High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: Central to rheumatoid arthritis pathogenesis?

Arthritis Research and Therapy

Volumn 10, Issue 4, 2008, Pages

  Thomas, Ranjeny ^a   Turner, Malcolm ^a   Cope, Andrew P ^b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR; LYMPHOCYTE ANTIGEN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ANIMAL MODEL; GENE MUTATION; HYPOTHESIS; IMMUNE DYSREGULATION; INFLAMMATION; INNATE IMMUNITY; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PROTEIN SECRETION; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VIRUS INFECTION; ANIMAL; DISEASE MODEL; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ARTHRITIS, RHEUMATOID; DISEASE MODELS, ANIMAL; MICE; NF-KAPPA B; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 59449089262     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2446     Document Type: Review

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