The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

Journal of Leukocyte Biology

Volumn 76, Issue 2, 2004, Pages 314-321

  Donnelly, Raymond P ^a   Sheikh, Faruk ^a   Kotenko, Sergei V ^b   Dickensheets, Harold ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

1SGF3; Hepatocytes; IFN ; IL 22BP; STAT3 STAT1

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR 2; INTERLEUKIN 22; INTERLEUKIN 26; INTERLEUKIN 28A; INTERLEUKIN 28B; INTERLEUKIN 29; INTERLEULIN 10 RECEPTOR 1; LAMBDA INTERFERON; NEUTRALIZING ANTIBODY; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; CANCER INHIBITION; CARCINOMA CELL; COLORECTAL CARCINOMA; COMPLEX FORMATION; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIGAND BINDING; LIVER CARCINOMA; MOUSE; NONHUMAN; PANCREAS CARCINOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYSTEMATIC REVIEW;

ANIMALS; CYTOKINES; HUMANS; INTERLEUKIN-10 RECEPTOR BETA SUBUNIT; MEMBRANE GLYCOPROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, INTERFERON; RECEPTORS, INTERLEUKIN;

ANIMALIA;

EID: 3442888513     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0204117     Document Type: Conference Paper

References (51)

1. Donnelly, R. P., Dickensheets, H., Finbloom, D. S. (1999) The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J. Interferon Cytokine Res. 19, 563-573.
2. Moore, K. W., de Waal Malefyt, R., Coffman, R. L., O'Garra, A. (2001) Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19, 683-765.
3. Kotenko, S. V., Krause, C. D., Izotova, L. S., Pollack, B. P., Wu, W., Pestka, S. (1997) Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J. 16, 5894-5903.
4. Ho, A. S., Liu, Y., Khan, T. A., Hsu, D. H., Bazan, J. F., Moore, K. W. (1993) A receptor for interleukin-10 is related to interferon receptors. Proc. Natl. Acad. Sci. USA 90, 11267-11271.
5. Fiorentino, D. F., Bond, M. W., Mosmann, T. R. (1989) Two types of mouse T helper cell: IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 170, 2081-2095.
6. Fiorentino, D. F., Zlotnik, A., Vieira, P., Mosmann, T. R., Howard, M., Moore, K. W., O'Garra, A. (1991) IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J. Immunol. 146, 3444-3451.
7. Ding, L., Shevach, E. M. (1992) IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J. Immunol. 148, 3133-3139.
8. de Waal Malefyt, R., Haanen, J., Spits, H., Roncarolo, M., te Velde, A., Figdor, C., Johnson, K., Kastelein, R., Yssel, H., de Vries, J. E. (1991) Interleukin-10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down regulation of class II major histocompatibility complex expression. J. Exp. Med. 174, 915-924.
9. Ding, L., Linsley, P. S., Huang, L., Germain, R. N., Shevach, E. M. (1993) IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J. Immunol. 151, 1224-1234.
10. Rousset, F., Garcia, E., DeFrance, T., Péronne, C., Vezzio, N., Hsu, D-W., Kastelein, R., Moore, K. W., Banchereau, J. (1992) Interleukin-10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl. Acad. Sci. USA 89, 1890-1893.
11. Taga, K., Cherney, B., Tosato, G. (1993) IL-10 inhibits apoptotic cell death in human T cells starved of IL-2. Int. Immunol. 5, 1599-1608.
12. + T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation. J. Immunol. 150, 4754-4765.
13. Taga, K., Mostowski, H., Tosato, G. (1993) Human interleukin-10 can directly inhibit T cell growth. Blood 81, 2964-2971.
14. Liu, Y., Wei, S. H., Ho, A. S., de Waal Malefyt, R., Moore, K. W. (1994) Expression cloning and characterization of a human IL-10 receptor. J. Immunol. 152, 1821-1829.
15. Lutfalla, G., Gardiner, K., Uzé, G. (1993) A new member of the cytokine receptor gene family maps on chromosome 21 at less than 35 kb from IFNαR. Genomics 16, 366-373.
16. Finbloom, D. S., Winestock, K. D. (1995) IL-10 induces tyrosine phosphorylation of Tyk2 and Jak1 and the differential assembly of STAT1 and STAT3 complexes in human T cells and monocytes. J. Immunol. 155, 1079-1090.
17. Weber-Nordt, R. M., Riley, J. K., Greenlund, A. C., Moore, K. W., Darnell, J. E., Schreiber, R. D. (1996) Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain. J. Biol. Chem. 271, 27954-27961.
18. Williams, L., Jaral, G., Smith, A., Finan, P. (2002) IL-10 expression profiling in human monocytes. J. Leukoc. Biol. 72, 800-809.
19. Lang, R., Patel, D., Morris, J. J., Rutschman, R. L., Murray, P. J. (2002) Shaping gene expression in activated and resting primary macrophages by IL-10. J. Immunol. 169, 2253-2263.
20. Takeda, K., Clausen, B. E., Kalsho, T., Tsujimura, T., Terada, N., Forster, I., Akira, S. (1999) Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10, 39-49.
21. Williams, L., Bradley, L., Smith, A., Foxwell, B. (2004) Signal transducer and activator of transcription 3 is the dominant mediator of the antiinflammatory effects of IL-10 in human macrophages. J. Immunol. 172, 567-576.
22. Dumoutier, L., Louahed, J., Renauld, J. C. (2000) Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J. Immunol. 164, 1814-1819.
23. Wolk, K., Kunz, S., Asadullah, K., Sabat, R. (2002) Immune cells as sources and targets of the IL-10 family members. J. Immunol. 168, 5397-5402.
24. Xie, M. H., Aggarwal, S., Ho, W. H., Foster, J., Zhang, Z., Stinson, J., Wood, W. I., Goddard, A. D., Gurney, A. L. (2000) Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275, 31335-31339.
25. Kotenko, S. V., Izotova, L. S., Mirochnitchenko, O. V., Esterova, E., Dickensheets, H., Donnelly, R. P., Pestka, S. (2001) Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rβ) is a common chain of both the IL-10 and IL-22 receptor complexes. J. Biol. Chem. 276, 2725-2732.
26. Lejeune, D., Dumoutier, L., Constantinescu, S., Kruijer, W., Schuringa, J. J., Renauld, J. C. (2002) Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line: pathways that are shared with and distinct from IL-10. J. Biol. Chem. 277, 33676-33682.
27. Crepaldi, L., Gasperini, S., Lapinet, J. A., Calzetti, F., Pinardi, C., Liu, Y., Zurawski, S., de Waal Malefyt, R., Moore, K. W., Cassatella, M. A. (2001) Up-regulation of IL-10R1 expression is required to render human neutrophils fully responsive to IL-10. J. Immunol. 167, 2312-2322.
28. Blumberg, H., Conklin, D., Xu, W. F., Grossmann, A., Brender, T., Carollo, S., Eagan, M., Foster, D., Haldeman, B. A., Hammond, A., Haugen, H., Jelinek, L., Kelly, J. D., Madden, K., Maurer, M. F., Parrish-Novak, J., Prunkard, D., Sexson, S., Sprencher, C., Waggie, K., West, J., Whitmore, T. E., Yao, L., Kuechle, M. K., Dale, B. A., Chandrasekher, Y. A. (2001) Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell 104, 9-19.
29. Dumoutier, L., Van Roost, E., Colau, D., Renauld, J. C. (2000) Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as a hepatocyte-stimulating factor. Proc. Natl. Acad. Sci. USA 97, 10144-10149.
30. Kotenko, S. V., Izotova, L. S., Mirochnitchenko, O. V., Esterova, E., Dickensheets, H., Donnelly, R. P., Pestka, S. (2001) Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity, J. Immunol. 166, 7096-7103.
31. Ito, S., Ansari, P., Sakatsume, M., Dickensheets, H., Vazquez, N., Donnelly, R. P., Larner, A. C., Finbloom, D. S. (1999) Interleukin-10 inhibits expression of both interferon-α- and interferon-γ-inducible genes by suppressing tyrosine phosphorylation of STAT1. Blood 93, 1456-1463.
32. Radaeva, S., Sun, R., Pan, H., Hong, F., Gao, B. (2004) Interleukin-22 (IL-22) plays a protective role in T cell-mediated hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation. Hepatology 39, 1332-1342.
33. Dumoutier, L., Lejeune, D., Colau, D., Renauld, J. C. (2001) Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22. J. Immunol. 166, 7090-7095.
34. Xu, W., Presnell, S. R., Parrish-Novak, J., Kindsvogel, W., Jaspers, S., Chen, Z., Dillon, S. R., Gao, Z., Gilbert, T., Madden, K., Schlutsmeyer, S., Yao, L., Whitmore, T. E. Chandrasekher, Y., Grant, F. J., Maurer, M., Jelinek, L., Storey, H., Brender, T., Hammond, A., Topouzis, S., Clegg, C. H., Foster, D. C. (2001) A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist. Proc. Natl. Acad. Sci. USA 98, 9511-9516.
35. Gruenberg, B. H., Schoenemeyer, A., Weiss, B., Toschi, L., Kunz, S., Wolk, K., Asadullah, K., Sabat, R. (2001) A novel, soluble homologue of the human IL-10 receptor with preferential expression in placenta. Genes Immun. 2, 329-334.
36. Nagalakshmi, M. L., Murphy, E., Mc Clanahan, T., de waal Malefyt, R. (2004) Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization. Int. Immunopharmacol. 4, 577-592.
37. Kotenko, S. V. (2002) The family of IL-10-related cytokines and their receptors: related, but to what extent? Cytokine Growth Factor Rev. 13, 223-240.
38. Sheikh, F., Baurin, V. V., Lewis-Antes, A., Shah, N. K., Smirnov, S. V., Anantha, S., Dickensheets, H., Dumoutier, L., Renauld, J. C., Zdanov, A., Donnelly, R. P., Kotenko, S. V. (2004) Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2. J. Immunol. 172, 2006-2010.
39. Xu, W., Chandrasekher, Y., Haugen, H., Hughes, S., Dillon, S., Sivakumar, Pl, Brender, T., Waggie, K., Yao, L., Schlutsmeyer, S., Anderson, M., Kindsvogel, W., Chen, Z., Blumberg, H., Cooper, K. D., McCormich, T. S., Novak, J., Clegg, C., McKernan, P. A., Foster, D. (2003) IL-20 and IL-22 in psoriasis. Eur. Cytokine Netw. 14, 65.
40. Knappe, A., Hor, S., Wittmann, S., Fickenscher, H. (2000) Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J. Virol. 74, 3881-3887.
41. Pletnev, S., Magracheva, E., Kozlov, S., Tobin, G., Kotenko, S. V., Wlodawer, A., Zdanov, A. (2003) Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20. Biochemistry 42, 12617-12624.
42. Dumoutier, L., Leemans, C., Lejeune, D., Kotenko, S. V., Renauld, J. C. (2001) Cutting edge: STAT activation by IL-19, IL-20 and MDA-7 through IL-20 receptor complexes of two types. J. Immunol. 167, 3545-3549.
43. Wang, M., Tan, Z., Zhang, R., Kotenko, S. V., Liang, P. (2001) Interleukin-24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 277, 7341-7347.
44. Liu, L., Ding, C., Zeng, W., Heuer, J. G., Tetreault, J. W., Noblitt, T. W., Hangoc, G., Cooper, S., Brune, K. A., Sharma, G., Fox, N., Rowlinson, S. W., Rogers, D. P., Witcher, D. R., Lambooy, P. K., Wroblewski, V. J., Miller, J. R., Broxmeyer, H. E. (2003) Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20. Blood 102, 3206-3209.
45. Kotenko, S. V., Gallagher, G., Baurin, V. V., Lewis-Antes, A., Shen, M., Shah, N. K., Langer, J. A., Sheikh, F., Dickensheets, H., Donnelly, R. P. (2003) Interferon-λs mediate antiviral protection through a distinct class II cytokine receptor. Nat. Immunol. 4, 69-77.
46. Sheppard, P., Kindsvogel, W., Xu, W., Henderson, K., Schlutsmeyer, S., Whitmore, T. E., Kuestner, R., Garrigues, U., Birks, C., Roraback, J., Ostrander, C., Dong, D., Shin, J., Presnell, S., Fox, B., Haldeman, B., Cooper, E., Taft, D., Gilbert, T., Grant, F. J., Tackett, M., Krivan, W., McKnight, G., Clegg, C., Foster, D., Klucher, K. M. (2003) IL-28, IL-29 and their class II cytokine receptor IL-28R. Nat. Immunol. 4, 63-68.
47. Coccia, E. M., Severa, M., Giacomini, E., Monneron, D., Remoli, M. E., Julkunen, I., Cella, M., Lande, R., Uzé, G. (2004) Viral infection and Toll-like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur. J. Immunol. 34, 796-805.
48. Diebold, S. S., Montoya, M., Unger, H., Alexopoulou, L., Roy, P., Haswell, L. E., Al-Shamkhani, A., Flavell, R., Borrow, P., Reis e Sousa, C. (2003) Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 424, 324-328.
49. Fish, E. N., Brierley, M. M. (2002) IFN-α/β receptor interactions to biological outcomes: understanding the circuitry. J. Interferon Cytokine Res. 22, 835-845.
50. Brassard, D. L., Grace, M. J., Bordens, R. W. (2002) Interferon-α as an immunotherapeutic protein. J. Leukoc. Biol. 71, 565-581.
51. Gibbs, V. C., Pennica, D. (1997) CRF2-4: isolation of cDNA clones encoding the human and mouse proteins. Gene 186, 97-101.