The oxysterol 27-hydroxycholesterol regulates α-synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen receptors-relevance to Parkinson's disease

Journal of Neurochemistry

Volumn 119, Issue 5, 2011, Pages 1119-1136

  Marwarha, Gurdeep ^a   Rhen, Turk ^b   Schommer, Trevor ^a   Ghribi, Othman ^a  

^a UNIVERSITY OF NORTH DAKOTA   (United States)

^b UNIVERSITY OF NORTH DAKOTA   (United States)

Author keywords

synuclein; 27 hydroxycholesterol; estrogen receptors; liver X receptor; Parkinson's disease; tyrosine hydroxylase

Indexed keywords

26 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; ALPHA SYNUCLEIN; DOPAMINE; ESTRADIOL; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HORMONE RECEPTOR BLOCKING AGENT; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; LIVER X RECEPTOR BLOCKING AGENT; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; NEUROBLASTOMA CELL; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ALPHA-SYNUCLEIN; CELL LINE, TUMOR; DISEASE PROGRESSION; DOWN-REGULATION; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HUMANS; HYDROXYCHOLESTEROLS; NEUROBLASTOMA; ORPHAN NUCLEAR RECEPTORS; PARKINSON DISEASE; SIGNAL TRANSDUCTION; TYROSINE 3-MONOOXYGENASE; UP-REGULATION;

EID: 81255157521     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07497.x     Document Type: Article

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