Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine

Journal of Biological Chemistry

Volumn 271, Issue 27, 1996, Pages 16357-16362

  Crawley, James B ^a   Williams, Lynn M ^a   Mander, Tom ^b   Brennan, Fionula M ^a   Foxwell, Brian M J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Cantab Pharmaceuticals Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYTOKINE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MONOKINE; PHOSPHATIDYLINOSITOL 3 KINASE; RAPAMYCIN; WORTMANNIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME SUBUNIT; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DIVISION; CELL LINE; CHROMONES; ENZYME INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-1; INTERLEUKIN-10; INTERLEUKIN-6; KINETICS; LIPOPOLYSACCHARIDES; MAST CELLS; MICE; MORPHOLINES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYENES; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030037906     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.27.16357     Document Type: Article

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