Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis

Arthritis Research

Volumn 1, Issue 1, 1999, Pages 81-91

  Joosten, Leo A B ^a   Lubberts, Erik ^a   Helsen, Monique M A ^a   Saxne, Tore ^a,b   Coenen De Roo, Christina J J ^a,c   Heinegård, Dick ^a,b   Van Den Berg, Wim B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LUND UNIVERSITY   (Sweden)

^c NV ORGANON   (Netherlands)

Author keywords

Bone destruction; Cartilage oligomeric matrix protein levels; collagen induced arthritis; Interleukin 4; Prednisolone

Indexed keywords

BUFFER; CASEIN; COLLAGEN ANTIBODY; COLLAGEN TYPE 2; FREUND ADJUVANT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 4; MATRIX PROTEIN; MONOCLONAL ANTIBODY; P 4153; PREDNISOLONE; PREDNISOLONE HEMISUCCINATE; PROTEOGLYCAN; RECOMBINANT INTERLEUKIN 4; STREPTAVIDIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTHRITIS; ARTICLE; BONE DESTRUCTION; CARTILAGE DEGENERATION; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENTIATION; HISTOPATHOLOGY; INFLAMMATION; JOINT DESTRUCTION; JOINT RADIOGRAPHY; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN BLOOD LEVEL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BONE AND BONES; CARTILAGE; CATTLE; COLLAGEN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-4; JOINTS; MALE; MICE; MICE, INBRED DBA; PREDNISOLONE; SIALOGLYCOPROTEINS;

EID: 0033281490     PISSN: 14659905     EISSN: None     Source Type: Journal    
DOI: 10.1186/ar14     Document Type: Article

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