, Y.1    Cannon, G.W.2    Gulko, P.S.3    Remmers, E.F.4    Longman, R.E.5    Reese, V.R.6    Wang, J.7    Griffiths, M.M.8    WilDer, R.L.9
  • 48
    • 0036222782 scopus 로고    scopus 로고
    • Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: Identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci
    • DOI 10.1002/art.10164
    • B. Joe, G.W. Cannon, M.M. Griffiths, D.E. Dobbins, P.S. Gulko, R.L. Wilder, and E.F. Remmers Evaluation of quantitative trait loci regulating severity of mycobacterial adjuvant-induced arthritis in monocongenic and polycongenic rats: identification of a new regulatory locus on rat chromosome 10 and evidence of overlap with rheumatoid arthritis susceptibility loci Arthritis Rheum. 46 2002 1075 1085 10.1002/art.10164 (Pubitemid 34303822)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.4 , pp. 1075-1085
    • Joe, B.1    Cannon, G.W.2    Griffiths, M.M.3    Dobbins, D.E.4    Gulko, P.S.5    WilDer, R.L.6    Remmers, E.F.7
  • 50
    • 0020684764 scopus 로고
    • Lines of T lymphocytes induce or vaccinate against autoimmune arthritis
    • J. Holoshitz, Y. Naparstek, A. Ben-Nun, and I.R. Cohen Lines of T lymphocytes induce or vaccinate against autoimmune arthritis Science 219 1983 56 58 (Pubitemid 13204148)
    • (1983) Science , vol.219 , Issue.4580 , pp. 56-58
    • Holoshitz, J.1    Naparstek, Y.2    Ben-Nun, A.3    Cohen, I.R.4
  • 51
    • 0021335515 scopus 로고
    • Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II
    • J. Holoshitz, A. Matitiau, and I.R. Cohen Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II J. Clin. Invest. 73 1984 211 215 10.1172/JCI111193 (Pubitemid 14222664)
    • (1984) Journal of Clinical Investigation , vol.73 , Issue.1 , pp. 211-215
    • Holoshitz, J.1    Matitiau, A.2    Cohen, I.R.3
  • 53
    • 0026770364 scopus 로고
    • Arthritis induced in rats with adjuvant oil is a genetically restricted, alpha beta T-cell dependent autoimmune disease
    • R. Holmdahl, T.J. Goldschmidt, S. Kleinau, C. Kvick, and R. Jonsson Arthritis induced in rats with adjuvant oil is a genetically restricted, alpha beta T-cell dependent autoimmune disease Immunology 76 1992 197 202
    • (1992) Immunology , vol.76 , pp. 197-202
    • Holmdahl, R.1    Goldschmidt, T.J.2    Kleinau, S.3    Kvick, C.4    Jonsson, R.5
  • 54
    • 0020068416 scopus 로고
    • Epithelioid granuloma formation requiring no T-cell function
    • A. Tanaka, K. Emori, S. Nagao, K. Kushima, O. Kohashi, M. Saitoh, and T. Kataoka Epithelioid granuloma formation requiring no T-cell function Am. J. Pathol. 106 1982 165 170 (Pubitemid 12172158)
    • (1982) American Journal of Pathology , vol.106 , Issue.2 , pp. 165-170
    • Tanaka, A.1    Emori, K.2    Nagao, S.3
  • 55
    • 57349104041 scopus 로고    scopus 로고
    • Increased number and function of FoxP3 regulatory T cells during experimental arthritis
    • 10.1002/art.24048
    • K. Monte, C. Wilson, and F.F. Shih Increased number and function of FoxP3 regulatory T cells during experimental arthritis Arthritis Rheum. 58 2008 3730 3741 10.1002/art.24048
    • (2008) Arthritis Rheum. , vol.58 , pp. 3730-3741
    • Monte, K.1    Wilson, C.2    Shih, F.F.3
  • 58
    • 0031913238 scopus 로고    scopus 로고
    • Common commercial cosmetic products induce arthritis in the DA rat
    • B. Sverdrup, L. Klareskog, and S. Kleinau Common commercial cosmetic products induce arthritis in the DA rat Environ. Health Perspect. 106 1998 27 32 (Pubitemid 28122014)
    • (1998) Environmental Health Perspectives , vol.106 , Issue.1 , pp. 27-32
    • Sverdrup, B.1    Klareskog, L.2    Kleinau, S.3
  • 59
    • 0025306842 scopus 로고
    • Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice
    • DOI 10.1002/art.1780330614
    • K. Mikecz, T.T. Glant, E. Buzas, and A.R. Poole Proteoglycan-induced polyarthritis and spondylitis adoptively transferred to naive (nonimmunized) BALB/c mice Arthritis Rheum. 33 1990 866 876 (Pubitemid 20205767)
    • (1990) Arthritis and Rheumatism , vol.33 , Issue.6 , pp. 866-876
    • Mikecz, K.1    Glant, T.T.2    Buzas, E.3    Poole, A.R.4
  • 60
    • 0026446525 scopus 로고
    • The induction of arthritis in mice by the cartilage proteoglycan aggrecan: Roles of CD4+ and CD8+ T cells
    • S. Banerjee, C. Webber, and A.R. Poole The induction of arthritis in mice by the cartilage proteoglycan aggrecan: roles of CD4+ and CD8+ T cells Cell. Immunol. 144 1992 347 357
    • (1992) Cell. Immunol. , vol.144 , pp. 347-357
    • Banerjee, S.1    Webber, C.2    Poole, A.R.3
  • 62
    • 1642342306 scopus 로고    scopus 로고
    • Immunization with Glucose-6-Phosphate Isomerase Induces T Cell-Dependent Peripheral Polyarthritis in Genetically Unaltered Mice
    • D. Schubert, B. Maier, L. Morawietz, V. Krenn, and T. Kamradt Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice J. Immunol. 172 2004 4503 4509 (Pubitemid 38375267)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4503-4509
    • Schubert, D.1    Maier, B.2    Morawietz, L.3    Krenn, V.4    Kamradt, T.5
  • 63
    • 1542329511 scopus 로고    scopus 로고
    • Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen-induced arthritis: Influence on T helper cell activation
    • DOI 10.1111/j.1365-2249.2003.02381.x
    • D. Pohlers, K. Nissler, O. Frey, J. Simon, P.K. Petrow, R.W. Kinne, and R. Brauer Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen-induced arthritis: influence on T helper cell activation Clin. Exp. Immunol. 135 2004 409 415 doi: 2381 (Pubitemid 38297140)
    • (2004) Clinical and Experimental Immunology , vol.135 , Issue.3 , pp. 409-415
    • Pohlers, D.1    Nissler, K.2    Frey, O.3    Simon, J.4    Petrow, P.K.5    Kinne, R.W.6    Brauer, R.7
  • 64
    • 7244242322 scopus 로고    scopus 로고
    • Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen induced arthritis: Influence on macrophage activation
    • DOI 10.1136/ard.2003.013060
    • K. Nissler, D. Pohlers, M. Huckel, J. Simon, R. Brauer, and R.W. Kinne Anti-CD4 monoclonal antibody treatment in acute and early chronic antigen induced arthritis: influence on macrophage activation Ann. Rheum. Dis. 63 2004 1470 1477 doi: 63/11/1470 [pii], doi: 10.1136/ard.2003.013060 (Pubitemid 39433953)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.11 , pp. 1470-1477
    • Nissler, K.1    Pohlers, D.2    Huckel, M.3    Simon, J.4    Brauer, R.5    Kinne, R.W.6
  • 66
    • 0029921352 scopus 로고    scopus 로고
    • Increased expression of interferon (IFN)-gamma together with IFN-gamma receptor in the rheumatoid synovial membrane compared with synovium of patients with osteoarthritis
    • R.J. Dolhain, N.T. ter Haar, S. Hoefakker, P.P. Tak, M. de Ley, E. Claassen, F.C. Breedveld, and A.M. Miltenburg Increased expression of interferon (IFN)-gamma together with IFN-gamma receptor in the rheumatoid synovial membrane compared with synovium of patients with osteoarthritis Br. J. Rheumatol. 35 1996 24 32
    • (1996) Br. J. Rheumatol. , vol.35 , pp. 24-32
    • Dolhain, R.J.1    Ter Haar, N.T.2    Hoefakker, S.3    Tak, P.P.4    De Ley, M.5    Claassen, E.6    Breedveld, F.C.7    Miltenburg, A.M.8
  • 67
    • 0031880402 scopus 로고    scopus 로고
    • Analysis of type 1 and type 2 T cells in synovial fluid and peripheral blood of patients with rheumatoid arthritis
    • M. Kusaba, J. Honda, T. Fukuda, and K. Oizumi Analysis of type 1 and type 2 T cells in synovial fluid and peripheral blood of patients with rheumatoid arthritis J. Rheumatol. 25 1998 1466 1471 (Pubitemid 28364747)
    • (1998) Journal of Rheumatology , vol.25 , Issue.8 , pp. 1466-1471
    • Kusaba, M.1    Honda, J.2    Fukuda, T.3    Oizumi, K.4
  • 68
    • 0031656139 scopus 로고    scopus 로고
    • Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis
    • DOI 10.1002/1529-0131(199809)41:9<1669::AID-ART19>3.0.CO;2-G
    • Y. Morita, M. Yamamura, M. Kawashima, S. Harada, K. Tsuji, K. Shibuya, K. Maruyama, and H. Makino Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis Arthritis Rheum. 41 1998 1669 1676 doi: 10.1002/1529-0131(199809)41:9<1669::AID-ART19>3.0.CO;2-G (Pubitemid 28459927)
    • (1998) Arthritis and Rheumatism , vol.41 , Issue.9 , pp. 1669-1676
    • Morita, Y.1    Yamamura, M.2    Kawashima, M.3    Harada, S.4    Tsuji, K.5    Shibuya, K.6    Maruyama, K.7    Makino, H.8
  • 69
    • 0034468153 scopus 로고    scopus 로고
    • + memory T cells in rheumatoid arthritis synovium
    • DOI 10.1186/ar120
    • T. Nanki, and P.E. Lipsky Cytokine, activation marker, and chemokine receptor expression by individual CD4(+) memory T cells in rheumatoid arthritis synovium Arthritis Res. 2 2000 415 423 (Pubitemid 32223780)
    • (2000) Arthritis Research , vol.2 , Issue.5 , pp. 415-423
    • Nanki, T.1    Lipsky, P.E.2
  • 72
    • 75649140602 scopus 로고    scopus 로고
    • Regulation of pathogenic IL-17 responses in collagen-induced arthritis: Roles of endogenous interferon-gamma and IL-4
    • 10.1186/ar2838
    • S. Sarkar, L.A. Cooney, P. White, D.B. Dunlop, J. Endres, J.M. Jorns, M.J. Wasco, and D.A. Fox Regulation of pathogenic IL-17 responses in collagen-induced arthritis: roles of endogenous interferon-gamma and IL-4 Arthritis Res. Ther. 11 2009 R158 10.1186/ar2838
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 158
    • Sarkar, S.1    Cooney, L.A.2    White, P.3    Dunlop, D.B.4    Endres, J.5    Jorns, J.M.6    Wasco, M.J.7    Fox, D.A.8
  • 73
    • 0026030815 scopus 로고
    • IFN-gamma inhibits inflammatory cell recruitment and the evolution of bacterial cell wall-induced arthritis
    • S.M. Wahl, J.B. Allen, K. Ohura, D.E. Chenoweth, and A.R. Hand IFN-gamma inhibits inflammatory cell recruitment and the evolution of bacterial cell wall-induced arthritis J. Immunol. 146 1991 95 100
    • (1991) J. Immunol. , vol.146 , pp. 95-100
    • Wahl, S.M.1    Allen, J.B.2    Ohura, K.3    Chenoweth, D.E.4    Hand, A.R.5
  • 74
    • 0026128660 scopus 로고
    • Suppression of bacterial cell wall-induced polyarthritis by recombinant gamma interferon
    • doi: 1043-4666(91)90029-D
    • J.B. Allen, G.P. Bansal, G.M. Feldman, A.O. Hand, L.M. Wahl, and S.M. Wahl Suppression of bacterial cell wall-induced polyarthritis by recombinant gamma interferon Cytokine 3 1991 98 106 doi: 1043-4666(91)90029-D
    • (1991) Cytokine , vol.3 , pp. 98-106
    • Allen, J.B.1    Bansal, G.P.2    Feldman, G.M.3    Hand, A.O.4    Wahl, L.M.5    Wahl, S.M.6
  • 75
    • 38449089583 scopus 로고    scopus 로고
    • Exacerbation of antigen-induced arthritis in IFN-gamma-deficient mice as a result of unrestricted IL-17 response
    • doi: 179/9/6228
    • I.M. Irmler, M. Gajda, and R. Brauer Exacerbation of antigen-induced arthritis in IFN-gamma-deficient mice as a result of unrestricted IL-17 response J. Immunol. 179 2007 6228 6236 doi: 179/9/6228
    • (2007) J. Immunol. , vol.179 , pp. 6228-6236
    • Irmler, I.M.1    Gajda, M.2    Brauer, R.3
  • 76
    • 79951942586 scopus 로고    scopus 로고
    • Ameliorated course of glucose-6-phosphate isomerase (G6PI)-induced arthritis in IFN-gamma receptor knockout mice exposes an arthritis-promoting role of IFN-gamma
    • doi:10.1016/j.jaut.2010.12.006 doi: S0896-8411(10)00149-6
    • Frey O, Mitera T, Kelchtermans H, Schurgers E, Kamradt T & Matthys P Ameliorated course of glucose-6-phosphate isomerase (G6PI)-induced arthritis in IFN-gamma receptor knockout mice exposes an arthritis-promoting role of IFN-gamma. J. Autoimmun. 36, 161-169, doi: S0896-8411(10)00149-6, doi: 10.1016/j.jaut.2010.12.006.
    • J. Autoimmun. , vol.36 , pp. 161-169
    • Frey, O.1    Mitera, T.2    Kelchtermans, H.3    Schurgers, E.4    Kamradt, T.5    Matthys, P.6
  • 77
    • 0142103924 scopus 로고    scopus 로고
    • Dependence on Interferon-γ for the Spontaneous Occurrence of Arthritis in DBA/1 Mice
    • DOI 10.1002/art.11273
    • P. Matthys, R.J. Lories, B. De Klerck, H. Heremans, F.P. Luyten, and A. Billiau Dependence on interferon-gamma for the spontaneous occurrence of arthritis in DBA/1 mice Arthritis Rheum. 48 2003 2983 2988 10.1002/art.11273 (Pubitemid 37280629)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.10 , pp. 2983-2988
    • Matthys, P.1    Lories, R.J.2    De Klerck, B.3    Heremans, H.4    Luyten, F.P.5    Billiau, A.6
  • 79
    • 0029980268 scopus 로고    scopus 로고
    • Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis
    • DOI 10.1002/eji.1830260716
    • C. Mauri, R.O. Williams, M. Walmsley, and M. Feldmann Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis Eur. J. Immunol. 26 1996 1511 1518 10.1002/eji.1830260716 (Pubitemid 26229996)
    • (1996) European Journal of Immunology , vol.26 , Issue.7 , pp. 1511-1518
    • Mauri, C.1    Williams, R.O.2    Walmsley, M.3    Feldmann, M.4
  • 80
    • 0033959881 scopus 로고    scopus 로고
    • Characterization of the cytokine network at a single cell level in mice with collagen-induced arthritis using a dual color ELISPOT assay
    • DOI 10.1089/107999000312739
    • Y. Okamoto, Y. Gotoh, H. Tokui, A. Mizuno, Y. Kobayashi, and M. Nishida Characterization of the cytokine network at a single cell level in mice with collagen-induced arthritis using a dual color ELISPOT assay J. Interferon Cytokine Res. 20 2000 55 61 10.1089/107999000312739 (Pubitemid 30067489)
    • (2000) Journal of Interferon and Cytokine Research , vol.20 , Issue.1 , pp. 55-61
    • Okamoto, Y.1    Gotoh, Y.2    Tokui, H.3    Mizuno, A.4    Kobayashi, Y.5    Nishida, M.6
  • 82
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • doi: S1074-7613(00)00070-4
    • B. Oppmann, R. Lesley, B. Blom, J.C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, and K. Singh Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 2000 715 725 doi: S1074-7613(00)00070-4
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6    Vega, F.7    Yu, N.8    Wang, J.9    Singh, K.10
  • 86
    • 0030069075 scopus 로고    scopus 로고
    • High doses of interleukin-12 inhibit the development of joint disease in DBA/1 mice immunized with type II collagen in complete Freund's adjuvant
    • DOI 10.1002/eji.1830260129
    • H. Hess, M.K. Gately, E. Rude, E. Schmitt, J. Szeliga, and T. Germann High doses of interleukin-12 inhibit the development of joint disease in DBA/1 mice immunized with type II collagen in complete Freund's adjuvant Eur. J. Immunol. 26 1996 187 191 10.1002/eji.1830260129 (Pubitemid 26028432)
    • (1996) European Journal of Immunology , vol.26 , Issue.1 , pp. 187-191
    • Hess, H.1    Gately, M.K.2    Rude, E.3    Schmitt, E.4    Szeliga, J.5    Germann, T.6
  • 89
    • 38449102562 scopus 로고    scopus 로고
    • IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis
    • doi: 179/10/7128
    • Y. Yamaguchi, K. Fujio, H. Shoda, A. Okamoto, N.H. Tsuno, K. Takahashi, and K. Yamamoto IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis J. Immunol. 179 2007 7128 7136 doi: 179/10/7128
    • (2007) J. Immunol. , vol.179 , pp. 7128-7136
    • Yamaguchi, Y.1    Fujio, K.2    Shoda, H.3    Okamoto, A.4    Tsuno, N.H.5    Takahashi, K.6    Yamamoto, K.7
  • 90
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice
    • S. Nakae, A. Nambu, K. Sudo, and Y. Iwakura Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice J. Immunol. 171 2003 6173 6177 (Pubitemid 37467240)
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 91
    • 0038623916 scopus 로고    scopus 로고
    • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist
    • DOI 10.1073/pnas.1035999100
    • S. Nakae, S. Saijo, R. Horai, K. Sudo, S. Mori, and Y. Iwakura IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist Proc. Natl. Acad. Sci. USA 100 2003 5986 5990 10.1073/pnas.1035999100 (Pubitemid 36576918)
    • (2003) Proceedings of the National Academy of Sciences of the United States of America , vol.100 , Issue.10 , pp. 5986-5990
    • Nakae, S.1    Saijo, S.2    Horai, R.3    Sudo, K.4    Mori, S.5    Iwakura, Y.6
  • 93
    • 1042267236 scopus 로고    scopus 로고
    • Treatment with a Neutralizing Anti-Murine Interleukin-17 Antibody after the Onset of Collagen-Induced Arthritis Reduces Joint Inflammation, Cartilage Destruction, and Bone Erosion
    • DOI 10.1002/art.20001
    • E. Lubberts, M.I. Koenders, B. Oppers-Walgreen, L. Van den Bersselaar, C.J. Coenen-de Roo, L.A. Joosten, and W.B. Van den Berg Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion Arthritis Rheum. 50 2004 650 659 10.1002/art.20001 (Pubitemid 38198849)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 650-659
    • Lubberts, E.1    Koenders, M.I.2    Oppers-Walgreen, B.3    Van Den Bersselaar, L.4    Coenen-De Roo, C.J.J.5    Joosten, L.A.B.6    Van Den Berg, W.B.7
  • 94
    • 57349153093 scopus 로고    scopus 로고
    • Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis
    • 10.1002/art.24075
    • P.J. Egan, A. Van Nieuwenhuijze, I.K. Campbell, and I.P. Wicks Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis Arthritis Rheum. 58 2008 3720 3729 10.1002/art.24075
    • (2008) Arthritis Rheum. , vol.58 , pp. 3720-3729
    • Egan, P.J.1    Van Nieuwenhuijze, A.2    Campbell, I.K.3    Wicks, I.P.4
  • 95
    • 79151486080 scopus 로고    scopus 로고
    • Th17 cells can provide B cell help in autoantibody induced arthritis
    • doi:10.1016/j.jaut.2010.10.007 doi: S0896-8411(10)00139-3
    • Hickman-Brecks CL, Racz JL, Meyer DM, Labranche TP & Allen PM Th17 cells can provide B cell help in autoantibody induced arthritis. J. Autoimmun. 36, 65-75, doi: S0896-8411(10)00139-3, doi: 10.1016/j.jaut.2010.10.007.
    • J. Autoimmun. , vol.36 , pp. 65-75
    • Hickman-Brecks, C.L.1    Racz, J.L.2    Meyer, D.M.3    Labranche, T.P.4    Allen, P.M.5
  • 96
    • 0036188478 scopus 로고    scopus 로고
    • Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein
    • DOI 10.1002/art.10173
    • K.A. Bush, K.M. Farmer, J.S. Walker, and B.W. Kirkham Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein Arthritis Rheum. 46 2002 802 805 10.1002/art.10173 (Pubitemid 34214263)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.3 , pp. 802-805
    • Bush, K.A.1    Farmer, K.M.2    Walker, J.S.3    Kirkham, B.W.4
  • 97
    • 26844554064 scopus 로고    scopus 로고
    • Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis
    • DOI 10.1002/art.21342
    • M.I. Koenders, J.K. Kolls, B. Oppers-Walgreen, L. Van den Bersselaar, L.A. Joosten, J.R. Schurr, P. Schwarzenberger, W.B. Van den Berg, and E. Lubberts Interleukin-17 receptor deficiency results in impaired synovial expression of interleukin-1 and matrix metalloproteinases 3, 9, and 13 and prevents cartilage destruction during chronic reactivated streptococcal cell wall-induced arthritis Arthritis Rheum. 52 2005 3239 3247 10.1002/art.21342 (Pubitemid 41447107)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.10 , pp. 3239-3247
    • Koenders, M.I.1    Kolls, J.K.2    Oppers-Walgreen, B.3    Van Den Bersselaar, L.4    Joosten, L.A.B.5    Schurr, J.R.6    Schwarzenberger, P.7    Van Den Berg, W.B.8    Lubberts, E.9
  • 98
    • 26044455144 scopus 로고    scopus 로고
    • Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients
    • doi: 829
    • S.Y. Hwang, and H.Y. Kim Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients Mol. Cells 19 2005 180 184 doi: 829
    • (2005) Mol. Cells , vol.19 , pp. 180-184
    • Hwang, S.Y.1    Kim, H.Y.2
  • 99
    • 47949090745 scopus 로고    scopus 로고
    • Development of proteoglycan-induced arthritis is independent of IL-17
    • doi: 181/1/329
    • P.D. Doodes, Y. Cao, K.M. Hamel, Y. Wang, B. Farkas, Y. Iwakura, and A. Finnegan Development of proteoglycan-induced arthritis is independent of IL-17 J. Immunol. 181 2008 329 337 doi: 181/1/329
    • (2008) J. Immunol. , vol.181 , pp. 329-337
    • Doodes, P.D.1    Cao, Y.2    Hamel, K.M.3    Wang, Y.4    Farkas, B.5    Iwakura, Y.6    Finnegan, A.7
  • 104
    • 77950548359 scopus 로고    scopus 로고
    • Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis
    • doi:10.1002/art.27336
    • Mus AM, Cornelissen F, Asmawidjaja PS, Van Hamburg JP, Boon L, Hendriks RW & Lubberts E Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis. Arthritis Rheum. 62, 1043-1050. doi: 10.1002/art.27336.
    • Arthritis Rheum. , vol.62 , pp. 1043-1050
    • Mus, A.M.1    Cornelissen, F.2    Asmawidjaja, P.S.3    Van Hamburg, J.P.4    Boon, L.5    Hendriks, R.W.6    Lubberts, E.7
  • 106
    • 35348889009 scopus 로고    scopus 로고
    • + T cell response to produce IL-17
    • DOI 10.1002/eji.200737229
    • K. Yoshihara, H. Yamada, A. Hori, T. Yajima, C. Kubo, and Y. Yoshikai IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17 Eur. J. Immunol. 37 2007 2744 2752 10.1002/eji.200737229 (Pubitemid 47578293)
    • (2007) European Journal of Immunology , vol.37 , Issue.10 , pp. 2744-2752
    • Yoshihara, K.1    Yamada, H.2    Hori, A.3    Yajima, T.4    Kubo, C.5    Yoshikai, Y.6
  • 108
    • 57349156961 scopus 로고    scopus 로고
    • Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis
    • 10.1002/art.24072
    • S. Veenbergen, M.B. Bennink, A.S. de Hooge, O.J. Arntz, R.L. Smeets, W.B. Van den Berg, and F.A. Van de Loo Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen-induced arthritis Arthritis Rheum. 58 2008 3742 3752 10.1002/art.24072
    • (2008) Arthritis Rheum. , vol.58 , pp. 3742-3752
    • Veenbergen, S.1    Bennink, M.B.2    De Hooge, A.S.3    Arntz, O.J.4    Smeets, R.L.5    Van Den Berg, W.B.6    Van De Loo, F.A.7
  • 109
    • 77949653393 scopus 로고    scopus 로고
    • Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells
    • 10.1186/ar2893
    • F. Cornelissen, A.M. Mus, P.S. Asmawidjaja, J.P. Van Hamburg, J. Tocker, and E. Lubberts Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells Arthritis Res. Ther. 11 2009 R194 10.1186/ar2893
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 194
    • Cornelissen, F.1    Mus, A.M.2    Asmawidjaja, P.S.3    Van Hamburg, J.P.4    Tocker, J.5    Lubberts, E.6
  • 110
    • 78649526238 scopus 로고    scopus 로고
    • Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases
    • doi:10.1038/nri2889
    • Buckner JH Mechanisms of impaired regulation by CD4(+)CD25(+)FOXP3(+) regulatory T cells in human autoimmune diseases. Nat. Rev. Immunol. 10, 849-859. doi: 10.1038/nri2889.
    • Nat. Rev. Immunol. , vol.10 , pp. 849-859
    • Buckner, J.H.1
  • 111
    • 33847080383 scopus 로고    scopus 로고
    • Therapeutic effect of urocortin on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of regulatory T cells
    • 10.1002/art.22394
    • E. Gonzalez-Rey, A. Chorny, N. Varela, F. O'Valle, and M. Delgado Therapeutic effect of urocortin on collagen-induced arthritis by down-regulation of inflammatory and Th1 responses and induction of regulatory T cells Arthritis Rheum. 56 2007 531 543 10.1002/art.22394
    • (2007) Arthritis Rheum. , vol.56 , pp. 531-543
    • Gonzalez-Rey, E.1    Chorny, A.2    Varela, N.3    O'Valle, F.4    Delgado, M.5
  • 113
    • 75349112514 scopus 로고    scopus 로고
    • CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population
    • doi:10.1016/j.jaut.2009.07.006 doi: S0896-8411(09)00087-0
    • Ko HJ, Cho ML, Lee SY, Oh HJ, Heo YJ, Moon YM, Kang CM, Kwok SK, Ju JH, Park SH, et al. CTLA4-Ig modifies dendritic cells from mice with collagen-induced arthritis to increase the CD4+CD25+Foxp3+ regulatory T cell population. J. Autoimmun. 34, 111-120, doi: S0896-8411(09)00087-0, doi: 10.1016/j.jaut.2009.07.006.
    • J. Autoimmun. , vol.34 , pp. 111-120
    • Ko, H.J.1    Cho, M.L.2    Lee, S.Y.3    Oh, H.J.4    Heo, Y.J.5    Moon, Y.M.6    Kang, C.M.7    Kwok, S.K.8    Ju, J.H.9    Park, S.H.10
  • 114
    • 58249113108 scopus 로고    scopus 로고
    • Construction and characterization of a novel DNA vaccine that is potent antigen-specific tolerizing therapy for experimental arthritis by increasing CD4+CD25+Treg cells and inducing Th1 to Th2 shift in both cells and cytokines
    • doi: S0264-410X(08)01572-7
    • X. Song, F. Liang, N. Liu, Y. Luo, H. Xue, F. Yuan, L. Tan, Y. Sun, C. Xi, and Y. Xi Construction and characterization of a novel DNA vaccine that is potent antigen-specific tolerizing therapy for experimental arthritis by increasing CD4+CD25+Treg cells and inducing Th1 to Th2 shift in both cells and cytokines Vaccine 27 2009 690 700 doi: S0264-410X(08)01572-7, doi: 10.1016/j.vaccine.2008.11.090
    • (2009) Vaccine , vol.27 , pp. 690-700
    • Song, X.1    Liang, F.2    Liu, N.3    Luo, Y.4    Xue, H.5    Yuan, F.6    Tan, L.7    Sun, Y.8    Xi, C.9    Xi, Y.10
  • 115
    • 55349124006 scopus 로고    scopus 로고
    • The therapeutic effect of vasoactive intestinal peptide on experimental arthritis is associated with CD4+CD25+ T regulatory cells
    • doi: SJI2178 [pii], 10.1111/j.1365-3083.2008.02178.x
    • G. Chen, J. Hao, Y. Xi, W. Wang, Z. Wang, N. Li, and W. Li The therapeutic effect of vasoactive intestinal peptide on experimental arthritis is associated with CD4+CD25+ T regulatory cells Scand. J. Immunol. 68 2008 572 578 doi: SJI2178 [pii], 10.1111/j.1365-3083.2008.02178.x
    • (2008) Scand. J. Immunol. , vol.68 , pp. 572-578
    • Chen, G.1    Hao, J.2    Xi, Y.3    Wang, W.4    Wang, Z.5    Li, N.6    Li, W.7
  • 117
    • 40849120400 scopus 로고    scopus 로고
    • Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
    • doi: S1521-6616(08)00008-9
    • M. Seki, S. Oomizu, K.M. Sakata, A. Sakata, T. Arikawa, K. Watanabe, K. Ito, K. Takeshita, T. Niki, and N. Saita Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis Clin. Immunol. 127 2008 78 88 doi: S1521-6616(08)00008-9, doi: 10.1016/j.clim.2008.01.006
    • (2008) Clin. Immunol. , vol.127 , pp. 78-88
    • Seki, M.1    Oomizu, S.2    Sakata, K.M.3    Sakata, A.4    Arikawa, T.5    Watanabe, K.6    Ito, K.7    Takeshita, K.8    Niki, T.9    Saita, N.10
  • 119
    • 30144433577 scopus 로고    scopus 로고
    • Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: An important factor in pathogenesis, counter-regulated by endogenous IFN-gamma
    • 10.1186/ar1500
    • H. Kelchtermans, B. De Klerck, T. Mitera, M. Van Balen, D. Bullens, A. Billiau, G. Leclercq, and P. Matthys Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma Arthritis Res. Ther. 7 2005 R402 R415 10.1186/ar1500
    • (2005) Arthritis Res. Ther. , vol.7
    • Kelchtermans, H.1    De Klerck, B.2    Mitera, T.3    Van Balen, M.4    Bullens, D.5    Billiau, A.6    Leclercq, G.7    Matthys, P.8
  • 122
    • 77955462438 scopus 로고    scopus 로고
    • Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis
    • doi:10.1136/ard.2009.123422
    • Frey O, Reichel A, Bonhagen K, Morawietz L, Rauchhaus U & Kamradt T Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis. Ann. Rheum. Dis. 69, 1511-1518. doi: 10.1136/ard.2009.123422.
    • Ann. Rheum. Dis. , vol.69 , pp. 1511-1518
    • Frey, O.1    Reichel, A.2    Bonhagen, K.3    Morawietz, L.4    Rauchhaus, U.5    Kamradt, T.6
  • 123
    • 20144370643 scopus 로고    scopus 로고
    • The role of regulatory T cells in antigen-induced arthritis: Aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells
    • 10.1186/ar1484
    • O. Frey, P.K. Petrow, M. Gajda, K. Siegmund, J. Huehn, A. Scheffold, A. Hamann, A. Radbruch, and R. Brauer The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells Arthritis Res. Ther. 7 2005 R291 R301 10.1186/ar1484
    • (2005) Arthritis Res. Ther. , vol.7
    • Frey, O.1    Petrow, P.K.2    Gajda, M.3    Siegmund, K.4    Huehn, J.5    Scheffold, A.6    Hamann, A.7    Radbruch, A.8    Brauer, R.9
  • 125
    • 33847021422 scopus 로고    scopus 로고
    • Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis
    • 10.1002/art.22272
    • L.T. Nguyen, J. Jacobs, D. Mathis, and C. Benoist Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis Arthritis Rheum. 56 2007 509 520 10.1002/art.22272
    • (2007) Arthritis Rheum. , vol.56 , pp. 509-520
    • Nguyen, L.T.1    Jacobs, J.2    Mathis, D.3    Benoist, C.4
  • 126
    • 79251564430 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells control humoral autoimmunity by suppressing the development of long-lived plasma cells
    • doi:10.4049/jimmunol.1002942
    • Jang E, Cho WS, Cho ML, Park HJ, Oh HJ, Kang SM, Paik DJ & Youn J Foxp3+ regulatory T cells control humoral autoimmunity by suppressing the development of long-lived plasma cells. J. Immunol. 186, 1546-1553. doi: 10.4049/jimmunol.1002942.
    • J. Immunol. , vol.186 , pp. 1546-1553
    • Jang, E.1    Cho, W.S.2    Cho, M.L.3    Park, H.J.4    Oh, H.J.5    Kang, S.M.6    Paik, D.J.7    Youn, J.8
  • 127
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
    • DOI 10.1084/jem.20040165
    • M.R. Ehrenstein, J.G. Evans, A. Singh, S. Moore, G. Warnes, D.A. Isenberg, and C. Mauri Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy J. Exp. Med. 200 2004 277 285 10.1084/jem.20040165 (Pubitemid 39031247)
    • (2004) Journal of Experimental Medicine , vol.200 , Issue.3 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 128
    • 33846446041 scopus 로고    scopus 로고
    • Anti-TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β
    • DOI 10.1084/jem.20061531
    • S. Nadkarni, C. Mauri, and M.R. Ehrenstein Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta J. Exp. Med. 204 2007 33 39 10.1084/jem.20061531 (Pubitemid 46148753)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.1 , pp. 33-39
    • Nadkarni, S.1    Mauri, C.2    Ehrenstein, M.R.3
  • 129
    • 25444495492 scopus 로고    scopus 로고
    • + T cells in patients with active rheumatoid arthritis is reduced by infliximab
    • DOI 10.1196/annals.1361.095
    • E. Toubi, A. Kessel, Z. Mahmudov, K. Hallas, M. Rozenbaum, and I. Rosner Increased spontaneous apoptosis of CD4+CD25+ T cells in patients with active rheumatoid arthritis is reduced by infliximab Ann. NY Acad. Sci. 1051 2005 506 514 doi: 1051/1/506, 10.1196/annals.1361.095 (Pubitemid 41362778)
    • (2005) Annals of the New York Academy of Sciences , vol.1051 , pp. 506-514
    • Toubi, E.1    Kessel, A.2    Mahmudov, Z.3    Hallas, K.4    Rozenbaum, M.5    Rosner, I.6
  • 131
    • 33646370647 scopus 로고    scopus 로고
    • hi T-regulatory cells
    • DOI 10.1182/blood-2005-11-4567
    • X. Valencia, G. Stephens, R. Goldbach-Mansky, M. Wilson, E.M. Shevach, and P.E. Lipsky TNF downmodulates the function of human CD4+CD25hi T-regulatory cells Blood 108 2006 253 261 10.1182/blood-2005-11-4567 (Pubitemid 43990636)
    • (2006) Blood , vol.108 , Issue.1 , pp. 253-261
    • Valencia, X.1    Stephens, G.2    Goldbach-Mansky, R.3    Wilson, M.4    Shevach, E.M.5    Lipsky, P.E.6
  • 132
    • 36649003890 scopus 로고    scopus 로고
    • high T-regulatory cells in allergic asthma is subjected to TNF-α modulation
    • DOI 10.1111/j.1398-9995.2007.01526.x
    • Y.L. Lin, C.C. Shieh, and J.Y. Wang The functional insufficiency of human CD4+CD25 high T-regulatory cells in allergic asthma is subjected to TNF-alpha modulation Allergy 63 2008 67 74 doi: ALL1526, 10.1111/j.1398-9995.2007.01526.x (Pubitemid 350198236)
    • (2008) Allergy: European Journal of Allergy and Clinical Immunology , vol.63 , Issue.1 , pp. 67-74
    • Lin, Y.-L.1    Shieh, C.-C.2    Wang, J.-Y.3
  • 134
    • 1842732224 scopus 로고    scopus 로고
    • + Regulatory T Cells in Patients with Multiple Sclerosis
    • DOI 10.1084/jem.20031579
    • V. Viglietta, C. Baecher-Allan, H.L. Weiner, and D.A. Hafler Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis J. Exp. Med. 199 2004 971 979 10.1084/jem.20031579 (Pubitemid 38481088)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.7 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 135
    • 12144249838 scopus 로고    scopus 로고
    • + T-cells from patients with type 1 diabetes
    • DOI 10.2337/diabetes.54.1.92
    • S. Lindley, C.M. Dayan, A. Bishop, B.O. Roep, M. Peakman, and T.I. Tree Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes Diabetes 54 2005 92 99 doi: 54/1/92 (Pubitemid 40105099)
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peatman, M.5    Tree, T.I.M.6
  • 138
    • 0033281490 scopus 로고    scopus 로고
    • Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis
    • DOI 10.1186/ar14
    • L.A. Joosten, E. Lubberts, M.M. Helsen, T. Saxne, C.J. Coenen-de Roo, D. Heinegard, and W.B. Van den Berg Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis Arthritis Res. 1 1999 81 91 (Pubitemid 32223676)
    • (1999) Arthritis Research , vol.1 , Issue.1 , pp. 81-91
    • Joosten, L.A.B.1    Lubberts, E.2    Helsen, M.M.A.3    Saxne, T.4    Coenen-De Roo, C.J.J.5    Heinegard, D.6    Van Den Berg, W.B.7
  • 139
    • 0032839668 scopus 로고    scopus 로고
    • Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA)
    • DOI 10.1046/j.1365-2249.1999.00959.x
    • N. Bessis, J. Honiger, D. Damotte, A. Minty, C. Fournier, D. Fradelizi, and M. Boissier Encapsulation in hollow fibres of xenogeneic cells engineered to secrete IL-4 or IL-13 ameliorates murine collagen-induced arthritis (CIA) Clin. Exp. Immunol. 117 1999 376 382 doi: cei959 (Pubitemid 29343613)
    • (1999) Clinical and Experimental Immunology , vol.117 , Issue.2 , pp. 376-382
    • Bessis, N.1    Honiger, J.2    Damotte, D.3    Minty, A.4    Fournier, C.5    Fradelizi, D.6    Boissier, M.-C.7
  • 140
    • 0034469484 scopus 로고    scopus 로고
    • Gene therapy for established murine collagen-induced arthritis bylocal and systemic adenovirus-madiated delivery of interleukin-4
    • DOI 10.1186/ar104
    • S.H. Kim, C.H. Evans, S. Kim, T. Oligino, S.C. Ghivizzani, and P.D. Robbins Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4 Arthritis Res. 2 2000 293 302 (Pubitemid 32223756)
    • (2000) Arthritis Research , vol.2 , Issue.4 , pp. 293-302
    • Kim, S.H.1    Evans, C.H.2    Kim, S.3    Oligino, T.4    Ghivizzani, S.C.5    Robbins, P.D.6
  • 141
    • 0033676265 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis
    • 10.1038/sj.gt.3301324
    • V. Cottard, D. Mulleman, P. Bouille, M. Mezzina, M.C. Boissier, and N. Bessis Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis Gene Ther. 7 2000 1930 1939 10.1038/sj.gt.3301324
    • (2000) Gene Ther. , vol.7 , pp. 1930-1939
    • Cottard, V.1    Mulleman, D.2    Bouille, P.3    Mezzina, M.4    Boissier, M.C.5    Bessis, N.6
  • 142
    • 0031059255 scopus 로고    scopus 로고
    • Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis: Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction
    • DOI 10.1002/art.1780400209
    • L.A. Joosten, E. Lubberts, P. Durez, M.M. Helsen, M.J. Jacobs, M. Goldman, and W.B. Van den Berg Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction Arthritis Rheum. 40 1997 249 260 (Pubitemid 27114088)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.2 , pp. 249-260
    • Joosten, L.A.B.1    Lubberts, E.2    Durez, P.3    Helsen, M.M.A.4    Jacobs, M.J.M.5    Goldman, M.6    Van Den Berg, W.B.7
  • 143
    • 0035147029 scopus 로고    scopus 로고
    • Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis
    • DOI 10.1002/1529-0131(200101)44:1<3::AID-ANR2>3.0.CO;2-U
    • J.A. Van Roon, F.P. Lafeber, and J.W. Bijlsma Synergistic activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis Arthritis Rheum. 44 2001 3 12 doi: 10.1002/1529-0131(200101)44:1<3::AID-ANR2>3.0.CO;2-U (Pubitemid 32113112)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.1 , pp. 3-12
    • Van Roon, J.A.G.1    Lafeber, F.P.J.G.2    Bijlsma, J.W.J.3
  • 145
    • 33846249233 scopus 로고    scopus 로고
    • Interleukin-17 as a molecular target in immune-mediated arthritis: Immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4
    • DOI 10.1002/art.22311
    • S. Sarkar, L.A. Tesmer, V. Hindnavis, J.L. Endres, and D.A. Fox Interleukin-17 as a molecular target in immune-mediated arthritis: immunoregulatory properties of genetically modified murine dendritic cells that secrete interleukin-4 Arthritis Rheum. 56 2007 89 100 10.1002/art.22311 (Pubitemid 46106181)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.1 , pp. 89-100
    • Sarkar, S.1    Tesmer, L.A.2    Hindnavis, V.3    Endres, J.L.4    Fox, D.A.5
  • 146
    • 0035713019 scopus 로고    scopus 로고
    • Collagen II-pulsed antigen-presenting cells genetically modified to secrete IL-4 down-regulate collagen-induced arthritis
    • DOI 10.1038/sj.gt.3301613
    • L. Guery, G. Chiocchia, F. Batteux, M.C. Boissier, and C. Fournier Collagen II-pulsed antigen-presenting cells genetically modified to secrete IL-4 down-regulate collagen-induced arthritis Gene Ther. 8 2001 1855 1862 10.1038/sj.gt.3301613 (Pubitemid 34141492)
    • (2001) Gene Therapy , vol.8 , Issue.24 , pp. 1855-1862
    • Guery, L.1    Chiocchia, G.2    Batteux, F.3    Boissier, M.-C.4    Fournier, C.5
  • 147
    • 0035284837 scopus 로고    scopus 로고
    • Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4
    • S.H. Kim, S. Kim, C.H. Evans, S.C. Ghivizzani, T. Oligino, and P.D. Robbins Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4 J. Immunol. 166 2001 3499 3505 (Pubitemid 33117354)
    • (2001) Journal of Immunology , vol.166 , Issue.5 , pp. 3499-3505
    • Kim, S.H.1    Kim, S.2    Evans, C.H.3    Ghivizzani, S.C.4    Oligino, T.5    Robbins, P.D.6
  • 148
    • 0033571645 scopus 로고    scopus 로고
    • Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines
    • doi: ji-v163n10p5383
    • A. Finnegan, K. Mikecz, P. Tao, and T.T. Glant Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines J. Immunol. 163 1999 5383 5390 doi: ji-v163n10p5383
    • (1999) J. Immunol. , vol.163 , pp. 5383-5390
    • Finnegan, A.1    Mikecz, K.2    Tao, P.3    Glant, T.T.4
  • 149
    • 0033829035 scopus 로고    scopus 로고
    • Modulation of collagen-induced arthritis by IL-4 and dexamethasone: The synergistic effect of IL-4 and dexamethasone on the resolution of CIA
    • doi: S0162310900002484
    • I. Kang, W.W. Lee, and Y. Lee Modulation of collagen-induced arthritis by IL-4 and dexamethasone: the synergistic effect of IL-4 and dexamethasone on the resolution of CIA Immunopharmacology 49 2000 317 324 doi: S0162310900002484
    • (2000) Immunopharmacology , vol.49 , pp. 317-324
    • Kang, I.1    Lee, W.W.2    Lee, Y.3
  • 151
    • 0031984663 scopus 로고    scopus 로고
    • Effect of a monoclonal antibody against interleukin-4 on collagen-induced arthritis in mice
    • DOI 10.1038/sj.bjp.0701607
    • S. Yoshino Effect of a monoclonal antibody against interleukin-4 on collagen-induced arthritis in mice Br. J. Pharmacol. 123 1998 237 242 10.1038/sj.bjp. 0701607 (Pubitemid 28039549)
    • (1998) British Journal of Pharmacology , vol.123 , Issue.2 , pp. 237-242
    • Yoshino, S.1
  • 152
    • 0036774695 scopus 로고    scopus 로고
    • IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis
    • DOI 10.1002/1521-4141(2002010)32:10<2944::AID-IMMU2944>3.0.CO;2-4
    • L. Svensson, K.S. Nandakumar, A. Johansson, L. Jansson, and R. Holmdahl IL-4-deficient mice develop less acute but more chronic relapsing collagen-induced arthritis Eur. J. Immunol. 32 2002 2944 2953 doi: 10.1002/1521-4141(2002010)32:10<2944::AID-IMMU2944>3.0.CO;2-4 (Pubitemid 35243645)
    • (2002) European Journal of Immunology , vol.32 , Issue.10 , pp. 2944-2953
    • Svensson, L.1    Nandakumar, K.S.2    Johansson, A.3    Jansson, L.4    Holmdahl, R.5
  • 153
    • 20744453370 scopus 로고    scopus 로고
    • Interleukin-4 can be a key positive regulator of inflammatory arthritis
    • DOI 10.1002/art.21104
    • K. Ohmura, L.T. Nguyen, R.M. Locksley, D. Mathis, and C. Benoist Interleukin-4 can be a key positive regulator of inflammatory arthritis Arthritis Rheum. 52 2005 1866 1875 10.1002/art.21104 (Pubitemid 40852896)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.6 , pp. 1866-1875
    • Ohmura, K.1    Nguyen, L.T.2    Locksley, R.M.3    Mathis, D.4    Benoist, C.5
  • 154
    • 0036177816 scopus 로고    scopus 로고
    • The role of IL-4 in regulation of murine collagen-induced arthritis
    • DOI 10.1006/clim.2001.5162
    • L.K. Myers, B. Tang, J.M. Stuart, and A.H. Kang The role of IL-4 in regulation of murine collagen-induced arthritis Clin. Immunol. 102 2002 185 191 10.1006/clim.2001.5162, S1521661601951629 [pii] (Pubitemid 34171518)
    • (2002) Clinical Immunology , vol.102 , Issue.2 , pp. 185-191
    • Myers, L.K.1    Tang, B.2    Stuart, J.M.3    Kang, A.H.4
  • 155
    • 0032520785 scopus 로고    scopus 로고
    • Treatment with an anti-IL-4 monoclonal antibody blocks suppression of collagen-induced arthritis in mice by oral administration of type II collagen
    • S. Yoshino Treatment with an anti-IL-4 monoclonal antibody blocks suppression of collagen-induced arthritis in mice by oral administration of type II collagen J. Immunol. 160 1998 3067 3071 (Pubitemid 28136765)
    • (1998) Journal of Immunology , vol.160 , Issue.6 , pp. 3067-3071
    • Yoshino, S.1
  • 156
    • 0032078435 scopus 로고    scopus 로고
    • Enhancement of T-cell-mediated arthritis in mice by treatment with a monoclonal antibody against interleukin-4
    • DOI 10.1006/cimm.1998.1291
    • S. Yoshino, and J. Yoshino Enhancement of T-cell-mediated arthritis in mice by treatment with a monoclonal antibody against interleukin-4 Cell. Immunol. 185 1998 153 157 doi: S0008-8749(98)91291-6, 10.1006/cimm.1998.1291 (Pubitemid 28280489)
    • (1998) Cellular Immunology , vol.185 , Issue.2 , pp. 153-157
    • Yoshino, S.1    Yoshino, J.2
  • 158
    • 0036838666 scopus 로고    scopus 로고
    • Th2 mediated regulation in RA and the spondyloarthropathies
    • DOI 10.1136/ard.61.11.951
    • J.A. Van Roon, and J.W. Bijlsma Th2 mediated regulation in RA and the spondyloarthropathies Ann. Rheum. Dis. 61 2002 951 954 (Pubitemid 35221679)
    • (2002) Annals of the Rheumatic Diseases , vol.61 , Issue.11 , pp. 951-954
    • Van Roon, J.A.G.1    Bijlsma, J.W.J.2
  • 160
    • 0029841157 scopus 로고    scopus 로고
    • + T cells in the initiation of insulin-dependent diabetes mellitus
    • B. Wang, A. Gonzalez, C. Benoist, and D. Mathis The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus Eur. J. Immunol. 26 1996 1762 1769 10.1002/eji.1830260815 (Pubitemid 26283148)
    • (1996) European Journal of Immunology , vol.26 , Issue.8 , pp. 1762-1769
    • Wang, B.1    Gonzalez, A.2    Benoist, C.3    Mathis, D.4
  • 161
  • 163
    • 0026492104 scopus 로고
    • Immunomodulation of streptococcal cell wall-induced arthritis. Identification of inflammatory cells and regulatory T cell subsets by mercuric chloride and in vivo CD8 depletion
    • 10.1002/eji.1830221210
    • M.F. Van den Broek, E. de Heer, M.C. Van Bruggen, G. de Roo, K. Kleiverda, F. Eulderink, and W.B. Van den Berg Immunomodulation of streptococcal cell wall-induced arthritis. Identification of inflammatory cells and regulatory T cell subsets by mercuric chloride and in vivo CD8 depletion Eur. J. Immunol. 22 1992 3091 3095 10.1002/eji.1830221210
    • (1992) Eur. J. Immunol. , vol.22 , pp. 3091-3095
    • Van Den Broek, M.F.1    De Heer, E.2    Van Bruggen, M.C.3    De Roo, G.4    Kleiverda, K.5    Eulderink, F.6    Van Den Berg, W.B.7
  • 164
    • 0034942508 scopus 로고    scopus 로고
    • Influence of CD4 or CD8 deficiency on collagen-induced arthritis
    • DOI 10.1046/j.1365-2567.2001.01257.x
    • M. Ehinger, M. Vestberg, A.C. Johansson, M. Johannesson, A. Svensson, and R. Holmdahl Influence of CD4 or CD8 deficiency on collagen-induced arthritis Immunology 103 2001 291 300 doi: imm1257 (Pubitemid 32631466)
    • (2001) Immunology , vol.103 , Issue.3 , pp. 291-300
    • Ehinger, M.1    Vestberg, M.2    Johansson, A.C.M.3    Johannesson, M.4    Svensson, A.5    Holmdahl, R.6
  • 166
    • 57649104328 scopus 로고    scopus 로고
    • Inhibitory CD8+ T cells in autoimmune disease
    • doi: S0198-8859(08)00443-6, 10.1016/j.humimm.2008.08.283
    • M. Suzuki, C. Konya, J.J. Goronzy, and C.M. Weyand Inhibitory CD8+ T cells in autoimmune disease Hum. Immunol. 69 2008 781 789 doi: S0198-8859(08)00443-6, 10.1016/j.humimm.2008.08.283
    • (2008) Hum. Immunol. , vol.69 , pp. 781-789
    • Suzuki, M.1    Konya, C.2    Goronzy, J.J.3    Weyand, C.M.4
  • 167
    • 34248173331 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase and tumor-induced tolerance
    • DOI 10.1172/JCI31178
    • D.H. Munn, and A.L. Mellor Indoleamine 2,3-dioxygenase and tumor-induced tolerance J. Clin. Invest. 117 2007 1147 1154 10.1172/JCI31178 (Pubitemid 46718399)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1147-1154
    • Munn, D.H.1    Mellor, A.L.2
  • 168
    • 66049126424 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis
    • 10.1002/art.24446
    • G. Criado, E. Simelyte, J.J. Inglis, D. Essex, and R.O. Williams Indoleamine 2,3-dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis Arthritis Rheum. 60 2009 1342 1351 10.1002/art.24446
    • (2009) Arthritis Rheum. , vol.60 , pp. 1342-1351
    • Criado, G.1    Simelyte, E.2    Inglis, J.J.3    Essex, D.4    Williams, R.O.5
  • 169
    • 64049089798 scopus 로고    scopus 로고
    • Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
    • doi: S1074-7613(09)00142-3, 10.1016/j.immuni.2009.02.007
    • Y. Chung, S.H. Chang, G.J. Martinez, X.O. Yang, R. Nurieva, H.S. Kang, L. Ma, S.S. Watowich, A.M. Jetten, and Q. Tian Critical regulation of early Th17 cell differentiation by interleukin-1 signaling Immunity 30 2009 576 587 doi: S1074-7613(09)00142-3, 10.1016/j.immuni.2009.02.007
    • (2009) Immunity , vol.30 , pp. 576-587
    • Chung, Y.1    Chang, S.H.2    Martinez, G.J.3    Yang, X.O.4    Nurieva, R.5    Kang, H.S.6    Ma, L.7    Watowich, S.S.8    Jetten, A.M.9    Tian, Q.10
  • 172
    • 64849100544 scopus 로고    scopus 로고
    • Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes
    • doi: 182/5/3112, 10.4049/jimmunol.0801967
    • S. Zrioual, R. Ecochard, A. Tournadre, V. Lenief, M.A. Cazalis, and P. Miossec Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes J. Immunol. 182 2009 3112 3120 doi: 182/5/3112, 10.4049/jimmunol.0801967
    • (2009) J. Immunol. , vol.182 , pp. 3112-3120
    • Zrioual, S.1    Ecochard, R.2    Tournadre, A.3    Lenief, V.4    Cazalis, M.A.5    Miossec, P.6
  • 173
    • 77956634447 scopus 로고    scopus 로고
    • New and future agents in the treatment of rheumatoid arthritis
    • R.F. Van Vollenhoven New and future agents in the treatment of rheumatoid arthritis Discov. Med. 9 2010 319 327
    • (2010) Discov. Med. , vol.9 , pp. 319-327
    • Van Vollenhoven, R.F.1
  • 174
    • 0031030787 scopus 로고    scopus 로고
    • A randomized, double-blind study comparing twenty-four-week treatment with recombinant interferon-γ versus placebo in the treatment of rheumatoid arthritis
    • DOI 10.1002/art.1780400110
    • E.M. Veys, C.J. Menkes, and P. Emery A randomized, double-blind study comparing twenty-four-week treatment with recombinant interferon-gamma versus placebo in the treatment of rheumatoid arthritis Arthritis Rheum. 40 1997 62 68 (Pubitemid 27044037)
    • (1997) Arthritis and Rheumatism , vol.40 , Issue.1 , pp. 62-68
    • Veys, E.M.1    Menkes, C.-J.2    Emery, P.3
  • 175
    • 0026767264 scopus 로고
    • Recombinant human interferon gamma in the treatment of rheumatoid arthritis: Double blind placebo controlled study
    • K.P. Machold, K. Neumann, and J.S. Smolen Recombinant human interferon gamma in the treatment of rheumatoid arthritis: double blind placebo controlled study Ann. Rheum. Dis. 51 1992 1039 1043
    • (1992) Ann. Rheum. Dis. , vol.51 , pp. 1039-1043
    • MacHold, K.P.1    Neumann, K.2    Smolen, J.S.3
  • 177
    • 34247247352 scopus 로고    scopus 로고
    • Interferon-γ regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17
    • DOI 10.1002/art.22453
    • C.Q. Chu, D. Swart, D. Alcorn, J. Tocker, and K.B. Elkon Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17 Arthritis Rheum. 56 2007 1145 1151 10.1002/art.22453 (Pubitemid 46608639)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.4 , pp. 1145-1151
    • Chu, C.-Q.1    Swart, D.2    Alcorn, D.3    Tocker, J.4    Elkon, K.B.5
  • 179
    • 59449089262 scopus 로고    scopus 로고
    • High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: Central to rheumatoid arthritis pathogenesis?
    • 10.1186/ar2446
    • R. Thomas, M. Turner, and A.P. Cope High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis? Arthritis Res. Ther. 10 2008 210 10.1186/ar2446
    • (2008) Arthritis Res. Ther. , vol.10 , pp. 210
    • Thomas, R.1    Turner, M.2    Cope, A.P.3
  • 181
    • 77952467331 scopus 로고    scopus 로고
    • Heterogeneity of human effector CD4+ T cells
    • doi: 10.1186/ar2843
    • F. Annunziato, and S. Romagnani Heterogeneity of human effector CD4+ T cells Arthritis Res. Ther. 11 2009 257 doi: 10.1186/ar2843
    • (2009) Arthritis Res. Ther. , vol.11 , pp. 257
    • Annunziato, F.1    Romagnani, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.