Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis

Arthritis and Rheumatism

Volumn 62, Issue 10, 2010, Pages 2953-2962

  Raposo, Bruno R ^a,b   Rodrigues Santos, Paulo ^c   Carvalheiro, Helena ^d   Água Doce, Ana M ^a,e   Carvalho, Lina ^d   Pereira Da Silva, José A ^f   Graça, Luis ^a,e   Souto Carneiro, M Margarida ^a,d  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF LISBON   (Portugal)

^f CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD27 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUCOSE 6 PHOSPHATE ISOMERASE; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MONOCLONAL ANTIBODY CD28; MONOCLONAL ANTIBODY YTS105; MONOCLONAL ANTIBODY YTS169.4; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; INFLAMMATORY INFILTRATE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; POLYARTHRITIS; PRIORITY JOURNAL; SCORING SYSTEM; SYNOVIUM; T LYMPHOCYTE ACTIVATION; THYMECTOMY; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD8; ARTHRITIS; ARTHRITIS, EXPERIMENTAL; CD8-POSITIVE T-LYMPHOCYTES; HUMANS; IMMUNOCONJUGATES; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, TRANSGENIC; SYNOVITIS;

EID: 77957678588     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27729     Document Type: Article

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