Cutting Edge: IL-26 Signals Through A Novel Receptor Complex Composed of IL-20 Receptor 1 and IL-10 Receptor 2

Journal of Immunology

Volumn 172, Issue 4, 2004, Pages 2006-2010

  Sheikh, Faruk ^a   Baurin, Vitaliy V ^b   Lewis Antes, Anita ^b   Shah, Nital K ^b   Smirnov, Sergey V ^b   Anantha, Shubha ^b   Dickensheets, Harold ^a   Dumoutier, Laure ^d   Renauld, Jean Christophe ^d   Zdanov, Alexander ^c   Donnelly, Raymond P ^a   Kotenko, Sergei V ^b  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE ANTIBODY; CYTOKINE RECEPTOR; DIMER; HETERODIMER; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR 2; INTERLEUKIN 19; INTERLEUKIN 20; INTERLEUKIN 20 RECEPTOR 1; INTERLEUKIN 22; INTERLEUKIN 24; INTERLEUKIN 26; NEUTRALIZING ANTIBODY; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

EID: 10744224062     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.4.2006     Document Type: Article

References (22)

1. Dumoutier, L., and J. C. Renauld. 2002. Viral and cellular interleukin-10 (IL-10)-related cytokines: from structures to functions. Eur. Cytokine Network 13:5.
2. Fickenschet, H., S. Hor, H. Kupers, A. Knappe, S. Wittmann, and H. Sticht. 2002. The interleukin-10 family of cytokines. Trends Immunol. 23:89.
3. Kotenko, S. V., and S. Pestka. 2000. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19:2557.
4. Kotenko, S. V. 2002. The family of IL-10-related cytokines and their receptors: related, but to what extent? Cytokine Growth Factor Rev. 13:223.
5. Renauld, J. C. 2003. Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators. Nat. Rev. Immunol. 3:667.
6. Kotenko, S. V., G. Gallagher, V. V. Baurin, A. Lewis-Antes, M. Shen, N. K. Shah, J. A. Langer, F. Sheikh, H. Dickensheets, and R. P. Donnelly. 2003. IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 4:69.
7. Sheppard, P., W. Kindsvogel, W. Xu, K. Henderson, S. Schlutsmeyer, T. E. Whitmore, R. Kuestner, U. Garrigues, C. Birks, J. Roraback, et al. 2003. IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat. Immunol. 4:63.
8. Knappe, A., S. Hor, S. Wittmann, and H. Fickenscher. 2000. Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J Virol. 74:3881.
9. Wolk, K., S. Kunz, K. Asadullah, and R. Sabat. 2002. Cutting edge: immune cells as sources and targets of the IL-10 family members? J. Immunol. 168:5397.
10. Kotenko, S. V., C. D. Krause, L. S. Izotova, B. P. Pollack, W. Wu, and S. Pestka. 1997. Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J. 16:5894.
11. Kotenko, S. V., L. S. Izotova, O. V. Mirochnitchenko, E. Esterova, H. Dickensheets, R. P. Donnelly, and S. Pestka. 2001. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rβ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J. Biol. Chem. 276:2725.
12. Kotenko, S. V., L. S. Izotova, O. V. Mirochnitchenko, E. Esterova, H. Dickensheets, R. P. Donnelly, and S. Pestka. 2001. Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity. J. Immunol. 166:7096.
13. Dumoutier, L., C. Leemans, D. Lejeune, S. V. Kotenko, and J. C. Renauld. 2001. Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. J. Immunol. 167:3545
14. Gallagher, G., H. Dickensheets, J. Eskdale, L. S. Izotova, O. V. Mirochnitchenko, J. D. Peat, N. Vazquez, S. Pestka, R. P. Donnelly, and S. V. Kotenko. 2000. Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10). Genes Immun. 1:442.
15. Pletnev, S., E. Magracheva, S. Kozlov, G. Tobin, S. V. Kotenko, A. Wlodawet, and A. Zdanov. 2003. Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. Biochemistry 42:12617.
16. Dumoutier, L., D. Lejeune, D. Colau, and J. C. Renauld. 2001. Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22. J. Immunol. 166:7090.
17. Xu, W., S. R. Presnell, J. Parrish-Novak, W. Kindsvogel, S. Jaspers, Z. Chen, S. R. Dillon, Z. Gao, T. Gilbert, K. Madden, et al. 2001. A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist. Proc. Natl. Acad. Sci. USA 98:9511.
18. Aggarwal, S., M. H. Xie, M. Maruoka, J. Foster, and A. L. Gurney. 2001. Acinar cells of the pancreas area target of interleukin-22. J. Interferon Cytokine Res. 21:1047.
19. Blumberg, H., D. Conklin, W. F. Xu, A. Grossmann, T. Brender, S. Carollo, M. Eagan, D. Foster, B. A. Haldeman, A. Hammond, et al. 2001. Irterleukin 20: discovery, receptor identification, and role in epidermal function. Cell 104:9.
20. Wang, M., Z. Tan, R. Zhang, S. V. Kotenko, and P. Liang. 2001. Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 277:7341.
21. Xie, M. H., S. Aggarwal, W. H. Ho, J. Foster, Z. Zhang, J. Stinson, W. I. Wood, A. D. Goddard, and A. L. Gurney. 2000. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275:31335.
22. Liu, L., C. Ding, W. Zeng, J. G. Heuer, J. W. Tetteault, T. W. Noblitt, G. Hangoc, S. Cooper, K. A. Brune, G. Sharma, et al. 2003. Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20. Blood 102:3206.