High doses of interleukin-12 inhibit the development of joint disease in DBA/1 mice immunized with type II collagen in complete Freund's adjuvant

European Journal of Immunology

Volumn 26, Issue 1, 1996, Pages 187-191

  Hess, Henry ^a   Gately, Maurice K ^b   Rüde, Erwin ^a   Schmitt, Edgar ^a   Szeliga, Jacek ^a   Germann, Tieno ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

Arthritis; Autoimmunity; Cytokine; Interleukin 12

Indexed keywords

ANTIBODY; COLLAGEN TYPE 2; FREUND ADJUVANT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; RECOMBINANT INTERLEUKIN 12;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTHRITIS; ARTHROPATHY; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; IMMUNIZATION; INCIDENCE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; AUTOANTIBODIES; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DRUG ADMINISTRATION SCHEDULE; FREUND'S ADJUVANT; INCIDENCE; INTERLEUKIN-12; MALE; MICE; MICE, INBRED DBA;

EID: 0030069075     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830260129     Document Type: Article

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