Treatment of a Newly Established Transgenic Model of Chronic Arthritis with Nondepleting Anti-CD4 Monoclonal Antibody

Journal of Immunology

Volumn 159, Issue 10, 1997, Pages 5032-5041

  Mauri, Claudia ^a   Chu, Cong Qui Q ^a   Woodrow, David ^b   Mori, Lucia ^c   Londei, Marco ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; COLLAGEN; CYTOKINE; EPITOPE; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD; DBA MOUSE; DISEASE MODEL; DISEASE PREDISPOSITION; DRUG EFFECT; FEMALE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MOUSE; PATHOLOGY; RHEUMATOID ARTHRITIS; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ARTHRITIS, RHEUMATOID; COLLAGEN; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; EPITOPES; FEMALE; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED DBA; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES;

EID: 0031573090     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Feldmann, M., F. M. Brennan, and R. N. Maini. 1996. Role of cytokines in rheumatoid arthritis. Annu. Rev. Immunol. 14:397.
2. Feldmann, M., F. M. Brennan, and R. N. Maini. 1996. Rheumatoid arthritis. Cell 85:307.
3. Trentham, D. E., A. S. Townes, and A. H. Kang. 1977. Autoimmunity to type II collagen an experimental model of arthritis. J. Exp. Med. 146:857.
4. Courtenay, J. S., M. J. Dallman, A. D. Dayan, A. Martin, and B. Mosedale. 1980. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283:666.
5. Boissier, M. C., X. Z. Feng, A. Carlioz, R. Roudier, and C. Fournier. 1987. Experimental autoimmune arthritis in mice. I. Homologous type II collagen is responsible for self-perpetuating chronic polyarthritis. Ann. Rheum. Dis. 46:691.
6. Cathcart, E. S., K. C. Hayes, W. A. Gonnerman, A. A. Lazzari, and C. Franzblau. 1986. Experimental arthritis in a nonhuman primate. I. Induction by bovine type II collagen. Lab. Invest. 54:26.
7. Trentham, D. E. 1982. Collagen arthritis as a relevant model for rheumatoid arthritis. Arthritis Rheum. 25:911.
8. Holmdahl, R., A. Tarkowski, and R. Jonsson. 1991. Involvement of macrophages and dendritic cells in synovial inflammation of collagen induced arthritis in DBA/1 mice and spontaneous arthritis in MRL/lpr mice. Autoimmunity 8:271.
9. Wooley, P. H., H. S. Luthra, J. M. Stuart, and C. S. David. 1981. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J. Exp. Med. 154:688.
10. Haqqi, T. M., S. Banerjee, W. L. Jones, G. Anderson, M. A. Behlke, D. Y. Loh, H. S. Luthra, and C. S. David. 1989. Identification of T-cell receptor V beta deletion mutant mouse strain AU/ssJ (H-2q) which is resistant to collagen-induced arthritis. Immunogenetics 29:180.
11. Banerjee, S., T. M. Haqqi, H. S. Luthra, J. M. Stuart, and C. S. David. 1988. Possible role of V beta T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J. Exp. Med. 167:832.
12. Myers, L. K., E. F. Rosloniec, J. M. Seyer, J. M. Stuart, and A. H. Kang. 1993. A synthetic peptide analogue of a determinant of type II collagen prevents the onset of collagen-induced arthritis. J. Immunol, 150:4652.
13. Myers, L. K., J. M. Seyer, J. M. Stuart, K. Terato, C. S. David, and A. H. Kang. 1993. T cell epitopes of type II collagen that regulate murine collagen-induced arthritis. J. Immunol. 151:500.
14. Haqqi, T. M., G. D. Anderson, S. Banerjee, and C. S. David. 1992. Restricted heterogeneity in T-cell antigen receptor V beta gene usage in the lymph nodes and arthritic joints of mice. Proc. Natl. Acad. Sci. USA 89:1253.
15. Mori, L., H. Loetscher, K. Kakimoto, H. Bluethmann, and M. Steinmetz. 1992. Expression of a transgenic T cell receptor beta chain enhances collagen-induced arthritis. J. Exp. Med. 176:381.
16. Nordling, C., A. Karlsson-Parra, L. Jansson, R. Holmdahl, and L. Klareskog. 1992. Characterization of a spontaneously occurring arthritis in male DBA/1 mice. Arthritis Rheum. 35:717.
17. Miller, E. J. 1972. Structural studies on cartilage collagen employing limited cleavage and solubilization with pepsin. Biochemistry 11:4903.
18. Tomonari, K. 1988. Down-regulation of the T cell receptor by a mitogenic anti-Thy-1 antibody. Eur. J. Immunol. 18:179.
19. Williams, R. O., D. G. Williams, and R. N. Maini. 1992. Anti-type II collagen ELISA: increased disease specificity following removal of anionic contaminants from salt-fractionated type II collagen. J. Immunol. Methods 147:93.
20. Mauri, C., R. O. Williams, M. Walmsley, and M. Feldmann. 1996. Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis. Eur. J. Immunol. 26:1511.
21. Taylor, P. C., C. Plater-Zyberk, and R. N. Maini. 1995. The role of the B cells in the adoptive transfer of collagen-induced arthritis from DBA/1 (H-2q) to SCID (H-2d) mice. Eur. J. Immunol. 25:763.
22. Chu, C. Q., and M. Londei. 1996. Induction of Th2 cytokines and control of collagen-induced arthritis by nondepleting anti-CD4 Abs. J. Immunol. 157:2685.
23. Ridgway, W., and C. G. Fathman. 1996. Anti-CD4 in the treatment of rheumatoid arthritis: a reappraisal. Immunologist 4:203.
24. Wraith, D. C., H. O. McDevitt, L. Steinman, and H. Acha-Orbea. 1989. T cell recognition as the target for immune intervention in autoimmune disease. Cell 57:709.
25. Brocke, S., K. Gijbels, M. Allegretta, I. Ferber, C. Piercy, T. Blankenstein, R. Martin, U. Utz, N. Karin, D. Mitchell, et al. 1996. Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein. Nature 379:343.
26. Williams, R. O., M. Feldmann, and R. N. Maini. 1992. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA 89:9784.
27. Elliott, M. J., R. N. Maini, M. Feldmann, J. R. Kalden, C. Antoni, J. S. Smolen, B. Leeb, F. C. Breedveld, J. D. Macfarlane, H. Bijl, et al. 1994. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 344:1105.
28. Goverman, J., A. Woods, L. Larson, L. P. Weiner, L. Hood, and D. M. Zaller. 1993. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell 72:551.
29. Katz, J. D., B. Wang, K. Haskins, C. Benoist, and D. Mathis. 1993. Following a diabetogenic T cell from genesis through pathogenesis. Cell 74:1089.
30. Kouskoff, V., A. S. Korganow, V. Duchatelle, C. Degott, C. Benoist, and D. Mathis. 1996. Organ-specific disease provoked by systemic autoimmunity. Cell 87:811.
31. Ranges, G. E., S. Fortin, M. T. Barger, S. Sriram, and S. M. Cooper. 1988. In vivo modulation of murine collagen induced arthritis. Int. Rev. Immunol. 4:83.
32. Firestein, G. S., and N. J. Zvaifler. 1990. How important are T cells in chronic rheumatoid synovitis? Arthritis Rheum. 33:768.
33. + T cells in the presence of a nondepleting monoclonal antibody to CD4 induces a Th2-type response in vitro. J. Exp. Med. 182:5.
34. Miller, J. F., and G. Morahan. 1992. Peripheral T cell tolerance. Annu. Rev. Immunol. 10:51.
35. Mannie, M. D., S. K. Rendall, P. Y. Arnold, J. P. Nardella, and G. A. White. 1996. Anergy-associated T cell antigen presentation: a mechanism of infectious tolerance in experimental autoimmune encephalomyelitis. J. Immunol. 157:1062.
36. Schwartz, R. H. 1996. Models of T cell anergy: is there a common molecular mechanism? J. Exp. Med. 184:1.
37. Grewal, I. S., H. G. Foellmer, K. D. Grewal, J. Xu, F. Hardardottir, J. L. Baron, C. A. Janeway, Jr., and R. A. Flavell. 1996. Requirement tor CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalo-myelitis. Science 273:1864.
38. Boissier, M. C., G. Chiocchia, N. Bessis, J. Hajnal, G. Garotta, F. Nicoletti, and C. Fournier. 1995. Biphasic effect of interferon-gamma in murine collagen-induced arthritis. Eur. J. Immunol. 25:1184.
39. Williams, R. O., D. G. Williams, M. Feldmann, and R. N. Maini. 1993. Increased limb involvement in murine collagen-induced arthritis following treatment with anti-interferon-gamma. Clin. Exp. Immunol. 92:323.
40. Erb, K. J., B. Ruger, M. von Brevern, B. Ryffel, A. Schimpl, and K. Rivett. 1997. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. J. Exp. Med. 185:329.