A distinct role of CD4 + Th17- and Th17-stimulated CD8 + CTL in the pathogenesis of type 1 diabetes and experimental autoimmune encephalomyelitis

Journal of Clinical Immunology

Volumn 31, Issue 5, 2011, Pages 811-826

  Munegowda, Manjunatha Ankathatti ^a,b   Deng, Yulin ^a   Chibbar, Rajni ^b   Xu, Qingyong ^b   Freywald, Andrew ^b   Mulligan, Sean J ^b   Van Drunen Littel Van Den Hurk, Sylvia ^c   Sun, Deming ^d   Xiong, Sidong ^e   Xiang, Jim ^a,b  

^a Saskatoon Cancer Center   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e SOOCHOW UNIVERSITY   (China)

Author keywords

CD8 + CTL; experimental autoimmune encephalitis; pMHC I complex; Th17; type 1 diabetes

Indexed keywords

INTERLEUKIN 17; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; OVALBUMIN; RETINOID RELATED ORPHAN RECEPTOR GAMMA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; IMMUNOPATHOGENESIS; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TH17 CELL;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; CELLS, CULTURED; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GLYCOPROTEINS; INTERLEUKIN-17; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN PROTEINS; OVALBUMIN; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES, CYTOTOXIC; TH17 CELLS;

EID: 80755140087     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-011-9549-z     Document Type: Article

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